sleep deprivation and sleep disorders

... orders@intechweb.org Sleep Disorders, Edited by Chris Idzikowski p cm ISBN 978-953-51-0293-9 Trang 5Contents Preface IX Chapter 1 Sleep and Pregnancy: Sleep Deprivation, Sleep Disturbed Breathing and Sleep Disorders ... welcome and are discussed by Dr Miyamoto Chris Idzikowski Director, Edinburgh Sleep Centre and the Sleep Assessment and Advisory Service, Edinburgh, UK Trang 13Sleep and Pregnancy: Sleep Deprivation, ... more awakenings and had had poorer sleep efficiency They had less stage 4 sleep and more stage 1 sleep and spent less time in rapid eye movement (REM) sleep (Wilson et al, 2010) Sleep quality

Ngày tải lên: 17/03/2014, 02:20

... on sleep Aspirin and ibuprofen in Disrupts sleep architecture healthy subjects Increases sleep latency Increases nonrapid eye movement (NREM) stage 2 sleep Increases slow-wave sleep Decreases sleep ... Roth T, and Dement WC Principles and Practice of Sleep Medicine Philadelphia: Elsevier/Saunders 2005 (3) Pagel JF Medications effects on sleep In: Attanasio R and Bailey DR, eds Sleep Disorders: ... Decreases sleep latency (Note: good long-term sleep aid) Benzodiazepines Decreases sleep latency Increases NREM stages 1 and 2 Increases total sleep time Decreases slow-wave restorative sleep Decreases

Ngày tải lên: 21/01/2020, 19:31

... Mark B and Dement W: The Task-force 2000 survey on medical education in sleep and sleep disorders Sleep 1998, 21:235-238. 23. Namen AM, Wymer A, Case D and Haponik EF: Performance of sleep histories ... Schwartz AR and Smith PL: Sleep-disordered breathing and insulin resistance in middle-aged and overweight men Am J Respir Crit Care Med 2002, 165:677-682. 12. Hermann DM and Bassetti CL: Sleep-disordered ... 2002, 159:855-857. 9. Rains JC and Penzien DB: Chronic headache and sleep disturbance Curr Pain Headache Rep 2002, 6:498-504. 10. Kumar S, Bhatia M and Behari M: Sleep disorders in Parkinson's disease

Ngày tải lên: 01/11/2022, 08:57

... 41 Susan Lindquist and Karen L Allendoerfer Tau and Intracellular Transport in Neurons 59 E.-M Mandelkow, E Thies, S Konzack, and E Mandelkow Signaling Between Synapse and Nucleus During Synaptic ... neurodegenerative disorders, isthat protein misfolding plays a defining role This was the focus of work reported byLindquist, in studies of Parkinson and Huntington disease models, and Mandelkowand colleagues ... Aβgeneration; and (4) sorting of APP and/or itsα- and β-carboxyl-terminal fragments (C83 and C99, respectively) toward the trans-Golgi network is under the influence of presenilins and the VPS35/retromer

Ngày tải lên: 14/02/2014, 17:20

... SMOKING: LUNG CANCER AND OTHER DISORDERS Major funding for this report has been provided by the Indoor Air Division, Office of Atmospheric and Indoor Air Programs Office of Health and Environmental ... PASSIVE SMOKING AND ACUTE AND CHRONIC MIDDLE EAR DISEASES 7-21 7.4.1 Recent Studies on Acute and Chronic Middle Ear Diseases 7-22 Trang 6CONTENTS (continued)vi 7.4.2 Summary and Discussion ... COUGH, PHLEGM, AND WHEEZING 7-30 7.5.1 Recent Studies on the Effect of Passive Smoking on Cough, Phlegm, and Wheezing 7-30 7.5.2 Summary and Discussion on Cough, Phlegm, and Wheezing

Ngày tải lên: 15/03/2014, 01:20

... space(sector and state) and gender and try to map how much it vary in relative terms It further looks up on correlates and determines of old age deprivation in India Trang 3Deprivation and vulnerability ... most of developing countries the older people and dependent are poor and vulnerable (world Bank 1994) The linkage between ageing and poverty and deprivation can have three channels of relations ... of economic, health and social aspects of deprivation among the elderly in India Old age deprivation in India The elderly in India often end up in a state of deprivation and negligence as there

Ngày tải lên: 22/03/2014, 13:20

... Trang 2ALZHEIMER’S DISEASE AND RELATED DISORDERS ANNUAL Trang 4ALZHEIMER’S DISEASE AND RELATED DISORDERS ANNUAL Edited by Professor and Director Alzheimer’s Disease Research Unit ... of A β40and A β42Neocortical tissue obtained postmortem from subjects selected from theJewish Home and Hospital in New York was examined for soluble and insolu-ble Aβ40and Aβ42levels and revealed ... in-vivolipid peroxidation (and thus of degree of oxidative stress), are elevated inurine, blood, and CSF in AD, and correlate with cognitive and functionalscores as well as CSF tau and amyloid concentrations.65To

Ngày tải lên: 28/03/2014, 22:21

... clinical features and treatment of Parkinson’s disease, followed by discussion of associated depressive disorders, anxiety, phobias, apathy, hallucinations, delusions and sleep disorders Speci ... an ‘‘understandable’’ consequence of the illness On theother hand, behavioral problems such as delusions and hallucinationsdramatically aVect both patients’ and caregivers’ lives, and treatment ... are also discussed, and the mechanisms for these disorders explored In addition, the book addresses the psychiatric and cognitive side-eVects of antiparkinsonian medications and new surgical treatments.

Ngày tải lên: 28/03/2014, 22:21

... 1Somatoform and Factitious DisordersTrang 2Review of Psychiatry SeriesJohn M Oldham, M.D.Michelle B Riba, M.D., M.S Series Editors Trang 3No 3Washington, DC London, England Somatoform and Factitious Disorders ... drug dosages, schedules, and routes of administration is accurate asof the time of publication and consistent with standards set by the U.S Food and Drug Administration and the general medical ... many mysteries of these disorders Despite the consistent richness of their historical and clinicaltradition, somatoform and factitious disorders have receivedvariable, and in some cases limited,

Ngày tải lên: 11/04/2014, 07:11

... Trang 2Psychological DisordersChild Abuse and Stress Disorders Trang 3Addiction Alzheimer’s Disease and Other Dementias Trang 4Foreword byPat Levitt, Ph.D. Vanderbilt Kennedy Center for ... psychological disorders later in life func-Those who study the relationship between brain ture and function, and the diseases that affect this bond, areneuroscientists Those who study and treat the disorders ... built and modified on a daily basmid-is, even during sleep.While there are thousands of chemical building blocks,such as proteins, lipids, and carbohydrates, that are used,much like bricks and

Ngày tải lên: 03/05/2014, 18:12

... obsessive-compulsive disorder (OCD) and obsessive-compulsive related disorders (OCRDs) and their clinical management via literature review, critical analysis and synthesis Information on OCD and OCRD current nosography, ... gambling, skin picking and others) and the tic disorders (for exam-ple, Tourette's syndrome) but others, including drug-induced and non-psychiatric disorders, could overlap and show similar clinical pictures ... symptom clusters for OCD and OCRDs: a 'somatic' cluster for BDD and hypocondriasis, a 'reward deficiency' cluster for TTM and other impulse control disorders (ICDs), and an 'impulsivity' one

Ngày tải lên: 08/08/2014, 23:21

... 12 As this patient repetitively clenches and unclenches his fists, a paucity of movement is apparent in his left hand Figure 13 Power-spectrum (upper) and accelerometer (lower) tracings taken ... normal) arcuate zone (white arrow), and rarefied pale-staining deep white matter, containing thick-walled arteriosclerotic blood vessels lying in dilated and fibrotic perivascular spaces (black ... lacunar infarct (pale area) with an irregular cavity lined by reactive cells (astrocytes and macrophages). Debris and a few vascular channels can be seen (Luxol fast blue–H & E) ©2004 CRC Press

Ngày tải lên: 09/08/2014, 16:21

... showing sym-metrical atrophy and discoloration of the putamen Figure 32 C-raclopride binding in a normal subject (left) compared with that in Parkinson's disease (middle) and in progressive supranuclear ... striatonigral degeneration shows atrophy of the putamen with rarefaction and gliosis (H & E) Trang 4Figure 36 Axial (upper) and coronal(lower) T2-weighted MRIs showing putaminal hypointensity ... arrow) and cerebellar (white arrow) atrophy in a patient with olivopontocerebellar atrophy Trang 9Figure 42 T2-weighted MRI (upper) shows hyperintensity of the middle cere-bellar peduncles and the

Ngày tải lên: 09/08/2014, 16:21

... degeneration shows severe gliosis and an achromatic neuron (H & E) Trang 3Figure 48 Dorsal (left) and palmar (right) views of dystonic posturing of the lefthand of a patient with corticobasal ... This patient with corticobasal degener-ation shows ideomotor apraxia of the left hand When asked to copy three hand postures (A–C, lower), in each instance, the patient's version was defective ... Dystonic postur-ing of the hand consequent to perinatal hypoxia Figure 58 Dystonic postur-ing of the foot consequent to perinatal hypoxia There is inversion of the foot and relative dorsiflexion

Ngày tải lên: 09/08/2014, 16:21

... cau-date nucleus (white arrow) and putamen (black arrow) Trang 9Figure 73 PETscans showing integrated C-raclopride and C-SCH 23390 activityin a normal subject (left) and choreic patient (right) ... indicate trinucleo-tide repeats of between 40 and 52 Trang 6Figure 69 Histological section of brain inHuntington's disease shows atrophy with loss of neurons and astrocytic gliosis (immunocytochem-istry ... Coronal section of brain in Huntington's disease shows symmetrical atrophy and brown discoloration (arrowed) of the caudate and putamen together with dilatation of the lateral vent-ricles Trang 7Figure

Ngày tải lên: 09/08/2014, 16:21

... obesity and type 2 diabetes (see Chapter 19) [46,47] Some possible reasons for high rates of obesity and type 2 diabetes in contemporary affluent societies (‘east’ and ‘west’, ‘north’ and ‘south’), and ... Hopkins University, 720 Rutland Avenue, Baltimore, MD 21205, USA Keith D Lindor Professor of Medicine, Mayo Medical School, andHead and Consultant, Division of Gastroenterologyand Hepatology, Mayo Clinic ... Trang 2Fatty Liver Disease: NASH and Related DisordersTrang 3Fatty Liver Disease: NASH and Related Disorders Edited by Geoffrey C Farrell Director, Storr Liver Unit,

Ngày tải lên: 10/08/2014, 15:20

... glucose and lipid metabolism,which explains the link with the associated metabolicdisorders In the scenario of metabolic and liver dis-ease, NAFLD looks very much like type 2 diabetes and obesity, ... associations will greatly enhance our understand-ing of disease pathogenesis and, accordunderstand-ingly, our abil-ity to design effective therapies Introduction Obesity and insulin resistance are undoubtedly ... production, TNF-α expression and insulin resist-ance, and ultimately to hepatocyte death and associ-ated inflammation The upregulation of uncouplingprotein-2 (UCP-2) by ROS, FFA and TNF-α alongwith dicarboxylic

Ngày tải lên: 10/08/2014, 15:20

... upregulated CYP2E1 and 4A MCD fed rats and mice Oxidative stress; upregulated CYP2E1 and/or 4A; ?secondary mitochondrial injury Fibrogenesis MCD fed rats and mice Roles of oxidative stress and stellate ... metabolism and the mechanisms of steatosis and lipotoxicity 2 The concept of fatty acid overload and the molecular and biochemical adaptive responses in the liver to fatty acid overload 3 The value and ... hypertriglyceri-daemia, increased FFA and steatosis [64] Among several other ko mice created in attempts to under-stand the pathogenesis and pathobiology of insulinresistance and type 2 diabetes (reviewed

Ngày tải lên: 10/08/2014, 15:20

... (see Chapters 7, 8 and 10) 3 Dysregulation of leptin expression and signalling 4 PPARα and γ expression and signalling 5 Inflammation and release of cytokine and other fibrogenic ... CYP2E1 and 4A or from other sources, dysregulation of leptin expression and signalling, peroxisome proliferator-activated receptor-α and - expression and signalling, inflammation and ... NASH and Related Disorders Edited by Geoffrey C. Farrell, Jacob George, Pauline de la M. Hall, Arthur J. McCullough Copyright © 2005 Blackwell Publishing Ltd MITOCHONDRIAL INJURY AND NASH 133 and

Ngày tải lên: 10/08/2014, 15:20

... aggressively and perform a liver biopsy, or take a more conservative approach and defer the liver biopsy and treat with current standard therapy for the associated comorbid associated metabolic disorders ... polyunsaturated fatty acids, fibre and the antioxidant vitamins C and E Inter-estingly, this study also showed that the NASH cohort had higher postprandial total triglyceride and very-low-density lipoprotein ... features of NASH and those with ‘bland’ cirrhosis We reported on a series of 70 consecutive patients with cryptogenic cirrhosis including both transplant and non-transplant candidates [44] Among

Ngày tải lên: 10/08/2014, 15:20