TEST BANK microbiology a systems approach cowan 3e chapter016

The major categories of hypersensitivities that typically involve a B-cell immunoglobulin response is/are... Any heightened or inappropriate immune response resulting in tissue damage is

Chapter 016 Disorders in Immunity

Multiple Choice Questions

1 The major categories of hypersensitivities that typically involve a B-cell immunoglobulin response is/are

3 Any heightened or inappropriate immune response resulting in tissue damage is called a/an

6 Bee sting venom is considered to be which type of allergen?

8 Th

e initia

l encounterwit

h anallerge

n

is calle

d th

E

9 A secondencounterwit

h anallerge

n th

at caus

es

a respon

se

is calle

d th

e

A

B

C

D

E

10 Wha

t wil

l beth

e immediat

e actio

n

of anallerge

n when

it enter

s th

at bodyfor

a secondtime?

A

B

D

E

11 Whic

h even

t

is th

e proces

s

of releasin

g chemicalmediators?

A

B

D

E

12 Whic

h even

t occu

rs wit

h th

e sensitizingdo

se

of allergen?

A

B

D

E

13 Whic

h

of th

e following

is no

t apossibl

e sympto

m

of Type

I hypersensitivity?

A

B

C

D

E

14 Histaminecaus

es all th

e followingexce

pt

A

B

C

D

E

15 The chemicalmediat

or th

at caus

es prolonge

d bronchospasm, vascul

ar permeabili

ty an

d muc

us secretion

of asthmati

c

patient

16 Whic

h type(s)

of hypersensitivities

is Ig

G

is involve

d with?

A

B

C

D

E

17 Allergicreactio

ns

to penicilli

ns ar

e considere

d a/an _ hypersensitivit

y

A

B

C

D

E

18 Allergi

es ru

n

in familie

s becaus

e

A

B

C

D

E

19 A chronic, loc

al allergysuch

as ha

y feve

r

is considere

E

20 A systemi

c, sometim

es fat

al reactio

n wit

h airwa

y obstructio

n an

d circulator

y collaps

e

is

A

B

C

D

E

21 A season

al reactio

n

to inhale

d allerge

22 Allof th

e followingar

e associate

d wit

h Ig

E an

d mas

t cel

l mediatedallergyexce

pt

A

B

C

D

E

23 Epinephri

ne

A

B

C

D

E

24 Allergicpatient

s receivingsmall,controlledinjectio

ns

of specific allerge

ns ar

e undergoi

ng

A

B

C

D

E

25 Anantihistaminewil

l

A

B

C

D

E

26 Corticosteroi

ds wil

l

A

B

C

D

E

27 Allof th

e followingar

e involve

d

in Type

2 hypersensitivit

y exce

28 Humanbloo

d type

s involveall th

e followingexce

pt

A

B

C

D

E

29 The seru

m

of

a personwit

h bloo

d type

A, Rh

-wil

l havewhich

of th

e following

?

A

B

C

D

E

30 A personwit

h

O typebloo

d

A

B

C

D

E

31 A personwh

o ha

s an

ti

A an

d an

ti

B seru

m antibodieswil

l havebloo

d ty

32 Transfusio

n

of th

e wron

g bloo

d typeca

n caus

e

A

B

C

D

E

33 A femal

e wh

o

is Rh

–

A

B

C

D

E

34 The potenti

al forhemolyticdisea

se

of th

e newbor

n occu

rs wh

en

A

B

C

D

E

35 Once

a mothe

r ha

s beensensitized

to th

e Rhfact

or

A

B

D

E

36 Whic

h

of th

e following

is no

t tru

e

of TypeIII hypersensitivity?

A

B

C

D

E

37 Whic

h

of th

e following

is no

t amaj

or orga

n th

at ca

n be

a targe

t

of immun

e complexdeposition

?

38 Larg

e quantiti

es

of antibodiesth

at reac

t

to th

e secondentry

of antigenan

d lead

to formation

of antigen-antibod

y complex

es occu

E

39 Contac

t dermatitisinvolve

s

A

B

C

D

E

40 Wha

t coul

d resul

t whengraftedtissu

e such

as bonemarrowcontai

ns passenge

r lymphocytes

?

A

B

C

D

E

41 Tissu

e transplante

d fro

m on

e bodysit

e on

a patie

nt

to

a differe

nt bodysit

e onth

at patie

nt

is calle

d a/

an

A

B

C

D

E

42 Wha

t involve

s determinatio

n

of dono

r HL

A antigen

s compare

d

to thos

e

of th

e recipient'

s tissue?

A

B

C

D

E

43 Autoimmunity

is typicall

y du

E

44 Autoantibodiescaus

e tissu

e injur

y

in all th

e followingdisease

s exce

pt

A

B

C

D

E

45 Each

of th

e following

is anautoimmun

e disea

se exce

pt

A

B

C

D

E

46 Myasthen

ia gravi

s disea

se arise

s fro

m th

e productio

n

of autoantibodiesagains

t

A

B

C

D

E

47 In multipl

e sclerosi

s, autoantibodiesattac

k

A

B

C

D

E

48 Whic

h

of th

e following

is no

t atheo

ry

to explai

n th

e origi

n

of autoimmun

e diseases?

A

B

C

D

E

49 Wha

t ca

n be

a consequenc

e

of

a geneticdeficien

cy

in

B cel

l survivalan

d maturity

?

A

B

C

D

E

50 The DiGeorgesyndrom

e

is th

e resul

t

of

A

B

C

D

E

51 Seve

re combine

d immunodeficienci

es (SCIDs) ar

e du

e

to

A

B

C

D

E

52 A secondar

y acquire

d immunodeficienc

D

E

53 Each

of th

e followingca

n resul

t

in acquire

d immun

e deficiencie

s exce

pt

A

B

C

D

E

54 In th

e theo

ry forallergicdesensitization, whichimmunoglobulinbloc

ks th

e allerge

n fro

m bindin

g wit

h IgE?

A

B

C

D

55 Degranulation

of mas

t cel

ls lead

s to:

A

B

C

D

True / False Questions

57 Foodallergi

es includegastrointestin

al symptomsan

d oftenhive

s

Tr

ue False

58 Allergicrhinit

is

is als

o know

n

as asthm

a

Tr

ue False

59 A personwh

o

is Rh

-wil

l haveanti-Rhantibodies

in theirseru

m fro

m earlyinfan

cy

Tr

ue False

60 The tuberculi

n reactio

n develop

s withi

n 30minute

s

of th

e ski

n te

st

in peop

le wit

h pri

or sensitizationdu

e

to tuberculosi

s infectio

n

Tr

ue False

61 Durin

g graftrejectio

n, cytotoxi

c Tcel

ls

of th

e recipie

nt recognizean

d respon

d

to foreigncla

ss

I MHCreceptor

s onth

e graft

ls

Tr

ue False62 The allerge

n

in poiso

n ivyplan

ts

is anoil calle

d urushi

ol

Tr

ue False

63 A xenograft

is grafttissu

e fro

m

a dono

r

of on

e speci

es transplante

d

to

a recipie

nt

of anothe

r speci

es

Tr

ue False

64 Eczem

a

is anautoimmun

e disorde

r

Tr

ue False

65 A vir

al infectio

n ca

n caus

e Type

I diabet

es mellitu

s

Tr

ue False

66 The mos

t commonimmunoglobulindeficien

cy

is anIg

G deficien

cy

Tr

ue False

67 AIDS

is

a secondar

y immunodeficienc

y disea

se th

at affec

ts severaltype

s

of immun

e cel

ls

Tr

ue False

Chapter 016 Disorders in Immunity Key

Multiple Choice Questions

1 Th

e maj

or categorie

s

of hypersensitivitiesth

at typicall

y involve

a B-cel

l immunoglobulinrespon

se is/ar

e

cat ego ries of im mu ne dysf unc tion Lea rnin g Obj ecti ve: 16 02 Ide ntif y the four typ es of ove rrea ctio

n to anti gen s.

2 Whic

h

is mismatched

?

A

B

D

E

Lea rnin g Obj ecti ve: 16 02 Ide ntif y the four typ es of ove rrea ctio

n to anti gen s.

3 An

y heightened

or inappropria

te immun

e respon

se resultin

g

in tissu

e damag

e

is calle

d a/

an

rrea ctio

n to anti gen s.

4 Th

e stud

y

of disease

s associate

d wit

h excess

es an

d deficiencie

s

of th

e immun

e syste

m

is

A

5 Atop

y an

d anaphylax

is ar

e hypersensitivities

in th

e catego

ry

A

B

C

E

Lea rnin g Obj ecti ve: 16 02 Ide ntif y the four typ es of ove rrea ctio

n to anti gen s.

6 Be

e stingveno

m

is considere

d

to bewhichtype

of allergen?

A

B

C

D

Lea rnin g Obj ecti ve: 16 03 Def ne alle rge n and disti ngu ish am ong inh alan t Lea rnin g Obj ecti ve: and con tact ant typ es Lea rnin g Obj ecti ve: ing esta nt

7 Fung

al spor

es an

d anim

al dand

er ar

e considere

d

to bewhichtype

of allergen?

A

B

C

E

Lea rnin g Obj ecti ve: 16 03 Def ne alle rge n and disti ngu ish am ong inh alan t Lea rnin g Obj ecti ve: and con tact ant typ es Lea rnin g Obj ecti ve: ing esta nt

8 Th

e initia

l encounterwit

h anallerge

n

is calle

d th

Lea rnin g Obj ecti ve: 16 04 Des crib e the seq uen ce of eve nts afte r sec ond ary exp osu res to alle rge ns.

9 A secondencounterwit

h anallerge

n th

at caus

es

a respon

se

is calle

d th

e

A

B

C

E

Lea rnin g Obj ecti ve: 16 04 Des crib e the seq uen ce of eve nts afte r sec ond ary exp osu res to alle rge ns.

10 Wha

t wil

l beth

e immediat

e actio

n

of anallerge

n when

it enter

s th

at bodyfor

a secondtime?

A

B

D

Lea rnin g Obj ecti ve: 16 04 Des crib e the seq uen ce of eve nts afte r sec ond ary exp osu res to alle rge ns.

11 Whic

h even

t

is th

e proces

s

of releasin

g chemicalmediators?

A

B.

D

Lea rnin g Obj ecti ve: 16 04 Des crib e the seq uen ce of eve nts afte r sec ond ary exp osu res to alle rge ns.

12 Whic

h even

t occu

rs wit

h th

e sensitizingdo

se

of allergen?

A

B.

C

D

Lea rnin g Obj ecti ve: 16 04 Des crib e the seq uen ce of eve nts afte r sec ond ary exp osu res to alle rge ns.

13 Whic

h

of th

e following

is no

t apossibl

e sympto

m

of Type

I hypersensitivity?

A.B.C

D

E

Lea rnin g Obj ecti ve: 16 02 Ide ntif y the four typ es of ove rrea ctio

n to anti gen s.

14 Histaminecaus

es all th

e followingexce

pt

A

C

D

Lea rnin g Obj ecti ve: 16 04 Des crib e the seq uen ce of eve nts afte r sec ond ary exp osu res to alle rge ns.

15 The chemicalmediat

or th

at caus

es prolonge

d bronchospasm, vascul

ar permeabili

ty an

d muc

us secretion

of asthmati

c

patient

afte r sec ond ary exp osu res to alle rge ns.

16 Whic

h type(s)

of hypersensitivities

is Ig

G

is involve

d with?

A

B

C

E

Lea rnin g Obj ecti ve: 16 01 Na me the two cat ego

ries of im mu ne dysf unc tion

17 Allergicreactio

ns

to penicilli

ns ar

e considere

d a/an _ hypersensitivit

y

A

B

D

E

Lea rnin g Obj ecti ve: 16 02 Ide ntif y the four typ es of ove rrea ctio

n to anti

gen s.

18 Allergi

es ru

n

in familie

s becaus

e

A

C

D

E

Lea rnin g Obj ecti ve: 16 06 Brie fly des crib e two met hod s for dia gno sing alle rgie s.

19 A chronic, loc

al allergysuch

as ha

y feve

r

is considere

d

A.B

C

D

Lea rnin g Obj ecti ve: 16 03 Def ne alle rge n and disti ngu ish am ong inh alan t Lea rnin g Obj ecti ve: ing esta nt and con tact ant typ es.

20 A systemi

c, sometim

es fat

al reactio

n wit

h airwa

y obstructio

n an

d circulator

y collaps

e

is

A.B

E

Lea rnin g Obj ecti ve: 16 05 Expl ain why syst emi c ana phyl axis is so seri ous.

21 A season

al reactio

n

to inhale

d allerge

ecti ve: 16 02 Ide ntif y the four typ es of ove rrea ctio

n to anti gen s.

22 Allof th

e followingar

e associate

d wit

h Ig

E an

d mas

t cel

l mediatedallergyexce

pt

A

B

D

E

Lea rnin g Obj ecti ve: 16 02 Ide ntif y the four typ es of ove rrea ctio

n to anti gen s.

23 Epinephri

ne

A

B

C

E

Lea rnin g Obj ecti ve: 16 07 Disc uss the mec han ism of acti on of

"all erg y sho ts".

24 Allergicpatient

s receivingsmall,controlledinjectio

ns

of specific allerge

ns ar

e undergoi

ng

A

B

D

E

Lea rnin g Obj ecti ve: 16 07 Disc uss the mec han ism of acti on of

"all erg y sho ts".

25 Anantihistaminewil

l

A

B

D

E

Lea rnin

g Obj ecti ve: 16 07 Disc uss the mec han ism of acti on of

"all erg y sho ts".

26 Corticosteroi

ds wil

l

A

B

D

E

Lea rnin

g Obj ecti ve: 16 07 Disc uss the mec han ism of acti on of

"all erg y sho ts".

27 Allof th

e followingar

e involve

d

in Type

2 hypersensitivit

y exce

pt

A.B

C

D

E

Lea rnin g

Obj ecti ve: 16 08 List the maj or im mu ne syst em com pon ent s invo lved in Typ

e II hyp ers ensi tivit y.

28 Humanbloo

d type

s involveall th

e followingexce

pt

A

B

D

Lea rnin g Obj ecti ve: 16 09 Expl ain the basi s for the AB O bloo d gro ups Lea

rnin g Obj ecti ve: and wha t typ

e of anti bod

y to the AB O anti gen s dif ere nt indi vidu als mig ht hav e.

29 The seru

m

of

a personwit

h bloo

d type

A, Rh

-wil

l havewhich

of th

e following

?

A

B

C

Lea rnin g Obj ecti ve: 16 09 Expl ain the basi s for the AB O bloo d gro ups Lea rnin g Obj ecti ve: and wha t typ

e of anti bod

y to the AB O anti gen s dif ere nt indi vidu als mig ht hav e.

30 A personwit

h

O typebloo

d

A

B

D

E

Lea rnin g Obj ecti ve: 16 09 Expl ain the basi s for the AB O bloo

d gro ups Lea rnin g Obj ecti ve: 16 10 Ide ntif y whi ch bloo d typ es are con side red univ ers al don ors and univ ers al reci pie nts Lea rnin g Obj ecti ve: and wha t typ

e of anti bod

y to the AB O anti gen s dif ere nt indi vidu als mig ht hav e.

31 A personwh

o ha

s an

ti

A an

d an

ti

B seru

m antibodieswil

l havebloo

d ty

pe

A.B.C

D

E

Lea rnin g Obj ecti ve: 16 09 Expl ain the basi s for the

AB O bloo d gro ups Lea rnin g Obj ecti ve: 16 10 Ide ntif y whi ch bloo d typ es are con side red univ ers al don ors and univ ers al reci pie nts Lea rnin g Obj ecti ve: and wha t typ

e of anti bod

y to the AB O anti gen s dif ere nt indi vidu als

…

32 Transfusio

n

of th

e wron

g bloo

d typeca

n caus

e

B

D

E

Lea rnin g Obj ecti ve: 16 09 Expl ain the

basi s for the AB O bloo d gro ups Lea rnin g Obj ecti ve: 16 10 Ide ntif y whi ch bloo d typ es are con side red univ ers al don ors and univ ers al reci pie nts Lea rnin g Obj ecti ve: and wha t typ

e of anti bod

y to the AB O anti gen s dif ere nt indi vidu als

…

33 A femal

e wh

o

is Rh

–

A

B

C

D

Lea rnin g Obj ecti ve: 16 11 Expl ain und er wha t circ ums tan ces the Rh fact or can be pro ble mat ic for new bor n bab ies.

34 The potenti

al forhemolyticdisea

se

of th

e newbor

n occu

rs wh

en

A

B

C

D

Lea rnin g Obj ecti ve: 16 11 Expl ain und er wha t circ ums tan ces the Rh fact or can be pro ble mat ic for new bor n bab ies.

35 Once

a mothe

r ha

s beensensitized

to th

e Rhfact

or

A

B.

D

E

Lea rnin g Obj ecti ve: 16 11 Expl ain und er wha t circ ums tan ces the Rh fact or can be pro ble mat ic for new bor n bab ies.

36 Whic

h

of th

e following

is no

t tru

e

of TypeIII hypersensitivity?

A.

B

C

E

Lea rnin g Obj ecti ve: 16 12 Spe cify how Typ

e III hyp ers ensi tivit

y is simi lar to Lea rnin

g Obj ecti ve: 16 13 Pro vide hig hlig hts abo ut the Arth us rea ctio n and ser um sick nes s Lea rnin g Obj ecti ve: Typ

e II hyp ers ensi tivit y Lea rnin g Obj ecti ve: and also dif ers fro m

37 Whic

h

of th

e following

is no

t amaj

or orga

n th

at ca

n be

a targe

t

of immun

e complexdeposition

?

B

C

D.E

Lea rnin g Obj ecti ve: 16 12 Spe cify how Typ

e III hyp ers ensi tivit

y is simi lar to Lea rnin g Obj ecti ve: Typ

e II hyp ers ensi tivit y Lea

rnin g Obj ecti ve: and also dif ers fro m

38 Larg

e quantiti

es

of antibodiesth

at reac

t

to th

e secondentry

of antigenan

d lead

to formation

of antigen-antibod

y complex

es occu

E

Lea rnin g Obj ecti ve: 16 12 Spe cify how Typ

e III hyp ers ensi tivit

y is simi lar to Lea rnin g Obj ecti ve: 16 13 Pro vide hig hlig hts abo ut the Arth us rea ctio n and ser um sick nes s Lea rnin g Obj ecti ve: Typ

e II hyp ers

ensi tivit y Lea rnin g Obj ecti ve: and also dif ers fro m

39 Contac

t dermatitisinvolve

s

A

B

D

E

Lea rnin g Obj ecti ve: 16 14

Des crib e the pat hog ene sis of con tact der mat itis.

40 Wha

t coul

d resul

t whengraftedtissu

e such

as bonemarrowcontai

ns passenge

r lymphocytes

?

B

C

D

Lea rnin g Obj ecti ve: 16 15 Pro vide the na mes for 4 dif ere nt sou rces of graf t mat eria l.

41 Tissu

e transplante

d fro

m on

e bodysit

e on

a patie

nt

to

a differe

nt bodysit

e onth

at patie

nt

is calle

d a/

an

A

42 Wha

t involve

s determinatio

n

of dono

r HL

A antigen

s compare

d

to thos

e

of th

e recipient'

s tissue?

A

Obj ecti ve: 16 15 Pro vide the na mes for 4 dif ere nt sou rces of graf t mat eria l.

43 Autoimmunity

is typicall

y du

Lea rnin g Obj ecti ve: 16 16 Na me

& des crib

e at leas

t 3 dif ere nt the orie

s of aut oim mu nity.

44 Autoantibodiescaus

e tissu

e injur

y

in all th

e followingdisease

s exce

pt

A

B

D

E

Lea rnin g Obj ecti ve: 16 16 Na me

& des crib

e at leas

t 3 dif ere nt the orie

s of aut oim mu nity Lea rnin g Obj ecti ve: 16 17 Des crib e the pat hog ene

sis of at leas

t 3 aut oim mu ne dise ase s.

45 Each

of th

e following

is anautoimmun

e disea

se exce

pt

A

B

D

E

Lea rnin g Obj ecti ve: 16 16 Na me

& des crib

e at leas

t 3 dif ere nt the orie

s of aut oim mu nity Lea rnin g obje ctiv e: 16 17 Des crib e the pat hog ene