... great promise One of the factors that has limited more widespread use of these vaccines is the need to generate mDC in large scale Current methods for the large-scale cultivation of mDC in static ... and ease of generating DC from adherent monocytes in large scale and better purity for clinical use would be a great asset We describe a novel method of generating mature mDC in large-scale using ... roller bottles yield highly competent APC for T-cell stimulation Discussion The generation of large numbers of mature DC in a large-scale culture processes for application in vaccine clinical trials
Ngày tải lên: 11/08/2014, 10:23
... set of environmental conditions However, owing to the large amount of kinetic data required for dynamic simulation, MFA, which requires less information, has been used to manipulate large-scale ... module is capable of performing dynamic simulations as accurately as kinetic models Our hybrid method reduces the number of biochemical experiments required for dynamic models of large-scale metabolic ... quasi-dynamic simulations of large-scale metabolic pathways, while drastically reducing the number of kinetics assays needed for dynamic simulations The dynamic behaviour of metabolic pathways predicted
Ngày tải lên: 13/08/2014, 23:20
Báo cáo y học: "Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome" ppt
... the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome Addresses: * Center for Systems and Synthetic Biology and Institute for Cellular ... to establish measures of accuracy that are useful for the evaluation and integration of upcoming data-sets We established two benchmarks for assessing the quality of large-scale human protein interaction ... in spite of the incompleteness of the net-work The 'degree' of the network is defined as the average number of links per protein and captures the connectivity of the network Except for Reactome,
Ngày tải lên: 14/08/2014, 14:21
Rstoolbox - a Python library for large-scale analysis of computational protein design data and structural bioinformatics
... functions useful for the analysis of for data manipulation and conversion, comparison of de-signs with native proteins and the creation of amino acid profiles to inform further iterations of the design ... most widespread CPD tools For Rosetta, as with other similar approaches, the amount of sampling necessary scales with the degrees of freedom (conformational and sequence) of a particular CPD task ... present the rstoolbox, a Python library for the analysis of large-scale structural data tailored for CPD applications rstoolbox is oriented towards both CPD software users and developers, being easily
Ngày tải lên: 25/11/2020, 12:15
A Scalable, Decentralised Large-Scale Network of Mobile Robots for Multi-target Tracking
... sim-ulation results illustrate scalability properties of the large-scale network of mobile robots in terms of number of robots and types of scenarios Keywords: Decentralised Control, Multi-Target ... connectivities for data exchange Hence, a decentralised control for connectivity maintenance and network preservation is the key factor for large-scale networks of mobile robots for multi-target ... [3] for control of mobile robot and manipulator, has been extended to widely apply for development of the decentralised control of multi-robot systems for connectivity maintenance Synthesis of
Ngày tải lên: 21/01/2021, 04:43
simple and large scale construction of mos2 g c3n4 heterostructures using mechanochemistry for high performance electrochemical supercapacitor and visible light photocatalytic applications
... addition of an excess of MoS2 led to a decrease in photocatalytic efficiency due to the following factors First, an excess of MoS2 may poison of some of the active sites of the catalyst because of ... generation of photogen-erated charge carriers Therefore, for further verification of interfacial charge transfer and separation efficiency of the photoinduced charge carriers over the surface of the ... their large surface area, good electronic conductivity, and lightweight but their performance has been unsatisfactory due to the insufficient penetration of ions on the inert surface Therefore,
Ngày tải lên: 04/12/2022, 16:25
Báo cáo y học: " Large scale comparison of global gene expression patterns in human and mous" pot
... the global patterns of tissue-specific expression of orthologous genes are conserved in human and mouse The expression of groups of orthologous genes co-varies in the two species, both for the most ... variety of experimental and sample conditions as possible, we can gain insights into regulation at a higher level of complexity When analyzing samples from a large variety of tissues, such large-scale ... hierarchical clustering of Pearson correlation between human and mouse tissues All observations suggest that, for at least a fraction of orthologous genes, the expres-sion profiles are largely conserved
Ngày tải lên: 09/08/2014, 22:23
Báo cáo y học: " Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy" ppsx
... leading source of information for clinicians who diagnose and treat cancer The large number of samples in the database makes it ideal for sta-tistical analyses, which are capable of overcoming ... heterogeneous Trang 9set of cancers has the potential of uncovering patternsthat are related to such common mechanisms In this study we performed a large-scale analysis of karyotypes from heterogeneous ... study we present the results of large-scale analysis of chromosomal aberrations from over 15,000 karyotypes of the Mitelman Database By exploiting the huge number of karyotypes, reconstructing
Ngày tải lên: 09/08/2014, 23:20
báo cáo khoa học: " From RNA-seq to large-scale genotyping genomics resources for rye (Secale cereale L.)" pot
... touch-down PCR profile, an initial denaturation step of 15 min at 95°C was followed by 45 cycles of denaturation at 94°C for 1 min, annealing for 1 min, and extension at 72°C for 1 min. Annealing ... array for large-scale genotyping. NGS was used to generate transcriptome sequences of the five rye inbred lines Lo7, Lo152, Lo225, P87, and P105. The number of reads per sequencing run of the ... pave the way for sequencing even large genomes [47-49]. Although of major importance for research and breeding, sequence resources for rye were sparse imposing serious limita- tions for trait mapping,
Ngày tải lên: 11/08/2014, 11:21
báo cáo khoa học: " Large-scale polymorphism of heterochromatic repeats in the DNA of Arabidopsis thaliana" ppt
... article Large-scale polymorphism of heterochromatic repeats in the DNA of Arabidopsis thaliana Jerry Davison1, Anand Tyagi2 and Luca Comai*3 Address: 1 University of Washington, Department of Biology, ... USA, 2 University of the South Pacific, School of Pure and Applied Sciences, Department of Biology, PO Box 1168, Suva, Fiji and 3 University of California at Davis, Section of Plant Biology and ... [1-4] A number of methods have become available for detecting CNV, all facilitated by the availability of sequence information derived from analysis of the single or low copy fraction of the genome
Ngày tải lên: 12/08/2014, 05:20
Báo cáo y học: " Large-scale analysis of transcriptional cis-regulatory modules reveals both common features and distinct subclasses" docx
... responsible for regulating the expres-sion of a diverse set of genes in many different tissues and stages of development Here, we present the results of our first large-scale analysis of the REDfly ... properties, we recalculated the histogram of P value scores (Figure 5a) for each of several subsets of the REDfly analysis CRMs, formed on the basis of similarity of expression stages or tissue types ... degree of TFBS clustering We present here a large-scale analysis of Drosophila CRMs designed to evaluate these and other CRM properties This is the largest such study performed to-date for any
Ngày tải lên: 14/08/2014, 07:21
Báo cáo y học: "Large-scale identification of human genes implicated in epidermal barrier function" ppsx
... Conclusion: These data increase the present knowledge of genes responsible for the formation of the skin barrier and suggest new candidates for genodermatoses of unknown origin Published: 11 June 2007 Genome ... GKs Some of them, analyzed by quantitativeRT-PCR, were shown to be expressed in a cell-specific man-ner This effort resulted in a large number of novel candidategenes of importance for the epidermis ... EF-hand domains and a large domain made of repeated segments of about 25 amino acids The amino acid composition of FLG2 is very similar to that of filaggrin, with a high content of serine (22%), glycine
Ngày tải lên: 14/08/2014, 07:21
High achieving pupils’ experiences of Assessment for Learning in a mainstream junior school: a qualitative case study drawing on perspectives from psychoanalytic theories
... Reform Group before moving on to some of the writings and research complementing and challenging those arguments Practices, principles and theory of Assessment for Learning ‘Assessment for Learning’, ... responsible for their own learning Peer assessment needs to be encouraged and planned for in a ‘safe’ learning environment Arising out of these principles came this description of Assessment for Learning: ... ‘reappraisal’ of Assessment for Learning I use the term ‘reappraisal’ because one appraisal has already taken place The school’s Ofsted Report of 2002 stated that Assessment for Learning was
Ngày tải lên: 11/10/2014, 03:57
Large scale growout of spotted babylon, babylo
... view of seeking col-laborative support for the implementa-tion of some of the fi eld activities under the NACA Programme of Work These were essential preparatory actions for the establishment of ... January 1989 proposed a number of ways for obtaining external funding support One of these was for NACA to under-take the responsibility of implementing projects of international agencies like ... of interest and competence of the organization The diversity of problems in the region called for cooperative regional action for solutions The network mechanism has shown the effectiveness of
Ngày tải lên: 27/09/2019, 12:02
An approach to the large-scale integration of wind energy in Albania
... NPV comparison for the two types of turbines obtained in the study, r = 5% Figure 12: Comparison of NPV difference for the two types of turbines obtained in the study for r = 5÷7% of the park ... 1Department of Energy, Faculty of Mechanical Engineering, Polytechnic University of Tirana, Albania, 2Department of Hydraulic and Hydrotechnic, Faculty of Civil Engineering, Polytechnic University of ... price of electricity €76/MWh The results of the study highlight the importance of high levels of RES integration which not only reduces greenhouse gases but will technically favor the creation of
Ngày tải lên: 17/08/2020, 20:11
Tree reconciliation combined with subsampling improves large scale inference of orthologous group hierarchies
... challenges for large-scale OG inference faced by tree-based methods and for this reason limit their scope by subsampling the space of proteins that are part of an inconsistency beforehand Sampling ... the size (no of sequences) and the number of reconciled trees per incon-sistency To choose the used combination for the results (LS), we performed a convergence analysis of 208 large OGs at the ... in time, to more recent, fine-grained OGs, thereby spanning multiple levels of the tree of life Large scale inference of OG hierarchies with independently computed taxonomic levels can suffer from
Ngày tải lên: 25/11/2020, 12:19
Large scale analysis of protein conformational transitions from aqueous to non-aqueous media
... pairs of conformers in their unbound forms as well as in their bound form We finally obtained a total number of 1737 protein with conformers in both media (aqueous and non-aqueous) for the large ... the “large” dataset (1A) c Distributions of conformational diversity for the most populated proteins of the “control” dataset taking into account all the conformer pairs Distributions of conformational ... corresponding conformers for a given protein Therefore, we obtained three subgroups for the large dataset (AA, AO and OO with 9680, 1737, 2062 pairs of conformers, respectively) and three subgroups for the
Ngày tải lên: 25/11/2020, 15:05
Some techniques in guiding grade 12 students in large scale classes to prepare for the graduation exam in 2020 2021
... looking forward toreceiving input from all of you Thank you II RESEARCH PURPOSES. The purpose of this topic is to help grade 12 students in large-scale classeshave better understanding of tasks ... applied some techniques for students in large-scale classes namely: "Some techniques in guiding grade 12 students in large-scale classes to prepare for the graduation exam in 2020-2021". ... concerned, the Ministry of Education and training ask our provinceThanh Hoa to make efforts to improve the quality of teaching and learning sothat we can be in top 20 in the stage of 2021 to 2025 In
Ngày tải lên: 20/05/2021, 21:07
large scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy
... leading source of information for clinicians who diagnose and treat cancer The large number of samples in the database makes it ideal for sta-tistical analyses, which are capable of overcoming ... heterogeneous Trang 9set of cancers has the potential of uncovering patternsthat are related to such common mechanisms In this study we performed a large-scale analysis of karyotypes from heterogeneous ... study we present the results of large-scale analysis of chromosomal aberrations from over 15,000 karyotypes of the Mitelman Database By exploiting the huge number of karyotypes, reconstructing
Ngày tải lên: 02/11/2022, 14:23
large scale expansion of agriculture in amazonia may be a no win scenario
... average of the different types of land cover (13% for the forest, and 11% for bare land) For pastures and soybeans, albedo depends on LAI, reaching a maximum of 20% for pastures and 26% for soybeans ... of the primary forests and productivities of soybean and pastures in the Amazon under scenarios of deforestation and increased CO2concentration We evaluate the carbon storage of the primary forests ... outside the range of optimum temperature Optimum temperature range for primary forest is from 25 to 29◦C, for pasture is from 30 to 35◦C and for soybeans is from 28 to 32◦C Validation of the productivity
Ngày tải lên: 02/11/2022, 14:24