... anti-inflammatory drugs such as aspirin could reduce the risk of CRC [9, 10] and adenomatous polyps [11] Genetic factors contribute to the development of CRC through an inflammatory process To date, ... genotype of the tagSNP rs2282151, the expression levels of HSP90AB1, and the risk of CRC As shown in Fig 3, the C allele of rs2282151 was associated with increased risk of CRC Meanwhile, the C allele ... regulator NFκB is inactivated in the cytoplasm by binding to its inhibitor IκB Phosphorylation and degradation of IκB proteins lead to the release and nuclear localization of NFκB proteins, which then
Ngày tải lên: 20/09/2020, 18:20
... proportion of women The activities of the Vietnamese collaborators have, therefore, more than compensated for the negative effects of the budgetary problems stemming from the exchange rate problems The ... particular circumstances They must also be aware of the impact of their actions on the environment, so as to minimise pollution, and maintain the safety of their co-workers and themselves This means ... activities of our Vietnamese collaborators are very significant and indicate their appreciation of the potential of the technology that they have been provided with by the project As the project
Ngày tải lên: 22/06/2014, 13:20
Báo cáo y học: "Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow" doc
... cytokines The transmembrane domain of both IL-1 receptors (IL-1 receptor I and IL-1 receptor II) is susceptible to lysis by proteases, leading to the release of a soluble form of the receptor ... place during the development of OA is the presence of synovial inflammation The synthesis and release of a number of Trang 8mediators by the inflamed tissue is an important factor in thedevelopment ... proliferator-activated recep-tor; RA = rheumatoid arthritis; RANK = receptor activator of nuclear factor-κB; sIL-1R = soluble form of IL-1 receptor Abstract Osteoarthritis (OA), the most common of
Ngày tải lên: 09/08/2014, 07:20
6 ways to measure the ROI of social media
... promotion • COST PER VISITOR • Divide the total cost by the number of visitors to determine the cost per visitor Divide cost per visitor from display by cost per visitor from social Outcomes ... per visitor? • No But you simply need the whole budget for the buy (including creative development) and the number of visitors (not the number of impressions) to calculate the cost per visitor ... traffic during the campaign to measure the increase • COST • Determine the cost of each promotion Be sure to count all expenses, from design fees to media buys, to capture the true cost of each promotion
Ngày tải lên: 20/02/2017, 10:54
Relying on ongoing monitoring to test controls performance to reduce the scope of separate testing
... further the costs of documentation as well as testing costs; and 4 Rely on ongoing monitoring to test the performance of controls and to reduce the scope of separate testing These are the issues ... business and then develop a top-down approach to financial controls reporting Issue #4: Relying on Ongoing Monitoring to Test Controls Performance, to Reduce the Scope of Separate Testing Too often, ... ongoing monitoring performed by the owner of the process or activity Then, independent testing separate evaluations can be done of this ongoing monitoring, and not of the performance of the controls
Ngày tải lên: 06/04/2018, 11:16
Breastfeeding and vitamin D supplementation reduce the risk of Kawasaki disease in a German populationbased case-control study
... were performed to obtain odds ratios (OR) for various risk factors among the case-control pairs Simple measures of association were used to assess the impact of these factors on the clinical course ... were asked whether they might be able to recruit one of their child’s friends to take part in the survey If no immediate friend of the KD cases was available or interested, then the treating paediatrician ... 0.141) Influence of risk factors on the clinical course We tested whether the duration of breastfeeding and of vitamin D supplementation influenced the clinical course of KD cases The clinical variables
Ngày tải lên: 01/02/2020, 03:59
Development and external validation of nomograms to predict the risk of skeletal metastasis at the time of diagnosis and skeletal metastasis-free survival in nasopharyngeal carcinoma
... is used in the clinic to predict the presence of bone metastases in a range of cancers, including lung cancer and prostate cancer [12, 13] The hydrolase ALP dephosphorylates a variety of molecules ... in NPC Points refers to the value of each factor included in the nomogram; total points, total points for all factors; 1/3/5-year survival, survival probability based on total points; ALP, alkaline ... discriminative ability compared to the TMM classification of the Table 1 Associations between the clinical and laboratory characteristics of the patients and SMAD as indicated by the chi-square test or
Ngày tải lên: 06/08/2020, 04:02
Temporal trends in the risk of developing multiple primary cancers: A systematic review
... trends In order to better understand temporal trends in the risk of developing MPCs, we performed a systematic re-view of the scientific literature to determine whether the risk of MPCs has increased ... 2.8 million survivors of adult cancer over the period of 1943 to 2012 [31–56], with 178,091 MPCs identified Four of them reported the risk of developing MPCs following first cancer with all sites ... more. Second cancer defined as the site and the histology are distinct from the first Second cancers at the same site as the first or at a different site but with the same histology as the first
Ngày tải lên: 20/09/2020, 18:30
how to reduce the number of rating scale items without predictability loss
... V20 have one of the top factor loadings in the full rating scale, but they do not still have the most predictive power Therefore, it is impossible to indicate the ordinal number of the rating scale ... items The results revealed that the reliability of the reduced model CR = 822 and is lower than the reliability of the full model of 0.1 (CR =.929) Therefore, it can be concluded that the reliability ... used to verify the structure of our results CFA is a factor analysis which purpose is to verify the structural validity whether items belong to scales and what are their factor loading Factor
Ngày tải lên: 04/12/2022, 10:36
maternal and perinatal conditions and the risk of developing celiac disease during childhood
... dysbiosis, all of which are suspected to play a role of increasing the risk of auto-immune disorders [39] Moreover, we found a rather large reduction in CD risk to be associated with PROM Due to the ruptured ... of the study variables and the research findings All authors contributed to the selection of the studied variables, choice of study design, interpretation of study findings, and revision of the ... system is also dependenton a healthy gut microbiota Colonization of the gut begins at delivery with the transferral of microflora from the ma-ternal birth canal, faeces and skin The neonates’ microbiota
Ngày tải lên: 04/12/2022, 15:13
Research Paper: The Relationship of Basic and Instrumental Activities of Daily Living With the Risk of Developing Pressure Ulcer
... moderate risk (total score 13-14), mild risk (total score 15-18), and no risk (total score 19-23) To determine the reliability of the screening tools, after explaining the process to the caregivers ... addition, the extent of dependency to other family members may prepare the ground for develop-ment of PU The current study aims at investigating the relation-ship of BADL and IADL with the risk of developing ... perform their ADLs well are at higher risk of developing PU (Mostoufian 2015) Since the development of a PU is multifactorial and poorly un-derstood, systematic monitoring of its incidence, risk
Ngày tải lên: 28/03/2023, 16:08
báo cáo khoa học: " Individual and setting level predictors of the implementation of a skin cancer prevention program: a multilevel analysis" docx
... Although the role of these factors is well described in the literature [10,13], little research has been done on identifying their relative contributions to the implemen-tation of effective skin cancer ... predictor of implementation in the final model was the number of weekly pool visitors In this study, an inverse relationship was observed between the number of weekly pool visitors and the level of ... visi-tors This explanation suggests that, to increase imple-mentation of the intervention, the amount of intervention materials provided for the pools should be proportional to the number of visitors
Ngày tải lên: 10/08/2014, 10:22
The Shark and the Goldfish Positive Ways to Thrive During Waves of Change by Jon Gordon_8 potx
... at the rest of the list, they found it difficult toconnect a third pertinent entity to the tree Some seemed to be obviouslyconnected to each other, but none seemed to be closely connected to thecluster ... each of the three entities on the cluster with each of the remaining entities on the list “If to keeptheir costs low, stores hire personnel with minimal skills, then customersquestion the value of ... was also something they didn’t want to address directly Whowere they to try to change their customers’ customers’ hiring practices?They decided then to take a look at the entity the core problem
Ngày tải lên: 21/06/2014, 12:20
The Shark and the Goldfish Positive Ways to Thrive During Waves of Change by Jon Gordon_9 pot
... believe that you need to haveyour towel on the bar next to the tub, and in order for Jenn to be on timefor school, she wants to have her towel on the bar next to the tub (I point to the B and C entities, ... 9.3 shows the five-entity structure of the cloud I began withthe boxes labeled D and D′ These are the parts of the cloud that describethe elements of the situation that are perceived to be in ... Goldratt and all of the tools having names descriptive oftheir processes? It was obvious to me that the common objective was tosuccessfully spread the principles and practices of TOC I wrote my
Ngày tải lên: 21/06/2014, 12:20
The Shark and the Goldfish Positive Ways to Thrive During Waves of Change by Jon Gordon_10 pdf
... for one of the objectives, preferably the one that appears to be the most difficult to achieve, or the one that you know intuitively will take the longest to accomplish. Most of the other objectives, ... the subject of your current reality tree, the purpose of the system, or a key aspect of what forms the system’s identity The transition from “What to Change to To What to ... Remember that the future reality tree process calls for you to list the positives and negatives of the injection The positives of the injection (the objectives of the future
Ngày tải lên: 21/06/2014, 12:20
The Shark and the Goldfish Positive Ways to Thrive During Waves of Change by Jon Gordon_11 ppt
... litter the pages of the book with multitudes of trees because I wanted to focus on process rather than the content of what others had done in the past I tried to put myself in the position of someone ... set of guidelines to the thinking processes Some may wonder why there are not many more examples of trees in the book It is certainly not due to lack of material I made the decision not to litter ... understand the nature of the problem What if the party to whom you need to communicate the content of the current reality tree is someone who is, or thinks he is, directly responsible for the environment
Ngày tải lên: 21/06/2014, 12:20
GT-repeat polymorphism in the heme oxygenase1 gene promoter and the risk of carotid atherosclerosis related to arsenic exposure ppt
... ORs with the 95% CIs for the clas-sic risk factors for the patient and control groups of the two cohorts Aging and being male gender were the two Trang 5common risk factors that had the strongest ... significant, the frequency of total cholesterol of≥ 200 mg/dL or trigly-cerides of ≥ 150 mg/dL was found to be higher in the patient group compared to the control group (0.05 ≤ p < 0.10) Other factors, ... history of diabetes, revealed no evidence of being associated with carotid atherosclerosis in the Lanyang cohort On the other hand, having a history of diabetes was a significant risk factor,
Ngày tải lên: 10/08/2014, 05:21
Eat for Life The Food and Nutrition Board''s Guide to Reducing Your Risk of Chronic Disease
... guidelines The guidelines were formulated to reduce therisk of not just one illness but an entire spectrum of chronic diseases They Trang 20also take into account whether making a dietary change to reduce ... increasethe risk of developing certain forms of cancer, especially cancers of theesophagus, colon (large bowel), prostate, and breast Certain dietary patterns canincrease the likelihood of dental ... food we eat and how it affectsour bodies Trang 13Nevertheless, the strength of the evidence, the severity of the risk, and theability of people to make informed choices can be used as a foundation
Ngày tải lên: 09/08/2015, 12:31
Quick and easy ways to make the absolute most out of every customer contact
... AND EASY WAYS TO MAKE THE 'ABSOLUE Trang 2In telephone selling reqC —— decision maker is getting tougher and tougner Trang 4 So)ilimakes'qood Senseto maximize fevenvimomentotiaicall ... Trang 21 Develop alistof'3-5 questions z (no more) to gauge your : customer's level of satisfaction In certain key areas pao Trang 23Ialclentrealyslovessyourcompany;askafitheyill Me OUTMNCNANEN ... 13 IF you have quantity discounts, offer them to Your clenL If you have an [ioo/(09-3)0.-0L00 0! Trang 14ee Trang 186, IS Your client Sonnctining personalltonelploolstemyour Trang 20<*>
Ngày tải lên: 10/03/2016, 11:30
Cancer Research UK’s strategy 2009–2014: Cancer Research UK’s aim is to reduce the number of deaths from cancer. Our future plans are ambitious, but they are in line with the challenge and the responsibility we face. docx
... goals that, together with our partners, we aim to accomplish by the year 2020: ã People will know how to reduce their risk of cancer Three-quarters of the UK public will be aware of the main lifestyle ... likely to get cancer The chances of a person developing cancer up to the age of 75 will fall from more than one in four to one in five ã Cancer will be diagnosed earlier Two-thirds of all cancer ... thousands of new cases of the disease, both in the UK and across the world. Cancer Research UK has been at the heart of this progress thanks to the sustained support and generosity of the UK public. The...
Ngày tải lên: 22/03/2014, 16:21