Hội Tim mạch học Việt Nam

Principles of CTO RevascularizationAdvanced Strategies and Technique Identification of the entry with IVUS Distinguish false and true lumen Contralateral angiography Guiding catheter sel

PCI for Chronic Total Occlusions

Suresh G VijanMD., MRCP., FACC., FESC., FEISI

Interventional Cardiologist Lilavati and Fortis hospitals

Mumbai., INDIA

Contralateral angiography Multiple views

Guiding catheter selection Wire/device selection

Incremental stiffness (‟drilling‟) vs „penetration‟

Parallel/Seesaw wiring, STAR IVUS

CTO lesion assessment

 Proximal and distal caps.

 Presence of micro channels.

 Calcification at entry and distal caps.

 Angulation and tortuosity.

 Side branch relationship.

 CTO length (>20 mm).

 Presence and quality of collaterals.

 Disease in donor and distal artery

 Donor and CTO vessel anatomy for guide and guide wire selection.

Angiographic Lesion Morphology

Tapered Stump Functional occlusion Stump absent Total occlusion

Occlusion at side-branch

Bridging collaterals present

Pre or Bridging

Post-branch occlusion collaterals absent

Favor Procedural Success

Does Not Favor Procedural Success

Principles of CTO Revascularization

Advanced Strategies and Technique

Identification of the entry with IVUS Distinguish false and true lumen Contralateral angiography

Guiding catheter selection

Mother-in-Child Technique

Penetration vs Drilling Parallel wire technique Subintimal Tracking and Re-entry

Retrograde crossing Kissing Wire

CART, Reverse CART, Wire Externalization

Basic Concepts of Antegrade CTO PCI

distal cap to focus

on true lumen entry or…

Move gear beyond distal cap to focus

on reentry

NCC 2010

Which wire and when?

Detailed study of cine angiogram-

Micro-channels present in 30-50% cases

Severe fibro calcific segment

Stiff extra support wires -Miracle series 3, 4.5, 6, 12 gm -Cross IT 100, 200, 300

-Intermediate wires -Conquest pro, 8/12 gm

Always start with the soft wires as micro-channels are sometimes not visible and

Primary bend ~ <30°

1-2mm from tip

Secondary bend ~ 10-15°

CTO Guidewires – Tip Shaping

NCC 2010

PCI for CTO When you can’t cross with wire

child, anchor balloons, microcatheters

NCC 2010

First wire

Second wire

Antegrade CTO Wiring

Parallel wire technique

Mother Child Support with Guideliner

Guide catheter

distal tip

GuideLiner

distal tip

St Jude Medical Venture Wire Control Catheter

NCC 2010

Alternatively, PTCA balloon in SB to help

direct wire into proximal cap -”open sesame”

Antegrade CTO Wiring Techniques

IVUS guidance

Blunt occlusion at

sidebranch takeoff

IVUS in false lumen

True lumen

T Suzuki, Toyohashi Heart Center

IVUS guidance in CTO Distinguish false lumen fron true lumen

PCI for CTO When you can’t cross with balloon.

ASAHI TORNUS™

© 2007 Abbott Laboratories AP2925596 Rev A

Asahi Corsair

• After the screw head structure, the grade and the thickness of the polyamide

elastomer resin are gradually increased to provide optimal rigidity and pushability at

the proximal shaft.

For shaft rigidity

Polyamide elastomer

Mother-Child Catheter Technique

Cypher 3.5x23mm

Heartrail 5Fr ST Camino 8Fr JR4.0

Basic Steps in retrograde technique

 Simultaneous bilateral angiograms.

 Identify collateral channels.

 Wiring and device tracking thru collateral

channel.

 Reach the true lumen distal to CTO.

 Cross the CTO – Direct/CART/ Reverse CART.

 Retrograde wire in proximal segment.

 Externalise the guide wire / antegrade wire.

 Dilate and stent the CTO.

NCC 2010

Suitable equipment

approach

Check every 30 mins

PCI for CTOCollateral channels for retrograde approach

NCC 2010

Patterns of Septal Collaterals

Patterns of Epicardial channel

PCI for CTO Wire handling

out the wire and inject 2 cc of dye

Collateral channel isolation

• Selective CC angiography to assess the course and morphology

• Wires: Fielder FC, Fielder XT with Corsair/ Finecross support

NCC 2010

Wiring the collateral channel

Kissing wire technique

NCC 2010

Limitation of Kissing wire

Concept of CART technique

Toyohashi Heart Center

• make connection between antegrade and retrograde

subintimal space utilizing behavior of subintimal

dissection.

• antegrade wire automatically gets into distal true lumen.

( C ontrolled A ntegrade and R etrograde subintimal T racking)

TM

NCC 2010

CART Technique

If antegrade wire is advanced into subintima at the site of retrograde

balloon dilation, it is difficult

to direct the antegrade wire

to the true distal lumen, similar to a difficult situation

in the antegrade approach Collateral dilatation is

needed to pass balloon.

Limitations of CART

NCC 2010

LAD - CTO

Conquest Pro

Tornus

Failed antegrade approach

Conus to LAD

Short distance, large size but torturous and rigid

Choice floppy

Transit

Conus to LAD

Reverse CART

Antegrade 2.5mm

Retro wire : Fielder FC

Retrograde wire crossed to the guiding.

Wire direction was

Cypher 3.5x33mm TAXUS 3.0x32mm

Distal LAD LITA distal

anastomosis

PCI for CTO Conclusion

success rates (90%)

wire

Progress with CTOs over the years

For the past 5-10 years, guided by our Japanese colleagues, the “art” of CTO therapy has become more generalized, now with dedicated equipment

and increasing success!

PCI for CTO Retrograde approach

subintimal

CART with IVUS guidance

Hydrophilic coated guidewire with polymer sleeve Tapered tip to 0.009

(Tip load 8G)

TCT 2010

Other Specialized Microcatheters

• Venture

• Twin-pass

CTO: Key Starting Points

Excellent Guide Support and distal vessel visualization

Select Your Guiding Catheter Carefully

• Use: 7-8F for LCA, and 8F in RCA with

optimal alignment

• Curve 1 size larger for CTO

(e.g., Voda 4 EBU 4.5 – AL 0.75 for RCA…)

• Sideholes recommended for RCA – rarely

necessary in LCA

• But care with proximal disease (RCA)

sometimes an R4 with an anchor is safer

IVUS in false lumen

True lumen

T Suzuki, Toyohashi Heart Center

IVUS guidance in CTO Distinguish false lumen fron true lumen