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BÀI GIẢNG ORGANIC CHEMISTRY chapter5

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NOMENCLATURE OF ALKENES • Ethylene is an acceptable synonym for ethene in the IUPAC system • Propylene, isobutylene and other common names ending in “ylene” are NOT acceptable IUPAC na

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NOMENCLATURE OF ALKENES

Ethylene is an acceptable synonym for ethene in the IUPAC

system

Propylene, isobutylene and other common names ending in

“ylene” are NOT acceptable IUPAC names

The IUPAC name of an alkene is obtained by replacing

the “ane” ending of the corresponding alkane with “ene”

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Note: Alkenes can have geometric isomers

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isomerization

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Eliminations of alkyl halides

Base

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Alkyne hydrogenations

Pd/CaCO 3 + Pb(OAc) 2 / quinoline

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Carbocation rearrangement

More stable

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More stable

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Stereochemistry

Racemic mixture

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Already has 1 asymmetric carbon

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2 asymmetric carbons are created

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Additions of hydrogen bromide (A R )

Radical addition (A R ) – only for HBr

Electrophilic addition (A E)

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Reaction

mechanism:

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Additions of halogens

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Major

addition product – NOT a

dihalide

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Stereochemistry

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21

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2 asymmetric carbons are created

Trans-2-butene Æ meso compound

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Additions of water – hydration reactions

Water is too weakly acidic to allow the hydrogen to act

as an electrophile

H 2 SO 4 , H 3 PO 4 …

Markovnikov’s rule

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Additions of borane: hydroboration-oxidation

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Regioselectivity:

Anti-Markovnikov

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Additions of hydrogen – hydrogenation

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Reaction mechanism:

Syn addition

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Stereochemistry

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31

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Alkene epoxidations – Anti hydroxylations

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Stereochemistry

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Reactions of epoxides

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35

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Stereochemistry Anti additions

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Syn hydroxylations of alkenes

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Reaction mechanism: Syn additions

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Permanganate cleavage of alkenes

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Ozonolysis of alkenes

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In the presence of an oxidizing agent, the products

will be ketones / carboxylic acids

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Polymerizations

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