tech transfer—from academia to commercialization

... all of which are cytotoxic towards the invading microbes As a strategy to evade the host immune attack, pathogenic microorganisms have evolved biochemical pathways to resist to such a stress condition ... (FlRd) belongs to the family of flavodiiron proteins (FDPs), microbial enzymes that are expressed to scavenge nitric oxide (NO) under anaerobic conditions To degrade NO, FlRd has to be reduced ... restricted group of pathogenic amitochondriate protozoa [12–14], are responsible for NO detoxification under anaerobic conditions [7,8], thus helping microbes to survive in NO-enriched microaerobic

Ngày tải lên: 16/03/2014, 11:20

... ta có thể tận dụng tối đa những lợi ích mà toàn cầu hóa và hội nhập kinh tế quốc tế mang lại Sau 30 năm đổi mới, Việt Nam đã đạt được nhiều thành tựu to lớn và quan trọng, làm cho thế và lực của ... Tiếp cận thị trường một cách toàn diện: Hiệp định TPP cắt giảm thuế quan và các hàng rào phi thuế về căn bản đối với tất cả thương mại hàng hóa và dịch vụ và điều chỉnh toàn bộ các lĩnh vực về thương ... kinh tế số và vai trò ngày càng tăng của các doanh nghiệp Nhà nước trong nền kinh tế toàn cầu - Bao hàm toàn bộ các yếu tố liên quan đến thương mại: Hiệp định TPP bao gồm các yếu tố mới được

Ngày tải lên: 26/06/2017, 20:33

... the life sciences called recombinant DNA technology was coupled with entrepreneur-ship into a start-up called Genentech Genentech eventually blossomed technological achievements are without question ... consolidation seen in this industry sector in recent decades (and continuing) can partly be attributed to this factor The purpose is to acquire patents with years to go before expiry and pipeline products ... life sciences equated to endeavors aimed at benefiting humans, i.e biomedical science To this end, a sizable financial investment was used to develop infrastructure primarily to house research institutes

Ngày tải lên: 05/01/2018, 17:22

... to six in 1984 and steadily to 36 issues by 2005 A biomaterials scientist has a lot more to read and evaluate in the year 2012 compared to 32 years before! To be up-to-date and comprehensive in ... OF “IVORY TOWER” TENANTS Before concluding the snapshot of academia, it is informative to be aware of how the outside world views academics that are sometimes referred to as Ivory Tower tenants ... prefer selling to academia Despite the bureaucratic process and frequent delays in payment, they know they will ultimately get paid, a plus compared to selling to the private sector where collection

Ngày tải lên: 05/01/2018, 17:22

... be selected to take into product development Academia is more flexible in resource utilization towards such exploratory efforts compared to industry There is one important detail to note using ... original design to solve a need she has but has not been satisfactorily addressed, you have a rare opportunity Your role as the sci-ence and technology component is to provide a technological solution ... AND TECHNOLOGy’s ROLE 47as the human body My first encounter with chitin was using a cal variant, chitosan, to assist a botany colleague to develop an artificial biomate-rial, I settled to investigating

Ngày tải lên: 05/01/2018, 17:22

... the product To be sure, the payoff is often significantly larger compared to a service company, but a product is a tougher bet to pull off, and therefore harder to obtain capital to start Contrast ... outfitter to a stampeder. Our strategy was to get to the point where we could generate enue and reinvest profits into R&D, and perhaps to pursue a device rev-A testing company would permit us to ... realized that we had to have more practice and fine-tune many of the things we wanted to do So what did we do? Our solution was to incubate, convince someone to allow us to set-up, and consolidate

Ngày tải lên: 05/01/2018, 17:22

... mind that you have to protect your own interests You must be aware of what you may have to give up to get on the fast track to market the service or product You do not want to end up just being ... also aware you have to rigorously think through the impact of reg-ulatory matters on your potential business You remain undeterred and are now eager to move forward to put a plan together But as ... cred-ibility gap and financial handicap compared to the big boys, much like the oft-told Bible story of David, the puny Bethlehemite teenager with a slingshot, a stone and no combat experience battling

Ngày tải lên: 05/01/2018, 17:22

... has to reflect your best effort This document speaks more about your character, your aspirations and what you plan to do to achieve than on the enterprise you plan to start If any-one cared to ... are reminded to be factual and respectful of your competitors If you have identified entry barriers that competitors and me-too fol-lowers will find difficult (never impossible) to overcome, ... about a BP to inscribe in your mind is no one needs to be impressed by your sizable curriculum vitae of scientific achievements and awards Potential funders are not agreeing to listen to your BP

Ngày tải lên: 05/01/2018, 17:22

... program to the approval for BRASS to start-up, took approximately 15 years to fulfill that I did not learn to fully appreciate until much later and after much reflection I was also able to persuade ... side is that you have to give some of your potential value to get the funds you require to start You will be very tempted to compro-mise your stake in the pie to get the funds to start operations ... about to get smaller; the banks are about lending to people who have money (since you are unlikely to have col-lateral and they usually lend up to only twice your monthly salary sub-ject to you

Ngày tải lên: 05/01/2018, 17:22

... with regulatory matters to: with regulatory matters to get your product through the regulatory submission and approval process you control your company’s purse strings Making a commitment to gain ... motivated to get on top of the testing component to move your regulatory paperwork along as they have access to their own tests experts This is a reasonable and efficient approach 8.2.1 Regulatory ... blood into color-coded vacutainers® and heads to the lab to assay the contents This is followed by the duty nurse inserting a couple more needles into your arm, connecting the hub ends to tubes

Ngày tải lên: 05/01/2018, 17:22

... has to be built to maintain the company’s momentum Your staff will need to convert from Jack & Jill of all trades to specialists A good business and/or HR consultant will assist you to achieve ... grow to a level that justifies the hire of a full-time staff to perform the consultant’s function It is best at that stage to hire a suitable person and have the consultant train the new hire to ... issues you have to consider with regard to the Trang 10consultants’ background and experience You have to be comfortable with what you eventually decide Category 2 consultants are easier to define

Ngày tải lên: 05/01/2018, 17:22

... available attention 10.2 PLAN TO ACHIEVE 100% – ESTABLISHING MILESTONES To plan, you need goals Your goal is for your first product to obtain regulatory approval in order to commence sales, or have ... 4operational to generate revenue You must plan to achieve this goal up to 100% completion A straightforward method is to first list down the important tasks that need to be completed to reach the ... Route Major milestone 1 Major milestone 3 Major milestone 4 Major milestone 5 Major milestone 6 FUNDS ALLOCATION $X1 $X2 $X3 $X4 $X5 $X6 FIGURE 10.2 Flowchart of major milestones with corresponding

Ngày tải lên: 05/01/2018, 17:22

... sub-contrac-tor to several clients Due to one of the quirks of the biomed industry, once a sub-contractor is qualified, changing to another sub-contractor i To this day, I remain indebted to these ... you had opted to develop, test and pass your prototype with a sub-contractor, this should be completed by the time your facility is ready If you had chosen to wait and develop the prototype in-house, ... take up to 18 to 24 months to achieve, after which your operations should settle down to a more rou-tine workflow At that stage, you probably will begin revising your oper-ational workflow to include

Ngày tải lên: 05/01/2018, 17:22

... These approaches to learning appear to be less common nowadays The trend is to pursue and finish study or training programs in the shortest time so as to begin employment The path to advancement ... others to form of you But you obtain the most information by reading extensively accord-ing to topics (breadth) as well as by specialization (depth) Hoard books and revisit them often Visitors to ... support staff, especially the surgical nurse-in-charge, have to be con-vinced as well If the packaging is too difficult to separate to access the device, troublesome assembly or user safety while

Ngày tải lên: 05/01/2018, 17:22

... related to the application as a potential heparin replacement exists However, extending to commercial exploitation as This is no way to treat yourself, your staff, clients and investors. chitosan. ... wait for-ever If it was never meant to be, it is best to realize sooner, pull the plug, and regroup to try a new endeavor (3) YOUR CUSTOMERS FOUND THE PRODUCT TOO COSTLY AND/OR THE PRODUCT UNDERPERFORMED. ... success 13.2 FROM START-UP TO PROFIT AND BEYOND In your action plan, you would have set the milestones you need to achieve along the way to success These are important to get your prod-uct manufactured,

Ngày tải lên: 05/01/2018, 17:22

... steadily from 41,000 tons in 1986, for example,  to 7.0 million tons in 1994, 7.7 million tons by  the end of 1995. In 1997, it has reached nearly  10 million tons Since there is no other actors in oil and gas  ... by Scottish Enterprises to Vietnam to do a high  profile   presentation   to   the   top   managers   of  PetroVietnam coming from all departments. By  introducing   company   A   to   Vietnam,   it ...   for   rather   productive  discussion on technical matters. But when it is  necessary to send top managers to discuss the  deal, the company fail to do. This is seen by  Vietnamese   partner

Ngày tải lên: 02/02/2020, 15:34

... steadily from 41,000 tons in 1986, for example, to 7.0 million tons in 1994, 7.7 million tons by the end of 1995 In 1997, it has reached nearly 10 million tons Since there is no other actors in oil and ... Australian office to visit Vietnam for rather productive discussion on technical matters But when it is necessary to send top managers to discuss the Trang 5deal, the company fail to do This is seen ... crucial factors to take into account if the transfer process is to be successful Do the home work carefully is a must for foreign companies to understand its future and present partners, to understand

Ngày tải lên: 19/10/2022, 14:03

... group to H-bond to the NADP+ pyrophosphate, providing the necessary flexibility to address the NMN moiety of NADP+ towards the active site [99,108,114] Finally, the Tyr at the si-face contributes to ... benzene ring towards the pyrazine ring, placing the accepted electron nearer to a site where it can best be neutralized by protonation – the N5 position Electron transfer from PSI to flavodoxin ... FAD cofactor of FNR has accepted two electrons, they have to be transferred to NADP+ The FNR protein portion has a dual role in this process by: (a) modulating the FAD midpoint potential to a value...

Ngày tải lên: 18/02/2014, 11:20

... a curriculum parallel to the Spanish one Fourth, all students in the study were exposed to the same literacy curriculum, Success for All (SFA)/Éxito para Todos (EPT).1 To ensure geographic diversity ... reading We hope to use this analytical technique to reexamine two other key research questions: (1) Does the effect of Spanish literacy on English literacy vary with respect to level of Spanish ... initial differences in factors that may predispose one group to better than another independently of language of literacy instruction Such factors include, but are not limited to, oral language proficiency,...

Ngày tải lên: 24/02/2014, 18:20

... trapped on each filter was used to calculate the wetting volume and was subtracted from the total Ca2+ bound to the filter, to give the specific amount of Ca2+ bound to the ATPase A correction was ... for the inhibitory phase of 0.35 ± 0.06 mM However, in the presence of 2-APB (800 lM), the Vmax was reduced to 5.9 ± 0.2 UÆmg)1, and stimulatory and inhibitory Km values increased to 0.90 ± 0.03 ... conformational changes associated with Ca2+ binding to the ATPase, tryptophan fluorescence was monitored in the absence and 45 Ca2+ binding to the ATPase To deduce whether 2-APB was directly affecting...

Ngày tải lên: 31/03/2014, 23:20