... Trang 3The objective of this study is to examine the level of national brand recognition of Qatar in the eyes of young FPT students The study aims to understand the perceptions and attitudes of these ... of the national brand recognition of Qatar in the eyes of young FPT students Trang 104 FINDINGThe research findings are the results obtained from the analysis of the data collected during the ... understanding of the national brand By gaining insight into the national brand recognition of Qatar in the eyes of young FPT students, the study aims to contribute to the development of a more effective
Ngày tải lên: 12/05/2024, 21:58
... built-up zone expansion The presentation of the results is mainly based on cartography of the factor scores produced as a result of the application of the PCA on the dataset 2 Methodology ... put on the comprehensibility of the factors In other words, the components kept were to those whose dimension of meaning was readily comprehensible in the scope of the research Finally the factor ... relatively The first component provides 53.8% of the variance of the dataset while the second component takes 33.9% of the variance, Hence, those two first components represent almost 88% of the
Ngày tải lên: 13/02/2014, 12:20
Báo cáo khoa học: Differential recognition of heat shock elements by members of the heat shock transcription factor family ppt
... promoters These results show that the configuration of nGAAn units in the promoter is important in determining which hHSF members are involved in the regulation of the gene Footprint analysis of the ... hHSF4–VP16, without changing the magnitude of the heat shock response (cp3) The mutational analysis of the CRYGA and CRYGC HSEs suggests that the nucleotide sequences and configuration of nGAAn-like units ... expression of the luciferase gene dri-ven by promoters of the human c-crystallin genes, whose mouse orthologs are transcriptionally regulated by HSF1 and HSF4 [21,22] As shown in Fig 5A, the HSE of the
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Conserved residues in the N-domain of the AAA+ chaperone ClpA regulate substrate recognition and unfolding pdf
... ClpA, one in the N-domain and the other in the pore of the ClpA hexamer In the case of short unstructured peptides or unfolded proteins such as casein, binding to the tyrosine residues in the hexamer-ic ... utilizes the energy of ATP to control substrate recognition and unfolding The precise role of the N-domains of ClpA in this process, however, remains elusive Here, we have analysed the role of five ... to specific recognition of substrates such as SsrA-tagged proteins In order to further study the role of the N-domains in substrate recognition, we compared the amino acid sequences of this region
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Relation between domain evolution, specificity, and taxonomy of the a-amylase family members containing a C-terminal starch-binding domain pot
... to each other and close to the border that separates the two major parts of the tree Note that the B stearothermophilus maltogenic a-amylase (Bacst) is placed in the ÔCGTase groupÕ of the tree ... between the hydrolases and transglycosi-dases, but rather there may be one between the compact cluster of Bacillus and Thermoanaerobacter CGTases and the remaining enzymes The positions of the two ... illustrating the arrangement of all domains in the five-domain members of the GH 13, can be taken as an approximation of the first three domains in the four-domain members It also shows the typical
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt
... structures of the b-amino acids that best fit are shown in Fig 6 They all correspond to gauche(+) values of the h angle The methyl group of b2-HAla occupies a position close to that of CHb of Pro or the ... may keep the molecular recognition properties of a-peptides and the biological stability of b-peptides Only a few data have been reported in the literature on the structural properties of these ... Conversely, the methyl group of b3-HAla occupies a position similar to the pro R methyl of Aib, on the opposite side of the pyrrolidine ring of Pro A parallel can be drawn regarding the differences
Ngày tải lên: 08/03/2014, 08:20
Báo cáo Y học: Properties of group I allergens from grass pollen and their relation to cathepsin B, a member of the C1 family of cysteine proteinases pdf
... parasites of the genus Giardia are one of the earliest lineages of eukaryotic cells, and the Giardia protease is the earliest known branch of the cathepsin B family [23] Its phylogeny confirms that the ... concentra-ting the allergen according to the isoelectric point (pI) of the molecule A pH gradient from 2 to 11 was established for the characterization of Phl p 1 After completion of the run, the individual ... that the conserved His104 residue is involved in the catalytic activity of b-expansins These results indicate a common origin of cathepsin B and b-expansins, especially if taken together with their
Ngày tải lên: 08/03/2014, 22:20
Báo cáo khoa học: Cross-species divergence of the major recognition pathways of ubiquitylated substrates for ubiquitin⁄26S proteasome-mediated proteolysis potx
... RPN13 The potential involvement of the hydrophobicpatch in the UBL of hHR23b was also examined TheUBL variants constructed for analysis of the associa-tion of RPN10 with human hHR23b and the DSK2homologs ... which each of the UBAs of Arabdopsis RAD23 contributes additively to the binding of K48-linked ubiquitin chains (Table 1 and data not shown) The roles of the UBAs in ubiquitin chain binding of human ... divergence of proteasomal recognition of the RAD23 and DSK2 homologs by RPN10With respect to the indirect recognition of ubiquity-lated substrates by UBL–UBA factors, it is notknown whether the same
Ngày tải lên: 15/03/2014, 09:20
Báo cáo khoa học: Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases pot
... subtle, the phosphotyrosine at the +2 plays an impor-tant role in reordering the structure of the region of the C-terminal lobe that interacts with these substrates In the absence of the phosphate ... and Glu+1 with those of EPHOPT in (B). Table 2 Kinetic data The upper panel shows the effect of varying amino acids at the +2 position of the substrate The sequences of the tested peptides are ... flexibility of these two regions, several other kinase resi-dues within 4 A ˚ of the EPHOPT substrate are also shown These residues are clearly fixed in their orientation regardless of whether substrate
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: Structural flexibility of the methanogenic-type seryl-tRNA synthetase active site and its implication for specific substrate recognition pptx
... attack of the a-phosphate of ATP Thus, according to the crystal structure, the spec-ificity of serine recognition depends on: (a) the zinc ion, (b) the size of the active site and (c) the hydrophilic ... Model of the acceptor end of tRNASerbound in the active site of mMbSerRS The view is focused on the acceptor part of tRNA in the active site of mMbSerRS The tRNA is shown as an orange tube with the ... positioned above the catalytic core of the other Interestingly, Arg267 from the beginning of helix 9 in the HTH fold of one monomer is positioned towards the active site of the other monomer and
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Regulation of luteinizing hormone receptor mRNA expression by mevalonate kinase – role of the catalytic center in mRNA recognition potx
... at the interface of the N- and C-terminal domains of the monomer The adenosine base of ATP is bound at the base of the left-handed b–a–b fold, where it interacts with a num-ber of residues in the ... the mutation of any of the four amino acids at the active site of MVK decreases its binding to LHR mRNA, we examined whether these mutants were able to reverse the inhibitory effect of wild-type ... system in the pres-ence or abspres-ence of the MVK mutant proteins The results showed that mutations of the active site residues of MVK abrogated the inhibitory effect on LHR mRNA translation Therefore,
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: NMR structure of the thromboxane A2 receptor ligand recognition pocket pot
... [1] Mutation of the conserved sequence WCF in eLP2of the EP receptor has been reported to change the ligand binding recognition of the receptor [30] The relationship of the changes of the conserved ... 2impaired further definition of the ligand recognitionpocket on the extracellular side of the receptors This has become a major obstacle to the further understanding of the molecular mechanism of the specific ... in the ligand recognition pocket Figure 9 shows the relationship of the disulfide bond with ligand docking In the free form of the TP receptor, the exposed disulfide bond on the surface of the
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: A profile of the residues in the second extracellular loop that are critical for ligand recognition of human prostacyclin receptor pdf
... another Cys in eLP1 However, the nature of the conservation in the eLP2 region between TP and IP has led to the prediction that the residues in the segment are involved in the configuration of ... either a cis or a trans confor-mation, is a critical residue for the configuration of the secondary structure of the protein The replacement of P179 with Ala could alter the distance between the ... the N-terminus and the C-terminus of eLP2, which could then result in a conformational change of the ligand recognition site within the eLP2 region Another hypothesis is that the main chain distance
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin ppt
... is the corresponding orientation of the side chain of Glu221 The second conformation of the side chain of Glu221, which also adopts two conformations but not correlated with the anomeric form of ... a-configuration in the binding site of subunit A, but adopts an a⁄ b mix-ture in the binding site of subunit B Accommodation of the b-configuration in the binding site of PAL requires a change in the rotamer ... series of smaller oligosaccha-ride constituents of NA2F These results together with thermodynamic binding data indicate that the complete oligosaccharide binding site of the lectin consists of five
Ngày tải lên: 23/03/2014, 11:20
Báo cáo khoa học: Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase pptx
... in light of the steady-state kinetics, stability and structural data presented The finding of the present study demonstrate that the gating segment of the substrate-recognition loop is of particular ... mutagenesis in the vicinity of the FAD-binding pocket, the mutants remain properly fla-vinylated (not shown) The thermal stability was inves-tigated using the ThermoFAD technique to derive thermal unfolding ... Comparison of the active-site volumes To determine whether there are changes in the volume of the active site as a result of mutations that may explain the ability to accommodate substrates other than
Ngày tải lên: 29/03/2014, 09:20
Guattari’s Aesthetic Paradigm: From the Folding of the Finite/Infinite Relation to Schizoanalytic Metamodelisation docx
... of the present Although specific instances of contemporary artmight then be part of the aesthetic paradigm, the notion of art in generalcan stymie access to the latter in that it reduces aesthetic ... onto thereterritorialisation of the movement of infinity in finite modes The general(and relative) aestheticisation of the diverse Universes of value leads to adifferent type of re-enchantment of ... in the second, here there is the instalment of local coding or singular points of organisation. We might usefully turn to the late writings of Foucault at this pointand insert the diagram of ‘the
Ngày tải lên: 30/03/2014, 11:20
state of the art in face recognition
... set of data, M={ , ,x11"x1n1, , , ,"xij"xCn C}, where xij is the jth training sample of the ith class, and n i is the number of samples of the ith class, C is the number of classes The ... between the previous face recognition research state and the future state Also, the purpose of the book is to present the reader with cutting edge research on the face recognition field Besides, the ... 2007) we introduced the concepts of dissimilarity-based face recognition and their relationship with the nearest feature classifiers For convenience of the reader and for the sake of self–containedness,
Ngày tải lên: 28/04/2014, 09:59
báo cáo hóa học: " The assessment of health-related quality of life in relation to the body mass index value in the urban population of Belgrade" potx
... of the general quality of life [8-11] Whilst obesity has an obvious and often objectively measurable impact on the state of health of the individual, the influence of increased body weight on the ... The assessment of health-related quality of life in relation to the body mass index value in the urban population of Belgrade Address: 1 Institute of Hygiene and Medical Ecology Department of ... other instruments to assess HRQL [36] Our conclusions that increased values of BMI affect the quality of life, and particularly the physical health of the individual, coincide with those of other
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:"The role of disclosure in relation to assent to participate in HIV-related research among HIV-infected youth: a formative study" docx
... but sometime during the course of the research or at the end of the research Some health professionals also commented that the timing of disclo-sure depended on the type of study: According to ... told at the beginning of the research Their rea-sons focused on reducing the children being taken aback upon learning their status during the course of the research and for enhancing the children's ... for them to know it in advance, before their participation in the research study They must also know the reasons of their participation in the research study – what they will talk about in the
Ngày tải lên: 20/06/2014, 08:20
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