... liposome-in-gel composites containing this drug for local bladder cancer treatment, and nanohydrogels delivering the taxane along with prednisolone for prostate cancer and inflammatory carci-noma applications ... cells/ml), grown for 24 h for attachment, and cultured with HGG samples that were allowed to gel for 90 min (23.1 % [v/v], pre-viously sterilized by UV radiation) Cells were incubated for 72 h and ... implantable hydrogels based on gellan gum were prepared as paclitaxel carriers for HER2-positive breast cancer therapy To achieve different degrees of chemical crosslinking, hydrogels were synthesized
Ngày tải lên: 01/01/2023, 14:04
... (http://creativecommons.org/licenses/by-nc-nd/4.0/) Introduction Inflammatory breast cancer (IBC) is the most deadly form of breast cancer, with a higher incidence among younger women, with a mean ... induce breast cancer stem-like cells in human triple-negative breast cancer (TNBC) and IBC[11] cells Furthermore, correlations were found between the AHR signalling pathway and markers of cancer ... rate for IBC patients who underwent mas-tectomy and a 57% survival rate for IBC patients who underwent a partial mastectomy [4] Relative to the low incidence of IBC (1–6% of all breast cancers)
Ngày tải lên: 14/01/2020, 02:39
Exploratory analysis of immune checkpoint receptor expression by circulating T cells and tumor specimens in patients receiving neo-adjuvant chemotherapy for operable breast cancer
... suitable for NAC Exclusion criteria were the presence of inoperable BC or receipt of chemotherapy for breast cancer prior to study enrollment All patients were required to sign an IRB-approved informed ... checkpoint (ICP) inhibitors and neo-adjuvant chemotherapy (NAC) have begun testing in patients with breast cancer (BC), the effects of chemotherapy on ICP expression in circulating T cells and ... by circulating T cells and tumor specimens in patients receiving neo-adjuvant chemotherapy for operable breast cancer Robert Wesolowski1,2,3*† , Andrew Stiff1,2†, Dionisia Quiroga1,2, Christopher
Ngày tải lên: 30/05/2020, 22:02
Understanding adjuvant endocrine therapy persistence in breast Cancer survivors
... III breast cancer, referred to the British Columbia Cancer Agency (BCCA) between January 2005 and August 2012, without a prior cancer diagnosis, re-currence of breast cancer, or secondary cancer ... experienced by breast cancer survivors hold the potential to increase both women’s quality and quantity of life Keywords: Adjuvant endocrine therapy, Medication persistence, Breast cancer, Cancer survivorship ... of breast cancer recurrence and mortality Notwithstanding the demonstrated efficacy of AET, 31–73% of breast cancer survivors do not persist with AET The purpose of this study was to explore breast
Ngày tải lên: 03/07/2020, 01:10
Patterns of recurrence after selective postoperative radiation therapy for patients with head and neck squamous cell carcinoma
... Concurrent systemic therapy RT total dose (Gy) Radiation technique RT radiation therapy, NAC neoadjuvant chemotherapy, ND neck dissection, EBRT external beam radiation therapy BT brachytherapy, LN lymph ... favorable for patients assigned to postoperative radiation therapy compared with those assigned to preoperative radi-ation therapy (65 % vs 48 %, p = 0.04), and the post-operative radiation therapy ... strategy and radiation field was not uniformed according to several patient’s clinical backgrounds For example, treatment plans were heterogeneous in-cluding bioradiation, chemoradiation, or radiation
Ngày tải lên: 21/09/2020, 09:19
Clinical outcomes and prognostic factors of cyberknife stereotactic body radiation therapy for unresectable hepatocellular carcinoma
... Stereotactic body radiation therapy for primary and metastatic liver tumros: A single intstitution phase I-II study Acta Oncol. 2006;45:831 –7. 22 Hawkins M, Dawson L Radiation therapy for hepatocellular ... Pointreau Y, Calais G Robotic stereotactic radiation therapy for tumors of the liver: radiation-induced liver disease, incidence and predictive factors Cancer Radiother 2014;18(3):191 –7. 35 Takeda ... greater susceptibility to radiation-induced liver disease after three-dimensional conformal radiotherapy Asian patients with HCC usually have viral hepatitis, therefore, dose distribution in
Ngày tải lên: 21/09/2020, 10:11
Study design and methods for the Breast Cancer and Exercise Trial in Alberta (BETA)
... the mechanisms underlying breast cancer etiology The Breast Cancer and Exercise Trial in Alberta (BETA) - a follow-up study to the Alberta Physical Activity and Breast Cancer Prevention (ALPHA) ... is to inform public health guidelines for reducing breast cancer risk through physical activity Trial registration: Clinical Trials Registration Number: NCT01435005 Keywords: Breast cancer, Physical ... reductions in breast cancer risk compared to the current moderate volume recommendations Such information will inform public health guidelines addressing how to lower post-menopausal breast cancer risk
Ngày tải lên: 14/10/2020, 13:24
Stereotactic body radiation therapy for post-pulmonary lobectomy isolated lung metastasis of thoracic tumor: Survival and side effects
... salvage treatments for colorectal cancer, breast cancer and other types of tumors, and rarely for thoracic tumor after pulmonary lobectomy Hypo-fractionated stereotactic body radiation therapy (SBRT) ... Stereotactic body radiation therapy (SBRT) has emerged as an alternative treatment for patients with early stage non-small cell lung cancer (NSCLC) or metastatic pulmonary tumors However, for isolated ... MA, Forquer JA, Hoopes D, Timmerman RD: Stereotactic body radiation therapy for early-stage non-small-cell lung cancer Expert Rev Anticancer Ther 2008, 8:87 –98. 19 Therasse P, Arbuck SG, Eisenhauer
Ngày tải lên: 14/10/2020, 16:13
Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and
... target for IBC 1 Introduction Inflammatory breast cancer (IBC) is the most aggressive and deadly variant of primary breast cancer Although IBC is considered rare in the United States (1–4% of all breast ... July 2021, accepted 2 August 2021) doi:10.1002/1878-0261.13074 Inflammatory breast cancer (IBC) is an aggressive form of primary breast cancer characterized by rapid onset and high risk of metastasis ... brain metastasis; inflammatory breast cancer; LCN2; lipocalin 2; skin invasion Correspondence B G Debeb, Department of Breast Medical Oncology, Section of Translational Breast Cancer Research,
Ngày tải lên: 30/10/2022, 20:44
influence of internal fixation systems on radiation therapy for spinal tumor
... postoperative radiation therapy or chemotherapy Radiation therapy, surgical therapy, and chemotherapy are the three major clinical approaches currently in use for tumor treatment.(8) Radiation therapy ... 45%, which includes 22% by surgical therapy, 18% by radiation therapy, and 5% by chemotherapy.(10,11) Therefore, radiation therapy is one of the major approaches for treatment of tumor Use of an ... influence of internal fixation systems on radiation therapy for spinal tumor was investigated in order to derive a theoretical basis for adjustment of radiation dose for patients with spinal tumor and
Ngày tải lên: 04/12/2022, 14:54
mutational studies on single circulating tumor cells isolated from the blood of inflammatory breast cancer patients
... in cancer and are among the key driving factors in triple-negative breast cancer (TNBC) [20] Furthermore, TP53 mutations are more frequent in inflammatory breast cancer (50%) than in non-inflammatory ... accounts for only 2–6% of all breast cancer cases in the United States and up to 20% of all breast cancer cases globally [4 7] Due to its propensity to rapidly metastasize, it is responsible for a ... Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA DOI 10.1007/s10549-017-4176-x Trang 2Inflammatory breast cancer (IBC) is a very aggressive type of advanced breast cancer with
Ngày tải lên: 04/12/2022, 15:51
Radiation therapy techniques and treatment planning for breast cancer
... delineation for elective radiation therapy of early stage breast cancer Radiother Oncol 114:3–10 21 Moran MS, Haffty BG (2009) Radiation techniques and toxicities for locally advanced breast cancer ... different radiotherapy techniques for breast cancer, and the association to irradiated lung volume and dose Breast Cancer Res Treat 68(3):199–210 8 Blom Goldman U et al (2010) Reduction of radiation ... pneumonitis by V20-constraints in breast cancer Radiat Oncol 5:99 9 Whelan TJ et al (2010) Long-term results of hypofractionated radiation therapy for breast cancer N Engl J Med 362(6):513–520
Ngày tải lên: 14/05/2018, 13:25
Breast Cancer Atlas for radiation therapy
... Trang 1Breast Cancer Atlas for Radiation Therapy Planning: Consensus Definitions Trang 21 Medical College of Wisconsin, 2 Virginia Commonwealth University, 3 M.D Anderson Cancer Center, ... 12Case A- Intact post lumpectomy breast• Stage I ( T1c, N0, M0) Left breast cancer • Radiation: Breast • Six surgical clips placed at lumpectomy site – 4 wire markers for clinical estimate of cranial, ... Trang 8Contouring Comments: Breast and Chestwall 1 Breast: After appropriate lumpectomy for breast only treatment a Cranial border is highly variable depending on breast size and patient position
Ngày tải lên: 18/11/2022, 23:34
Báo cáo sinh học: " Encapsulation of docetaxel in oily core polyester nanocapsule intended for breast cancer therapy" pptx
... acceptance Fully formattedPDF and full text (HTML) versions will be made available soon Encapsulation of docetaxel in oily core polyester nanocapsule intended for breast cancer therapy Nanoscale ... nanocapsule form This observation was consistent with a previous report [48] related to a nanoparticulate form of another anticancer drug (doxorubicin) tested on a different breast cancer cell ... characterized for particle size, zeta potential, EE%, drug release kinetics, morphology, crystallinity, and cytotoxicity on the SUM 225 breast cancer cell line by dynamic light scattering, high performance
Ngày tải lên: 18/06/2014, 22:20
Báo cáo khoa học: "Barriers to adequate follow-up during adjuvant therapy may be important factors in the worse outcome for Black women after breast cancer treatment" doc
... chemotherapy Breast Cancer Res Treat 2003, 81(1):21-31. 56 Li BD, Brown WA, Ampil FL, Burton GV, Yu H, McDonald JC: Patient compliance is critical for equivalent clinical out-comes for breast cancer ... following breast conservation therapy in African-American women with invasive breast cancer Am J Surg 2000, 179(1):22-26. 33. Cunningham JE, Butler WM: Racial disparities in female breast cancer ... Bevers TB: Are there racial differences in breast cancer treatments and clin-ical outcomes for women treated at M.D Anderson Cancer Center? Breast Cancer Res Treat 2006, 102(3):347-356 Epub
Ngày tải lên: 09/08/2014, 07:21
Báo cáo khoa học: "An ultrasonographic evaluation of skin thickness in breast cancer patients after postmastectomy radiation therapy" docx
... Back M, Guerrieri M, Wratten C, Steigler A: Impact of Radiation Therapy on Acute Toxicity in Breast Conservation Therapy for Early Breast Cancer. Clin Oncol 2004, 16:12-16. 37 Mellor RH, Bush ... post-operative breast irradiation Radiother, Oncol 1992, 25:19-24. 7 Paszat LF, Mackillop WJ, Groome PA: Mortality from myocardial infarction following postlumpectomy radiotherapy for breast cancer: ... irradiation However, few clinical data were available in the litera-ture for documenting the ultrasonic properties of fibro-tic skin in vivo for postmastectomy breast cancer patients with radiation
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: " Validity and reliability testing of two instruments to measure breast cancer patients'''' concerns and information needs relating to radiation therapy" pdf
... specific radiation therapy satisfaction questions: "Why receiving radiation therapy; how radiation therapy is car-ried out, the radiation therapy, tailor made for you; preparation before radiation ... examinations would be per-formed • Why receiving radiation therapy • How radiation therapy is carried out • The radiation therapy, tailor made for you • Preparation before radiation therapy • Implications ... interviews with 34 breast cancer patients and 14 health professionals to further determine the information needs that breast cancer patients had before, during and after their radiation therapy treatment
Ngày tải lên: 09/08/2014, 10:21
báo cáo khoa học: "Free Rhodium (II) citrate and rhodium (II) citrate magnetic carriers as potential strategies for breast cancer therapy" docx
... Rhodium (II) citrate and rhodium (II) citrate magnetic carriers as potential strategies for breast cancer therapy Marcella LB Carneiro1*†, Eloiza S Nunes2, Raphael CA Peixoto1, Ricardo GS Oliveira1, ... promising agent for chemotherapy Nevertheless, few studies have been performed to explore this potential Superparamagnetic particles of iron oxide (SPIOs) represent an attractive platform as carriers ... on breast carcinoma cells than on breast normal cells, which is the opposite of the results observed with free Rh2(H2cit)4treatment Thus, magnetic nanoparticles represent an attractive platform
Ngày tải lên: 11/08/2014, 00:23
Use of IPs cell derived neural stem cells as a cellular vehicle for glioma and breast cancer therapy
... targeted treatments available Triple-negative breast cancer (TNBC) accounts for 15% to 20% of breast cancers (Konecny G Trang 15et al., 2003) Therapy for TNBC is empiric and not based on tumor biology, ... experiments 83 Trang 12Figure 14 HSVtk/GCV and CD/5-FC for breast cancer therapy mediated by iPSC-NSC 86 Figure 15 Survival analysis of breast cancer receiving HSVtk/GCV or CD/5-FC treatment mediated ... approximately one in five breast cancers is human epidermal growth factor receptor 2/erb-B2 (HER2)-positive breast cancers Hormone receptor-positive and HER2-positive breast cancers have highly effective
Ngày tải lên: 09/09/2015, 18:56
A dosimetric skin study on postmastectomy breast cancer patients undergoing radiation therapy
... role of radiation therapy in improving the local control of breast cancer 2.2 ROLE OF RADIATION THERAPY Radiotherapy plays an integral role in the management of patients with breast cancer whether ... chapter, a background about breast cancer and the role of radiation therapy in the treatment of postmastectomy breast cancer patients is provided Complications of radiotherapy therapy are also discussed ... POSTMASTECTOMY BREAST CANCER PATIENTS UNDERGOING RADIATION THERAPY SHARON WONG MEI MEI THE NATIONAL UNIVERSITY OF SINGAPORE 2011 Trang 2BREAST CANCER PATIENTS UNDERGOING RADIATION THERAPY SHARON
Ngày tải lên: 10/09/2015, 15:53