the value of muscle exercise in patients with als

... strongly increasing PCT of 17.88 ng/mL after 72 hours. The patient had an intra-abdominal infection. Nosocomial infection was found in 53% (19/36) of these patients, and the sources of infection ... 4 of 10 decreased in 130 patients and increased in the remain- ing 25 pati ents, but t he change in PCT concentration was not associated with mortality (P =0.25).Of the patients with decreasing ... intra-abdominal infections in the nosocomial group; of these patients, 52.9% had ongoing antimicrobial treatment. In general, PCT concentrations may also be influenced by the organ- ism causing

Ngày tải lên: 14/08/2014, 07:21

... patient prognosis in TNBC Accordingly, we investigated the expression profiles of HER family genes in patients with TNBC to determine the prognostic value and clinical implications of HER family ... II) The baseline characteristics were similar in training and validation cohorts However, the patients in the val-idation cohort had a higher stage of breast cancer than those in the training ... 8and the validation set (Fig 6) The results of ROC analysisrevealed that the value of ERBB4 expression strengthened the predictive efficacy of TNM stage at diagnosis in both the training and the

Ngày tải lên: 21/09/2020, 02:03

... bevacizumab in cancer patients in a 5-year period after the beginning of chemotherapy treatment and comparison with the control group Methods: The study population consists of adult patients with metastatic ... The aim of the present study was to estimate the effect of systemic administration of bevacizumab in survival and the incidence of cardiovascular events in surveillance of five years from the ... All these results, may insinuate patients with thromboembolic events in the past, including myocardial infarction, into a ‘high-risk’ group for systemic treatment of bevazicumab If these patients

Ngày tải lên: 19/11/2022, 11:40

... cytokine a prime candidate also in the pathogenesis of SS Increased serum levels and salivary gland expression of IL-18 in patients with SS is in keeping with an active role for this cytokine in the ... counted The histological evaluation of the number of foci, the presence of IL-18 in inflammatory foci and ducts, the degree of organization of the mononuclear aggregates, and the presence of germinal ... blocked with Doublestain Block for 3 min at RT The sections were rinsed in TBS and stained for anti-IL-18 as described above To verify the specificity of the staining, sections with omission of the

Ngày tải lên: 09/08/2014, 01:23

... IRFs, with the mth IRF describing the probability of scor-ing in category m or higher as a function ofθ The prob-ability of answering within a particular category can easily be derived from the ... bjm) The slope parameter a, indicates the discrimination power of an item; the higher the slope parameter a, the steeper the IRF and the better the item discriminates low θ values from high θ values ... lower-bound value c Therefore, this lower-bound c controls the minimum scalability level of the items to be included in the scale and must be chosen by the user The following rules of thumb for choosing

Ngày tải lên: 11/08/2014, 15:22

... if they deemed it necessary for their patients After enrollment, however, specific clinical interventions were not mandated other than the initiation of RLAT at the beginning of the study; therefore, ... involved in the interpretation of data and in the critical drafting and revising of the manuscript for important intellectual content. All authors read and approved the final manuscript. Competing interests ... RLAT in the injection log within 28 days prior to the visit Because RLAT steady-state plasma concentrations are main-tained at a minimum of 4 weeks after the last injection [14], the 28-day interval

Ngày tải lên: 11/08/2014, 16:20

... transit in these patients. Therefore, the objective of this study is to investigate the symptomatology of bloating, the role of gastrointestinal transit and effect of tegaserod in non-diarrhea IBS patients ... patients with bloating. In the first part of this thesis, the symptoms profiles of non-diarrhea IBS patients with bloating were assessed. It was showed that there were more common complaints with ... A STUDY OF BLOATING SYMPTOMATOLOGY, THE ROLE OF GASTROINTESTINAL TRANSIT AND THE RESPONSE TO TREATMENT WITH THE 5-HT4 RECEPTOR AGONIST IN PATIENTS WITH BLOATING PREDOMINANT IRRITABLE

Ngày tải lên: 26/09/2015, 10:05

... collaterals visible to the ischemic site (+) Grade 1: Slow collaterals to the periphery of the ischemic site with persistence of some of the defect (+) Grade 2: Rapid collaterals to the periphery of ... Hypo attennuating brain tisue including: Cortical sulcal effacement, loss of the insular ribbon, obscuration of the lentiform nucleus, loss of gray-white matter differentiation in the basal ganglia ... clot burden were determined on baseline CTA The collateral score grades distal arteries filling with a 4-point scale with (+) 0 constituting absent collaterals (0% filling of the occluded Trang 10territory),

Ngày tải lên: 08/01/2020, 16:41

... trial is the first step in the translation of therapeutic potential of mycophenolate mofetil emerging from in vitro and animal studies into the clinical domain It is designed to assess the efficacy ... considered to be the first step in the translation of therapeutic potential of myco-phenolate mofetil emerging from in vitro and animal studies into the clinical domain before the drug develop-ment ... to assess the safety and tolerability of the drug The present study also aims to explore the pharmacokinetics of mycophenolate mofetil, biomarkers, and the quality of life in patients with high-grade

Ngày tải lên: 17/06/2020, 11:32

... level of comorbidity was also associated with less use of chemo-therapy, with a rate of 82% in patients with no comor-bidities falling to just 58.7% in those with a CCI of 2 or more Nevertheless, ... 7The most frequent chemotherapy schemes wereCAPOX (capecitabine, oxaliplatin) in 49.4% of patients, FOLFOX (5- Fluorouracil, oxaliplatin) in 26.9% and capecitabine in monotherapy in 20% of the ... toxicity of chemotherapy and radiotherapy in older patients with colorectal cancer might explain a lower adherence to clinical practice guidelines Further, the ex-clusion of older patients from clinical

Ngày tải lên: 17/06/2020, 16:46

... were applied Patients with multiple synchronous primaries (i.e., 3 or more different tumor types, including the index tumor) within 30 days of the index date were excluded The following rules were ... determine the primary tumor type for patients with a second tumor type recorded within 30 days of the index tumor Lung, liver, brain and bone tumors were considered to be metastases of the index ... were the most common index tumor types (Table 1) The number of patients identified in each year of the study increased from 16,525 in 2004 to 52,534 in 2013, with slightly more than half of study

Ngày tải lên: 23/07/2020, 23:55

... of the Declaration of Helsinki in 1995 All patients were in-formed of the investigational nature of this study and provided written informed consent This retrospective study was approved by the ... patients with ulcerative colitis, nine patients who had received preoperative therapy and 26 patients with multiple malignancies within five years Therefore, 218 patients remained and were analyzed in ... categorized the patients into four groups according to the combination of their preoperative and postopera-tive PNI in the same manner as the exploratory study The patients in group A exhibited a

Ngày tải lên: 28/09/2020, 10:09

... of retinal lesions in patients with systemic Lupus erythematosus” with the two following goals: 1.  Describing   the   clinical   and   subclinical   characteristics   of   retinal   lesions in Lupus patients 2.  Assessing the results of treatment of retinal lesions in patients with ... even leading to death.The ophthalmic manifestations in Lupus can threaten the vision and impair the patient’s life quality, which is also an indicator of advanced systemic disease. In Vietnam, there are currently no reports of eye injuries caused by the pathological process of Lupus, especially the fundus lesions. So we proceed to the topic: “Studying the clinical, subclinical characteristics and treatment  of retinal lesions in patients with systemic Lupus erythematosus” with the two following goals: ... or there is a risk of vitreous body hemorrhage requiring intraocular injection Avastin + In case of examination, there is a complication of proliferation causing retinal detachment requiring surgery

Ngày tải lên: 29/09/2020, 15:02

... differences in the detection rate of LVI could be due to variations in the detection methods The use of H & E staining, an elastic fiber stain and immunostaining are currently ac-cepted methods in the ... the view that the presence of LVI in GC is a promising indicator of tumor aggressiveness; providing additional information regarding the risk of cancer recurrence and mortality The addition of ... 8staining complemented by immunostaining with CD34[22] However, a study by Kim et al had indicated that LVI was detected in 44.3% of GC patients by immuno-staining with D2-40 and CD31 [16] The

Ngày tải lên: 30/09/2020, 10:45

... targeted training-therapeutic measures involving isometric muscle exercise in these patients There are, however, nu-merous findings that indicate the positive effect of targeted physical training measures ... controlled, explorative intervention study with the intention to determine the feasi-bility of a resistance training program for strengthening the paravertebral muscles in patients with spinal bone metasta-ses ... after the end of RT (t2) In addition, the evaluation of the mobility aspect included the performance of the chair-stand test at the individual investi-gation intervals The item taken as the secondary

Ngày tải lên: 05/11/2020, 01:05

... contributed to the further writing of the manuscript and approved the final version of the manuscript. Competing interests All authors of the manuscript were involved in the development of eSano BackCare-BP ... remain blinded Therefore, both participants and interviewers will be reminded of the reason and im-portance of blinding at the beginning of each interview Moreover, performance bias will be minimized, ... Additionally patients will be excluded in case of d) participation in on-going psychotherapy, completed psychotherapy in the past 6 months, or being on a waiting list for psychotherapy (be-ginning within

Ngày tải lên: 04/12/2022, 14:59

... resulting signs and symptoms may include:- Sudden and rapidly intensifying pain in the upper right portion of your abdomen- Sudden and rapidly intensifying pain in the center of your abdomen, just below ... about the safety of the procedure, the surgeon's qualifications, wound healing, and potential complications Patients often worry about pain during and after surgery, the effects of anesthesia, ... impacts patients both physically and psychologically, influencing their thoughts, feelings, and behaviors Physically, it triggers the release of epinephrine, leading to vasoconstriction, increased

Ngày tải lên: 03/04/2025, 22:41

... again resulting in evidence of association but also with many non specific or conflicting findings The find-ing of an HPA dysfunction in depressed patients durfind-ing acute phase has led to the ... already high in the first rating and increased during the course of the training [64] The training sessions were orga-nized in a standardized manner After an introduction section on the theoretic ... role in the conception of the study design, in the writing of the manuscript or the decision to submit the manuscript for publication The BMBF has no role in the currently ongoing collection of

Ngày tải lên: 11/08/2014, 16:23

... clini- cal trial, the knowledge of instrument’ s responsiveness helps in the selection of measures, in sett ing the correct sample size and assists in prioritising the number of outcomes to be ... used in conjunction with the QLQ-C30. The FACT-C combines the FACT-G with a CRC subscale (CCS). The 3 questionnaires FACT-C, QLQ-C30 and QLQ-CR38 were administrated together. The order in which these ... courses of chemotherapy at two weeks interval in patients who reported no change in their state of health. To assess reliability, a sample of 30 patients with stable health between the 2 testing

Ngày tải lên: 20/06/2014, 15:20

... subtraction of the next eigenvalue in order to integrate the irregular eigenvalue variation A smoother form of the second discriminant function can be thus obtained The shapes of the two discriminant ... MATRIX EIGENVALUES The theoretical validity of this criterion will be demonstrated in the following, on the simplified case of the linear variation of the autocorrelation matrix eigenvalues, as ... for these signals there is a slope variation between the two classes of eigenvalues The main idea for defining the second discriminant function is then to exploit this slope variation to distinguish

Ngày tải lên: 23/06/2014, 01:20