... day of maximum concentrations of procalcitonin (PCT) and C-reactive protein (CRP) in multiple-trauma patients. Figure 2 Serum levels of procalcitonin (PCT) and C-reactive protein (CRP) in patients ... fractures according to accepted standards of care PCT, CRP, all clinical, microbio-logical, and laboratory data, and all diagnostic and therapeutic options were registered The data analyzed included ... data collected each day for 7 days, and on days 14 and 21 of treatment in the ICU: PCT, CRP, clinical evi-dence and laboratory data of infection, microbiological find-ings, clinical suspicion
Ngày tải lên: 12/08/2014, 23:20
... Adolescents and Adults [42], which classifies patients on the basis of clinical conditions associated with HIV infection and CD4+ T- lymphocyte counts Clinical status and the CDC classification ... hepatocyte-stimulating factor Proc Natl Acad Sci USA 2000, 97:10144-10149 Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F: C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 ... Goudsmit J, Schuitemaker H, Paxton WA: Phenotypic and genotypic comparisons of CCR5- and CXCR4-tropic human immunodeficiency virus type biological clones isolated from subtype C-infected individuals
Ngày tải lên: 12/08/2014, 23:23
Báo cáo y học: "Procalcitonin, lipopolysaccharide-binding protein, interleukin-6 and C-reactive protein in community-acquired infections and sepsis: a prospective study" docx
... 0.05) Receiver-operating characteristic (ROC) curves comparing procalci-tonin (pct), lipopolysaccharide-binding protein (lbp), C-reactive protein (crp), IL-6 (il6), white blood cell (wbc) and neutrophil ... patients and all infected patients (P < 0.05) Receiver-operating characteristic (ROC) curves comparing pro-calcitonin (pct), lipopolysaccharide-binding protein (lbp), C-reactive protein (crp), ... sepsis and severe sepsis (P 2 0.01) Receiver-operat-ing characteristic (ROC) curves comparReceiver-operat-ing procalcitonin (pct), lipopolysaccharide-binding protein (lbp), C-reactive protein (crp),
Ngày tải lên: 12/08/2014, 23:23
Báo cáo khoa học: "Use of plasma C-reactive protein, procalcitonin, neutrophils, macrophage migration inhibitory factor, soluble urokinase-type plasminogen activator receptor, and soluble triggering receptor expressed on myeloid cells-1 in combination to
... diagnostic characteristics Trial registration NCT00389337 AUC = area under the receiver operating characteristic curve; CI = confidence interval; CRP = C-reactive protein; ICU = intensive care unit; ... Sensitivity and specificity of C-reactive protein (CRP), procalcitonin (PCT) and neutrophil count were computed using the predefined cutoff values of 60 mg/l, 0.25 μg/l and 7.5 × 10 9 cells/l, respectively ... sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee Ameri-can College of Chest Physicians/Society of Critical Care
Ngày tải lên: 13/08/2014, 03:20
Báo cáo y học: " Effect of cardiopulmonary bypass on activated partial thromboplastin time waveform analysis, serum procalcitonin and C-reactive protein concentrations" docx
... of CRP, PCT, and BWP in SIRS and No SIRS groupsBox plot showing the evolution of CRP, PCT, and BWP in SIRS and No SIRS groups. BPW = biphasic waveform; CRP = C-reactive protein; PCT = procalcitonin; ... transmittance per- centage per second (%T/s). Diagnosis of SIRS and sepsis SIRS and sepsis diagnosis were established according to the American College of Chest Physicians/Society of Critical Care Medicine ... participate [1]. The term systemic inflammatory response syndrome (SIRS) has been proposed by the American College of Chest Physicians/Society of Criti- cal Care Medicine Consensus Conference Committee
Ngày tải lên: 13/08/2014, 19:20
Effects of C-reactive protein on the expression of matrix metalloproteinases and their inhibitors via Fcγ receptors on 3T3-L1 adipocytes
... 3T3-L1 cells We analyzed the expression of Fcγ receptor (FcγR) IIb and FcγRIII, which are candidates for CRP receptors, and the effects of anti-CD16/CD32 antibodies, which can act as FcγRII and FcγRIII ... Thus, CRP can act as an FcγR ligand [21,24] In human cells, three FcγR classes have been identified: FcγRI (CD64), FcγRII (CD32), and FcγRIII (CD16) [22,23] A study using human histiocytes indicated ... CRP The Ab concentrations used were based on manufacturer instructions CRP and anti-CD16/CD32 Abs did not apparently affect cellular lipid accumulation or architecture (Fig 1) Figure Lipid accumulation
Ngày tải lên: 15/01/2020, 11:37
Longitudinal trajectory patterns of plasma albumin and C-reactive protein levels around diagnosis, relapse, bacteraemia, and death of acute myeloid leukaemia patients
... Coagulase-negative staphylococci 112 (14.3) Streptococcus pneumoniae 12 (1.5) Streptococci, other 10 (1.3) Enterococcus faecalis 134 (17.1) Mono-microbial Gram-negative 308 (37.7) Escherichia coli 127 (16.2) ... biomarker of infectious or cancer episodes in haematological cancer patients, or in any other cancer patient group In the present study, the CRP and PA trajectories around the bacteraemic episodes ... both CRP and PA measured on D0 are shown in Table2, which presents asso-ciations between patient characteristics, CRP, and PA at D0 Regardless of significance, covariates with negative co-efficients
Ngày tải lên: 17/06/2020, 11:33
Protein kinase C α enhances migration of breast cancer cells through FOXC2- mediated repression of p120-catenin
... GGAUUGAGAACUCGACCCU GCGCCUAAGGACCUGGUGA FOXC2 (Dicer-substrates) #1 5 ′ CGACUGCACGAAAUACUGACGUGTC 3′ #2 5 ′ GGUGGUGAUCAAGAGCGAGGCGGCG 3′ 5 ′ CGCCGCCUCGCUCUUGAUCACCACCUU 3′ #3 5 ′ ACAUCAUGACCCUGCGAACGUCGCC ... this study PRKCA (ON-TARGET plus SMARTpool) UAAGGAACCACAAGCAGUA UUAUAGGGAUCUGAAGUUA GAAGGGUUCUCGUAUGUCA UCACUGCUCUAUGGACUUA FOXC2 (ON-TARGET plus SMARTpool) CCUACGACUGCACGAAAUA CCAACGUGCGGGAGAUGUU ... target, FOXC2, enhance migration and invasion in basal A TNBC and endocrine resistant ER+breast cancer We examined the expression pattern of PKCα and FOXC2 in ER+and TNBC breast cancer cell lines
Ngày tải lên: 06/08/2020, 03:32
heat shock protein 90 hsp90 expression and breast cancer
... Heat shock proteins 27 and 70: Anti-apoptotic proteins with tumorigenic properties Cell Cycle 2006, 5, 2592–2601 Calderwood, S.K Heat shock proteins in breast cancer progression—A suitable case ... pancreatic cancer cells Mol Cancer Ther 2008, 7, 162–170 40 Holmes, J.L.; Sharp, S.Y.; Hobbs, S.; Workman, P Silencing of HSP90 cochaperone AHA1 expression decreases client protein activation and ... long-standing approach to treating breast cancer and both estrogen and progesterone receptors are clients of HSP90 [58] Additionally, resistance of breast cancer cells to chemotherapy is known
Ngày tải lên: 02/11/2022, 11:33
C reactive protein can upregulate VEGF expression to promote ADSC induced angiogenesis by activating HIF 1α via CD64PI3kAkt and MAPKERK signaling pathways
... confluence was reached and then incubated in DMEM for 24 hours The CM was then collected for protein assays; increased proteins after CRP treatment are indicated with letters CRP C-reactive protein, ... ligands and binds to the membrane of injured cells as well as the membrane and nuclear components of necrotic and apoptotic cells [1] Baseline circulating concentrations of CRP are signifi-cantly ... factor-1α Background C-reactive protein (CRP), an acute-phase protein and a member of the pentraxin family, members of which are characterized by a cyclic pentameric structure, exhibits Ca2+-dependent
Ngày tải lên: 24/11/2022, 17:38
role of presepsin compared to c reactive protein in sepsis diagnosis and prognostication
... early discrimination between SIRS and sepsis, is mandatory Biomarkers, such as C-reactive protein (CRP) and procalcitonin (PCT), introduced among the diagnostic criteria of sepsis[4], could contribute ... predict higher mortality Ó 2017 The Egyptian College of Critical Care Physicians Production and hosting by Elsevier B.V This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) ... surface membrane of monocytes/ macrophages and serves as a receptor for lipopolysaccharides (LPS) and LPS binding protein (LPBP) complex[6]and react with other conserved surface bacterial ligands
Ngày tải lên: 04/12/2022, 16:15
Occupation and Breast Cancer: A Canadian Case–Control Study docx
... of breast cancer, particularly with respect to having two or more relatives with breast cancer and mutation of the BRCA1 and BRCA2 gene, can explain less than 10% of breast cancer cases.1 Factors ... exposures— chlordane, malathion, and 2,4-dichlorophenoxyacetic acid (2,4-D)—with ele-vated breast cancer risk.32 HEALTHCARE OCCUPATIONS AND BREAST CANCER RISK A number of known or suspected carcinogens ... Sovan, and Peter Infante Funding was provided for the current Lifetime Histories Breast Cancer Research (LHBCR) by the Canadian Breast Cancer Foundation and the Breast Cancer Society of Canada
Ngày tải lên: 06/03/2014, 02:21
tìm hiểu giá trị c reactive protein trong bệnh viêm cầu thận cấp ở trẻ em
... nồng độ của nhiều protein huyết tương được gọi làcác chất phản ứng pha cấp (các protein pha cấp) Các chất phản ứng pha cấp làmột nhóm phức hợp đa chức năng bao gồm các thành phần bổ thể, các proteinđông ... các protein kết hợp kim loại, CRP và các chất khác Các protein nàyđược tổng hợp bởi tế bào gan, dưới sự kích thích bởi các cytokin như IL-1,IL-6,và yếu tố hoại tử u (TNF) [9] Một protein được ... năng CRP có vai trò trực tiếp trong việc làm sạch các tổ chức hoại tử củavật chủ [6] Hiện chưa có chứng cứ rõ ràng về sự gia tăng CRP ở những người bìnhthường hoặc ở những bệnh nhân không mắc bệnh
Ngày tải lên: 31/07/2014, 01:35
NỒNG ĐỘ C-REACTIVE PROTEIN MÁU Ở NGƯỜI BÌNH THƯỜNG pot
... cảnh bệnh viện Chợ Rẫy, đạt các tiêu chuẩn sau đây: Trang 4Không có: cơn đau thắt ngực kiểu thiếu máu cục bộ cơ tim, tiền căn nhồi máu cơ tim, bệnh mạch máu não, bệnh động mạch cảnh, bệnh mạch ... bệnh Crohn, viêm mạch máu toàn thân Chấn thương: phẫu thuật, phỏng, gẫy xương Ung thư: ung thư hạch, carcinoma Các đối tượng hội đủ tiêu chuẩn chọn lựa và không có tiêu chuẩn loại trừ được chọn ... vào nghiên cứu Thực hiện các xét nghiệm: công thức máu, ion đồ, BUN, creatinin, đường huyết đói, bilan mỡ, fibrinogen máu, hs-CRP, ECG, VS, siêu âm tim, chỉ số khối cơ thể (BMI), XQ ngực Định lượng
Ngày tải lên: 01/08/2014, 18:21
NỒNG ĐỘ C-REACTIVE PROTEIN MÁU Ở BỆNH NHÂN HỘI CHỨNG MẠCH VÀNH CẤP pdf
... NỒNG ĐỘ C-REACTIVE PROTEIN MÁU Ở BỆNH NHÂN HỘI CHỨNG MẠCH VÀNH CẤP Tóm tắt Mục đích nghiên cứu: Khảo sát mối liên quan hs-CRP máu hội chứng mạch vành cấp Phương pháp nghiên cứu: cắt ngang, ... Kết luận: hs-CRP máu tăng cao phân nhóm HCMVC (NMCTC có ST chênh lên, NMCTC khơng ST chênh lên, ĐTN khơng ổn định), phân nhóm bệnh nhân có troponin ≥ ng/ml có tương quan thuận chặt chẽ với fibrinogen ... 8.08 (mg/l) có phân phối tần suất lệch phải (2) Nồng độ hsCRP máu nhóm chứng: 1.87 ± 1.18 (mg/l) có phân phối tần suất lệch phải (3) Các phân nhóm NMCT cấp có nồng độ hs-CRP máu cao phân nhóm
Ngày tải lên: 01/08/2014, 19:20
Báo cáo y học: " Discovery of serum biomarkers of alcoholic fatty liver in a rodent model: C-reactive protein" doc
... Ridker PM: Alcohol consumption and plasma concentration of C-reactive protein. Circulation 2003, 107:443-447. 22. Pepys MB, Hirschfield GM: C-reactive protein: a critical update. J Clin Invest ... RESEARC H Open Access Discovery of serum biomarkers of alcoholic fatty liver in a rodent model: C-reactive protein Shu-Lin Liu 1 , Chun-Chia Cheng 2,3 , Chun-Chao Chang 4 , Fu-Der Mai 2,5,6 , Chia-Chi ... suggestions and analysis regarding experimental outcomes as well as revised the article. CCW and CCC: performed tissue sampling and diagnosis. ASH: participated in the collection and diagnosis of clinical
Ngày tải lên: 10/08/2014, 10:20
nghiên cứu nồng độ hs.c-reactive protein huyết tương ở bênh nhân có hội chứng mạch vành cấp tại bệnh viện đa khoa trung ươngcần thơ từ 09 2009-10 2010
... Việt Nam, các công trình nghiên cứu về HCMVC chủ yếu làNMCT có ST chênh lên, còn các công trình nghiên cứu về đau thắt ngựckhông ổn định và nhồi máu cơ tim không ST chênh lên chưa có nhiều hiệnnay ... Nhiều nghiờn cứu khác còn cho thấy có sự tương quan giữa nồng độCRP với kích thước của vùng NMCTC ,mức độ tử vong trongNMCTC[25][39] và có giá trị tiên đoán các biến chứng sau NMCTC, nhất là rối ... LDLc được coi là một tác nhân kích thích viờm, cỏc TBNMcũng nhanh chóng bị thay đổi sau khi bị kích thích bởi các sản phẩm của vitrùng như Herpes virus, Chlamydia Pneumonia hoặc bởi các YTNC nhưthuốc
Ngày tải lên: 17/11/2014, 22:35
Use of IPs cell derived neural stem cells as a cellular vehicle for glioma and breast cancer therapy
... Baculovirus successfully transduces iPSC-NSC iPSCNSCtk/GCV exhibits breast cancer therapeutic effect 73 4.3 Comparison of 3 suicide gene systems: HSVtk, Fcy and CodA 76 4.3.1 Aim 76 4.3.2 iPSC-NSC transduced ... bystander mediated killing effects of HSVtk/GCV, Fcy/5-FC and CodA/5-Fcy/5-FC in co-culture experiments 83 Trang 12Figure 14 HSVtk/GCV and CD/5-FC for breast cancer therapy mediated by iPSC-NSC ... chemo-attractant molecules and their respective receptors including stem cell factor (SCF)/c-kit (Sun L et al., 2004), stomal cell-derived factor (SDF-1), CXC chemokine receptor 4(CXCR4) and vascular endothelial
Ngày tải lên: 09/09/2015, 18:56
GDNF receptor complex in neuronal differentiation and breast cancer
... of other cancers such as oral cancer [115, 116], pancreatic cancer [117-119], lung cancer [119, 120], colorectal cancer [121, 122] and breast cancer Trang 23[123-125] The GDNF receptor complex ... and their receptors in MCF7 human breast cancer cells 41 3.2.2 The effect of GDNF and NTNstimulations in MCF7 42 3.2.3 Specific knockdown of GFRα1 isoforms in MCF7 using 3.2.4 Knockdown effect ... isoform specific neuronal 4.2.4 Profiling of GFRα1 isoforms in clinical breast samples 65 4.2.5 Further study of isoform specific roles in breast cancer 66 4.2.6 GFRα1 in cancer migration and invasiveness
Ngày tải lên: 30/09/2015, 10:11