2 transients mediated by ryrs see note 2
Báo cáo y học: "Homocysteine-induced macrophage inflammatory protein-2 production by glomerular mesangial cells is mediated by PI3 Kinase and p38 MAPK" doc
... Hcy-induced MIP -2 was significantly attenuated (p < 0.05) by a PI-3 Kinase inhibitor (LY2940 02) and by an inhibitor of a p38MAPK (SB203580) In contrast, use of a p 42/ 44 MAPK inhibitor (U0 126 ) did not ... Hcy + LY2940 02 Hcy + SB203580 Figure Homocysteine-induced MIP- is mediated by p38MAPK and PI3 kinase Homocysteine-induced MIP- is mediated by p38MAPK and PI3 kinase MCs were incubated (24 hours; ... Hcy-induced MIP -2 in MC Indeed, we observed that Hcy-induced MIP -2 expression was inhibited by PI-3 kinase inhibitor (LY2940 02) and p38MAPK inhibitor (SB203580), but was unaffected by p 42/ 44 MAPK inhibitor...
Ngày tải lên: 11/08/2014, 08:22
Electronic communications mediated by metal clusters and pi conjugated systems 2
... Cu(1)-Cu(3)-Cu (2) 59.13 (2) Cu(1)-P(1) 2. 291 (2) Cu(1)-C(1)-Cu (2) 74.8 (2) Cu (2) -P(3) 2. 2861 (2) Cu(1)-C(1)-Cu(3) 69.1 (2) Cu(3)-P(5) 2. 2 828 (2) Cu (2) -C(1)-Cu(3) 72. 9 (2) Cu(1)-C(1) 2. 184(5) Cu(1)-C(3)-Cu (2) 70.8 (2) ... 28 26 24 22 20 18 16 14 12 10 -2 -4 -6 -8 -10 - 12 -14 -16 -18 -20 -22 -24 -26 -28 (ppm) 60 50 40 30 20 10 -10 -20 -30 -40 -50 -60 -70 -80 -90 -100 -110 - 120 -130 -140 -154.5114 -148.7 028 -1 42. 8943 ... 80 23 26 b -47±10 43±10 90±10 35 27 b -29 7±10 -77±10 22 0±10 6100 25 00 27 a-c -330 -45 28 5 1 .2 105 27 f (C≡CFc )2} Trans-[Pt(PMePh2 )2 (C≡CFc )2] trans-[Ru(PBu3 )2( CO )2 (C≡CFc )2] trans- 70 [Ru(dppm )2( C≡CFc )2] ...
Ngày tải lên: 17/09/2015, 17:17
Tài liệu Báo cáo khoa học: 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-c-dependent and mediated by the caspase-3-dependent apoptotic pathway doc
... TZDs in 3T3-L1 adipocyte 19 20 21 22 23 24 25 26 27 28 29 30 31 32 agonist improve insulin resistance J Biol Chem 27 6, 4 124 5–4 125 4 Berger J & Moller DE (20 02) The mechanisms of action of PPARs ... acid, pH 7.8, 1 92 mm Na2HPO4) for h, treated with RNase (20 0 lgÆmL)1) for h, stained with 30 lgÆmL)1 PI in FEBS Journal 27 7 (20 10) 687–696 ª 20 09 The Authors Journal compilation ª 20 09 FEBS Y Xiao ... Apoptosis 12, 1953–1963 15 Yang JY, Della-Fera MA & Baile CA (20 08) Guggulsterone inhibits adipocyte differentiation and induces apoptosis in 3T3-L1 cells Obesity 16, 16 22 , doi:10.1038/oby .20 07 .24 16...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases pptx
... 1670 596 16 .2 1 .24 0.51 0.09 8.4 4.8 5.3 7.4 2. 0 7.9 · · · · · · 107 108 109 109 1010 1010 Recovery (%) Purification (fold) 100 20 5 61 6.8 7 .2 5 .2 5.7 62. 7 88.8 23 7 939 FEBS Journal 27 5 (20 08) 3099–3109 ... was supported by The Institute of Cancer Research, Cancer Research UK (CUK) grant numbers C309 ⁄ 21 87 and C309 ⁄ A 827 4 and by AICR grant 02- 1 12 FEBS Journal 27 5 (20 08) 3099–3109 ª 20 08 The Institute ... RW & Hengst L (20 07) Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases Cell 128 , 26 9 28 0 FEBS Journal 27 5 (20 08) 3099–3109 ª 20 08 The Institute...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: Staphylococcal enterotoxin C1-induced pyrogenic cytokine production in human peripheral blood mononuclear cells is mediated by NADPH oxidase and nuclear factor-kappa B doc
... + Apo 12 2141 13 176 12 92 27 1900 22 1931 16 1981 25 20 57 32 IL-6 ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± 5* 62 7 179 155 25 2 22 3 2 160 325 00 100 5500 27 1 6800 330 3 720 0 20 0 39500 403 34400 28 3 38700 ... ± ± ± 510* 21 0 100 26 0 90 960 26 870 93 860 100 870 2 0.18 1.06 0 .21 0. 32 0.11 0.31 0 .22 1.19 0.13 1. 12 0.11 1.07 0 .22 1.08 0 .21 0 .25 ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± 0. 02 0.03 0. 02 0.04 0.06 ... tested IL-6 ± ± ± ± ± ± ± ± ± ± ± ± 52* 71* 49* 95* 75* 60* 90 5000 100 26 200 1 02 33600 82 48300 110 70000 108 6 420 0 ± ± ± ± ± ± ± ± ± ± ± ± 100* 12 200* 21 0* 320 * 12 440* 10 360* also inhibited the...
Ngày tải lên: 19/02/2014, 00:20
Tài liệu Báo cáo khoa học: Aggregative organization enhances the DNA end-joining process that is mediated by DNA-dependent protein kinase pdf
... DNA ligase ATP Multimer DimerTrimer Monomer 10 11 12 13 14 15 Mono Q fraction Multimer DimerTrimer Monomer 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 Fig End-joining activity is associated with ... Biochemistry 26 , 6387–63 92 Tsang SS, Chow SA & Radding CM (1985) Networks of DNA and RecA protein are intermediates in homologous pairing Biochemistry 24 , 322 6– 323 2 FEBS Journal 27 3 (20 06) 3063–3075 ª 20 06 ... Griffith JD & Chu G (20 02) Synapsis of DNA ends by DNA-dependent protein kinase EMBO J 21 , 31 92 320 0 45 Chan DW, Chen BP, Prithivirajsingh S, Kurimasa A, Story MD, Qin J & Chen DJ (20 02) Autophosphorylation...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Evidence for proteasome dysfunction in cytotoxicity mediated by anti-Ras intracellular antibodies pdf
... L., Ryu, S.H & Suh, P (20 01) Inhibition of 18 20 21 22 23 24 25 26 27 28 the EGF-induced activation of phospholipase C-c1 by a single chain antibody fragment Oncogene 20 , 7954–7964 Johnston, ... conductance regulator, huntingtin, parkin and prion [22 ,24 ,25 ,28 ], results in aggresome formation and impairment of the UPS and, in some cases, apoptosis [24 ,28 ] For example, expression of polyglutamine-expanded ... two independent experiments MIA PaCa -2 a-bGal a-Ras a-Ras MDA-MB -23 1 1536 ± 100 (100%) 1014 ± 120 (66%) 1184 ± 81 (77%) 315 ± 32 (100%) 198 ± 18 (63%) 22 4 ± 24 (71%) to alteration of proteasome...
Ngày tải lên: 21/02/2014, 00:20
JavaFX 2.0: Introduction by Example pptx
... radius for Sphere: 2. 0 Current - volume for Sphere: 25 .1 327 4 122 8718345 Modifying DoubleProperty radius After - radius for Sphere: 50.0 After - volume for Sphere: 3 926 99.081698 724 1 How It Works ... Scene(root, 550, 25 0, Color.WHITE); // Serif with drop shadow Text text2 = new Text(50, 50, "JavaFX 2. 0: Intro by Example"); Font serif = Font.font("Serif", 30); text2.setFont(serif); text2.setFill(Color.RED); ... control pt1 cubicCurve.setControlY1( -25 ); cubicCurve.setControlX2(110); // control pt2 cubicCurve.setControlY2(175); cubicCurve.setEndX(140); // end pt (x2,y2) cubicCurve.setEndY(75); But, right...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190 pot
... 0 .23 0 .22 0.08 0.11 0. 02 0.01 0.01 0.01 620 393 60 38 40 29 62 51 13 10 27 00 1786 746 345 400 21 4 146 46 Wild-typea Y190F Y190I Y190A 1.5 2. 8 11 5.6 0.1 0 .2 0.6 1.7 2. 5 2. 7 ... 0.06 0 .28 0.01 0. 02 0.01 0.10 20 0 189 58 8.14 17 2. 23 60 106 30 15 13 1700 1360 974 29 20 0 22 6 377 11 pKa = 5.34 PNPA PABA H2 N COOH pKa = 4.67 PNPA pABglu O COOH H2N pKa = 2. 93 ... 0.34 0.58 0.18 0 .25 0.04 0.04 0.03 0. 02 260 28 8 85 28 20 14 12 100 37 8.4 3.8 20 2. 4 0.6 790 496 483 114 120 58 160 16 Wild-typea Y190F Y190I Y190A PNPA anisidine H2N Ka (mM) 10...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Modeling of ATP–ADP steady-state exchange rate mediated by the adenine nucleotide translocase in isolated mitochondria potx
... and statistical problems J ACM 8, 21 222 9 Shavit N & San PA (1967) K+-dependent uncoupling of photophosphorylation by nigericin Biochem Biophys Res Commun 28 , 27 728 3 Reed PW (1979) Ionophores Methods ... 48, 25 025 2 Letko G, Kuster U, Duszynski J & Kunz W (1980) Investigation of the dependence of the intramitochond- FEBS Journal 27 6 (20 09) 69 426 955 ê 20 09 The Authors Journal compilation ê 20 09 ... 20 09 FEBS 6953 Modeling of ANT 24 25 26 27 28 29 30 31 32 33 34 35 36 37 E Metelkin et al rial [ATP] [ADP] ratio on the respiration rate Biochim Biophys Acta 593, 19 620 3 Brawand F, Folly G & Walter...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin pptx
... followed by immunoblotting Antibodies against cyclin D1 (sc -20 044), cyclin E (sc-481), E2F1 (sc -25 1), p21Cip1 ⁄ Waf1 (sc-817, sc- 624 6), Bcl -2 (sc-509), p27Kip1 (sc-1641, sc- 528 ), c-fos (sc- 720 2) and ... J Biol Chem 27 5, 325 16– 325 22 ´ Vinals F, McKenzie FR & Pouyssegur J (20 01) Growth ˜ factor-stimulated protein synthesis is inhibited by sodium orthovanadate Eur J Biochem 26 8, 23 08 23 14 10 Huang ... 13, 12 19 23 Hengartner MP (20 00) The biochemistry of apoptosis Nature 407, 770–776 24 Eliseev RA, Dong Y-F, Sampson E, Zuscik MJ, Schwarz EM, O’Keefe RJ, Rosier RN & Drissi MH (20 08) Runx2-mediated...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: E2A participates in a fine control of pre-mature B-cell apoptosis mediated by B-cell receptor signaling via transcriptional regulation of survivin, IAP2 and caspase-8 genes pot
... MOZ)/)/MORF)/) Reference Resistance for PMA/ionomycin [22 ] [22 ] [22 ] Unpublished data [22 ] › fl fi fi fi [21 ] [21 ] [23 ] [31] [31] fi › fi fi fi [23 ] [23 ] [ 32] Unpublished data Unpublished data Unpublished ... 137, 3 42 348 FEBS Journal 27 6 (20 09) 1418–1 428 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 1 427 Fine control of pre-mature B-cell apoptosis by E2A K Toyonaga et al 11 Murre C (20 05) Helix-loop-helix ... HDACs or HATs [20 ,22 ] Our previous results revealed that GCN5 and PMA/ionomycin treatment FEBS Journal 27 6 (20 09) 1418–1 428 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 1 421 Fine control...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: A novel mechanism of TGFb-induced actin reorganization mediated by Smad proteins and Rho GTPases docx
... 531–536 14 Grunert S, Jechlinger M & Beug H (20 03) Diverse cellular and molecular mechanisms contribute to epithelial 4086 15 19 20 21 22 23 24 25 26 27 plasticity and metastasis Nat Rev Mol Cell ... A (20 00) Role of Smad proteins and transcription factor Sp1 in p21(Waf1 ⁄ Cip1) regulation by transforming growth factor-beta J Biol Chem 27 5, 29 244 29 256 Papakonstanti EA & Stournaras C (20 07) ... architecture and signaling in osmosensing Methods Enzymol 428 , 22 7 24 0 FEBS Journal 27 5 (20 08) 4074–4087 ª 20 08 The Authors Journal compilation ª 20 08 FEBS 4087 ...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene doc
... Bio ⁄ Technology 2, 63– 72 FEBS Journal 27 4 (20 07) 1110–1 122 ª 20 07 The Authors Journal compilation ª 20 07 FEBS 1 121 Regulation of the desferrioxamine gene cluster S Tunca et al ´ 23 Martı´ n JF, ... indicate the DNA fragments amplified by RT-PCR in the gene expression studies (see Fig 4) 11 12 FEBS Journal 27 4 (20 07) 1110–1 122 ª 20 07 The Authors Journal compilation ª 20 07 FEBS S Tunca et al Regulation ... cadaverine formed by lysine decarboxylation is subsequently hydroxylated to N-hydroxycadaverine by the protein encoded by desB (Fig 1) which is later FEBS Journal 27 4 (20 07) 1110–1 122 ª 20 07 The Authors...
Ngày tải lên: 16/03/2014, 11:20
Báo cáo khoa học: Deadenylation of interferon-b mRNA is mediated by both the AU-rich element in the 3¢-untranslated region and an instability sequence in the coding region pot
... translation Oncogene 11, 21 27 21 34 20 Winstall, E., Gamache, M & Raymond, V (1995) Rapid mRNA degradation mediated by the c-fos 3¢ AU-rich element and that mediated by the granulocyte-macrophage ... stability Blood 95, 1891–1899 23 Nair, A.P., Hirsch, H.H., Colombi, M & Moroni, C (1999) Cyclosporin A promotes translational silencing of autocrine 24 25 26 27 28 29 30 interleukin-3 via ribosome-associated ... infection [ 12, 21] We showed that the disappearance of IFN-b mRNA is accompanied by the shortening of its poly(A) tail As described for certain class II AREcontaining mRNAs (e.g., GM-CSF, IL-3) [22 ,23 ],...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Induction of chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI ) gene expression is mediated by ETS factor binding sites doc
... Cell Biol 12, 368±378 16 Thompson, C.B., Wang, C.Y., Ho, I.C., Bohjanen, P.R., Petryniak, B., June, C.H., Miesfeldt, S., Zhang, L., Nabel, G.J & 17 18 19 20 21 22 23 24 25 26 27 28 29 30 Karpinski, ... panels C, F, I, L, and O denote the regions seen at 100´ Scale bars are 20 lm for 100´ pictures and 20 0 lm for 20 ´ pictures 324 R Salas et al (Eur J Biochem 26 9) Ó FEBS 20 02 would also depend on ... COUP-TFI on cells of the dorsal root ganglia and some Ó FEBS 20 02 ETS factors and COUP-TFI promoter (Eur J Biochem 26 9) 321 A A 24 4 C 28 0 441 DBD Ets-1∆CE DBD Ets-1∆AE DBD 10 0 Ets-1 Ets-1∆CE Ets-1∆AE...
Ngày tải lên: 17/03/2014, 17:20
The Eugenic Marriage, Vol 2 (of 4), by W. Grant Hague This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of the Pro pptx
... important—A baby never vomits—What is the significance of socalled vomiting after feedings— Mother's milk that is unfit for baby— Fresh air for baby—Air baths for baby Page 22 3 CHAPTER XVIII BABY'S GOOD ... —FOOD FORMULAS Baby's bed—The proper way to lay baby in bed—Baby should sleep by itself—How long should a baby sleep— Why a baby cries—The habitual crier— The habit of feeding baby every time it ... of walking the floor with baby every time it cries—Jouncing, or hobbling baby—Baby needs water to drink—The evil habit of kissing baby— Establishing toilet habits—Baby's comforter—What can be...
Ngày tải lên: 22/03/2014, 23:20
Báo cáo khoa học: A large complex mediated by Moc1, Moc2 and Cpc2 regulates sexual differentiation in fission yeast ppt
... MYM2 MYM3 HT201 SPB371 YO7 YO8 YM1 SKP1 SKP2 SKP5 SKP6 SKP7 SKP8 SKP9 SKP10 SKP11 SKP 12 SKP13 SKP14 SKP20 SKP21 SKP 22 SKP24 SKP25 SKP26 SKP27 SKP29 SKP30 Genotype Source 90 h ade6 .21 0 leu1. 32 ... h90ade6 .21 0 leu1. 32 ura4-D18 rpl 32- 2-13Myc
Ngày tải lên: 23/03/2014, 05:22