Foam Cells Fatty Streak Intermediate Lesion Atheroma Fibrous Plaque Complicated Lesion/Rupture Endothelial Dysfunction Smooth muscle and collagen Growth mainly by lipid accumulati
Trang 2Foam
Cells Fatty Streak Intermediate Lesion Atheroma Fibrous Plaque Complicated Lesion/Rupture
Endothelial Dysfunction
Smooth muscle and collagen
Growth mainly by lipid accumulation Thrombosis, hematoma
Trang 4UA/NSTEMI
Trang 5• Yeh RW et al N Engl J Med 2010;362:2155-2165
Trang 6• Yeh RW et al N Engl J Med 2010;362:2155-2165
Trang 8CK- MB or Troponin Troponin elevated or not
Adapted from Michael Davies
Trang 11•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Trang 13"
Nữ"
"
"
•
•
ESC/ACCF/AHA/WHF Task
Force
Eur Heart J 2007; 28:2525.
Trang 14•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Trang 15Before Infarct After Infarct
Lost Muscle
100
%
50%
0%
Acute chest pain
Shortness of breath
ECG changes
Ischemia
Necrosis AMI = Ischemia + Necrosis
Early injury markers:
Injury markers:
Ventricular overload markers:
Pure risk markers:
Trang 16•
–
–
–
–
Trang 20•
•
•
•
