International Diabetes CenterPreparing the Patient for Insulin Therapy • Understand natural history of diabetes and treatment options SDM... Preparing the Patient for Insulin Therapy •
Trang 1Preparing the Patient
for Insulin Therapy
Trang 2International Diabetes Center
Preparing the Patient for
Insulin Therapy
• Understand natural history of diabetes
and treatment options (SDM)
Trang 3Preparing the Patient for
Trang 4Treat to Target
Fasting and Pre meal glucose 70-140 mg/dL (3.9-7.7 mmol/L)
Postprandial glucose <160 mg/dL (8.8 mmol/L)
(Two hours after the start of a meal the BG should
be no more than 20 to 40 mg/dL or 1.1 to 2.2 mmol/L
above the pre-meal BG)
Bedtime glucose 100-160 mg/dL (5.5-8.9 mmol/L)
International Diabetes Center
Trang 5Preparing the Patient for
Insulin Therapy
• Understand natural history of diabetes and treatment
options (SDM)
• Review targets for blood glucose and HbA1c
• Review insulin therapy options:
physiologic vs conventional
Trang 6International Diabetes Center
Normal Insulin Secretion:
Basal and Bolus Patterns
Basal Insulin Needs
Bolus insulin needs
Trang 7Preparing the Patient for
Insulin Therapy
• Understand natural history of diabetes and treatment
options (SDM)
• Review targets for blood glucose and HbA1c
• Review insulin therapy options: physiologic vs
conventional
• Review benefits and potential side
effects of insulin therapy
Trang 8International Diabetes Center
Benefits and Potential Side Effects
of Insulin Therapy
Benefits:
• Improved well-being; increased energy; decreased
fatigue
• Improved glucose control
• Reduction in risk of complications
Side effects:
• Weight gain
• Hypoglycemia
Trang 9Preparing the Patient for
Insulin Therapy
• Understand natural history of diabetes and treatment
options (SDM)
• Review targets for blood glucose and HbA1c
• Review insulin therapy options: physiologic vs
conventional
• Review benefits and potential side effects of insulin
therapy
• If patient resistant to insulin or needle
phobia, demonstrate insulin injection
using sterile normal saline
Trang 10International Diabetes Center
Preparing the Patient for Insulin
Overcoming Patient Resistance
Misinformation
• Insulin means I have “serious” diabetes
• Insulin causes hypoglycemia
• Insulin causes the complications of diabetes (heart disease, blindness, kidney failure)
• Insulin makes you gain weight
• Injections cause infection
Trang 11Preparing the Patient for Insulin
Overcoming Patient Resistance
Behavioral issues
• Taking insulin is inconvenient
• Taking insulin is embarrassing
• Taking insulin is painful
• Why should I take insulin when I feel well
• I would rather take a pill than take insulin
Trang 12Overcoming Patient Barriers to
• Improved comfort (fine and short
needles), convenience (pens, pumps)
• Severe hypoglycemia rare in type 2
DM (< 3 %)
• Explain that weight gain is seen with
most effective therapies (not insulin alone)
• Glucose lowering is the KEY
Trang 13Starting the Patient on Insulin
• Determine insulin therapy and starting dose
– Physiologic vs conventional
• Teach insulin administration
– Syringe and vial
– Insulin pen
Trang 14International Diabetes Center
Mixing Insulin Using a Syringe and
Vial
Step 1
Step 2
Trang 15Sites for Insulin Administration
From My Insulin Plan, International Diabetes Center, 2001
Trang 16International Diabetes Center
Insulin Injection Technique:
Abdomen
Trang 17Insulin Pens
Trang 18International Diabetes Center
Insulin Pen Injection Technique
Trang 19Starting the Patient on Insulin
• Determine insulin therapy and starting dose
– Physiologic vs conventional
• Teach insulin administration
– Syringe and vial
– Insulin pen
• Review/teach blood glucose monitoring
Trang 20International Diabetes Center
Blood Glucose Monitoring
• To improve clinical decision-making
• To adjust insulin therapy
• To evaluate efficacy of the therapy
• To pin point problems
• To support adherence to regimen
• Feedback for the patient
Trang 21Testing Frequency
Patients on Insulin
• Four times/day recommended
• Testing before each meal and before bedtime
• May also test pre-meal and 2 hours post meal to
evaluate effect of insulin on post-meal glucose
• Modify frequency of monitoring if necessary
• Encourage patients to record values in a record book
Trang 22International Diabetes Center
Blood Glucose Monitoring
Current Technology
Trang 23Glycosylated HbA1c and Average
Blood Glucose Correlation
4% -50 mg/dL (2.8 mmol/L)5% -80 mg/dL (4.4 mmol/L)6% -115 mg/dL (6.3 mmol/L)7% -150 mg/dL (8.3 mmol/L)8% -180 mg/dL (9.9 mmol/L)
Trang 24International Diabetes Center
Starting the Patient on Insulin
• Determine insulin therapy and starting dose
– Physiologic vs conventional
• Teach insulin administration
– Syringe and vial
– Insulin pen
• Review/teach blood glucose monitoring
• Reinforce meal planning using
carbohydrate counting
Trang 26International Diabetes Center
Trang 27– 1 to 2 choices at snacktime, if desired
• Emphasize day-to-day consistency
• Test blood glucose pre/post-meal to assess impact
Trang 28International Diabetes Center
Starting the Patient on Insulin
• Determine insulin therapy and starting dose
– Physiologic vs conventional
– (0.3 u/kg recommended)
• Teach insulin administration
– Syringe and vial
– Insulin pen
• Review/teach blood glucose monitoring
• Reinforce meal planning using carbohydrate counting
• Prevention and treatment of
hypoglycemia
Trang 29• Definition
– Low blood glucose
– Blood glucose < 70 mg/dL (3.8 mmol/L)
• Causes
– Incorrect amount of insulin or oral agents
– Skipped or delayed meal/snack
– Carbohydrate intake less than normal
– Alcohol intake without food
– Physical activity without insulin/food adjustment
Trang 30International Diabetes Center
– Yawning – Difficulty speaking – Poor coordination – Odd behavior/giddy – Irritable/angry
– Unconsciousness,
seizure, death
Trang 31Treatment of Hypoglycemia
Rule of 15
1 Test, if possible
2 Treat with 15 gm CHO
3-4 glucose tabs, 1/2 cup juice
-↑BG 50-75 mg/dL (2.8-4.2 mmol/L)-convenient, readily available choice
3 Wait 15 minutes
4 Test & repeat treatment if glucose
below target
15
Trang 32International Diabetes Center
Trang 33Severe Hypoglycemia
• Requires assistance to treat
• Modify carbohydrate source
– Glucose gel
• Loss of consciousness or seizure
– Use of injected glucagon
Trang 34International Diabetes Center
Glucagon Emergency Kit
• Injection which releases stored glycogen
• To be used if unable to safely ingest oral CHO
• Administered by another person
• Standard doses – 0.5 mg for children/1.0 mg for adults
May be given IM or SC
• May cause nausea/vomiting/headache
• Increase fluids following injection
• Call physician
Trang 35Moderate to Severe Hypoglycemia
Trang 36International Diabetes Center
Hypoglycemia Prevention
• Preventing hypoglycemia is a delicate balancing act
of food, medications and insulin
• Instruct patients to
– Carry carbohydrate at all times
– Test before driving (if possible)
– Wear medical identification
– Teach others how to inject glucagon
Trang 37Starting the Patient on Insulin
• Determine insulin therapy and starting dose
– Physiologic vs conventional
• Teach insulin administration
– Syringe and vial
– Insulin pen
• Review/teach blood glucose monitoring
• Reinforce meal planning using carbohydrate counting
• Prevention and treatment of hypoglycemia
Trang 38International Diabetes Center
Exercise
• Recommendations
– 30 minutes of exercise per day
– Exercise generally lowers blood glucose levels
– May be planned or unplanned
• If possible, test blood glucose before exercise
– BG < 100 mg/dL (5.5 mmol/L), treat hypoglycemia
before exercising Retest if > 30 minutes activity
– BG > 250 mg/dL (13.9 mmol/L), , do not exercise
– BG 100-250 mg/dL (5.5-13.9 mmol/L): Get
moving!
Trang 39Late-Onset Hypoglycemia
• Most common 6-15 hours after exercise
• Due to body’s replacement of muscle glucose stores
• Greater in untrained or inactive
• Greater with strenuous exercise or play
• Not greater with “tighter” blood glucose control
• To Prevent: carbohydrate replacement during/after
exercise, adjust insulin after exercise
Trang 40International Diabetes Center
Carbohydrate & Insulin Adjustment
For Exercise
– 15 gm carbohydrate per hour low intensity exercise
– 30 gm carbohydrate per hour vigorous exercise
Trang 41Starting the Patient on Insulin
• Determine insulin therapy and starting dose
– Physiologic vs Conventional
• Teach insulin administration
– Syringe and vial
– Insulin pen
• Review/teach blood glucose monitoring
• Reinforce meal planning using carbohydrate counting
• Prevention and treatment of hypoglycemia
• Exercise
Trang 42International Diabetes Center
Summary
Introduce insulin early!!!
• Teaching patients to use insulin is more
than how to inject insulin
• Utilize diabetes educators (if available)