localization of ebers and their interaction with cellular proteins

... 10.1186/s12885-017-3284-7 RESEARCH ARTICLE Open Access Effect of genetic variants and traits related to glucose metabolism and their interaction with obesity on breast and colorectal cancer risk among postmenopausal ... overexpression of these receptors and multiple abnormal cellular signaling cascades, and therefore may be associated with carcinogenesis Considering the relationships of these glycemic phenotypes and cancer ... associated with breast cancer and CRC risk, and these SNP–cancer associations differed between non-obese and obese women In both strata, the direct effect of cancer risk associated with the SNP

Ngày tải lên: 06/08/2020, 07:48

... e-health users and their interaction with e-health systems Ole Norgaard Department of Public Health University of Copenhagen, Denmark E-mail: ole@norgaard.dk Dorthe Furstrand Department of Public ... literacy The aim of this study was to develop a new conceptualisation of e-health literacy with consideration of the experiences of a wide range of stakeholders and in alignment with current technologies ... framework for characterizing e-health users and their interaction with ehealth systems Ole Norgaard University of Copenhagen, Denmark Dorthe Furstrand University of Copenhagen, Denmark Danish Cancer

Ngày tải lên: 15/01/2020, 00:06

... mixture of phospholipoproteins and lipids, reduces surface tension at the AWI of alveoli, and its deficiency can lead to alveolar collapse and respiratory failure.Plasma proteins and their interactions ... liquid-expanded (LE), liquid-condensed (LC), and the coexistence of liquid-condensed and liquid-expanded (LE–LC), along with the collapse of the interfacial film Additionally, the isotherm of β-casein ... proteins and their interactions with polymers at the AWI, enhancing both methodological approaches and the understanding of interfacial behavior Chapter 2 focuses on the morphological study of human

Ngày tải lên: 24/07/2023, 06:47

... Fecundity, viability and rate of development Thirty pairs each of S and wild-type flies, offspring of S females, were isolated in tubes of nutrient medium and transferred daily for a period of 3 days For ... and those of ten other pairs at 24 &dquo;C For each tube, twenty F individuals of each sex were examined and the frequency of both S and wild-type calculated Infectivity of the extracts of ... small number of categories of the first variable and to the number of individuals recorded C Effect of the temperature on the expression of S phenotype Table 5 presents the frequency of S and normal

Ngày tải lên: 09/08/2014, 22:22

... frequency, and probability value for each site is shown in Table 4 Of interest, the SNP sites (s60 and s222) from the promoter and s1448 from the exon of BnA7.SUT1 were associated with EFB and TSW and ... associated with yield-related traits, and allelic variation at the promoter and CDS of BnA7.SUT1 correlated with expression pattern and phenotype Polymorphisms at the promoter and CDS regions with ... demonstrated that SUT co-localizes with yield-related quantitative trait loci This paper reports the isolation of BnA7.SUT1 alleles and their promoters and their association with yield-related traits

Ngày tải lên: 11/08/2014, 11:21

... all lines) In agreement with the lack of effect of DS10:DR2 on thermotolerance, we observed similar accumulation levels of CI and CII sHSPs and of HSP101 in the seeds of DS10:DR2 lines compared ... consistent with the multiple integration of DS10:DR2 This contrasted with the mentioned lack of effects of single overexpression of HaDREB2 in the DS10:DR2 seeds Therefore, both the positive and nega-tive ... performed with two pairs of A9/ DR2 lines (A9#14-5/DR2#5-7 and A9#14-5/DR2#23-5) compared to their respective sibling lines without DR2 (A9#14-5/#5-4 and A9#14-5/#23-6) Also shown are pictures of representative

Ngày tải lên: 12/08/2014, 03:20

... A and B: projections of section stacks of the stigma surface at stages 1 and 3, respectively The fluorescence localizes in association with the stigmatic papillae C and D: optical section -and ... applica-tion of the scavenger sodium pyruvate, the strong reac-tion of the stigmas to TMB (with a practically identical distribution of the labelling by TMB and DCFH2-DA), and the relative low presence of ... projection of the surface of the central area of the stigma at stage 4 Note the differences in both the texture of the exudate, and the intensity of the labelling D: optical section of several

Ngày tải lên: 12/08/2014, 03:21

... find ways of facilitating the maintenance of physical function, health and independence and quality of life of older individuals. This in turn will help reduce the substantial financial and personal ... assessment of patterns and levels of activity, functionality, well being and perceptions of the environment. - 5 - We have previously reported the associations between trips per week and of accelerometer ... as the proportion of trips. .. physical activity and with participant characteristics help improve our understanding of the importance of “getting out and about behaviour

Ngày tải lên: 14/08/2014, 08:21

... strategy list, and further “wrote in” their own strategies The results show that all students favor some strategies, regardless of their listening proficiency The difference between high- and low-level ... TABLE OF CONTENTS Declaration Acknowledgements Abstract Table of contents List of charts and tables Part one: Introduction……… 1 Rationale……… 2 The aims of the study……… 3 Scope of the ... 3……… Trang 4Appendix 4……… LIST OF ABBRIVIATIONS LP: language proficiency HLP: High language proficiency MLP: Medium language proficiency LLP: Low language proficiency * Strategy likely stimulated

Ngày tải lên: 10/08/2015, 19:48

... qualitative studies of the structures and functions of the EEN and its three domains. Native PAGE, Circular Dichroism and NMR were used to exploit the interaction of Ca2+ with EEN and its domains. 2-D NMR and ... the contribution of these results on understanding of the possible role of the 3 random coil PRD and the influence of Ca2+ on EEN in vitro. Chapter 6 concludes the finding of this research and gives ... Characterization of the Interaction of EEN and Its Domains with Ca2+ and Proline Rich Domain ZHANG YUNING A THESIS SUBMITTED TO THE DEPARTMENT OF BIOLOGICAL SCIENCE NATIONAL UNIVERSITY OF SINGAPORE FOR

Ngày tải lên: 03/10/2015, 20:32

... Trang 2overview of these amorphogenesis inducing agent and their interactions with cellulose Name: Nguyen Thi Minh Thu 2016.11.18 Trang 31 Overview2 The amorphogenesis – inducing proteins CONTENTS ... loosening proteins involved in cell enlargement and in a variety of other developmental processes in which cell – wall modification occurs  The structure of expansin includes two domains (domain 1 and ... structure of GH45 It lacks of a second asparate so do not be hydrolytic activity • Domain 2 was initially speculated tobe a CBM on the basic of conserved aromatic and polar residues on the surface of

Ngày tải lên: 21/11/2016, 11:34

... Trang 1Dynamics of cyanobacteria and cyanobacterial toxins andtheir correlation with environmental parameters in Tri An Reservoir, Vietnam Thanh-Son Dao, Jorge Nimptsch and Claudia Wiegand ABSTRACT ... a surface area of 323 km2, is around 50 km long, 2–15 km wide, with mean and maximum depths of 8.4 m and 27 m, respectively (Figure 1) It has a total volume of 2.7 billion m3 and an elevation ... 2009, with the exception of January 2009 (Figure 1) Physical and chemical factors were also measured at the same six sites and times, except in April 2008 Qualitative samples of algae and cyanobacteria

Ngày tải lên: 17/12/2017, 17:37

... 1SHELLS HAVING THE FORM OF A SURFACE OF REVOLUTION AND LOADED SYMMETRICALLY WITH RESPECT TO THEIR AXIS 127 Equations of Equilibrium Let us consider the conditions of equilibrium of an element cut ... (e) and assume Having this expression for Q, and using the relations (b), (c), and (d) of Art 128 and the relations (p), (q), and (r) of Art 129, all the quantities defining the bending of the ... conditions on both the lower and the upper edges of the shell This requires consideration of both the integrals (j) and (k) of Eq (d) (see p 541) and finally results in a solution of Eq (320) which con-

Ngày tải lên: 30/04/2018, 19:26

... stoichiometry of the complex between RI and RATEs, 100 or 200 pmol of RI was incubated either with 100 pmol of SGRSGRSG-RATE or with 100 pmol of RNase A at 25 °C for 15 in 15 lL of 0.1 m sodium ... catalytically active and that the activity decrease [16] is a result of the tandemization Accessibility of the linker of SGRSGRSG-RATE in the presence of RI The accessibility of the linker sequence ... the other hand, the decreased activity of the RATEs as compared with RNase A ([16] and Table 1) indicate a negative influence of the tandemization on the catalytic efficiency The recovery of activity...

Ngày tải lên: 22/03/2014, 16:21

... because of their unique properties that differ from their linear analogues However, examples of these molecules are rare, mainly attributed to the difficulty in their preparation and lack of the ... aromatic oligoamides with biomacromolecules, such as oligonucleotides and proteins The aim of this thesis was to investigate the structural and physical properties of a 13 new class of backbone-rigidified ... specificity and affinity Figure 1.6 Solid state structure of L-tartaric Acid-binding M-1 helix (a) CPK and (b) stick representations of the M-1 helix (c) Top view of the central part of the M-1...

Ngày tải lên: 10/09/2015, 15:49

... angle of 63º between axis ac and plane of the molecules, all the other three dimers (2a, 2c and 2d) are stacked along axis a with angles of 90º, 53º and 70º, respectively, between axis a and plane ... study and elucidation of the higher ordered structures of these folding molecules with interesting properties and applications Many aspects of the synthetic chemistry associated with this class of ... from 3a and generated by breaking H-bond of Oa···Hb (1A & 1B), Hb···Oc (2A & 2B), Oc···Hd (3A & 3B) and Hd···Oe (4A & 4B), and by breaking H-bonds of both Oa···Hb and Hb···Oc (5A & 5B), and both...

Ngày tải lên: 10/09/2015, 15:49

... previously.3c Figure 3.1 Side and top views of oligoamides and 6: (a) crystal structure of pentamer 5a, (b) ab initio calculated structure of 5a and (c) crystal structure of hexamer 6a Interior methoxy ... by slow evaporation of 5a and 6a in mixed solvents containing hexane and chloroform 91 (1:1 v/v) for 5a and hexane and dichloromethane (1:1 v/v) for 6a at room temperature Their crystal structures ... protons and their adjacent interior methoxy protons, (f) Chemical structure of 6b More NOESY, ROESY and TOXSY studies of 6b were demonstrated in Figure 3.8 and Figure 3.9 Figure 3.8c and 3.8d...

Ngày tải lên: 10/09/2015, 15:49

... indicator of the presence of strong H-bonding interactions, leading to the rigidification of the amide linkages and a crescent aromatic backbone Figure 4.2 1H NMR spectrum (500 MHz, 298 K, CDCl3) of ... structure of pentamer (a) top view with interior methoxy methyl groups omitted for clarity of view, (b) top view and (c) side view both with methoxy methyl groups in CPK representations 4.2.5 Design of ... ppm as a result of the H-bonding ability of DMSO 4.2.7 Crystal Structure of a Tetramer and Computational Molecular Modeling of Circular Pentamer To demonstrate the existence of intramolecular...

Ngày tải lên: 10/09/2015, 15:49

... analysis of inhibitory effect of 10a in 50 mM NaCl, (d) PAGE analysis of inhibitory effect of 11a in 50 mM KCl and (e) PAGE analysis of inhibitory effect of 11a in 50 mM NaCl (f) Comparison of inhibitory ... other hand, the quantity of PCR product of 11a in Na+ solution also decreased sharply compared to 10a, indicating the decrease of the ligands’ binding selectivity in company with the increase of ... 5.14 Influence of 10a and 11a on PCR product by using ODN-3 as the PCR template: (a) CD spectra of ODN-1 in the presence of 100 mM KCl and NaCl, (b) PAGE analysis of inhibitory effect of 10a in 50...

Ngày tải lên: 10/09/2015, 15:49

... presence of many proteins was tested As expected, a mixture solution of 10-fold excess of human γ-thrombin, BSA and Factor Xa did not interfere with the detection of trace levels (10 nM) of human ... both Au-T6 and thrombin Our earlier observation and discussion in the duplex approach shows that the interaction of TBA with its complementary DNA strand is stronger than that between TBA and thrombin ... spectra of gold nanoparticles before and after modification with DNA Two Thrombin aptamers TBA (15-mer) and TBA2 (29-mer) and their analogues were chemically coupled to AuNPs via the formation of...

Ngày tải lên: 10/09/2015, 15:49