... within the preceding 12 months Respondents selected from a list of settings all those settings in which they learned a specific competency or skill They then indicated the single “best” learning ... a range of potential developmental activities RESEARCH QUESTION DAL staff members raised questions pertaining to the nature and extent of airmen development occurring within the Training, Exercise, ... as a setting for skill broadening and competency development In doing so, this research addresses the larger issue of whether the learning that occurs during deployments merits tracking This
Ngày tải lên: 23/03/2014, 01:20
... The Role of Government in Economic DevelopmentThere have been three phases in the dominant view concerning the optimal role ofgovernment in development The Government as Prime Mover Phase: In ... spread of the Industrial Revolution duringthe nineteenth century; and the development of developing countries during the Goldenera of economic development between the end of World War II and the ... favoring the influx of unskilled labor Where the country was too poorto finance the banks required to finance industry, the state promoted the establishment offinancial intermediaries, invested in
Ngày tải lên: 31/03/2014, 05:21
Evaluation of the role of autophagy in fungal development and pathogenesis 2
... Atg24 bind PtdIns(3)P and belong to the sorting nexin family that functions in protein trafficking from the Golgi to the endosome (Hettema et al., 2003); and are involved in the Cvt pathway in S. ... XcaI) in one step, so that the newly created plasmid contained an in- frame insertion of RFP ORF at the translational start site within the ATG8 coding sequence while retaining the ... conidiation in atg8∆. More interestingly, ectopic expression of Sga1, the vacuolar glucoamylase that acts following autophagy-based delivery of glycogen into the vacuole, in the cytosol, could bypass the
Ngày tải lên: 11/09/2015, 10:01
Evaluation of the role of autophagy in fungal development and pathogenesis 3
... OP-2 strains. The indicated strains were initially grown in the dark for days and then subjected to constant illumination to induce conidiation. At the specified time-points post induction, the fungal ... regulation of conidiation, and to elucidate the exact physiological role of autophagy in the process of asexual development in Magnaporthe. A key finding was the remarkable suppression of atg8Δ ... breakdown in the cytoplasm instead of the vacuole, thus bypassing the requirement of autophagic machinery for glycogen transport to the vacuoles. To verify if the increased conidiation in the atg8∆
Ngày tải lên: 11/09/2015, 10:01
Evaluation of the role of autophagy in fungal development and pathogenesis
... processing and Atg8p targeting to autophagosomes in Magnaporthe 53 3.2.5 Induction and subcellular localization of RFP-Atg8 in Magnaporthe 56 3.2.6 Suppression of conidiation defects in atg8∆ ... characterization of an atg20∆ mutant in Magnaporthe 90 4.2.2 Subcellular localization of Atg20 90 4.2.3 Investigation of non-selective autophagy and the Cvt pathway in the atg20∆ mutant 98 4.2.4 Investigation ... required for Magnaporthe conidiogenesis and pathogenesis 105 4.2.5 Investigation of retrieval trafficking pathway in the atg20∆ mutant 112 4.2.6 Investigation of vacuolar morphology in atg20∆ 116
Ngày tải lên: 11/09/2015, 10:01
The Role of Traceability in Sustainable Supply Chain Management
... points out that there is no uniform understanding of tracking and tracing The definitions vary from the dimensions of the type of activities that are included and the organizational context in ... identify the origin of an item or group of items, through records, upstream in the supply chain" Figure 1 shows information flows of tracking and tracing in the supply chain Although the quality ... details of these identification technologies are in section 3.3 Scope of the tracking and tracing system The scope of the tracking and tracing system is defined by the three dimensions of transformation:
Ngày tải lên: 10/12/2016, 09:55
The role of communication in organisational change
... an indicator of the amount of uncertainty and on the (lack of) quality of the information given about the organisational change So besides of direct effects of the informative function of communication, ... tasks on the same way I used to do them” In this sense feelings of uncertainty are about the process of the change, the personal and social consequences of the change P4 High levels of uncertainty ... made in this paper are that information of the change, feelings of a community within the organisation which is undergoing the change, and uncertainty have an influence on readiness for change The
Ngày tải lên: 13/07/2020, 20:36
The role of communication in breast cancer screening: A qualitative study with Australian experts
... assisting decision making in clinical practice and there is ongoing interest in promot-ing ethical care alongside or as part of evidence based medicine [66] There is increasing recognition that the ... time there has been growing interest in encouraging and supporting members of the public to be more informed about health matters, including screening, and more engaged in decisions about their ... screening communications Further data, including quota-tions from experts that encapsulates the range of reasoning about communications, is included in Additional file 2 The major concerns of experts
Ngày tải lên: 22/09/2020, 23:55
The role of entrepreneurs in economic development
... Trang 1VIỆN NC QUẢN LÝ KINH TẾ TW TRUNG TÂM THÔNG TIN – TƯ LIỆU THÔNG TIN CHUYÊN ĐỀ VAI TRÒ CỦA DOANH NHÂN TRONG PHÁT TRIỂN KINH TẾ THE ROLE OF ENTREPRENEURS IN ECONOMIC DEVELOPMENT 9 Trang ... 2VIỆN NC QUẢN LÝ KINH TẾ TW TRUNG TÂM THÔNG TIN – TƯ LIỆU VAI TRÒ CỦA DOANH NHÂN TRONG PHÁT TRIỂN KINH TẾ THE ROLE OF ENTREPRENEURS IN ECONOMIC DEVELOPMENT TRUNG TÂM THÔNG TIN – TƯ LIỆU Tel ... tiếp thu những kiến thức kinh tế mới nhất, những kinh nghiệm quản trị kinh doanh tốt nhất từ các giáo sư, chuyên gia kinh tế, các nhà kinh doanh thành đạt Cung cấp thông tin cho doanh nhân, DN cũng
Ngày tải lên: 23/01/2021, 11:32
The UN Model Double Taxation Convention in the context of Financing for Sustainable Development
... The UN Model Double Taxation Convention in the context of Financing for Sustainable Development Alexander Trepelkov Director, Financing for Development Office Department of Economic ... prevent having income from cross-border investment taxed twice (i.e both in the host country of the Why countries need Double Tax Treaties? investment and in the residence country of the investor), ... Take into account recent developments in the area of international tax policies of both developing and developed countries • Seek further consistency with the OECD Model, where in line with the
Ngày tải lên: 05/09/2013, 14:19
The role of pictures in improving health communication: A review of research on attention, comprehension, recall, and adherence doc
... mean- ingless. Readers may then use the picture to guess the intended meaning, often incorrectly, and think that they understand the message, thereby interfering with their comprehension. They ... a video tape of animated cartoons explaining the need for a polio vaccine. The information contained in the videotape was the same as in the leaflet. Both versions were available in English and ... discussed: (1) drawing attention to the materials or message, (2) helping people comprehend the information being presented, (3) increasing recall of the message, and (4) increasing the likelihood
Ngày tải lên: 14/03/2014, 21:20
Development of sphingosine kinase (SPHK) inhibitors and the role of sphingolipids in adult stem cell proliferation and differentiation 2
... change Within the linear range of the assay (~5-25μg/mL), the more protein present, the more the Coomassie Blue binds changing the absorbance of the sample After getting cell lysates from the CHO ... requirement of Graduate Program in BioEngineering, investigations of the synthetic compounds were more on their applications in tissue engineering, which is in stem cells differentiation, in this ... D-erythro-sphingosine (Figure 2.1a) is a natural substrate for SPHKs The design of the compounds was based on investigations of: 1) changing the fatty acid carbon chain length; 2) converting the existing
Ngày tải lên: 11/09/2015, 16:06
Development of sphingosine kinase (SPHK) inhibitors and the role of sphingolipids in adult stem cell proliferation and differentiation 3
... Staining 3.1.3.1 Alizarin Red S Staining Alizarin Red S staining is widely used to evaluate the calcium-rich deposits generated by cells In this study, the staining was used to detect the mineralization ... days of culture, the cells grown in the presence of either 1μM of DMS, 0.5μM of CP6, 1μM of CP6, or 5μM of CP6, showed more lipid droplets staining than that from the cells cultured without the inhibitors ... staining in each sample was quantified by dissolving the staining with 100% of isopropanol and detecting the absorbance at 500nm 3.1.3.3 Fluorescence Immunostaining Fluorescence immunostaining
Ngày tải lên: 11/09/2015, 16:06
Development of sphingosine kinase (SPHK) inhibitors and the role of sphingolipids in adult stem cell proliferation and differentiation 4
... Cells cultured in S1P-supplemented media were then measured for their stemness maintenance by checking their morphology change, the cell surface markers expression profile, and their osteogenic ... were aliquoted into tubes, and the methanol was evaporated by a stream of nitrogen A suitable amount of 0.1% fat-acid free bovine serum albumin (FAF-BSA) was then added into the tubes to make ... washed twice with 1x PBS and starved in serum-free DMEM for half an hour 1μM S1P was then added into the wells and incubated at 37°C for 5min, 10min, 30min, and 60min to look for ERK activation Human
Ngày tải lên: 11/09/2015, 16:06
Development of sphingosine kinase (SPHK) inhibitors and the role of sphingolipids in adult stem cell proliferation and differentiation 6
... "Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase." ... et al (1998) “N,N-Dimethylsphingosine Is a Potent Competitive Inhibitor of Sphingosine Kinase but Not of Protein Kinase C: Modulation of Cellular Levels of Sphingosine 1-Phosphate and Ceramide.” ... “Characterization of N, N-dimethyl-d-erythro-sphingosine-induced apoptosis and signaling in U937 cells: independence of sphingosine kinase inhibition.” Prostaglandins & Other Lipid Mediators 86(1-4):18-25
Ngày tải lên: 11/09/2015, 16:06
Development of sphingosine kinase (SPHK) inhibitors and the role of sphingolipids in adult stem cell proliferation and differentiation
... Geoffroy et al., 2004) Figure 1.1 Structure of Sphingosine, D-erythro Sphingomyelin, the major membrane sphingolipid, is the precursor of the bioactive ceramide, sphingosine and S1P When sphingomyelin ... activation, while HDL could inhibit all of these, by inhibiting the SPHK activity triggered by TNFα These findings suggested an atherogenic role for SPHK activation Interestingly, Nofer et al (2004) reported ... immunosuppressive effects of S1P by inhibiting proliferation and secretion of cytokines, while enhancing secretion of the suppressive cytokine Interleukin-10 (IL-10) S1PR5 is the most recent member in S1PRs family
Ngày tải lên: 11/09/2015, 16:06
The role of microRNAs in embryonic stem cell development and differentiation
... for indefinite self-renewal in culture 1.1.3 Maintaining Pluripotency: LIF, BMP & Wnt Signalling One of the major breakthroughs in ESC maintenance was reported in 1988, when leukemia inhibitory ... noncoding RNAs similar to the siRNAs involved in RNA silencing, originate from stem-loop precursors in the genome They have been shown to play important roles in diverse processes including apoptosis, ... microRNAs in animals However, it is interesting to note that other components of the post-transcriptional machinery, the RNA-binding proteins (RBPs), are known to bind all along mRNAs and regulate their
Ngày tải lên: 12/09/2015, 08:16
The role of people training and development in delivering service quality in uk based thai restaurants
... training for some employees (Hospitality Training Foundation, 1999) Bearing in mind the importance skill staffs in providing service quality in the hospitality sector, impacts of training in development ... Regarding to ethnic food history in the UK, Chinese and Indian cuisines have become dominant since the end of the 19th century with the first arrival of Chinese and Indian immigrants (Mintel, ... quality The following part declares the necessity of people training and development to improve staff skill in a context of less training practise in the hospitality due to unawareness of training
Ngày tải lên: 24/03/2021, 17:39
Impact of communication in agile development on the performance of engineers in semiconductor industry
... research is R&D engineers in the semiconductor industry.Research findingsThe findings of this study will assist management in selecting effective communication mediums to enhance engineers' performance ... and communication effectiveness refers to achieving the intended purpose of the communication in the best possible manner Effective communication is crucial in agile development, facilitating the ... thorough assessment of discriminant validity, addressing the limitations inherent in using Fornell-Larcker alone.After obtaining the outcomes of the measurement model, the structure of model is utilized
Ngày tải lên: 23/10/2023, 06:19
Circuit theory of finance and the role of incentives in financial sector reform
... capital profitability is declining. The internalization of information within the same institution may thus enhance intra-circuit and inter-circuit stability by reducing the incentive to overfinancing. The ... placing money with investment financial institutions in the capital market, and hold the remaining share in non- interest bearing, short-term bank deposits (eq. 7). The share of savings going ... Banks thus increase lending to the point where the marginal revenue from lending equals the marginal default risk. The amount lent determines the amount of inputs that firms can purchase in the factor...
Ngày tải lên: 24/10/2012, 09:33