sacofactor coenzyme

Cofactors Groups or molecules other than amino acid residues which are important to catalysis... Catalysis by Coenzymes Some common coenzymes Transfers ¢ Acyl groups and others... Vita

Cofactors and

Coenzymes

Cofactors

Groups or molecules (other than amino acid

residues) which are important to catalysis

Catalysis by Coenzymes

Some common coenzymes Transfers

¢ Acyl groups and others

Vitamin Derived Coenzymes

Derived Deficiency

Coenzyme from causes

FAD Riboflavin Dermatitis

Vitamin Derived Coenzymes

Coenzyme A Pantothenate Fatigue

Examples of Coenzyme Catalysis

Uncatalyzed reaction

Examples of Coenzyme Catalysis

Catalysis with pyridoxal phosphate (Vitamin Bạ

Examples of Coenzyme Catalysis

Nicotinamide adenine dinucleotide and alcohol dehydrogenase

Examples of Coenzyme Catalysis

Reactive site

†

NADH and NADPH Electrons Nicotinate (niacin)

FMNH, Electrons Riboflavin (vitamin B2) Coenzyme A Acyl Pantothenate

S-Adenosylmethionine Methyl

Note: Many of the activated carriers are coenzymes that are derived from water-soluble

vitamins (Section 8.6.1)

TABLE 14.3 Types of chemical reactions in metabolism

Cleavage of bonds by the addition of water

Addition of functional groups to double

bonds or their removal to form double

bonds

Coenzyme A ở