Foam Cells Fatty Streak Intermediate Lesion Atheroma Fibrous Plaque Complicated Lesion/Rupture Endothelial Dysfunction Smooth muscle and collagen From first decade From third deca
Trang 2Foam
Cells Fatty Streak Intermediate Lesion Atheroma Fibrous Plaque Complicated Lesion/Rupture
Endothelial Dysfunction
Smooth muscle and collagen
From first decade From third decade From fourth decade
Adapted from Stary HC et al Circulation 1995;92:1355-1374
Trang 4UA/NSTEMI
Trang 5• Yeh RW et al N Engl J Med 2010;362:2155-2165
Trang 6• Yeh RW et al N Engl J Med 2010;362:2155-2165
Trang 8CK- MB or Troponin Troponin elevated or not
Adapted from Michael Davies
Trang 15Before Infarct After Infarct
Lost Muscle
• IMA
• Choline Early injury markers:
• Myoglobin
• FABP
• Hs Troponins Injury markers:
• Troponins Ventricular overload markers:
• Natriuretic peptide (BNP) Pure risk markers:
• MPO
• CRP
Trang 16•
– – – –
Trang 20•
•
•
•
Trang 37•
phạm
Trang 42Hamm CW et al Eur Heart J 2011;eurheartj.ehr236
Trang 68Tiêu chí đánh giá điều trị h/c vành cấp