interaction between ca 2 regulated kinases and proteases
Tài liệu Báo cáo khoa học: Functional interaction between RNA helicase II⁄Gua and ribosomal protein L4 pptx
... si-L4-M1 2 nd transfection 18S 28S 18S 28S 32S 47S/45S 54 ±5 84±1084 ±10 73±683 ±5 42±747 ±6 100 Total±SE WB: anti-HA 204 264 428 428 333 264 333 ∆264-333 ∆264-333 ∆204-264 ∆264-333 FLAG-∆204-264 ... M1 M2 M3 M4 M5 M6 264 333 428 131 131 131 196 264 333 264 204 204 264 – – + – + + Nucleoplasm and cytoplasm Nucleoli Nucleoli Nucleoplasm and cytoplasm Nucleoplasm Nucleoplasm 333 333 428 428 ... acids 264–333 seems to be the RPL4-Gua-interacting domain, the D204-264 mutant, A D Human 1120 Mouse 1129 mRPL4 mU1C si-L4-M1 47S/45S 32S 28S 18S 18S 28S RT-PCR Western hU1C hRPL4 hRPL4 hB23 Fig...
Ngày tải lên: 20/02/2014, 01:20
Báo cáo khoa học: Structural basis for the interaction between dynein light chain 1 and the glutamate channel homolog GRINL1A docx
... are: I423 with V66, L84 and F73, V425 with F62, F73, Y75 and L84, and C427 with G63, Y75, Y77 and A82 The latter are also pres-ent in the nNOS–DYNLL1 complex for the equivalpres-ent I233 and V235 ... salt-bridge interactions are found between the carboxylate group of E422 and the amine groups of K43 and K44 of monomer B, and the side chains of R421 and D12 of monomer A These residues point ... Ciencia e Innovacio´n BFU2009-10442, CTQ2008-00080⁄ BQU and CSD2006-00023 We would like to thank Fernando Roncal (CBM, Madrid) for synthesis of the pepscan cellulose membranes and Peter Rapali (Budapest,...
Ngày tải lên: 29/03/2014, 09:20
Báo cáo khoa học:" The interaction between the measles virus nucleoprotein and the Interferon Regulator Factor 3 relies on a specific cellular environment" pdf
... line) is typical of a structured protein with a predominant α-helical content, as indicated by the positive ellipticity between 185 and 200 nm, and by the two minima at 208 and 222 nm The calculated ... method and the RT-PCR were performed as described elsewhere [36] The IFR-3 cDNA was PCR amplified using forward 5'-CATGAATTCATGGGAACCCCAAAGCCA-3' and backward 5'-TGACTCGAGTCAGCTCTCCCCAG-GGCC-3' ... IRF-3 RD, was stored at -20°C Purification of histidine-tagged N, XD and of wt or cys-substituted NTAIL proteins was carried out as described in [2,26,29,30,38] All purification steps, except for...
Ngày tải lên: 12/08/2014, 04:21
Báo cáo y học: "Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione s-transferase in a cross-sectional study" ppt
... to 2.52) 0.227 67 0.72 (0.42 to 1.22) 0.223 Null/Never 72 1.35 (0.65 to 2.79) 0.421 67 0.75 (0.42 to 1.36) 0.349 Null/Ever 81 2.01 (1.13 to 3.55) 0.017 70 0.83 (0.49 to 1.42) 0.502 AP = 0.12 (-1.41 ... SONORA (OR, 21.04; 95% CI, 4.82 to 91.75) (Figure 2) GSTM1-smoking and SE-smoking interactions There were no significant additive or multiplicative interactions between GSTM1 status and smoking ... SE-positive (one allele) 79 3.23 (2.17 to 4.81) < 0.001 68 1.77 (1.21 to 2.60) 0.003 SE-positive (two alleles) 93 10.65 (5.61 to 20.20) < 0.001 92 10.27 (5.05 to 20.89) < 0.001 a ACPA, anticitrullinated...
Ngày tải lên: 12/08/2014, 15:22
Interaction between a spoolable complliant guide and coiled tubing during subsea well intervention in deep water
... Coiled Tubing (Inner Pipe) 24 3.1.3 Material 25 4 Physical Model Tests 26 4.1 Aim of Model Tests 26 4.2 Model Test Scaling 27 4.2.1 Scaling of Pipe in Pipe Model 28 Trang 44.3 Test Phases ... Schlumberger) 23 Figure 3.2: possible vessel positions and SCG shapes during operation (courtesy of Schlumberger) 24 Figure 4.1: Mechanical interaction between SCG and CT 27 Figure 4.2: 60° inclined 25.4 ... result in chapter 7 and those by Kuroiwa et al (2002) Figure 2.1: Local moment and local effective tension for real scale pipe-in-pipe analysis (Schlumberger, 2009) The local moment was determined...
Ngày tải lên: 16/10/2015, 15:35
On the interaction between the crude oil market and the macroeconomic activity: How do the 2000s differ from the 70s?
... 4.240093 14.55421 3.201455 4.263888 Minimum -31.09554 -40.35870 -0.313903 -4.889300 -19.84509 Maximum 45.89497 31.73241 0.258876 5.501214 23.92297 J-B 70.58925 25.55148 1537.706 0.442872 62.41340 ... processes for US CO prices and 0.047190 (16.70316) -2.903846 (-6.47562) 0.060134 (0.145233) C 54.12766 (7.583166) 88.11260 (12.72525) 2.76E-05 (1.072516) 0.828139 (3.444510) 45.12262 (10.00961) (-14.9117) ... (-3.40727) -0.008223 (-0.01653) Θ1 0.273428 (4.168602) 0.109098 (1.520407) 0.389917 (6.145377) -0.209481 (-0.33416) (-3.41680) -0.132457 (-0.25198) GARCH in mean 2.735749 (6.923142) α1 0.321111...
Ngày tải lên: 01/02/2020, 21:44
Numerical and experimental modeling of interaction between a turbulent jet flow and an inlet
... -G1A22 85 = 4A41As1x 2A41As2 + A42As1 S 7 -_ S2A11As1x 2 G1 (2A41As2 + A42Asi) G1A22As2 8 9 = -2A11A21As1x4 82 = E1 (1 + k2xm) 8 _ A21A11x 2 4 -G1A22 Table 2 AuA43A51x 2 Sa= ... + 2A33) Sl8 = A32S1 S20 = -2A32S6 S22 = 2Sl S4(l + S 4) S24 = SJ S12 + 2S3S4S15 + S3S19 S26 = S;f S20 - S2SJ S2s=fi(k1xn) Au A22G1 S3 0 = SiS11 + S§S13 + S§S12 S32 = S11S22 + s§ S21 ... S19 = A32S6 S21 = A32S6 S23 = 2S3S4S12 + S§S1s +S4S14 +Sis S25 = S4(S4S15 + S19) S29 = - S2S§ S31 = s;; sl6 - 2s2S3S4 3 Results S12 = 3A31Ssx 2 S14 = 3A31 S1Sgx 2 Sl6 = - x 2 (6A31S6Sg...
Ngày tải lên: 10/02/2020, 01:36
Study on the interaction between the buffer zone community and biodiversity conservation in xuan son national park, phutho province
... 2.2.1.1 Khai thác gỗ trái phép 58 2.2.1.2 Gỗ củi 59 2.2.1.3 Săn bắn thu hái lâm sản gỗ 60 2.2.1.4 Canh tác nương rẫy, mở rộng diện tích đất nơng nghiệp 62 2.2.1.5 ... 20 2.3.1.2 Tình hình Việt Nam 22 2.3.2 Các nghiên cứu VQG Xuân Sơn 24 Mục tiêu câu hỏi nghiên cứu 25 3.1 Mục tiêu tổng quát 25 3.2 Mục tiêu ... 62 2.2.1.5 Chăn thả gia súc 63 2.2.2 Nguyên nhân gián tiếp (nguyên nhân sâu xa) 63 2.2.2.1 Tăng dân số 64 2.2.2.2 Đói nghèo 65 CHƢƠNG 3: TÁC ĐỘNG...
Ngày tải lên: 25/03/2020, 23:12
market driven challenges to freedom of expression and the interaction between the state the market and the media
... Media LandscapeChallenges to Financing Journalism Advertising has for a long time been a major income source for the press and the com-mercial broadcast media Changes in the media landscape have ... (Sundin, 2013; Ohls-son, 2015a) The market share for the Swedish daily press has declined from 82 per cent in 1989 to 45 per cent in 2013 (Ohlsson & Truedsson, 2015: 9-10) Google and Facebook ... state and commercial interests and to provide for control of the state (and other power subjects) and to provide for pluralism in both providers and content Freedom of expression in Sweden is regulated...
Ngày tải lên: 04/12/2022, 15:15
Luận văn study on the interaction between the buffer zone community and biodiversity conservation in xuan son national park phutho province
... nghiệp 29.42 87,16 il | Đất sản xuất nông nghiệp 2.018.63 5,98 Dail trắng cây hàng năm 1072 3.18 = Dal trắng lúa 99 294 Đất trồng cây lầu năm 946.56 2,80 1⁄2 | Đấtlâm nghiệp 27.362.56 81,04 ... Sơn 685 659 503| 156 - - 96,2 Tan Son 835 834 834 - - - 99,9 Xuân Dai 1.299 1153| 1102 31 - - 88,8 Minh Dai 1.470 834 532 3 - - 56,7 Xuân Sơn 249 245 116| 127 - 2 98,4 Kim Thượng | 1351 L31[ ... Học Ila NGi - 2011 Trang 3215 _ Công dng 15 17 2.2.2 Tình hình bão tổn DDSIHT tại Việt Nam - 19 23 ‘Vinng đệm và vùng lôi trong các khu bão tôn và vườn quốc gia "1 2.3.1 Nghiên cứu...
Ngày tải lên: 17/05/2025, 20:46
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... CD2-1-7 CD2-1-8 CD2-1 PD 250 Input GST CD2-1-1 CD2-1-2 CD2-1-3 CD2-1-4 CD2-1 PD 250 150 MAP2 MBD RII CD1 CD2 CD3 1–147 148–599 600–1099 1100–1518 1519–1829 767 934 CD2-1 CD2-2 CD2-3 600 CD2 Inter-action ... -MAP2 GST RII CD1 CD2 CD3 MBD IB: -v-KIND 250 150 IB: -v-KIND Input GST CD2-1 CD2-2 CD2-3 CD2 PD 250 150 Input GST CD2-1-6-1 CD2-1-6-2 CD2-1-6-3 CD2-1 PD IB: -v-KIND 250 150 Input GST CD2-1-5 CD2-1-6 ... CD2 region of MAP2 specifi-cally binds to KIND2 in v-KIND, we screened the v-KIND ΔKIND1 ΔKIND2 ΔKIND1+2 ΔRasN ΔGEF KIND1 KIND2 KIND1 KIND2 CC RasN GEF 1 37–217 456–620 1238–1364 1461–1734 1742...
Ngày tải lên: 14/02/2014, 19:20
Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2 pot
... GST–SAFB2C (µg) FLAG–SRPK1a R 0 GST–SAFB2C 1 2 3 4 1 2 3 4 FLAG–SRPK1a GST–NtLBR GST–SAFB2C (µg) 66- 45- 35- 25- 116- 66- 45- 35- 25-1 2 2 Fig 2 Effect of GST–SAFB1CDRE and GST–SAFB2C on FLAG–SRPK1a ... MINT-7228149 : SRPK1 (uniprotkb: Q96SB4-2 ) phosphorylates ( MI:0217 ) Nt-LBR (uni-protkb: Q14739 ) by protein kinase assay ( MI:0424 ) l MINT-7228207 : SRPK1 (uniprotkb: Q96SB4-2 ) physically ... + + 0 7.5 22.5 37.5 + + + + + + + + 0 7.5 22.5 37.5 GST–NtLBR GST–NtLBR GST–SAFB1C ΔRE FLAG–SRPK1a GST–NtLBR GST–SAFB2C FLAG–SRPK1a GST–P2P-R GST–SAFB2C FLAG–SRPK1a GST–P2P-R GST–SAFB2C (µg) FLAG–SRPK1a...
Ngày tải lên: 30/03/2014, 01:20
linear entropy and squeezing of the interaction between two quantum system described by su 1 1 and su 2 lie group in presence of two external terms
... equations d2Rˆz dt2 + 4 ˆC2Rˆz = 4 ˆC2N − ∆ ˆˆ C, d 2Sˆz dt2 + 4 ˆC2Sˆz = 2∆ ˆC. (22) Also we have d2Sˆ+ dt2 −2iΩz + ˆCd ˆS+ dt − " 2λ2 N −ˆ 1 2 ! + 2Ωz Cˆ +Ωz 2 ! # ˆ S+= 0, (23) and d2Sˆ− dt2 ... 2i Ωz− ˆCd ˆS− dt + " 2λ2 Nˆ +1 2 ! + 2Ωz C −ˆ Ωz 2 ! # ˆ S−= 0 (24) Furthermore d2Rˆ+ dt2 −2iΩz + ˆC d ˆR+ dt − " 2λ2 N −ˆ 1 2 ! + 2Ωz Cˆ+Ωz 2 ! # ˆ R+= 0, (25) finally d2Rˆ− dt2 ... cos2η − sin2η 1 2sin 2η −sin2η cos2η 1 2sin 2η −sin 2η − sin 2η cos 2η + / -* , ˆ S+ ˆ S− ˆ S z + / here we take ϑ =1 2tanh −1 2λ1 ω ! , η =1 2tan −1 2λ2 ω ! Trang 5From eqs (15) and (16) taking...
Ngày tải lên: 04/12/2022, 15:02
Tài liệu Báo cáo khoa học: Paradoxical interactions between modifiers and elastase-2 Patricia Schenker and Antonio Baici docx
... l M MU 142.5 ± 9.2 1.62 PPS, 5.6 m M MU 37.7 ± 1.2 0.43 DS, 0.1 m M DU 229.9 ± 14.5 2.90 DS, 10.0 m M DU 112.0 ± 12.4 1.41 Ch6S, 0.2 l M DU 147.8 ± 9.7 1.41 Ch6S, 200 l M DU 94.6 ± 23.2 0.91 Trang ... G: physicochemical properties, activity and physiopathological functions Biochimie 90, 227–242 4 Baici A & Bradamante P (1984) Interaction between human leukocyte elastase and chondroitin ... Zurich, Switzerland Fax: +41 44 6356805 Tel: +41 44 6355542 E-mail: abaici@bioc.uzh.ch (Received 4 December 2009, revised 23 March 2010, accepted 25 March 2010) doi:10.1111/j.1742-4658.2010.07663.x...
Ngày tải lên: 16/02/2014, 14:20
Báo cáo khoa học: Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1 – a molecular link between recombination and chromatin assembly during meiosis pot
... amplification TGTCGGGAGCAGATTCA; 381R, 5¢-TGCTACTTCTC TCAGCGGCCGCATTCTTAT CcCac1L-C: 382F, 5¢-CA 5¢-GAGATTTCAGTTTCGTCACTCGAGCGG To over-express N-terminal hexahistidine-tagged CcCac1L-N (His-CcCac1L-N) ... results suggest that the interaction between CcLim15 and CcCac1L is related to specific events during the mei-otic prophase Interaction between CcCac1L and CcPCNA during meiosis CAF-1 forms a complex ... January 2008, revised 24 February 2008, accepted 25 February 2008) doi:10.1111/j.1742-4658.2008.06357.x In eukaryotes, meiosis leads to genetically variable gametes through recom-bination between...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
... protein tyrosine kinases [11] and a Ca2þ-dependent endonuclease [12] Many of these processes/enzymes are also known to be regulated by Ca2þ Cytosolic free Ca2þ concentration ([Ca2þ]cyt) is tightly ... 14.2) (1.9 – 3.6) (1.3 – 2.5) (0.24 – 0.42) (11.9 – 12.2) (4.9 – 8.0) (1.8 – 2.4) (0.23 – 0.41) (4.7 – 5.2) Trang 6addition of Ca2þ shifts it to an E1 conformation (lowfluorescence state) [28,30] ... SERCA 1; cardiac SR (Figs 1C,D) express predominantly SERCA 2a; cerebellar microsomes (Fig 1E,F) express mostly SERCA 2b and platelet microsomes (Fig 1G,H) express a mixture of SERCA 2b and SERCA...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo khóa học: Phospholipase C, protein kinase C, Ca 2+ /calmodulin-dependent protein kinase II, and redox state are involved in epigallocatechin gallate-induced phospholipase D activation in human astroglioma cells ppt
... min, and [Ca2+] i was measured (B) After the removal of extracellular Ca 2+ (0 Ca 2+ ), the quiescent cells were treated with EGCG for 3 min, and then [Ca2+] i was measured Measurements of [Ca2+] ... Fax: +82 51 513 9258, Tel.: +82 51 510 1775 (from 1 September 2004). Abbreviations: CaM kinase II, Ca2+/calmodulin-dependent protein kinase II; DCFH, dichlorofluorescein diacetate; DCF, 2¢,7¢-dichlorofluorescein; ... ROS cascade induced by EGCG EGCG increased [Ca2+]iin U87 cells, and chelation of [Ca2+]i by BAPTA/AM abolished EGCG-induced PLD activation It is therefore assumed that the increase in [Ca2+]imay...
Ngày tải lên: 16/03/2014, 16:20
Báo cáo Y học: Amino acids 3–13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf
... 36antisense, pr17–32sense, pr17–32antisense, pr24–39sense, and pr24–39antisense Primers pr18/19AA, pr20/21AA, pr22A, pr24/25AA, pr26/27AA, pr28/29AA, and pr30/ 31AA sense and antisense oligonucleotides ... pGalAD-AR17)32(18/19AA), pGalAD-AR17)32(20/21AA), pGalAD-AR17)32(23 A), pGalAD-AR17)32(24/25AA), pGalAD-AR17)32(26/27AA), pGalAD-AR17)32(28/29AA) and pGalAD-AR17)32(30/31AA) Oligonucleotides for these AR peptide ... acids 23, 26 and 27 completely abolished interaction with GalDBD-AR.LBD and alanines at posi-tions 24 and 25 increased the interaction capacity All alanine substitutions of amino acids flanking23FQNLF27...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo khoa học: The starch-binding capacity of the noncatalytic SBD2 region and the interaction between the N- and C-terminal domains are involved in the modulation of the activity of starch synthase III fromArabidopsis thaliana pdf
... CD+D123 75 50 30 15 CD A B D123 D23 D1 St2.1 St3.3 St2.2 St3.2 St2.3 D2 D3 Fig 4 SDS-PAGE analysis of co-expressed SBD proteins plus CD: D123, D23, D1, St2.1, St3.3, St2.2, St3.2, St2.3, D2 and ... CD + D2 CD + D1 CD + St2.1 CD + St2.2 CD + St2.3 CD + St3.3 CD + St3.2 D1 xD2 D3 CD CD-D123W366A W366A D1 D2 D3 CD CD-D123Y394A D1 D2 D3 CD CD-D123W366AY394A Y394A x x x W366A Y394A 1025 22 316 ... CD-D123 4.08 ± 0.49 1.1 ± 0.3 5.53 ± 0.52 CD 0.28 ± 0.05 1.0 ± 0.2 0.06 ± 0.01 CD+D123 0.95 ± 0.18 1.1 ± 0.2 0.60 ± 0.14 CD–D23 2.56 ± 0.54 2.0 ± 0.5 5.26 ± 0.48 CD–St2.1 2.39 ± 0.17 1.8 ± 0.2 4.95...
Ngày tải lên: 22/03/2014, 21:20
Báo cáo khoa học: The interaction between casein kinase Ia and 14-3-3 is phosphorylation dependent pot
... of both residues 218 and 242 Figure 8 shows that the S218A mutation caused a significant reduction in 14-3-3g binding compared to wild-type CKIa, whereas S242A and double S218⁄ 242A mutation reduced ... homologues (BMH1 and BMH2) GST σσ 1% lysate GST 14-3-3 32.5 47.5 25 62.5 83 175 Western blot 25 16 47.5 62.5 83 175 GST GST-14-3-3 kDa Ponceau S 32.5 25 16 GST 0 20 40 60 80 100 120 β γ ζ η σ τ ... 32.5 25 32.5 47.5 1% of lysate 32.5 47.5 14-3-3η IgG IgG 25 16 62.5 DNA A B C Fig 8 Residues Ser218 and Ser242 of CKIa are required for 14-3-3 association (A) Transfected HEK2914-3-3...
Ngày tải lên: 23/03/2014, 04:20