... representations The black dots in the RCMs indicate amino acids that are within 6Å of each other in the protein structure The colored (grass-like) areas in the EDPs indicate the energetically ... specific protein folding information: (a) the chaperons (other proteins that assist in the folding of proteins and nucleic acids [4]; and (b) the protein-coding nucleic acid sequences themselves ... connection between mRNA and the corresponding protein structures and indicates that there is protein folding information in nucleic acids that is not present in the genetic code This might suggest an...
Ngày tải lên: 13/08/2014, 23:20
... children. This synthesis summarizes the available evidence concerning the effectiveness of economic instruments (including taxes, price policies and incentives) in containing or reducing food ... concerning the effectiveness of economic instruments in containing or reducing food consumption, particularly of foods high in saturated fats. This synthesis also covers indirect evidence pertaining ... This is a Health Evidence Network (HEN) synthesis report summarizing the available evidence concerning the effectiveness of economic instruments (including taxes, price policies and incentives)...
Ngày tải lên: 17/03/2014, 08:20
đại học thái nguyên khoa công nghệ thông tin how many classrooms are there in thu’s school how many students are there in thu’s school is it in the city unit4 big or small b my class b1 3 floor
... in? * Which class are you in? floor is your classroom? Trang 9Which grade is Phong in? Which class is Phong in? Where is Phong’s classroom?Trang 10Which grade is Thu in?Which class is Thu in? ... Trang 1How many classrooms are there in Thu’s school?How many students are there in Thu’s school? Is it in the city? Trang 2Unit4 Big or smallB - My class (B1 - 3) Trang ... * the first floor (1st) on the first floor * the second floor (2nd) on the second floor Trang 61 Listen and repeatTrang 7Practice the dialogue with a partnerTrang 8• To have + I/ you/ we/ they...
Ngày tải lên: 20/04/2021, 05:37
Tài liệu Báo cáo khoa học: A second novel dye-linked L-proline dehydrogenase complex is present in the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 pptx
... suggests the ADP-ADP-binding motif in the a1 subunit mediates the observed ATP binding, and FMN is likely situated at the interface between the a1 and b1 subunits within the PDH1 complex The dependence ... l-proDH, another, as yet unknown, dye-l-proDH is produced by this organism In the present study, we identified the gene encoding this other enzyme, expressed it in Escherichia coli, and examined the characteristics ... gene using the plasmid pPDH1, but no functional product could be obtained We therefore introduced the gene into pET11a, and were then able to successfully express it and then isolate it using the...
Ngày tải lên: 20/02/2014, 01:20
Proposal for a COUNCIL DECISION authorising enhanced cooperation in the area of financial transaction tax potx
... establishing a common harmonised system of FTT, enhanced cooperation must respect the existing acquis in this area At present, there is only one legal act of the Union pertaining to taxation of financial ... contemplated by the Commission proposal and in the discussions held in Council is covered by the Treaties, as an instance of harmonised indirect taxation within the meaning of Article 113 TFEU According ... requests to the Commission indicating that they wish to establish enhanced cooperation between themselves in the area of the establishment of a common system of FTT and that the Commission should...
Ngày tải lên: 06/03/2014, 19:20
ORIENTATION PAPER prepared in connection with the FP7 2013 Work Programme in the area of Health research docx
... modifications by the Commission, neither the subsequent formal opinion of the Programme Committee nor the final decision of the Commission The final adoption and the publication of the later work ... of the brain, and to study brain diseases including relevant age related illness and search for new therapies The overall aim is to gain a global understanding of the brain by exploring brain ... for therapeutic interventions in groups or categories of rare diseases, facilitating the uptake of personalised medicine into clinical practice and support the competitiveness of Europe in this...
Ngày tải lên: 07/03/2014, 04:20
Processing Fluency and Aesthetic Pleasure: Is Beauty in the Perceiver''''s Processing Experience? pptx
... perceiver Is beauty therefore in the eye of the beholder? In a sense it is, if folk wisdom thinks of the eye as the perceptual processes of the beholder However, beauty "in the eye of the beholder" ... in higher perceptual fiuency, and training in arts gives meaning to complex structures in paintings, poems, or music, which results in an additional increase in processing ease Accordingly, the ... replicating the previous findings In contrast, attributing the affecfive response to the music did eliminate the effect of processing facilitation on liking That is, participants who were informed...
Ngày tải lên: 16/03/2014, 18:20
An Analysis of Business Administration Students Interest in the area of production and Operations pot
... based on the dimensions of the analysis used in the study To answer the research question and to meet the defined goals, the remainder of this paper is divided into four parts Following this introduction, ... for the analysis The fifth and final dimension involved an assessment of the ‘perception of the necessity’ including the area of Business Administration course curricula The evaluation of this ... interest in the area; P4 - The level of students’ personal interest in the area of Production and Operations area is positively influenced by the perception of the area necessity in the course...
Ngày tải lên: 23/03/2014, 05:22
Báo cáo khoa học: Protein kinase Ch activity is involved in the 2,3,7,8tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line potx
... lymphoblastic T-cell line In this report, we provide the following evidence that the protein kinase C (PKC)h activity is func-tionally involved in the AhR-independent signal transduction mechanism that participates ... PKCh) is involved in the TCDD-induced apoptosis of L-MAT cells The incubation of L-MAT cells with 20 nm TCDD resulted in morphological changes characteristic of apoptosis upon staining with the ... inhibitors to determine whether PKC is functionally involved in the L-MAT cell apoptosis induced by TCDD and attempted to identify the specific PKC iso-form(s) involved in the process Pre-treatment...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-jB pathway in skeletal muscle pdf
... [8] The participation of NF-jB signaling in the pathogen-esis of LGMD2A is therefore an interesting possibility The findings obtained in the present study lead to a proposed working hypothesis: in ... binding to titin by improving the accessibility of the titin-binding domain Interestingly, the importance of CARP inter-action for its function was recently demonstrated in a Fig 3 Calpain 3 ... are involved in the transmission of mechanical signals to signaling path-ways In the M line, mechanical stimulation activates the interaction of a protein complex with the kinase domain of titin,...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo khoa học: The GxxxG motif of the transmembrane domain of subunit e is involved in the dimerization/oligomerization of the yeast ATP synthase complex in the mitochondrial membrane doc
... cerevisiae (P81449,Swiss-Prot) are in bold The numbering of the yeast sub-unit e begins at the initiating methionine The star indicates the position of the unique cys-teine residue of the yeast subunit ... two connecting stalks The sector F1 containing the headpiece is a water-soluble unit retaining the ability to hydrolyse ATP when in a soluble form F0is embedded in the membrane and is mainly composed ... helix–helix packing interface involving the amino-acid residues on both sides of the insertion [40] In the other two mutants,the small amino-acid residues Gly15 and Gly19 were replaced by leucine residues...
Ngày tải lên: 31/03/2014, 01:20
báo cáo hóa học: " Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes" pdf
... characterized by hypoxia and ischemia Astroglia play an important role in the initiation and propagation of hypoxia/ischemia-induced inflammation by secreting inflammatory chemokines that attract neutrophils ... consisting of HIF-1α and HIF-1β subunits HIF-1 binds to HIF-1-binding sites in the target genes and activates their transcription We have recently shown that hypoxia-induced expression of IL-1β in ... neutrophils and monocytes into the brain However, triggers of chemokine up-regulation by hypoxia/ischemia in these cells are poorly understood Hypoxia-inducible factor-1 (HIF-1) is a dimeric transcriptional...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Nogo receptor is involved in the adhesion of dendritic cells to myelin" ppt
... NgR1/2 outside the CNS, perhaps in the activation of DCs or in homing of DCs to specific tissues This is supported by the findings of the non-myelin associated proteins B cell activating factor (BAFF) ... in matDCs promotes their adhesion to myelin, resulting in the selective accumulation of matDCs rather than immDC in the myelin debris-containing lesion This would result in further antigen presentation ... transducing subunits of the NgR1 complex remain to be identified Binding of the NgR1 inhibitory complex by MAIFs leads to activation of intracellular RhoA, thereby resulting in axonal outgrowth inhibition,...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học:" Hematopoietic-Prostaglandin D2 synthase through PGD2 production is involved in the adult ovarian physiology" pot
... directly on the FSH-induced FshR promoter act ivity as in the case of inhibin-A [50], or might otherwise act indirectly by increasing FshR mRNA stability, as in the case o f IGF-I [51]. The inhibition ... 7C). In contrast, apoptosis in the GCs of the growing follicles was not modified by the lack of PGD2 signaling (data not shown). As shown in Figure 7D, this increase in cell proliferation is associated ... 10 mg/kg/day were admini- strated for the first experiment and then 1 mg/kg/day was administrated in the following experiments since the three doses had the same impact on the expression of ovarian...
Ngày tải lên: 20/06/2014, 07:20
Báo cáo y học: "JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin" ppsx
... in the inhibi-tory effect of Bee venom on the LPS-induced, and in the inhibitory effect of melittin on the SNP-induced NF-κB in THP-1 cells by 10 μM of SP600125 JNK inhibitor suppressed the inhibitory ... proteosome [13] The resulting free NF-κB is translocated to the nucleus, where it binds to the κB binding sites in the promoter regions of target genes, thereby controls their expression [14] In sev-eral ... of MAP kinase is significant in the regulation of inflammation via controlling the activa-tion of NF-κB and IKKs [19-22] In the present study, we therefore investigated whether melittin and bee...
Ngày tải lên: 11/08/2014, 08:22
báo cáo khoa học: "The grapevine guard cell-related VvMYB60 transcription factor is involved in the regulation of stomatal activity and is differentially expressed in response to ABA and osmotic stress" ppt
... under the same conditions, the lines expressing the VvMYB60 gene displayed a rate of water loss indistinguishable from the one observed in the wild-type, thus demonstrating complete rescue of the ... of the R2R3 clade involved in the regulation of the anthocyanin and pro-anthocyanidin biosynthetic pathway, as the accumulation of these flavonoid com-pounds in fruit tissues is a key determinant ... features discriminate between the Arabi-dopsis and grape MYB60 proteins and other closely related proteins from subgroup 1: a distinctive PHEEG sig-nature in the MYB domain, located in the loop...
Ngày tải lên: 11/08/2014, 11:21
Báo cáo y học: " Inhibition of SOC/Ca2+/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells" pps
... via SOC (SOCE) in the membrane caused by ER depletion is the dominated component of CCE [16] Ca2+ influx via SOC appears to be a determinant in maintaining a sustained increase in [Ca2+]i and ... Nifedipine (1 μM, blocker of VDCC) had no effect on hypoxia-induced cell proliferation These data suggested that sustained entry of extracellular Ca2+ via SOC is the main pathway of maintaining the ... proliferation Sildenafil inhibited the hypoxia-induced increases in cell viability in a dose-dependent manner (Fig 2A) Sildenafil at 100 nM inhibited the hypoxia-induced increase in PASMC (viability...
Ngày tải lên: 12/08/2014, 14:20
GIAO AN LOP 5 TUAN 24 ( 2 BUOI)
... BỊ ĐỒ DÙNG DẠY HỌC: - Hình minh họa SGK trang 98,99 - Chuẩn bò theo nhóm: + Một vài dụng cụ, máy móc sử dụng pin đèn pin, đồng hồ, đồ chơi, pin (một số pin tiểu, pin trung) + Tranh ảnh, áp phích ... c = 5,3m Bài 4: Một lớp học có 19 học sinh trai, số học sinh gái nhiều số học sinh trai bạn Hỏi lớp có phần trăm học sinh trai,bao nhiêu phần trăm học sinh gái? Củng cố- dặn dò: Chuẩn bò sau ... lun tËp cho tõng ®èi tỵng häc sinh cđa líp - Y/c HS tù lµm bµi - Gv theo dâi kÌm cỈp gióp ®ì c¸c ®èi tỵng häc sinh - Tỉ chøc ch÷a bµi * Lu ý c¸c trêng hỵp häc sinh cßn sai nhiỊu Néi dung luyªn...
Ngày tải lên: 29/04/2015, 17:00
SKKN rèn nề nếp cho HS qua mô hình tự quản
... học sinh + Thiết lập, phát triển mối quan hệ lớp với cha mẹ học sinh Sau biện pháp cụ thể mà thực 2.1 Tìm hiểu đối tượng học sinh Để thực tốt chức quản lí, giáo dục học sinh, tìm hiểu học sinh ... Trước sinh hoạt 15 phút đầu giờ, nhóm trưởng chủ động kiểm tra nhắc nhở học sinh việc thực quy định trang phục; tổ trưởng có nhiệm vụ theo dõi nhắc nhở bạn việc thực vệ sinh lớp học Và sinh hoạt ... giáo dục học sinh toàn diện mặt đạt kết cao, học sinh học tốt, giáo viên có hứng thú dạy có hoạt động đồng thầy trò, lớp học sinh động trước hết phải có nề nếp lớp học tốt, học sinh có ý thức...
Ngày tải lên: 28/12/2015, 23:09
Nghiên cứu các yếu tố ảnh hưởng đến sự thỏa mãn của khách hàng qua mô hình chất lượng dịch vụ Servperfvà mô hình giá trị cá nhân dịch vụ Servperf trong ngành siêu thị bán lẻ
... stability in life) ( more pleasurable life) 5 ( more respect from others) ( the feeling that the world is more agreeable) ( more social recognition) ( more status) ( more stimulating and adventurous ... Khi ( more respect from others) CN6 ng tình mua bên ( feeling that the world is more agreeable) CN7 ( more social recognition) CN8 more status) Khi CN9 Khi more stimulating and adventurous life) ... higher integration in my group) better HN11 Mua hàng HN12 giúp ( strengthen my friendship relationships) 3.3 16.0 3.3.1 - Burnstein, 1994) - 3.3.2 S Meyer- ) 0,3 (Jabnoun & ctg, 2003) (Gerbing...
Ngày tải lên: 10/08/2015, 01:20