... intracellular signaling transduction ,altered calcium signaling and a elevated protein kinase A activity ( Langan & McDonald 2009 ) The calcium channels antagonists (verapamil and others) raise ... increases the verapamil maintenance therapy in mania (Giannini et al 2000) This fact favors the idea that an increase in magnesium concentration is an important fact, maybe essential for the therapeutic ... with an significant augmentation of plasma zinc level and decrease of plasma copper concentration We consider that there changes is in important part of the mechanism of pharmacotherapeutic action
Ngày tải lên: 08/03/2014, 00:20
... games for a period, and these broadcast royalties are then shared among the teams Trang 12“Is a licensor's advance a financial and monetary liability?”Trang 13Accounting for royalties receivable ... offset against the advance and only once the book generates more royalties than the value of the advance are additional amounts paid to the author These advances are generally not refundable provided ... (IPR) Advance payment may be received from licensee Is the obligation a financial / monetary liability? Advance payment may be made to licensor Is the asset a financial/monetary asset? Is the value
Ngày tải lên: 29/03/2014, 20:20
PERIPHERAL NEUROPATHY - A NEW INSIGHT INTO THE MECHANISM, EVALUATION AND MANAGEMENT OF A COMPLEX DISORDER doc
... Therapeutical Strategies 77 Sabatino Maione, Enza Palazzo, Francesca Guida, Livio Luongo, Dario Siniscalco, Ida Marabese, Francesco Rossi and Vito de Novellis Section Evaluation and Management of ... to AEs [32] 3.1.2 Gabapentin Gabapentin is a synthetic analogue of the neurotransmitter GABA with anticonvulsant activity Although the exact mechanisms of action are unknown, gabapentin appears ... pharmacological management of diabetic neuropathy This was based on trans‐ lational research from animal models of diabetic peripheral neuropathy In the third chapter of section one, Dr Sabatino
Ngày tải lên: 30/03/2014, 23:20
báo cáo hóa học: "Design of a complex virtual reality simulation to train finger motion for persons with hemiparesis: a proof of concept study" docx
... employs a simulated piano that presents visual, auditory and tactile feedback comparable to an actual piano Arm tracking allows patients to train both the arm and hand as a coordinated unit, emphasizing ... combines training of the hand and arm into an integrated task-based simulation This unique training modality is practical and accommodates and safely challenges sub-jects with a range of hand impairments ... presents a full keyboard with a complete range of single notes A list of wav files, each having the sound of a single note of the piano, are pre-loaded into a sound file array The keyboard array of
Ngày tải lên: 19/06/2014, 08:20
Báo cáo toán học: "Stability of the index of a complex of Banach spaces " pot
... the stability theorems can be reduced to the classical ones As a matter of fact, the index of a Fredholm complex of Hilbert spaces is always equal to the index of a certain operator, as our ... Trang 1STABILITY OF THE INDEX OF A COMPLEX OF BANACH SPACES F.-H VASILESCU 1 PRELIMINARIES Let X and Y be two Banach spaces over the complex field C We denote by €(X, Y) the set of all linear and ... However, it seems that the case of commuting operators acting in Banach spaces (and, in general, the case of complexes of Banach spaces) cannot be reduced to the case of one opera- tor, while our
Ngày tải lên: 05/08/2014, 09:46
Báo cáo y học: " The role of recombination in the emergence of a complex and dynamic HIV epidemic" pptx
... fragments in the HIV database can cover a full HIV-1 genome of each subtype, meaning that there was a potential to form any BF recombinants in Argentina and that there was no need to assume that ... Thailand and Myanmar (Additional file 1 Fig S2A); this occurred possibly through drug trafficking routes [26,28] Other Asian countries, for instance, Korea, Japan, and Thailand, appeared to have ... that have been found in Brazil [40] The origin of BF recombinants in South America is not clear, but it appears that at least one of the main introductory routes of HIV-1 into South America was
Ngày tải lên: 12/08/2014, 23:23
potential of a modern vector supercomputer for practical applications performance evaluation of sx ace
... This paper is an extended version of a following poster papers of SC14 and SC15 R Egawa, S Momose, K Komatsu, Y Isobe, H Takizawa, A Musa and H Kobayashi,: “Early Evaluation of the SX-ACE Processor,” ... 256 GB/s ADB is asoftware controllable private cache with 4 ways and 16 banks While the features ofADB are similar to those of conventional caches, ADB can selectively store reusabledata or explicitly ... Section3evaluates thenew features of SX-ACE using several standard benchmark programs Section4dis-cusses the sustained performances and scalabilities of seven practical applications andthe HPCG benchmark
Ngày tải lên: 04/12/2022, 16:06
Ecological performance of a generalized irreversible Carnot heat engine with complex heat transfer law
... heat-transfer surface area of the high- temperature-side heat exchanger , β is the overall heat transfer coefficient and F2 is the heat-transfer surface area of the low-temperature-side heat exchanger Defining ... transfer surface area (F) of the two heat exchangers is assumed to be a constant: F=F1+F2 (3) There exists a constant rate of bypass heat leakage (q) from the heat source to the heat sink Thus ... the optimal ecological performance of the Carnot heat engine with heat resistance and heat leakage (m≠0,n≠0,q> Φ =0, 1), and optimal ecological performance of the irreversible Carnot heat engine
Ngày tải lên: 05/09/2013, 15:28
Báo cáo Y học: Purification and catalytic properties of a CO-oxidizing:H2-evolving enzyme complex from Carboxydothermus hydrogenoformans doc
... (2002) Genetic analysis of the archaeon Methanosarcina barkeri Fusaro reveals a central role for Ech hydrogenase and ferredoxin in methanogenesis and carbon fixation. Proc. Natl Acad.Sci.USA99, 5632–5637. 25. ... molecular mass of 120 kDa. An SDS/PAGE analysis of this fraction showed one protein band with an apparent molecular mass of 62 kDa in samples boiled prior to SDS/PAGE (Fig. 1B). This polypeptide was ... 5717 compared to the hydrogenase subunits. A densitometric analysis revealed a molar ratio of CooS to CooH, the catalytic subunit of the hydrogenase, of 2.1 ± 0.1 : 1 and a molar ratio of CooF to
Ngày tải lên: 23/03/2014, 21:20
Báo cáo Y học: Secretion of a peripheral membrane protein, MFG-E8, as a complex with membrane vesicles A possible role in membrane secretion pptx
... c ontaining an XbaI site a s follows: 5¢-ATGCAGGTCTCCCGTGTGC-3¢,5¢-AT TCTAGAG GCTAGGTTGTTGGAAAG-3¢,5¢-AT TCTAGAGGAT GTCTTGAGCCCCTG-3¢ and 5¢-TTCTCGAGCAGGA CTGAGCATTAACAG-3¢. The two DNA fragments ... Biophys. Acta 1199, 87–95. 26. Martinez-Lorenzo, M.J., Anel, A., Gamen, S., Monle, N.I., Lasierra, P., Larrad, L., Pineiro, A., Alava, M.A. & Naval, J. (1999) Activated human T cells release bioactive ... plasmid w ith primers containing an EcoRI site at the 5¢ end as same above and an EcoRV site at the 3¢ end (5¢-CAGATATCTTAGTGCAACTCAC AGCC-3¢). The two PCR products were cloned into a mammalian
Ngày tải lên: 24/03/2014, 03:21
Báo cáo khoa học: Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern pot
... GC-A receptor consists of an extracellular ligand-binding domain of approximately 441 amino acids (aa), a short membrane-spanning region (21 aa) and an intracellular portion (567 aa), containing ... Trang 1receptor for atrial natriuretic peptide, is associated witha complex phosphorylation pattern Juliane Schro¨ter1, Rene´ P Zahedi2, Michael Hartmann1, Birgit Gaßner1, Alexandra Gazinski1, ... phosphorylation at Ser487 MS quantification based on multiple reaction monitoring was then applied to Trang 3analyse the phosphorylation pattern of GC-A inHEK293 cells under basal conditions and after ANP-provoked
Ngày tải lên: 29/03/2014, 09:20
Báo cáo khoa học: Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage potx
... that cH2AX is removed from the site of DNA damage before it is dephosphorylated If this is the case, removal from the action of the ataxia telangiectasia mutated (ATM)⁄ ataxia telangiectasia and ... telangiectasia and RAD53 related (ATR) kinases at the site of DNA damage may decrease the kinase⁄ phosphatase ratio and allow the phosphatase to dephosphorylate cH2AX In mammalian cells, PP2A isoforms, the ... Abbreviations ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia and RAD53 related; 4NQO, 4-nitroquinoline 1-oxide; FACS, fluorescent activated cell sorter; H2AX, histone 2AX; MMS,
Ngày tải lên: 30/03/2014, 04:20
Báo cáo khoa học: The HS:1 serostrain of Campylobacter jejuni has a complex teichoic acid-like capsular polysaccharide with nonstoichiometric fructofuranose branches and O-methyl phosphoramidate groups pot
... locus and a limited number of sugars The Gram-negative, spiral-shaped bacterium Campylobacter jejuni is one of the leading causative agents of human enteritis and surpasses Salmonella, Shigella and ... GB (1999) Isolation and chemical characterization of a capsular polysaccharide antigen shared by clinical isolates of Enterococcus faecalis and vancomycin-resistant Enterococcus faecium Infect ... H4 labeled A2a, A2b, A3a, A3b, A4a and A4b, respectively (Fig 4A) The 1D-NOESY of Gal H-4a showed NOEs for Gal H-2a, Gal H-3a, Gal H-5 and Gal H-6 ⁄ 6¢, as well as for Fru H-4 and Fru H-6 ⁄ 6¢
Ngày tải lên: 30/03/2014, 20:20
Báo cáo khoa học: Biotinylation in the hyperthermophile Aquifex aeolicus Isolation of a cross-linked BPL:BCCP complex pptx
... and mutagenic changes are shown in bold) BPL-for, 5¢-TTCTTAACCATGG GCTTCAAAAACCTGAT-CTGG-3¢; BPL-rev, 5¢-TTAA GGATCCTAAGAACGAGACAGGCTGAACTCTCC-3¢; BCCPD67, 5¢-GTAACCATGGGTGAACAGGAAGA A-3¢; BCCP-rev, ... BCCP-rev, 5¢-GGATCCTTAAACGTTTGTGTC TATAAG-3¢; BCCP K117L, 5¢-GAAGCTCTACTG GTTATGAAC-3¢ DNA was isolated from agarose using a QIAquick Gel Extraction Kit, and plasmid DNA was purified using a QIAprep ... combined and the molecular mass determined by theMAXENT AND TRANSFORMalgorithms of theMASS LYNX software (MicroMass) Assay ofA aeolicus BPL BPL activity was assayed by measuring the incorporation of
Ngày tải lên: 31/03/2014, 07:20
Báo cáo hóa học: " Research Article Equivalent Solutions of Nonlinear Equations in a Topological Vector Space with a Wedge" doc
... Journal of Inequalities and Applications the solvability of abstract second-kind equations of type (1.1) in a Banach space with a normal cone, we refer, for example, to [2] Definitions, notation, and ... operators leaving invariant a cone in a Banach space,” ı American Mathematical Society Translations, vol 1950, no 26, p 128, 1950 [9] M A Krasnosel’ski˘, Positive Solutions of Operator Equations, ... linear operator in X is of course positively homogeneous and both K-superadditive and K-subadditive with respect to an arbitrary wedge K ⊆ X A characteristic example of a pair of nonlinear operators
Ngày tải lên: 22/06/2014, 18:20
Báo cáo hóa học: " Research Article Hardware Implementation of a Modified Delay-Coordinate Mapping-Based QRS Complex Detection Algorithm" potx
... the calculated areas, the block of the calculated areas is searched for all peaks above thr and all peaks between thr/2 and thr All peaks that exceed thr are automatically treated as Trang 71000 ... lowband-pass filtered ECG signal, (e) phase-space portrait of the bandband-pass filtered ECG signal, (f) calculated area of the lowpass filtered ECG signal, (g) calculated area of the bandpass filtered ... Cvikl, 1 Franc Jager, 2 and Andrej Zemva 3 University of Ljubljana, Trzaska 25, 1000 Ljubljana, Slovenia Trzaska 25, 1000 Ljubljana, Slovenia Received 30 April 2006; Revised 23 January 2007; Accepted
Ngày tải lên: 22/06/2014, 20:20
EIGENSTRUCTURE OF NONSELFADJOINT COMPLEX DISCRETE VECTOR STURM-LIOUVILLE PROBLEMS ´ RAFAEL J. doc
... an m-dimensional vector inCm,F s1, F s2, L s1, and L s2, s = 1, ,q, are matrices inCm m, not necessarily symmetric,α and γ =0 are complex num-bers, andλ is a complex parameter. Trang 4The paper ... orthogonalize the eigen-functions ofB by means of the Gram-Schmidt orthogonalization method So, we can state, without proof, the vector analogue of the Fourier series expansion in terms of an orthogonal ... into equal rectangles of sides∆x = h and ∆t = l, introduce coordinates of a typical mesh pointp =(kh, jl) and represent u(kh, jl) = U(k, j). Approximating the partial derivatives appearing in
Ngày tải lên: 23/06/2014, 00:20
Báo cáo toán học: " THE DISTRIBUTION OF DESCENTS AND LENGTH IN A COXETER GROUP" pps
... Remarks The specialization of equation (2) to q = 1 appears as [Ste, Proposition 2.2(b)], and the special case of (2) in which W is of type A n appears in slightly different form as [DF, equation ... edges of the Coxeter diagram. As a consequence, there is a universal tuple of additive statistics n1, n2, whose multivariate distribution specializes to that of any other additive statistics, ... of the fact that in the special cases of interest, expW J (x; q) will be related to a q-analogue of the exponential function exp(x), and dex WJ (x; q) will either be a product of two such q-analogues
Ngày tải lên: 07/08/2014, 06:20
Báo cáo toán học: "A probabilistic approach to the asymptotics of the length of the longest alternating subsequence" pdf
... bilateral sequence a ∈ [q]Z, we have 1 a(n) has a local maximum at k = 1 (a has a local maximum at k) + 1A k(a) , if k < n, and 1 a(n) has a local maximum at n = 1 (a has a local maximum at ... · · ak−1 = ak The identity (2) can be generalized, in a straightforward Trang 7manner to this context, so thatLAn(a) = # local maxima of a + # local minima of a = 1 (a has a local maximum at n) ... bilateral sequence a = ( , a−1, a0, a1, ) ∈ [q]Z, we say that a has a local maximum at the index k, if for some j < k, aj < aj+1 = · · · = ak > ak+1 and that a has a local minimum at
Ngày tải lên: 08/08/2014, 12:23
Tài liệu GLOBAL PHYLOGEOGRAPHY OF A CRYPTIC COPEPOD SPECIES COMPLEX AND REPRODUCTIVE ISOLATION BETWEEN GENETICALLY PROXIMATE ‘‘POPULATIONS’’ ppt
... BC, Canada; (27) Ishikari River, Japan; (28) Lake Baratoka, Japan; (29) Lake Ohnuma, Japan; (30) Lake Akanko, Japan; (31) Caspian Sea; (32) Gulf of Bothnia; (33) Gulf of Finland; (34) Saăllvik ... fiddler crabs (Uca vocator; Sturmbauer et al. 1996) and Jamaican grapsid crabs (Sesarma; Schubart et al. 1998). Sim- ilarly, separation appears to have occurred approximately 19 million years ago between ... (5 Ј GGTCAACAAAT- CATAAAGATATTGG 3 Ј ; Folmer et al. 1994) were used to obtain sequences from COI. Primer pairs 16SA2 (5 Ј CCGGGT C/T TCGCTAAGGTAG) and 16SB2 (5 Ј CAA- CATCGAGGTCGCAGTAA) were designed...
Ngày tải lên: 13/02/2014, 15:20