risks associated with the development of cervical cancer

... investigate whether expression of carbonic anhydrase XII (CA12) is associated with histologic grade of the tumors and radiotherapy outcomes of the patients with invasive cervical cancer Methods: ... Immunohistochemical expression of CA12 was highly associated with the histologic grade of cervical cancer Lack of CA12 expression was associated with PD histology, with an odds ratio of 3.9 (P = 0.01) Microarray ... strongly associated with histologic grades of the cervical cancer As CA12 and histologic grade were significantly associated with each other, we then examined whether an application of combined

Ngày tải lên: 09/08/2014, 09:20

... in relation with the development of sepsis This is the first study in trauma patients showing a link between the lack of immune recovery and the development of sepsis on the basis of the standardized ... the incidence of severe brain injury There were no statistical differences of the ISS or the incidence of severe thoracic injury between the two groups In the emergency room, administration of ... slope of mHLA-DR of less than 1.2 was independently associated with the risk of devel-oping sepsis, a finding that reflects the possible pivotal role of immune dysfunction in the increased risk of

Ngày tải lên: 14/08/2014, 07:21

... messages  Lymphocyte activity within 2 h of injury is associated with the development of MODS and lymphopenia after trauma  Development of MODS is associated with high NK dim cells and lowγδ-low ... London E1 2AT, UK Full list of author information is available at the end of the article © 2016 The Author(s) Open Access This article is distributed under the terms of the Creative Commons Attribution ... products [10] The lymphocyte count experiment included patients ad-mitted to the ICU to enable assessment of the significance of the lymphocyte count in the patient population at risk of MODS Data

Ngày tải lên: 24/11/2022, 17:40

... genotype of the tagSNP rs2282151, the expression levels of HSP90AB1, and the risk of CRC As shown in Fig 3, the C allele of rs2282151 was associated with increased risk of CRC Meanwhile, the C allele ... indicated the activity of the transcription All these five candidate causal SNPs were located in the peak of H3K27Ac Notably, the polymorphisms of rs10948128 and rs3757283 (two of the five SNPs) ... of the population of Mainland China and about 18 % of the entire global human population We investigated 23 tagSNPs in six genes in the inflammation pathway for their associa-tions with CRC The

Ngày tải lên: 20/09/2020, 18:20

... 10SUSD4 isoform based on the different molecularweight of the proteins It is possible that the impaired detection of wild type SUSD4b is caused by a differ-ent folding of the protein devoid of the ... reducing conditions The gel was blot-ted and the membrane was stained as described above After development of the SUSD4a signal, the lower part of the blot was washed and stained for the loading con-trol ... carcinoma-associated fibroblasts Furthermore, large numbers of SUSD4-expressing T cells in the tumor stroma associated with better overall survival of the breast cancer patients Conclusion: Our findings

Ngày tải lên: 22/09/2020, 23:51

... investigated the correlation of hTERT expression with survival and examined the possible role of TGFBR2 in the diagnosis and prognosis of cervical cancer We also tested whether the dual TGFBR2/ ... the members of the TGF-β /Smad pathway, is a cancer suppressor Underexpression or mutation of TGFBR2 is found in a number of cancers except cervical cancer16 TGFBR2 down-regulation promotes the ... increased, the incidence of cervical cancer remains high Thus, discovering reliable biomarkers is crucial for the development of potential therapeutic strategy for treating cervical cancer Telomere

Ngày tải lên: 19/11/2022, 11:48

... raise the question of why expression of only the basal subtype of breast cancer shows increased HERV-K expression A related question is the role of HERV-K in the etiology of basal breast cancer ... the leading cause of cancer death among women aged 20 to 591 To explore the molecular profiles of breast cancer, The Cancer Genome Atlas (TCGA) Network used an extensive set of technology plat-forms, ... nomenclature4 About 75–80% of TNBCs, defined by lack of expression of ER and PR and lack of overexpres-sion of Her2, belong to the basal subtype Basal breast cancer is one of the most virulent and

Ngày tải lên: 24/11/2022, 17:51

... for the colonization of broiler flocks with Campylo-bacter Farm-level factors associated with an increased risk of colonization include: the presence of other animals on the farm [13,20-23]; the ... on the farm Protective factors included the use of official or official treated water on the farm compared to the use of non-official untreated water, storing manure on the farm at any time of ... (i.e the practice of shipping all flocks on the farm within the span of a few days, with all houses remaining empty for a period of time) was not a significant predictor in any of the models The

Ngày tải lên: 12/08/2014, 18:22

... important to reflect These included the cost of laboratory processing of cervical samples; the cost of transporting cervical samples from clinical sites to the laboratory; and the value of patient time ... for the five countries of interest [31] To estimate facilities costs we compared the ratio of general per-meter facilities costs in each of the five countries with those of the US and used these ... generalize These included: (1) costs associated with laboratory processing of samples for either cervical cytology or HPV DNA testing using Hybrid Capture 2; (2) costs associated with transporting

Ngày tải lên: 13/08/2014, 11:22

... place in the leu operon of the ancestor of the two strains and dis-rupted leuA and the upstream region of leuB All sequences of the leu operon are still present in the genome of LVS, but they are ... lines represent the location of the IS elements in the compared genomes The breakpoints of the syntenic blocks in the subspecies holarctica and tularensis are often associated with IS elements, ... based on the annota-tion of their funcannota-tional counterpart in the genome of U112 For example, 41.2% of the genes predicted to be involved in amino acid biosynthesis in the genome of novicida

Ngày tải lên: 14/08/2014, 07:21

... of team selling They often lower the value of professional sales and does not properly understand the Vendor This is the wrong point The role of vendors is very large Besides, the vendors who ... sales, they also transmit the image and the face of the business Along with the development of information technology terminology auto sales (sales force automation) sales activities via the Internet, ... adapt the company to study how the quality of competing products instead Thereby determining the requirements for quality and design-oriented quality management in the process of manufacturing the

Ngày tải lên: 21/06/2015, 18:48

... needs of the great majority of visitors and residents In the future, the direction of Hanoi is towards the optimization of the exploitation of valuable natural resources including the enrichment of ... perception of both the accountants and the managers on the level of their awareness and understanding, ease of use, and the usefulness of the cost accounting system It further examined their attitude ... To determine the profile of the respondents in terms of gender, age, position and field of specialization 2 To describe the accountants’ and the managers’ perception of their level of awareness

Ngày tải lên: 20/09/2017, 16:53

... supported this hypothesis They showed that HCV infection reduces the QoL independently of the presence of comorbidities One of the factors found was the viral replication within the central nervous ... analysis of factors associated with SF 53 Table 27: Multivariate analysis of factors associated with RE 54 Table 28: Multivariate analysis of factors associated with MH 55 Table 29: Summary of association ... distributions Their score was therefore dichotomized using the mean as a cut-off point with one exception For the Role Emotional dimensions, the score of 100 was used as the cut-off point because

Ngày tải lên: 16/12/2018, 13:49

... con-verting the two correlations to z-scores, dividing the dif-ference between the z-scores with the standard error of difference between the two correlations, and then testing the significance of the ... that the same be-haviors can be studied from the perspectives of both ag-gressor and victim A further rationale for the development of the instru-ment was to facilitate the truthful report of aggressive ... questions on the theme “How are you treated by others?”, half of which refer to being the object of others’ aggressive behaviors, and half to being the object of prosocial behaviors from others Part

Ngày tải lên: 10/01/2020, 13:25

... compare the prevalence of unprotected water and piped water with that of protected water, and the prevalence of flush toilets and no facility sources with that of pit latrine toilets among the total ... were excluded if there was no data or ambiguous data on their WS use (these variables in the DHS and MIS were always represented in the form of ‘‘do not know” or ‘‘others”) or if their age was over ... tests were used for assessing the differences in the proportion of children with a ‘‘poor” socioeconomic status among the various WS conditions The P-values of all thev2 tests in Fig 2 were less

Ngày tải lên: 14/01/2020, 19:44

... the development of cervical cancer However, there are many discrepancies among the results obtained from the previous high-throughput studies of CNVs Therefore, it is necessary to validate these ... amplifications of MIR30D gene and miR-30d up-regulation in CSCCs Gene CNVs are frequently associated with the quanti-tative as well as functional shift of their gene prod-ucts We then tested whether the ... in ac-cordance with the manufacturer’s instruction of the Axy-Prep™ Blood Total RNA MiniPrep Kit (Axygen) Then the first-strand cDNA was synthesized by reverse tran-scription with the RevertAid™

Ngày tải lên: 19/09/2020, 21:35

... systems to assess the expression of the COX-2 protein both in the cancer epi-thelial cells and in the stroma within the same set of breast cancer samples Methods Patient material The material for ... by the authors to the sensitivity of the Ab2 antibody used in their study To the best of our knowledge only two groups carried out studies of the prognostic value of the COX-2 expres-sion in the ... Examination of cells of the tumour stroma demon-strated the prognostic value of COX-2 expression inde-pendently of the antibodies used in the experiments The only exception were some of the results

Ngày tải lên: 14/10/2020, 16:20

... interaction between them on the dis-tribution of breast cancer prognostic features (Table 4) The results indicate a significantly protective effect of the Lys allele on the proportion of the worse lymph ... corroborate the notion of reduced signa-ling with the variant EGFR isoform [13], leading to lower invasiveness, which reinforce the role of EGFR in breast cancer pathogenesis The interaction between the ... depends on the number of variant Lys alleles (Ptrend= 0.001) Similarly, Figure 3B shows the impact of the number of variant (CA) n alleles on the proportion of negative PR status The re-sults

Ngày tải lên: 05/11/2020, 00:47

... others, miR-18 which is intimately associated with the occurrence and progression of different types of cancer have also been implicated [16] In other research, miRNA expression profile was associated ... implication of miRNAs deregulation in the development of liver cancer As a part of this process, we profiled miRNA expression according to the degree of histological differentiation of HCC, and ... a deeper understanding of hepatocarcinogenesis [3,4], the molecu-lar pathogenesis of HCC remains rather unclear Indeed, the clinical heterogeneity of HCC and the lack of good diagnostic markers

Ngày tải lên: 05/11/2020, 07:17

... 1.96, therefore, it cannot reject the null hypothesis It rejects the alternative hypothesis because the z score is in range of the null hypothesis Part B Based on the profile analysis combined with ... Out of that, if the crisis occurs, the population size and the percentage of level of confidence will remain the same Therefore, the crisis will change the CI primarily through a change of sample ... will cause the value of the investment to fluctuate, thereby changing the standard deviation of the investment, ultimately promoting the change of the CI Question 10 In this study, it hypothesizes

Ngày tải lên: 09/05/2022, 20:33