... collagen synthesis of lung fibroblasts The stimulatory effects of a-defensins on collagen synthesis reach a plateau at higher concentrations, whereas the proliferative effects are reduced The results ... a-defensins activate the b-catenin signaling pathway We then studied the role of the b-catenin signaling pathway in a-defensininduced increases in the proliferation and collagen synthesis of lung fibroblasts ... In the present study, we also found that a-defensin-1 and a-defensin-2 stimulated the proliferation and collagen synthesis of two other cell lines of lung fibroblasts (HFL-1 and LL86) However, the...
Ngày tải lên: 18/02/2014, 06:20
... localized to the amino-terminal loop and the three-turn a-helical region of human L-PGDS, respectively The previously generated MAb-1B7 [16] bound to the EF-loop on the side opposite the sites for ... exposed on the surface of the molecule However, in the soluble form, the affinities of MAb10A5 for native L-PGDS were lower than those for the recombinant protein, suggesting that the C-terminal ... much weaker staining in the tubules than that obtained with MAb-1B7 (Fig 3G, H) In the glomeruli, the mRNA and L-PGDS protein detected with MAb-5C11 were localized in the epithelial cells of Bowman’s...
Ngày tải lên: 30/03/2014, 01:20
IELTS writing - the editing process
... often mistakes happen because all the parts of the sentence are correct, but those parts of a sentence not fit together What to check for This is the big one There are a number of different items ... of them You need to make your own personal checklist before the exam: to this you need the assistance of a teacher to advise you of your mistakes See this exam tip for more detail Grammar The ... more complex ones, therefore you should check your basic grammar most carefully Verb tenses: make sure they are consistent and in task that your tenses match the time frame in the graph Articles:...
Ngày tải lên: 05/11/2012, 09:18
Developing Writing Skills in a Foreign Language via the Internet.doc
... all the points and details of the one subject Then the next section discusses and includes all the points and details of the other subject For example, if our writers are asked to compare the ... point in this task, the groups that were initially assigned to work together e-mailed their finished product to the other team Once again, after the information from the other team has been received, ... between the weather conditions of Paris, France, and Moscow, Russia Now, the paired up teams will collaborate to decide what three points they will include to write about in their essays The decision...
Ngày tải lên: 06/09/2013, 05:10
Correspondence for the Application Process and the Job Search
... twelve schools in the northeast due on our campus tomorrow, we should have a great career fair It was great seeing you and all the brothers at our alumni officers’ gathering at the University of ... Newspapers and the Associated Press My most recent publication is the second edition of my book, Technical Documentation on the Internet Correspondence for the Application Process and the Job Search ... will most likely appeal to the reader and include them, thus, effectively targeting your audiences’ expectations and needs The between -the- lines information represents the nuances of effective...
Ngày tải lên: 25/10/2013, 18:20
FOCUS ON - phrasal ver bs with the particle off and the adverb right
... are gathered together in a crowd to separate and leave the area, the police break the gathering up The meeting should break up around 3:00 The police ordered the gang members to break it up The ... separable phrasal verbs are in the passive, they cannot be separated by the object of the verb because the object of the active verb is the subject of the passive sentence — there is no object: active ... from one side to the other very quickly The receiver ran across the field and caught the ball It's crazy to run across the street through the traffic instead of waiting for the light run across...
Ngày tải lên: 01/11/2013, 12:20
A study on modal adjuncts in the mental process in english and vietnamese newspapers
... may lead the speaker to the situation of doubt and suspicion the badness or goodness about the state-of-affairs mentioned in the They may, they may not, they should certainly believe they proposition ... such as the Guardian, the BBC, the NYTimes, the Independent The data in Vietnamese are mainly taken from Vietnamese sports newspapers such as the Thanh Niên, the Lao Đ ng, the Nhân Dân, the Tu ... towards the desirable or undesirable aspects of the things presented in their claims and they use and distinguish MAs in the three-type MenP 5.3 LIMITATION OF THE THESIS AND FURTHER STUDY The study...
Ngày tải lên: 26/11/2013, 13:17
Tài liệu Customizing the Login Process docx
... message box containing the custom message text and an OK button will appear when the user logs on to the system The boot process will continue as usual after the user clicks the OK button You can ... you disable the Welcome screen, which by default, is enabled To disable the Windows XP Welcome screen, open the Control Panel window, start the User Accounts applet, click the Change the way users ... strengthen security When the standard Windows NT/2000/XP or Windows Server 2003 configuration is used, the system displays the name of the user who last successfully logged If you hide this name, the...
Ngày tải lên: 14/12/2013, 10:15
THE RECORDING PROCESS handout
... equation Chapter 2-3 Steps in the Steps in the Recording Recording Process Process Journal Ledger The Recording The Recording Process Process Illustrated Illustrated The Trial The Trial Balance Balance ... is and how it helps in the recording process Explain what a ledger is and how it helps in the recording process Explain what posting is and how it helps in the recording process Prepare a trial ... process Prepare a trial balance and explain its purposes Chapter 2-2 The Recording Process The Recording Process The Account The Account Debits and credits Debit and credit procedure Stockholders’...
Ngày tải lên: 15/12/2013, 20:27
Tài liệu Unit_5: The central processing unit pdf
... components The control unit directs the flow of information within the processor The arithmetic-logical unit of the processor is responsible for the interpretation of program instructions The arithmetic-logical ... III Locating information Find the passage in the text where the following ideas are expressed The processor is the control unit and the arithmetic-logical unit The processor operates on information ... internal storage The CPU directs all the activities of the computer The control unit coordinates the sequencing of events within the processor The word” computer” usually refers to the CPU plus internal...
Ngày tải lên: 21/12/2013, 20:15
Tài liệu Setting Up the Login Process doc
... enter their names and passwords (And how can they, since the Mac rushes right into the Automatic person's account at startup time? Answer: The Automatic thing happens only at startup time The usual ... restart simply by pulling the plug, then either use FileVault or set the Open Firmware password, as described in the box below • Show Input menu in login window If the Input menu (Section 9.13.3) ... on the machine, blowing right past all of the safeguards you've so carefully established One way to thwart them is to use FileVault (Section 12.9.2) Another is to turn off this checkbox Now there's...
Ngày tải lên: 26/01/2014, 06:20
A contrastive analysis of the meanings expressed via the modal verbs can, may, must in english and the equivalent expressions in vietnamese
... verbs Therefore, teachers should base themselves on the content of the lesson, the students level, the grammatical items they want to teach to find a suitable method by which they can achieve the ... about the truth or correctness of the information through the use of the modal must In the case of a question, the listeners opinion is involved, as well as the person obviously referred to by the ... realized by the subject of the sentence by the speaker (or by some other agents) In the epistemic world, the must in the same sentence could be read as a logical necessity according to the reasoning...
Ngày tải lên: 29/01/2014, 00:23
Tài liệu GUIDELINES FOR THE PRODUCTION, PROCESSING, LABELLING AND MARKETING OF ORGANICALLY PRODUCED FOODS docx
... or preserve the food, in the case of additives, or – produce the food, in the case of processing aids in the absence of other available technology that satisfies these Guidelines; – these substances ... deceived concerning the nature, substance and quality of the food; – the additives and processing aids not detract from the overall quality of the product In the evaluation process of substances ... those areas whenever the physiological condition of the animal, the weather conditions and the state of the ground permit 39 The competent authority may grant exceptions for : – the access of bulls...
Ngày tải lên: 14/02/2014, 03:20
Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... ER stress When the available acyl-CoAs are in excess, they are channeled towards TAG synthesis The main findings of the present investigation were the observations that TAG synthesis in liver ... periods Interestingly, the interruption of TAG synthesis preceded the appearance of toxic effects, supporting the notion that it constitutes the initiating event in the process of lipotoxicity ... into the TAG pool only in the presence of oleate [18] The above results raise two main questions: (a) what is the cause of TAG synthesis inhibition, and (b) what is the exact nature of the events...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: FOXM1c transactivates the human c-mycpromoter directly via the two TATA boxes P1 and P2 docx
... cofactors [38,49,50] TBP binds to the minor groove of the TATA box, thereby bending the DNA 80° towards the major groove, unwinding the DNA by 120° and kinking the TATA box at both ends by intercalation ... be explained by the direct interaction of the N-terminus (amino acids 1–194) with the TAD (amino acids 721–762) [30] Therefore, the N-terminus as NRD represses transactivation of the P1 and P2 ... promoters by directly binding to the TAD In summary, the forkhead domain (i.e the DBD) TAD and N-terminus, have the same functions for transactivation of the c-myc promoter via its TATA boxes and for...
Ngày tải lên: 19/02/2014, 05:20