modeling obesity and its associated disorders in drosophila

... Allergen inhalation induced increases in the TH2 cytokines IL-5 and IL-13 in both strains of mice following allergen chal-lenge (Figure 2B) In Balb/c mice, there was a decrease in the TH1 cytokine ... formalin fixed Lungs were embedded in paraffin, sectioned, and stained with haematoxylin and eosin (H&E) and Periodic Acid Schiff (PAS) To quantify mucin production, we counted airways and ... levels, increased responsiveness to acetylcholine challenge, increased cellu-lar infiltration into the airways and increased mucin pro-duction in Balb/c mice The same inhalation protocol resulted in

Ngày tải lên: 12/08/2014, 15:21

... migration and axon pathfinding are guided by extracellular cues,which initially include netrins, semaphorins, ephrinsand Slits Netrins are secreted proteins that direct axon extension and cellmigration ... extracellular semaphorin (sema) domaindefines Semaphorins Semaphorins are expressed in a wide variety of neuronaland nonneuronal tissues (reviewed in (Kolodkin and Ginty, 1997) Ephrinreceptors (Eph) ... streaming in oocytes……… 125 Fig 5.8: Bifocal and Homer localisation in the presence and absence of intact microfilaments……… 128 Fig 5.9: Osk protein and RNA localisation in WT and hom oocytes in

Ngày tải lên: 12/09/2015, 09:42

... 4.Hindanda‟amuu5.Dhiyotti hinargamu 2019 Deebiinulfaatayknhindanda‟amuuyoota‟ees 1.Dhaabbileen fayyaa hinjiran ababnimaalif ? 2.Dhaabbileenfayyadhiyootihinjiran 3.Tajaajillakafaaluu waan hin dandeenyeef ... nursing and midwifery for the sharing their comments and working together before deadlines My thanks also goes to all my friends and families who provided me with their continuous support and ... DEPARTMENT OF NURSING AND MIDWIFERY MALE PARTNER’S INVOLVEMENT AND ITS ASSOCIATED FACTORS IN PROMOTING SKILLED DELIVERY ATTENDANCE AMONG FATHERS WHO HAVE CHILDREN LESS THAN ONEYEAR OF AGE IN AMBO TOWN,

Ngày tải lên: 15/08/2017, 15:11

... the IA and HI domains in grade 8, but not those in grade 5 In the OD domain, High tra-jectories in grades 3, 5, and 8 were steadily flat, quadratic decreasing, and linear decreasing, respectively ... decreasing, low decreasing in IA, and high worsening, high decreasing, low in ODD) [17] Several risk factors have been reported to associ-ate with high trajectories of HI and IA subtypes, includ-ing ... of 14 DSM-IV-based items, 14% were included in the high increasing trajectory of IA domain and 9% were included in the high decreasing trajectory of HI domain [16] Furthermore, the pattern of

Ngày tải lên: 14/01/2020, 19:05

... dysmenorrhea and daily caffeine intake [34, 40–42] Caffeine, which is the main ingredient of coffee, is an adenosine analogue that in-hibits adenosine (a potent vasodilator) receptors [43] Blocking these ... pain) In multivari-able analysis, only age of menarche, regularity and flow of the menstrual period and weekly drinking of coffee were significantly associated with dysmenor-rhea These findings ... drinking of tea Weekly drinking of green tea Weekly drinking of carbonated drinks BMI e Physical activity in the previous week f a Crude unadjusted odds ratio; b P-values were generated using

Ngày tải lên: 01/02/2020, 05:57

... single estimation Factors associated with neonatal hypothermia in eastern Africa Delayed initiation of breastfeeding Timely initiation of breastfeeding is considered as initiat-ing breastfeedinitiat-ing ... country, setting, study design, the definition of hypothermia, adjusted co-founders, the odd ratio of factors, and main findings The data extraction sheet was piloted using 4 papers randomly, and it ... hypothermia in Eastern Africa remains high Delay in initiation of breastfeeding, having a neonatal health problem, being low birth weight, preterm, and nighttime delivery were identified associated

Ngày tải lên: 29/05/2020, 19:05

... online databases including MEDLINE/PubMed, Scopus, Web of Science, Maternity and Infant Care and Wiley Online Library Additionally, bibliographies of identified articles and grey literature, including ... including Google scholar, MEDNAR, and World Wide Science were searched Moreover, missing data were handled by contacting corresponding authors Search terms were formulating using PICO guidelines ... “Repeated Vomiting” AND “Mother’s” OR “Women” AND “Associated factors” AND Ethiopia and related terms Systematic review with narrative synthesis was used to summarize the findings of articles in Ethiopia

Ngày tải lên: 29/05/2020, 19:21

... outcomes and associated factors in Ethiopia using the standard PRISMA checklist guideline Fig 1 Flow chart of study selection for systematic review and meta-analysis of adverse fetal outcomes and its ... (7.21–12.91) This study finding is in line with the study done in Indonesia [12.9%], Armenia [9.0%, higher than the study conducted in Nigeria [6.3%] and lower than the study done in Kenya [12.3%], ... problems [27] The odds of living in rural were two times more likely to develop adverse fetal outcomes This study finding is in line with the study done in China [61], and Brazil [62] This might

Ngày tải lên: 29/07/2020, 23:08

... [15,21] Indirect fluorescent antibody testing and conventional RT-PCR including its variants (such as nested RT-PCR and RT-PCR-coupled denaturing gradient gel electrophoresis) are available only in ... upon adding maintenance medium post-inoculation), 7 and 14 post-inoculation, observed for CPE and frozen at −80oC At the end of all incubations, the contents from infected as well as uninfected ... between the in vivo ISAV virulence and its CHSE-phenotypes exists remains to be investigated The exact reason why some ISAV isolates cause CPE and others do not in the CHSE-214 cell line remains unknown

Ngày tải lên: 07/08/2014, 18:21

... 65) participated using simple random sampling method In district 2, 40 classes in 10 schools participated (50% of eligible classes, n = 80) using simple random sampling method In district 1, classes ... symptoms and its associated related factors among female adolescents in Iran The findings of the present study indicated high prevalence rate of depression (72.6%) in female adolescent in the city ... medicine and engineering, and a lack of helpful counselors and supporters in schools [16] Another possible cause might be that norms and values of sexual relationships also have been acted in Iran

Ngày tải lên: 10/01/2020, 12:13

... childhood and adolescence obesity, incidence studies must be carried out The main objective of this study was to determine childhood obesity incidence and its potential predictors in Tehranian ... of obesity among 5–19 years old children and adolescents was published The study showed an increasing trend of obesity worldwide; prevalence of obesity in 1975 was 0.7% in girls and 0.9% in boys, ... data regarding incidence of obesity in childhood Few studies have investi-gated this subject in developed countries Cunningham et al [10] reported a cumulative obesity incidence of 11.9% in the U.S

Ngày tải lên: 01/02/2020, 03:50

... result was in line with studies conducted in India [57], and Sri Lanka [58]; and with systematic reviews conducted in Low and Middle income countries [59], and Africa, China and Latin America ... cooking foods in living rooms will cause indoor air pollution and holding a child on back while cooking foods can increase the probability of inhaling smokes and food vapors (steams) which in ... source, cooking food in living room, caring of a child on mother during cooking, being unvaccinated, on-exclusive breast feeding,child history of ARTI, and parental smoking were independent potential

Ngày tải lên: 29/05/2020, 19:20

... to induce high mutation frequency of cellular genes (immunoglobulin heavy chain, Bcl-6, p53 and beta-catenin genes), in B-cell lines and PBMCs in vitro, by inducing double strand breaks and ... reading frame (ORF) encoding a polyprotein The structural proteins are encoded in the N-terminal part of the ORF, and the nonstructural proteins are encoded in the remaining part of the (Miller and ... potentially involved in HCV associated lymphomagenesis, derives from the high-affinity binding between HCV-E2 and one of its receptors, the tetraspanin CD81, expressed on B-cellslymphocyte (Marcucci and

Ngày tải lên: 04/11/2020, 22:37

... activity in cultured murine keratinocytes,^" and in human keratinocytes,^''''^ mainly by inhibiting DNA synthesis At concentrations in excess of 40 mM, cytotoxic effects were evident in both murine ... ([^H]uri-dine incorporation) in murine keratinocytes or protein synthesis ([^^S]methionine incorporation) in cultures of human melanoma cells.^^ Effects on Cutaneous Microflora In vitro tests, using ... transport in normal cells accounts for its ineffec-tiveness in these cells Azelaic acid acts as an antikeratinizing agent and influences the differentiation of human keratinocytes in vivo It

Ngày tải lên: 24/10/2022, 19:18

... most in need may be those obese and feeling depressed. Regard- ing mental HRQL, obesity and diabetes as interacting factors seem worth of further scrutiny. In future studies, the underlying p ... with obesity, abdominal obesity, depressed mood, and diabetes. In contrast, mental HRQL is significantly lower only in participants with depressed mood, and marginally decreased in those not living ... for gen eral and abdominal obesity in a community sample of po stmenopausal women. Both obesity-indicators were associated with diabetes but not depressed m ood, the latter being in line with cross-sec-

Ngày tải lên: 20/06/2014, 15:20

... protein kinase (MAPK) proteins was examined using SuperAr-ray CASE™ cell-based ELISA kit [18], and specific MAPK inhibitors (p38 inhibitor SB202190, Erk inhibitor PD98059, and Jun N-terminal Kinase ... that a linear 18-residue peptide PIP-18 potently inhibits IL-1β-induced secre-tions of sPLA2 and matrix metalloproteinases (MMPs; 1, 2, 3, and 9) in RA synovial fibroblasts (SF), at protein and mRNA ... may be incomplete inactiva-tion of sPLA2 in the SF due to inadequate dose of the inhibitor used in the trial [32] As sPLA2 and MMP inhibitors have lim-ited efficacy in RA, the use of an inhibitor

Ngày tải lên: 09/08/2014, 14:22

... divergence at the Adh locus and for ethanol and acetic-acid tolerance in Indian populations of Drosophila melanogaster could be explained by balancing natural selection varying spatially along the ... electrophoresis at 250 V and 25 mA at 4°C for 4 h and gel slices were stained for ADH (Harris and Hopkinson, 1976) The genetic control of ADH banding Trang 3patterns interpreted from the segregation ... latitudinal clines across different continental populations provides strong evidence of natural selection maintaining such clinal allozymic variation (David, 1982; Oakeshott et al 1982; Anderson

Ngày tải lên: 09/08/2014, 18:21

... a continuous sinusoidal staining and in the stroma of portal tracts (Fig. 7A). In the cirrhotic liver, the sinusoidal staining was enhanced, whereas a very faint staining was observed in fibrous ... remains hypothetical. In the case of s-LIF-D, initiation at the AUG within exon D would result in a reading-frame shift following the 6 th amino-acid (aa) and a termination at aa 88, the resulting ... sampling and processing A portion of fresh tissue samples was routinely formalin- fixed and paraffin-embedded for diagnosis and a portion immediately frozen in liquid nitrogen-cooled isopentane and

Ngày tải lên: 13/08/2014, 13:20

... Katz Broadband demand and economic impact in Latin America Proceedings of the 3 rd ACORN-REDECOM Conference Mexico City May 22-23 rd 2009 1 ESTIMATING BROADBAND DEMAND AND ITS ECONOMIC ... broadband density in 2008 reached 5.5 %, while in industrialized countries it exceeded 25%. In the emerging world, China has reached 5.1%, and Malaysia 4.6 %. Among emerging economies, Latin America ... outsourcing effect. While a better understanding of these combined "network effects" is being gained, the research is still at its initial stages of quantifying the combined impact.

Ngày tải lên: 21/08/2014, 15:25

... our findings on manufacturing are in line with the cross-country findings on FDI and trade reported in Aizenman and Noy (2005). Using Granger causality tests on disaggregated measures of financial ... meeting certain conditions; opening up to FDI in various sectors, including mining, financial services and telecommunication (though still subject to limits of foreign ownership); lifting foreign ... variables in the primary sector. Most interestingly, and contrary to the widespread view that booming FDI in the services sector is driving growth in India, feedback effects between FDI and output...

Ngày tải lên: 21/02/2014, 01:20