After completing chapter 33, you will be able to: Describe the organs of the alimentary canal and their functions; explain the functions of the digestive system’s accessory organs; identify the nutrients absorbed by the digestive system and where they are absorbed; describe the causes, signs and symptoms, and treatments of various common diseases and disorders of the digestive system.
Trang 1The Digestive
System
Trang 2Learning Outcomes (cont.)
33.1 Describe the organs of the alimentary
canal and their functions
33.2 Explain the functions of the digestive
system’s accessory organs.
Trang 3Learning Outcomes (cont.)
33.3 Identify the nutrients absorbed by the
digestive system and where they are absorbed.
33.4 Describe the causes, signs and
symptoms, and treatments of various
common diseases and disorders of the
digestive system.
Trang 4– Alimentary canal organs form a
pathway extending from the mouth
to the anus – Accessory organs
Trang 5Characteristics of the Alimentary Canal
• Mucosa
– Epithelial tissue
– Secretes enzymes and mucus
– Absorbs nutrients
• Submucosa – loose connective tissue,
blood vessels, glands, and nerves
Trang 6Characteristics of the Alimentary Canal
Trang 7Characteristics of the Alimentary Canal
(cont.)
• Movements
– Churning ~ mixes substances
– Peristalsis ~ moves substances
Trang 8The Mouth
• Buccal cavity
• Mechanical digestion
• Starts chemical digestion
• Cheeks – hold food in mouth
• Lips – judge temperature of food
The Mouth
Trang 9The Mouth (cont.)
• Tongue
– Mixes and holds food
between teeth – Contains taste buds
– Lingual frenulum
– Lingual tonsils
• Palate
– Hard palate – Soft palate – Uvula
• Lymphatic tissue
– Palatine tonsils – Pharyngeal tonsils or adenoids
The Mouth
Trang 10The Mouth (cont.)
– Submandibular gland
– Sublingual gland
Trang 11The Mouth (cont.)
• Teeth – decrease size
Trang 12Pharynx
Trang 13Pharynx (cont.)
Swallowing
nasal and oral cavity
into oropharynx
Pharynx
Trang 15The Esophagus
• Connects pharynx to stomach
• Esophageal hiatus
• Cardiac sphincter
– Circular band of muscle
– Controls movement of food into stomach
Lower Esophagus Upper
Esophagus
Trang 16The Stomach
• Absorbs
– Alcohol – Water – Some fat-soluble drugs
– Starts protein digestion
– Moves food into small intestine
Trang 17The Stomach
• Sections
– Cardiac region
– Fundus
• Pyloric sphincter – controls movement
into the small intestine
Stomach
– Body – Pylorus
Trang 18The Stomach
• Lining – gastric glands
– Cells ~ mucous, chief, and parietal
– Stimulated by
• Parasympathetic nervous system
• Gastrin – made by the stomach
– Inhibited by cholecystokinin (CCK) made by the small
intestine
Stomach
Trang 19The Small Intestine
• Mesentery
Small Intestine
Trang 20The Small Intestine (cont.)
• Intestinal lipase
– Stimulated by
• Parasympathetic nervous system
• Stretching of the intestinal wall
Trang 21The Small Intestine (cont.)
• Absorbs most nutrients
• Wall contracts to mix and propel chyme
• Ileocecal sphincter – controls movement
of chyme into cecum of the large intestine
Trang 22The Large Intestine
Trang 23The Rectum and Anal Canal
• Defecation reflex
– Stimulated by mass movements
– Relaxation of anal sphincters
Rectum &
Anal Canal
Trang 24Apply Your Knowledge
1 Matching:
_ Water, enzymes, and mucus E Bicuspids
_ Mass of food mixed with saliva and mucus F Pharyngeal
Trang 25Apply Your Knowledge
2 What are the functions of the stomach?
ANSWER: The stomach’s functions are to receive
the bolus of food, mix it with gastric juice, start
protein digestion, and move food into the small
intestine It also absorbs alcohol, water, and some
drugs.
Trang 26Apply Your Knowledge
3 Matching:
_ Vermiform appendix A Feces
_ Crosses the abdomen B Ascending colon
_ Up right side of abdomen C Anal canal
_ S-shaped tube D Defecation reflex
_ Down left side of abdomen E Sigmoid
_ Leftover chyme F Transverse colon
_ Last section of rectum G Cecum
_ Allows anal sphincters to relax H Descending colon
Trang 27Characteristics of the Digestive Accessory Organs
• The Liver
– Hepatic lobules
• Smaller divisions of lobes
• Macrophages
– Hepatic portal vein
– Part of liver’s function
~ store vitamins and iron
To Liver
Trang 28The Liver (cont.)
• Hepatic duct
– Bile from liver
– Merges with cystic duct and forms common bile duct
• Common bile duct ~ delivers bile to
duodenum
To Liver
Trang 29The Gallbladder
• Only function is to store bile
– Cholecystokinin stimulates gallbladder to
release bile
– Bile salts
• Break up large fat globules
• Increase absorption of fatty acids, cholesterol, and fat-soluble vitamins
To Gallbladder
Trang 32• Releases bicarbonate ions into duodenum
• Stimulated to release enzymes by
– Parasympathetic nervous system
– Secretin and cholecystokinin
Trang 33Apply Your Knowledge
1 What is the route of bile through the liver and
gallbladder?
ANSWER: Bile is made in the hepatocytes and leaves the liver through the hepatic duct The hepatic duct merges with the
cystic duct from the gallbladder to form the common bile
duct, which delivers bile to the duodenum.
Trang 34Apply Your Knowledge
2 What are the pancreatic enzymes and what do
they do?
ANSWER: They are:
Pancreatic amylase – digests carbohydrates
Pancreatic lipase – digests lipids
Nucleases – digest nucleic acids
Trypsin, chymotrypsin, and carboxypeptidase – digest proteins
Good Job!
Trang 35The Absorption of Nutrients
• Nutrients – necessary food substances
Trang 36The Absorption of Nutrients (cont.)
• Carbohydrates
– Starches ~ polysaccharides
– Simple sugars
• Monosaccharides and disaccharides
– Cellulose – provides fiber or bulk
Trang 37The Absorption of Nutrients (cont.)
Trang 38The Absorption of Nutrients (cont.)
• Vitamins
– Fat-soluble
– Water-soluble
• Minerals
– Found in bones and teeth
– Used to make enzymes, cell membranes, and
proteins
• Protein
– Requirements vary – Used for growth and tissue repair
Trang 39Apply Your Knowledge
True or False:
_ Carbohydrates are starches, simple sugars, and cellulose.
_ Excess glucose is stored in the gallbladder as glycogen.
_ Triglycerides are the least abundant lipids
_ Linoleic acid is an essential fatty acid.
_ A, D, E and K are water-soluble vitamins.
_ Minerals are used by cells to make enzymes.
fat-soluble
Trang 40Aging and the Digestive System
• Dietary changes due to
– Isolation– Depression
Trang 41Common Diseases and Disorders
Disease/Disorder Description
Appendicitis Inflammation of the appendix;
can be life-threatening if not treated promptly
Cirrhosis Chronic liver disease; normal
tissue is replaced with nonfunctional scar tissueCholelithiasis (gall
stones) Hard deposits of cholesterol or bilirubin in the gall bladder
Trang 42Common Diseases and Disorders
Disease/Disorder Description
intestine; can be acute or chronic
Colorectal cancer Arises from lining of rectum or
colon; curable if treated earlyConstipation Difficult defecation
Crohn’s disease Inflammatory bowel disease;
typically effects small intestine
Trang 43Common Diseases and Disorders (cont.)
Disease/Disorder Description
usually self-limitingDiverticulitis Inflammation of diverticula
Diverticulosis – diverticula with
no inflammation
lining; “upset stomach”
Trang 44Common Diseases and Disorders (cont.)
Disease/Disorder Description
disease (GERD); stomach acids push into esophagusHemorrhoids Varicose veins of rectum or anusHepatitis Inflammation of the liver; various
typesHiatal hernia Portion of stomach protrudes
into the chest through an opening in the diaphragm
Trang 45Common Diseases and Disorders (cont.)
Disease/Disorder Description
Inguinal hernia Portion of large intestine
protrudes in the inguinal canal (where thigh and trunk meet) or,
in males, into the scrotum
Oral cancer Usually involves the lips or
tongue but can occur anywhere
in the mouth; tends to spread rapidly
Trang 46Common Diseases and Disorders (cont.)
Disease/Disorder Description
Pancreatic cancer Fourth leading cause of cancer
deaths in the U.S
Stomach cancer Commonly in cardiac portion of
the stomach; occurs more frequently in Japan, Chili, and Iceland
Stomach ulcers Breakdown in lining of the
stomach
Trang 47Apply Your Knowledge
Matching:
_ Inflammation of the large intestine A Heartburn
_ Inflammatory bowel disease B Hemorrhoids
_ Watery and frequent feces C Constipation
_ Difficult defecation D Crohn’s disease
_ Inflammation of the stomach lining E Colitis
_ Inflammation of pouches in the intestinal wall F Diarrhea
Trang 48In Summary
33.1 The pathway of food through the
alimentary canal starts with the mouth and continues through the pharynx,
esophagus, stomach, small intestine,
large intestine, and anal canal
Trang 49In Summary (cont.)
33.2 The accessory organs to the digestive
system include the liver, gallbladder, and pancreas
33.3 Nutrients absorbed by the body include
carbohydrates, proteins, lipids, vitamins, minerals, and water Most of the
absorption takes place in the small
intestine
Trang 50In Summary (cont.)
33.4 There are many common diseases and
disorders of the digestive system with varied signs, symptoms, and
treatments
Trang 51Take all that is given whether wealth, love
or language; nothing comes by mistake and with good digestion all
can be turned to
health
~ George Herbert
End of Chapter 33