the nearly unsupervised recognition

... the shape and ori- Trang 28rectifi-is printed The plane parameters are estimated from the orientations of the lines of text in the image and the borders of planar patch, if they are visible The ... rectified and the rectified document images are then fed to the existing generic OCR systems for text conversion The second approach skips the rectification process and schemes to recognize the distorted ... time, the rectification-recognition framework can not work well as the recogni-tion process is generally slowed down by the image transformation operation involved with the rectification process Therefore,

Ngày tải lên: 16/09/2015, 17:13

... specificity The sensitivity and specificity of the yes/no recognition test and the TOMM were compared 16 malingerers failed the cut-off score of the TOMM and 14 failed the cut-off score of the yes/no recognition ... instructed malingerer singled out only the yes/no recognition test Of the non-malingerers, three named the TOMM and one the yes/no recognition test Study 2-discussion In the experimental study, instructed ... participants in the malingering group more often suspected the TOMM to be a test of memory malinge-ring than the yes/no recognition test Table 3 Comparisons of the TOMM and the yes/no recognition

Ngày tải lên: 10/01/2020, 14:43

... of the heat fed into the DHS, which was the result of the wooden biomass co-burning in the heating plant The share of RES in power generation on national level is very important for meeting the ... over the Europe The years before the enforcement are to be used to identify the barriers and to get the construction sector ready for the nZEB challenges Slovenia has officially ac-cepted the ... This part of the legislative statement is transposed to the national regulations by the primary energy indicator and by the share of renewable energy in the total energy use of the building,

Ngày tải lên: 13/01/2020, 19:23

... estimate the density of the classes throughout the data set at only on the labeled data, after which we construct the separating curves Then, from Figure 3 it can be seen that the quality of the classification ... maximizes the width of the dividing strip between classes The problem of the support vector machine method consists in constructing an optimal separating hyperplane The points lying on the edge of the ... patterns, finding associations, etc The development of this area was boosted by the ideas arising from the theory of artificial intelligence The goal of pattern recognition is to classify objects

Ngày tải lên: 12/02/2020, 14:45

... behaviour in their affinity for the NK-1m binding and their potency to stimulate PLC (Fig 4B) Whatever the affinity measured for the NK-1m binding site for these agonists (from 7 pMto 0.54 nM), the corresponding ... to the syntheses of linear tetrapeptides of somato-statin [20] and of cyclic tetrapeptide and pentapeptide analogues of the RGD sequence [19] With the cyclic compounds it is uncertain whether the ... may keep the molecular recognition properties of a-peptides and the biological stability of b-peptides Only a few data have been reported in the literature on the structural properties of these

Ngày tải lên: 08/03/2014, 08:20

... roles in the interaction with the DSK2 homolog from the respective species, we decided to test the hydrophobic patches within the UBLs of the DSK2 homologs for their involvement in the interaction ... ubiquitin-interacting motif. Name a (PLIC1) a The names in parentheses are those for the human homologs b The approximate binding affinity for either the K48- or K63-linked ubiquitin chains is designated ... shown) The divergent structural requirements of the major ubiquitin receptors for ubiquitin chain binding To examine the cross-species divergence of the struc-tural requirements for the recognition

Ngày tải lên: 15/03/2014, 09:20

... at the P1 position and proline and glycine at the P2 and P3 positions [28]; neither of these residues, espe-cially proline, is preferred by other human cathepsins Previously, we have studied the ... distributed over the entire chimeric gene The DNA sequences of the parental sot gene and the trypsin gene (sprT) encoding SGT (in S griseus NBRC 13350) [21] are 82% identical Therefore, these genes ... mutants Unlike other mutants, the band at the molecular mass of SGT-L71P was hardly observed, but many other bands were seen In addition, the cul-ture supernatant had no activity In the case of inac-tive

Ngày tải lên: 16/03/2014, 00:20

... subtle, the phosphotyrosine at the +2 plays an impor-tant role in reordering the structure of the region of the C-terminal lobe that interacts with these substrates In the absence of the phosphate ... in the aF–aG loop in the C-terminal lobe, which has the effect of moving the loop residues Met828–Gln831 0.9 A˚ closer to the substrate There are, however, some conspicuous differences in the ... accomplished by the N-terminal lobe, espe-cially the b1–b2 loop (G loop) and aC regions Crys-tallization of the complex between the EphA3 kinase domain and the EPHOPT peptide did not result in the full

Ngày tải lên: 16/03/2014, 02:20

... targeted to the cell wall, where it is involved in the release of inorganic phosphate [20] The absence of a TatB component led to the idea that the TatAd protein may be bifunctional, fulfilling the roles ... the membrane if not exported (much of the membrane-bound GFP was incorrectly folded, suggesting a nonspecific interaction rather than a specific interaction with the translocon) Nevertheless, these ... and the mobilties of molecular mass markers (in kDa) are indicated on the left strates [8] Within the DmsA signal peptide we found that the twin arginine motif, the )1 serine residue and the

Ngày tải lên: 16/03/2014, 04:20

... attack of the a-phosphate of ATP Thus, according to the crystal structure, the spec-ificity of serine recognition depends on: (a) the zinc ion, (b) the size of the active site and (c) the hydrophilic ... characterize the other active site residues, which according to the crystal structure may influence the specificity of substrate recognition These are marked Trang 3with a black lozenge in Fig 1A The mutations ... brings the loop into the proximity of the zinc ion and enables direct contact between Gln400 and the carbonyl oxygen of the serine substrate [12] These movements are required to position the carboxylate

Ngày tải lên: 16/03/2014, 06:20

... shown in the crystal structure of rat MVK bound to ATP [17], depicted in Fig 9A, the active site of the enzyme is located at the interface of the N- and C-terminal domains of the monomer The adenosine ... bound to the 30S ribosome [33]. Trang 8nature is very similar to the functional flexibility ofsome of the amino acids identified at the active site of the cytosolic enzyme aconitase These data therefore ... when compared with wild-type MVK The data therefore indicate that the amino acids S146, E193, D204 and K13, present at the active site of the enzyme and required for the catalytic activity of MVK,

Ngày tải lên: 16/03/2014, 06:20

... forms the basis for the insect molecule on one side and the molecule from crabs on the other (Fig 3B) cDNA encoding the fibrinogen-like protein Sequence One species of insert was identified – the ... within the middle segment of the a-, b- and c-chains Hence, no further classification of the sponge protein to any of the three vertebrate chains can be made In the sponge sequence, besides the first ... are beneficial for the host However, the origin of most secondary metabolites identi-fied in sponges is not clear The understanding of the pathways which result in the synthesis of these compounds

Ngày tải lên: 16/03/2014, 16:20

... with the recognition site on the extracellular domain The second step will then be the deposition of the ligand into the TM pocket causing the conformation change of the receptor and triggering the ... monitoring the conformation movement and defining the final conformation of the eLPs These studies were limited to the three eLP domains The conformation of the eLPs in the simulated reduced form of the ... was then used to find the suitable fit of SQ29 548 in the ligand recognition pocket Figure 9 shows the relationship of the disulfide bond with ligand docking In the free form of the TP receptor, the

Ngày tải lên: 16/03/2014, 18:20

... frames Since the frame rate of the tracker is constant, these differences give us a measure of the instantaneous velocity of the object Due to inaccuracies in the tracking process, the raw data ... and the point density of the prototypes within the feature space will approximate the pdf of the feature vectors [6] The model is thus more accurate in areas of high probability density and so the ... vector space of the leaky neuron outputs, and thus model the pdf of these activations Further work is required to assess the distortion to the pdf of trajectories caused by representing the trajectories

Ngày tải lên: 16/03/2014, 19:20

... substrate, and the confirmation by site-directed mutagenesis ofthe involve-ment ofsome ofthese residues in the docking and catalysis ofcinnamic acid The impact ofthe active site mutations on the binding ... coli The inserts ofthe selected neosynthetized vectors were fully sequenced As neosynthetized DNA is not a template for the reaction, the amplification is linear, which is expected to keep the ... conserved atoms They were identified and added to the list ofthe block backbone conserved atoms These side chain atoms also provide the resulting rotamer value for the related target residue Other rotamers,

Ngày tải lên: 17/03/2014, 10:20

... website The final document was then submitted to NICE for publication on their website The other versions of the guideline (see below) were also discussed and approved by the GDG and published at the ... cancer, whether before chemotherapy or after neoadjuvant chemotherapy, the objective should be complete resection of all macroscopic disease • is available at the time they want it • includes the amount ... care for the population covered by this guideline The remit of the guideline Guideline topics selected by the DH identify the main areas to be covered by the guideline in a specific remit The following

Ngày tải lên: 22/03/2014, 16:21

... that the interaction with SNX9 is mediated by the proline-rich domain (PRD) of Itch, a domain distinct from the conven-tional WW recognition domain, and the SH3 domain of SNX9 Interaction with the ... the PRD of the related Ub ligase NEDD4 NEDD4 and Itch can inter-act with the same PY motif-containing substrate pro-tein, such as Melan-A [3], but the two ligases diverge in the sequence of their ... signalling [13] Binding of these two proteins to the PRD of NEDD4 has not been investi-gated, and it is therefore not known whether the inter-action can be mediated by either class I motif present

Ngày tải lên: 22/03/2014, 21:21

... and, other than the missing thioether bond, in the details of the heme attach-ment Notably, this similarity includes the stereochemistry of the covalent heme attachment to the protein The structure ... blue) Also shown are the heme ligands (histidine and methionine in each case), the cysteines that form thioether bonds to the heme, and the methyl group of the alanine of the C fasciculata AXXCH ... bonded to the N d atom of the heme axial histidine side chain; this interaction main-tains the correct orientation of the histidine ring to the heme iron. Trang 5of the alanine of the AXXCH motif

Ngày tải lên: 23/03/2014, 04:21

... the first experimental evidence to support the prediction resulting from the TP studies To fur-ther confirm the hypothesis, the active residues in the eLP2 segments must also be screened for other ... the N-terminus and the C-terminus of eLP2, which could then result in a conformational change of the ligand recognition site within the eLP2 region Another hypothesis is that the main chain distance ... 6Bb) shows the importance of the identity of the residue for ligand rec-ognition, and furthermore indicates that the residues Fig 7 The residues important for the ligand interaction in the eLP2

Ngày tải lên: 23/03/2014, 07:20

... NA2F These results together with thermodynamic binding data indicate that the complete oligosaccharide binding site of the lectin consists of five subsites allowing the specific recognition of the ... shown, together with the hydrogen bond network these waters make with the protein Superimposed in black are the equivalent residues of the mannose com-plex (subunit B in the asymmetric unit) The water ... and two with the 1–3 linked mannose (+2 subsite) (Fig 3B and Table 2) The mannose on the 1–6 arm occupies the monosaccharide binding site The GlcNAc residue on the 1–6 arm is bound in the )1 subsite

Ngày tải lên: 23/03/2014, 11:20