... been found to be the most promising target because XIAP is found to be over-expressed in a variety of can-cers [12–15] In addition, XIAP over-expression also leads to poor prognosis in many cancers ... Apoptosis (XIAP) has been shown to be over-expressed in various cancers leading to poor overall survival However, the role of XIAP in breast cancer from Middle Eastern region has not been fully explored ... for the treatment of cancer because of their ability to be selectively over-expressed in various cancers as compared to their nor-mal counterparts [10, 11] Of the many members of the family, X-linked
Ngày tải lên: 06/08/2020, 04:01
... điều này Ông cho rằng, nguyên nhân là do yếu tố rào cảnchuyển đổi Theo Jones, Mothersbaugh and Beatty (2000) thì rào cản chuyển đổi làbất kì yếu tố nào khiến cho việc chuyển sang nhà cung cấp ... cung cấp thay thế -Sự gắn kết với nhà cung cấp cao -Chi phí chuyển đổi cao Jones, Mothersbaugh and Beatty(2000) -Mối quan hệ giữa khách hàng và nhà cung cấp - Sức hút từ đối thủ cạnh tranhBozzo ... giữa các rào cản chuyển đổi và lòng trung thành củakhách hàng Trước hết là nghiên cứu của Fredy-Roberto Valenzuela (2012) Nghiên cứu này đề xuất 2 dạng rào cản chuyển đổi là rào cản chuyển đổi thuận
Ngày tải lên: 14/12/2013, 01:25
Tài liệu Write Data Validation Code That Can Be Reused in Other Classes docx
... Visual Basic NET Member Override Keywords Keyword Definition Overrides The method overrides the member of the base class with the same signature Overrideable The method can be overridden in a derived ... in a derived class MustOverride The method must be overridden in every derived class NotOverrideable The method can never be overridden by a derived class 15 The last member to implement is the ... member class (InvalidNumberStringException) You might have noticed a symbol before each member declaration This symbol refers to the accessibility of the member A minus sign (-) means the member
Ngày tải lên: 24/12/2013, 06:17
Information Contained in EPA’s Regulatory Impact Analyses Can Be Made Clearer pdf
... convert future benefit or cost estimates to their present value. Trang 5Ten of the RIAs we examined did not include executive summaries, eventhough these summaries can be a significant benefit to ... discount rate andthe value of human life, can have a significant impact on the results of benefit-cost analyses and are important to the regulations being proposed,eight of the RIAs did not identify ... executivesummaries that identify (1) all benefits and costs—even those that cannot be quantified; (2) the range of uncertainties associated with the benefitsand costs; and (3) a comparison of
Ngày tải lên: 06/03/2014, 19:20
Why do Internet services fail, and what can be done about it? ppt
... lookups because those looks were failing, eventually overloading the back-end database, and thus bringing down all services that used the database The email servers became over-loaded because ... protocol over UDP Each cluster is connected to its twin site via the Internet Table 1: Differentiating characteristics of the services described in this study Trang 3below the threshold to be deemed ... difficult to mask is that their fail-ure modes tend to be complex: networking hardware and software can fail outright or more gradually, e.g., become overloaded and start dropping packets Com-bined
Ngày tải lên: 06/03/2014, 21:20
Báo cáo khoa học: Tyrosine-dependent basolateral targeting of human connexin43–eYFP in Madin–Darby canine kidney cells can be disrupted by the oculodentodigital dysplasia mutation L90V ppt
... Madin–Darby canine kidney cellscan be disrupted by the oculodentodigital dysplasia mutation L90V Jana Chtchetinin1,2, Wes D Gifford1,2, Sichen Li1,2, William A Paznekas3, Ethylin Wang Jabs3,4 and Albert ... slight but significant decrease in surface protein degra-dation between WT and the Y286A mutant but not between WT and any of the other mutants We expected to see a greater difference between WT and ... protein; MDCK, Madin–Darby canine kidney; ODDD, oculodentodigital dysplasia; DPBS, dulbecco’s phosphate buffered saline. Trang 2functions [7–10] So far, there have been limited studiesexamining
Ngày tải lên: 23/03/2014, 04:20
Mối liên hệ giữa rào cản chuyển đổi và lòng trung thành của khách hàng tại Ngân hàng Eximbank
... Chi-square có P-value < 0.05 Nếu một mô hình nhận được các giá trị TLI, Trang 13CFI > 0.9 (Bentler & Bonett, 1980); CMIN/df < 2 hoặc có thể < 3(Carmines & McIver,1981); RMSEA ... điều này Ông cho rằng, nguyên nhân là do yếu tố rào cảnchuyển đổi Theo Jones, Mothersbaugh and Beatty (2000) thì rào cản chuyển đổi làbất kì yếu tố nào khiến cho việc chuyển sang nhà cung cấp ... cung cấp thay thế -Sự gắn kết với nhà cung cấp cao -Chi phí chuyển đổi cao Jones, Mothersbaugh and Beatty(2000) -Mối quan hệ giữa khách hàng và nhà cung cấp - Sức hút từ đối thủ cạnh tranhBozzo
Ngày tải lên: 10/04/2014, 11:34
Game on: How gaming can be used to make my product more engaging
... up that extra hour to play that damn game he, or she, loves so much? We can’t answer that, but games can no longer be called refuges from ‘normal’ life; they are as a part of its fabric for ... time. http://venturebeat.com/2011/07/07/ea-scrabble-fifa-multiplayer/ Trang 72Move over NBA, no lockout for pixelsTrang 73At the very forefront of the esports world is an American company called, ... JOHNSONTrang 5@ Trang 6GAMER DESIGNERHow can I use gaming to make my product more engaging? I can’t wait for the next great gaming experience! Trang 7I can’t wait for the next great gaming experience!
Ngày tải lên: 03/07/2014, 14:47
Báo cáo y học: "Bone erosions in rheumatoid arthritis can be repaired through reduction in disease activity with conventional disease-modifying antirheumatic drugs." pot
... We believe we can partially explain this by the fact that more erosions were observed at PIP joints than at other bone sites at baseline The number of 'repairs' becomes higher with greater numbers ... observed between the two groups There were no significant differences between groups in total radiographic score, erosion score, or JSN score at baseline Differences in radiographic progression between ... order was shown to yield a better signal-to-noise ratio when compared with paired reading We chose the chronological approach in the present study because we believe it to be the most sensi-tive
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Granulocyte-CSF induced inflammation-associated cardiac thrombosis in iron loading mouse heart and can be attenuated by statin therapy" pptx
... pro-videin vivo evidence that G-CSF-induced thrombosis can only be ameliorated by simvastatin therapy, but not by tir-ofiban treatment, implying a significant role of inflamma-tion associainflamma-tion ... inflammation-associated cardiac thrombosisin vivo can be attenuated by simvastatin therapy, but not by tirofiban treatment Our results confirmed that G-CSF can inducein vivo cardiac thrombosis through ... However, thrombosis only seen in the cardiac chamber but not other organs (see Supplementary Figure 1), may be due to the fact that macrophage are prone to be deposited in the heart and the liver, yet
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: " Polyclonal antibody against the DPV UL46M protein can be a diagnostic candidate" pot
... protein can be a diagnostic candidate Liting Lu1, Anchun Cheng*1,2,3, Mingshu Wang*1,2, Jinfeng Jiang1, Dekang Zhu1,2, Renyong Jia2, Qihui Luo2, Fei Liu2, Zhengli Chen2, Xiaoyue Chen1,2,3 and Jinlong ... anti-UL46M antibody can be used for further clinical examination and research of DPV Background Duck plague virus (DPV) is a pantropic, generalized infection virus, which can induce an acute, ... 7:83http://www.virologyj.com/content/7/1/83 Page 2 of 10 and no reports have been published concerning the DPV gene UL46 DPV gene transcription can be classified into 3 types: immediate-early (IE), early (E),
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: "Malaria control in Timor-Leste during a period of political instability: what lessons can be learned" docx
... difficulties could have been overcome The RDTs had been brought in to the country soon after the crisis but they were not used Had the RDT tests been done, the parasite species could have been identified ... distributed bed nets, but just for pregnant women and children only 14 families got bed nets, those ones came here first they received bed nets, those ones that came later, they have not received bed ... dengue had also been iden-tified Some training activities could not be implemented because health staff were unable to travel to and from dis-tricts, resulting, for example, in cancelation of
Ngày tải lên: 13/08/2014, 13:21
Báo cáo y học: "The electronic version of this article is the complete one and can be found online at" pps
... Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA ‡ Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA § Howard Hughes Medical Institute, Berkeley, ... desul- furicans are not predicted to belong to the FUR regulon. Another operon in D desulfuricans (392971-392970-392969), encoding three hypothetical proteins, is preceded by two candidate FUR-boxes, ... 2 July 2004 Revised: 20 September 2004 Accepted: 30 September 2004 The electronic version of this article is the complete one and can be found online at http://genomebiology.com/2004/5/11/R90
Ngày tải lên: 14/08/2014, 14:21
Báo cáo y học: "Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution" pdf
... evolution to be very unlikely; instead, these data suggest that the redundancy between these duplicated genes has been maintained over an extensive evolutionary period If there has been selection ... redundancy between these 14 gene pairs has therefore been maintained for more than 80 million years of evolution We believe that it is extremely unlikely that the functional overlap between these ... suggesting that redun-dant functions can be maintained by natural selection over substantial evolutionary times [12,13] In this case, we would expect no difference in age between the sets of duplicated
Ngày tải lên: 14/08/2014, 17:22
Báo cáo y học: "Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase" potx
... slightly smaller than that reported [11] because since the time of that study proteins have been removed from the database and because scores cannot be computed for each gene for each method ... matches, but that there is some subset that can be predicted in this way In order to estimate the number of CDK consensus cluster containing proteins that can be recognized based on sequence alone, ... all contribute significantly, we report NS (not significant) For the other sets, the P values are for the addition of the least significant term to the model The total numbers of proteins in each
Ngày tải lên: 14/08/2014, 17:22
windows xp services that can be disabled
... end-to-end security between clients and servers on TCP/IP networks Maybe TCP/IP security between clients and servers on the network will be impaired Disable If you connect over an IPSec secured ... service can be disabled Server Allows the sharing of local resources such as files and printers, as well as named pipe communication Yes Resources can't be shared, RPC requests will be denied, ... other multimedia devices Maybe Hot buttons controlled by this service will no longer function Disable Required for some "hot buttons" on newer keyboards Can be safely enabled if these
Ngày tải lên: 19/10/2014, 09:30
bài thuyết trình môn nghệ thuật lãnh đạo hãy cân nhắc lại về lòng tin (rethinking trust)
... không xem xét lại sự tin cậy này. Vụ scandal Madoff là một minh chứng cho điều nói trên Nhiều người đã đầu tư tiền tiết kiệm của cả đời họ vào quỹ của Bernie Madoff, tất nhiên là ban đầu họ ... lão luyện và các nhà lãnh đạo doanh nghiệp, bị ru ngủ vào cảm giác về sự đảm bảo một cách sai lầm Bernard Madoff Trang 6VẬY TẠI SAO CHÚNG TA LẠI VƯỚNG VÀO LÒNG TIN ??? Trang 7TÓM TẮT Ý TƯỞNG ... phát triển một cách nhanh chóng với các môn kinh tế thần kinh (neuroeconomists), kinh tế hành vi (behavioral economists,) và tâm lý học sử dụng những công cụ mới và hiệu quả nhất như chụp ảnh bộ
Ngày tải lên: 13/02/2015, 11:14
Strategic environmental assessments may be used to compare different energy scenarios, and a more sustainable power plan can be developed by incorporating the wider impacts considered during the assessment process
... the SEA process can contribute to good governance in the power planning process, and how the capacity of national governments and stakeholders in the power planning process can be strengthened ... social welfare can be increased with appropriate deployment of renewable energy technologies (iv) In their choice of technologies for new power generation, governments should be aware of the ... series The first volume shows how the SEA process can be used for power planning and how capacity for conducting SEAs and the consultation process can be strengthened It highlights the role of SEA
Ngày tải lên: 08/09/2015, 23:32
When telling the world what you want to achieve can be counterproductive
... and Canevello 2008) Self-expression orientation can be heightened by an emphasis on expressive benefits over non-expressive benefits when consumers make decisions For example, a pen can be framed ... would be able to attain, and wanting to be responsible might motivate people to adopt the goal of recycling Thus, it can be argued that goals at varying levels in individual goal systems might be ... values, and abilities For example, being successful and being responsible can be the ideal self-traits that an individual wants to attain These desirable self-traits can shape and give meanings to
Ngày tải lên: 10/09/2015, 09:24
nghiên cứu đánh giá yếu tố mối nguy liên quan đến tỷ lệ chết cá điêu hồng (oreochromis sp ) nuôi bè ở vĩnh long
... district - Vinh Long from July to November 2014 The purpose of the study was to access: risk factors affecting mortality rate, the situation disease occurs in red tilapia cages in Vinh Long province ... tilapia (Oreochromis sp.) in Vinh long province TÓM TẮT Nghiên cứu được tiến hành tại vùng nuôi cá điêu hồng lồng bè trên sông Tiền thuộc huyện Long Hồ - Vĩnh Long từ tháng 7 đến tháng 11 năm ... VĨNH LONG Lê Minh Chánh 1 , Trần Thị Tuyết Hoa 1 Khoa Thuỷ sản, Trường Đại học Cần Thơ ABSTRACT The study was conducted in the region of Red tilapia cage cultured on Tien river, Long
Ngày tải lên: 16/09/2015, 14:09
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