Pathology at First GlanceHomeostasis: internal stability of the body Pathology: abnormal condition causing measurable changes in structure and function Pathogenesis: development of di
Trang 1Chapter 1
Introduction to Disease
Trang 2Pathology at First Glance
Homeostasis: internal stability of the body
Pathology: abnormal condition causing
measurable changes in structure and function
Pathogenesis: development of disease in
stages
Trang 3Pathology at First Glance (cont’d.)
Syndrome: Defined collection of signs and
symptoms that characterize a condition
Diagnosis: Use of scientific or clinical methods
to determine nature of the disease Basis for
treatment based on exam, signs, symptoms
history, lab data, diagnostic tests.
Prognosis: Predicted course and outcome.
Trang 4Describing Disease
Signs
Abnormal objective findings
Examples: redness, swelling, purulent discharge,
fever, pulse, pallor
Symptoms
Subjective patient reports
Examples: difficulty swallowing, pain, fatigue,
headache, dizziness, itching
Trang 5Describing Disease (cont)
Acute Illness
onset is usually abrupt
symptoms present themselves over hours to days
duration brief (<6 months)
Chronic Illness
onset is slower
symptoms persist from acute/subacute phases
duration indefinite (> 6 months)
Trang 6Disease
Remission: Signs and symptoms subside.
Exacerbation: Signs and symptoms recur
in all severity during this period.
Relapse: Occurs when a disease returns
weeks or months after its apparent
cessation.
Complication: Disease or other abnormal
state developing when a person already
suffers from another disease.
Trang 7Causes of Disease
o Etiology: Cause of a disease.
o Idiopathic: The cause of the disease is not known.
Trang 8Risk factors
Predisposing Factors
gender
lifestyle
environment
heredity
Non-changeable predisposing factors
gender
Trang 9Risk factors (cont)
Changeable predisposing factors
Lifestyle
Environment
Trang 10More Diagnosis Info
Diagnosis of Disease
medical history
physical exam
laboratory tests (blood count, chemistry, etc.)
imaging tests (MRI, CT, X-ray, ultrasound, etc.)
biopsy
miscellaneous tests (pulmonary function, cultures,
etc.)
Trang 11Patient Teaching
Goals of patient teaching
facilitate patient compliance with the medical
treatment plan
clarify information and instructions
foster patient independence and responsibility
establish trusting, therapeutic relationship
Trang 12Patient Teaching (cont’d.)
Additional reasons for patient teaching
ease anxiety
facilitate greater sense of patient control
improve patient/family coping
highlight goals for recovery or acceptance
reduce unnecessary clinic visits and
hospitalizations