specifying workflows with activity diagrams

... associated with a decline in physical health Among the elderly, those with activity limitations are substantially less healthy than the general population Well over half of the populations with an ... used by caregivers to cope with such strains are prayer (74 percent) and talking with relatives and friends (66 percent).1 FIGURE Amount of Help for People 70+ with Activity Limitations 14% 7% ... people age 70 and older with activity limitations is expected to increase substantially over the next several decades as the number of elderly increases If the current rate of activity limitation...

Ngày tải lên: 14/02/2014, 06:20

... binding on enzyme activity, we tested the catalytic activity of mIGPS in the presence of this ligand A plot of the ligand concentrations against mIGPS activity (Fig 6A) showed that the activity decreased ... ˚ ATB107 within a distance of A Ten of them were mutated to alanine, with a methyl group side chain, 148 Fig Effect of ATB107 binding on mIGPS activity ATB107 inhibited mIGPS enzyme activity ... isoniazid and rifampin) M tuberculosis, with M tuberculosis H37Rv as a control Effect of ATB107 on mIGPS activity in vitro The concentration of mIGPS was determined with the Bradford method, using the...

Ngày tải lên: 07/03/2014, 03:20

...  Connecting the goal model with other system views  Capturing alternative options  Goal diagrams as AND/OR graphs  Documenting goal refinements & assignments with annotations  Building goal ...  Connecting the goal model with other system views  Capturing alternative options  Goal diagrams as AND/OR graphs  Documenting goal refinements & assignments with annotations  Building goal ...  Connecting the goal model with other system views  Capturing alternative options  Goal diagrams as AND/OR graphs  Documenting goal refinements & assignments with annotations  Building goal...

Ngày tải lên: 13/07/2014, 07:20

... feature with same name within specialized SubOb (“override”) www.wileyeurope com/college/van lamsweerde Chap.10: Modeling Conceptual Objects © 2009 John Wiley and Sons 26 Object specialization with ... class diagram – “objects”, classes not in the OO design sense: RE is concerned with the problem world only ! – classes with no operations: data encapsulation is a design concern; no design decisions ... classes & current instances  (2) Every concept in object model must be defined by Def annotation specifying the necessary & sufficient condition for an individual to satisfy InstanceOf (o, Ob)...

Ngày tải lên: 13/07/2014, 07:20

... lớp Activity Diagram: Car Sale Process Initial Initial State State Control Control Flow Flow Decision Decision Fork Transition Fork Transition Note Note Action State Action State (Activity) (Activity) ...

Ngày tải lên: 24/07/2014, 12:20

... 8 CHAPTER Activity Diagrams This chapter focuses on activity diagrams, which depict the activities and responsibilities of elements that make up a system First, I introduce activity diagrams and ... Many details of activity diagrams that were not fleshed out in Chapter are more fully elaborated here, and throughout the chapter, I include suggestions relating to activity diagrams Activity modeling ... Collaboration Diagrams 121 Roles Messages and Stimuli Interactions and Collaborations Sequence Diagrams Collaboration Diagrams Exercises 122 128 128 129 138 143 State Diagrams...

Ngày tải lên: 22/10/2014, 21:50

... blood and serum antioxidative activity (CAT, GSHpx) and the mean blood and serum MDA and MPO values (oxidative activity) , between the patients with anti-CCP(+) and those with anti-CCP(-) (Table 2) ... positivity seems to be associated with increased synovial fluid oxidant activity (increased MDA and MPO levels) in patients with RA And this increased oxidative activity in synovial fluid may be ... synovial fluid, there was increased synovial oxidant activity (MPO and MDA levels) (p

Ngày tải lên: 25/10/2012, 11:15

... serum total cholesterol concentrations are clearly associated with those of aspirin esterase activity during a period of physical activity modification in an older population This finding suggests ... whole circulating aspirin esterase activity as compared to that of BChE (8), and our study population did not include subjects with malnutrition nor there were any with nutritional modifications ... association of changes in circulating total cholesterol with those of serum aspirin esterase activity in an older population that participated in a physical activity modification program Although aspirin...

Ngày tải lên: 26/10/2012, 09:39

... 94 Activity 11.1: Experience with User Interfaces Exercise 1: Identify characteristics of user interfaces ! Identify...

Ngày tải lên: 17/01/2014, 09:20

... correction) 1.2 With minimal findings 1.3 With clinically significant findings 1.4 After palliative interventions: 1.4a 1.4b Group With seperation of the circulations (e.g., Fontan procedure) Without ... recommendations on types of sport suitable for all persons with congenital heart disease (e1, 8, e5, 9, 11, 12, 13, e8, e9, 17) Physical activity in children with congenital heart disease should start as ... changes Group Patients with inoperable cardiac defects Group Patients with chronic myocardial disorders 4.1 Clinically significant 4.2 Clinically insignificant Group Patients with problematic long...

Ngày tải lên: 12/02/2014, 19:20

... develop an APC molecule with enhanced anticoagulant activity with the purpose of investigating the effect of APCs with increased anticoagulant activity in vivo on different thromboembolic diseases ... increased binding sites with enhanced affinity (Fig 3D,E and Table 1) For example, mutant II binds to 0-10-90 with KD = 2.45 lm ⁄ Rmax = 3005 RU, whereas binding to 0-20-80 is improved with KD = 0.66 lm ... not shown) Mouse APC variants with hyper-anticoagulant activity in mouse plasma The generation of thrombin is severely diminished in mouse plasma when an APC variant with high affinity for membranes...

Ngày tải lên: 18/02/2014, 06:20

... Expression and solubilization of recombinant RPE65 with isomerohydrolase activity To optimize the expression of chicken RPE65, 293ALRAT cells were infected with different titers of adenovirus expressing ... enzymatic activity of RPE65 For these measurements, a novel enzymatic activity FEBS Journal 276 (2009) 3020–3030 ª 2009 The Authors Journal compilation ª 2009 FEBS 3021 Isomerohydrolase activity ... blotted with antibody against RPE65 (D, E) The effect of Chaps concentration on the isomerohydrolase activity of RPE65 was evaluated using in vitro isomerohydrolase assays Liposomes preloaded with...

Ngày tải lên: 18/02/2014, 08:20

... synthetic compounds with glutathione peroxidase activity J Am Chem Soc 111, 5936 5939 12 Iwaoka M & Tomoda S (1994) A model study on the effect of an amino group on the antioxidant activity of glutathione ... to help stabilize the selenolate and enhance the GPX-like activity of diselenides [11] Although some GPX mimics show some increased activity, most show only limited catalytic enhancement Based ... 6-CySeCD displays GPX activity S.-W Lv et al Table Comparison between GPX activities of the 6-CySeCD-catalyzed reduction of hydroperoxides by GSH and other species One unit of enzyme activity is dened...

Ngày tải lên: 19/02/2014, 02:20

... prodomain are designated with the suffix ‘p’) and a catalytic domain (Ala1-Pro364; residues in the mature catalytic domain are numbered without a suffix where unambiguous, and with the suffix ‘e’ otherwise) ... showed a bell-shaped profile with apparent pKa values of 3.8 and 5.8, whereas the logkcat vs pH profile displayed a profile with slope ¼ )1 which leveled off at low pH values with an apparent pKa of ... been equilibrated with mm KH2PO4 ⁄ acetate buffer, pH 4.3 After extensive washing of the column with the equilibration buffer, the 38-kDa mature form of the mutant was eluted with a linear gradient...

Ngày tải lên: 19/02/2014, 07:20

... filters with anti-Ras (D) and with anti-Erk (E) antibodies ogy, concomitant with a disruption of actin microfilaments, and ultimately cell death (compare Fig 4B with 4F), corroborating with earlier ... precleared with GST beads prior to 1-h incubation with each of the indicated GST-ExoSfusion proteins Samples were subsequently washed and run on SDS ⁄ PAGE, followed by immunoblotting with 14-3-3 ... our pull-down analysis with GST-ExoS(LDL426– 428AAA) still strongly suggests that ExoS must utilize a strategy for its interaction with 14-3-3 that is similar to that seen with R18 and serotonin...

Ngày tải lên: 19/02/2014, 08:20

... cells with galactose, there was 3.5-fold increase in epimerase activity (Fig 4B) while the constitutive mutarotase activity remained the same More importantly, with the increase in epimerase activity, ... epimerase activity also showed mutarotase activity If S cerevisiae epimerase were a truly bifunctional enzyme, then induction with galactose should induce both epimerase and mutarotase activity ... (ORFs) YHR210c and YNR071c, with putative aldose 1-epimerase activity These ORFs encode for proteins, each with a predicted molecular mass of 38-kDa, and exhibit 99% identity with the human aldose...

Ngày tải lên: 19/02/2014, 12:20

... formation is lower in the presence of the antibody, with a decrease in the rate constant of  7% being observed with hydroxylamine and of > 40% with the more bulky hydroxylamine The amount of Fe(II)–RNO ... complex (C50), with either MP8 or 3A3-MP8 (Fig 1, Table 1) Second, with both hydroxylamines, a decrease in the reaction rate, as well as an increase in the C50 value, are observed with the 3A3– ... products were then extracted with CH3COOEt and analyzed by GC The only product formed, with a 2.5% yield, was the corresponding sulfoxide that was identified by comparison with an authentic sample...

Ngày tải lên: 19/02/2014, 12:20

... subsequently collected KIPase activity was measured using the in vitro fluorogenic assay with Ac-DPSD-AMC as substrate, as described above Results We previously identified KIPase activity in the transformed ... KIPase activity, whereas the aldehyde-modified form of ESQD displayed no inhibition of KIPase activity for either cell type These data showed that DPSD-CHO is an efficient inhibitor of KIPase activity; ... presented together with the standard deviation Fig DPSD-CHO does not inhibit the in vitro activity of known human caspases (A) The indicated human recombinant caspases were each assayed with their optimal...

Ngày tải lên: 19/02/2014, 13:20

... retrieve texts whose own metaphors are consonant with those of the searcher, and which elaborate upon the same talking points This requires a computer ... the construction of our lexicon of affective stereotypes in section Each stereotype is associated with a set of typical properties and behaviors (like sprawling for giant, or inspiring for guru), ... use a wildcard * in both positions (ADJ and NOUN, or VERB and NOUN), which yields limited results with a search engine like Google, we generate fully instantiated similes from hypotheses generated...

Ngày tải lên: 19/02/2014, 20:20