... The y-axis indicates the name of the KEGG metabolic pathways The x-axis indicates the percentage of the number of genes annotation under the pathway in the total number of genes annotation Chen ... of KOG The y-axis indicates the percentage of the number of genes annotation under the group in the total number of genes annotation Fig Functional classification and pathway assignment of unigenes ... relative humidity of 87 %, and temperatures of 30/20 °C (day/night) The plants in pots are ramets of the same clone, and the genetic background for these plants is uniform After two months of establishment,
Ngày tải lên: 26/05/2020, 22:03
... the pfDHFR and pfTS domains and the roles of the junctional region that links the two domains together Therefore, a thorough understanding of the interaction of the two domains and the role of ... Table 3, the TS activity of the pfJRTS mutants was found to decrease upon shortening the length of JR in the construct The importance of the length of the JR sequence on the activity of pfTS was ... pfDHFR-TS further confirmed the above results, and suggested that a critical length of the junctional peptide of pfDHFR-TS would be essential for the activity of TS to catalyze the synthesis of thymidylate
Ngày tải lên: 02/11/2022, 11:40
genome comparisons provide insights into the role of secondary metabolites in the pathogenic phase of the photorhabdus life cycle
... the absence of cadC in the other species CadC is a positive regulator of the cad arginine-dependent acid response system [91] The absence of enteroinva-sive E coli This absence in the other strains ... individual environ-ment Furthermore, the elucidation of the functions of products of the BGCs as well as whole genome com-parisons to the Xenorhabdus species will be important areas of future research ... Research in the Thines and Bode labs are supported by the LOEWE funding initiative of the Government of Hessen in the framework of IPF and the Thines lab is also supported by BiK-F. Availability of data
Ngày tải lên: 04/12/2022, 10:32
homoeologue expression insights into the basis of growth heterosis at the intersection of ploidy and hybridity in cyprinidae
... (1) the silencing of the C homoeologous transcripts of the mstn gene was detected in the liver of F1 and F18 and the muscle of F18 (Fig. 5) (2) Different degrees of HEB were observed in the ... the analysis of the categories of growth-related homoeologous genes, the analysis of HEB provided an insight into effect of originating from either of maternal R or paternal C, respectively The ... aligned using the reciprocal BLAST (BLASTN) hit method, with an e-value cut off of 1e−20 38 Two sequences were defined as orthologues if each of them was the best hit of the other and if the sequences
Ngày tải lên: 04/12/2022, 10:36
looking into the black box insights into the mechanisms of somatic cell reprogramming
... fully resolved The role of the BER pathway was further highlighted in the context of PGCs specification The PGCs need a profound remodeling of their genome to enable production of gametes Hajkova ... observed at the transcript level [45] However, further passaging of these iPSCs led to normalization of these epigenome differences and equalized the differentiation potential of the different ... depends on the number of cell divisions [17] They hypothesized that a low-frequency epigenetic event is required for reprogramming, therefore the number of cell cycles increases the odds of this
Ngày tải lên: 04/12/2022, 15:06
Comparative chloroplast genomes insights into the evolution of the chloroplast genome of camellia sinensis and the phylogeny of camellia
... China Full list of author information is available at the end of the article Trang 2Because of frequent hybridization and polyploidization, the mechanisms operating in the evolution of Camellia has ... 3) Mutations of the base replacement or deletion may cause changes in the length of the coding gene sequence, leading to changes in the coding and non-coding regions Therefore, the variable characters ... analysis of three types of mutation Correlations were highly significant in the pairwise Fig 3 Sliding window analysis of the complete chloroplast genomes of four tea species X-axis: position of the
Ngày tải lên: 23/02/2023, 18:21
Báo cáo khoa học: New insights into the functions and N-glycan structures of factor X activator from Russell’s viper venom pot
... sequenced Of these, 10 clones were found to encode the LC2 and LC1 sub-units Others were found to encode other variants of the C-lectin-like venom proteins The amino acid sequences of both subunits ... HC, the light chains appear to con-fer the substrate specificities of RVV-X [12] Collec-tively, the primary sequences of the three subunits of RVV-X (Figs 4 and 5) suggest the possible presence of ... systemic haemorrhage in mice These results emphasize the importance of the rapid homing of RVV-X into microvessels to exert its effect The glycan structures of a number of venom glycopro-teins have
Ngày tải lên: 07/03/2014, 06:20
Báo cáo khoa học: Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis pptx
... TS50 The analysis of the thermodynamic parameters of the different inhibitors clearly showed an increase of the afnity (decreasing of DG) of the compounds bearing the ... to the periphery of the act- ive site is restricted by the position of Arg128 from one side and the conformation of the loop connecting b4 with a3 (residues 85–88) from the other side. In the ... occupy the same posi- tion in spite of the different conformation of the alkyl chain. The positions of the four hydroxyl oxygen atoms of the ribityl chain are occupied by four water molecules in the
Ngày tải lên: 07/03/2014, 11:20
Báo cáo khoa học: New insights into the P-glycoprotein-mediated effluxes of rhodamines doc
... in the cytosol This observation allows the further determination of the concentration of drug free in the cytosol of resistant cells The determination of karequires also the measurement of the ... the rate of passive diffusion of the dye through the plasma membrane This cannot be done by the simple measurement of the increase of the fluorescence signal (Fcyto) of the cells when they are ... line K562,in the absence of membrane potential,the gradient of rhodamine concentration gener-ated by the presence of the pump,the free intracellular rhodamine concentration,the rate of their passive
Ngày tải lên: 08/03/2014, 08:20
Báo cáo y học: " Draft genome sequence of the Daphnia pathogen Octosporea bayeri: insights into the gene content of a large microsporidian genome and a model for host-parasite interactions" pps
... rather than the size of the genome in which they are found Evidence for the progressive loss of ancestral genes throughout the evolution of the microsporidian lineage Prior to this study, the ... within the group is also variable The wealth of genomic data from this parasite cou-pled with the annotation of the Daphnia genome should Trang 3fur-ther increase the interest for this model of ... [14-24] The extremely reduced nature of microsporidian genomes has attracted attention since they were first noted at the end of the 1990s [13], culminating in 2001 with the completion of the first
Ngày tải lên: 09/08/2014, 20:20
báo cáo khoa học: " Construction of a potato consensus map and QTL meta-analysis offer new insights into the genetic architecture of late blight resistance and plant maturity traits" pps
... on the other hand QTL names are written to the left of the bars QTL nomenclature is as follows: the name of the first author of the original publication juxtaposed to the last two digits of the ... complete view of the genetic architecture of the trait with the distribution of the involved loci along the genome This synthesis can be greatly facilitated by achieving a QTL meta-analysis The general ... Number of integrated individual chromosome maps Figure 1 Characteristics of the consensus potato map For each of the 12 potato chromosomes, the bar represents the total number of markers, the upper
Ngày tải lên: 11/08/2014, 11:21
Mechanical insights into the physiological functions of claudin mediated adhesion at tight junctions b
... contact force of 200 pN and contact time of ms were used, b25% of the force–distance curves showed bond rupture events. On the basis of Poisson statistics,25 the low frequency of these de-adhesion ... dissociation of bounded complex. The geometry of the conceptual energy landscape for the dissociation pathway can be constructed based on these kinetic parameters. The geometric locations of their bound ... difference of the outer barrier. The effect of different activation energy barriers on the dynamic properties of Cldn2/Cldn2 and C2E1/ C2E1 complexes is best illustrated in the comparison of their
Ngày tải lên: 11/09/2015, 16:05
Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx
... well as of the alleviation of this inhibition by another substrate of the enzyme, ATP, are presented [8,9] Results Solution properties of the N-terminal domain of PS, the C-terminal domain of PS, ... regions of the Ramachandran map [32,33] Comparison of the monomer of the substrate-free form of E coli PS [13] with the monomers of nPS in the pantoate-bound form at full occupancy indicates that the ... back to the position of the Fig Superimposition of the A-chain of nPS (green), the B-chain of nPS (cyan), and the substrate-free protein (1IHO.pdb; magenta) The carbon and oxygen atoms of pantoate...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt
... of the PpNp The financial support of the Kultusministerium des Landes Sachsen-Anhalt and the Graduiertenkolleg 1026 of the Deutsche Forschungsgemeinschaft, Bonn (Germany), and the support of the ... in the typical range for a spherical particle The bell-shaped distance distribution function illustrates the quality of the experimental data (Fig 2B) Reconstruction of the overall shape of the ... occupy 16% of the molecular volume, and therefore seems too large to represent the lid-like structure at the top of the left view in Fig We speculate that the loosely structured region on the opposite...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khóa học: Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b pdf
... the left side of the blots The Western blots are shown in panels A and B and the relative amounts of each of the subunits determined by densitometry scanning of the stained Western blots of the ... protein to insert into and be stable in the inner mitochondrial membrane or lack of detection of the truncated protein by the antibodies In the W303–1B q° strain the amounts of the other two catalytic ... the absence of subunit also resulted in an increase in the ratio of intermediate to mature cytochrome c1 and a disappearance of the intermediate form of the Rieske protein At the same time, the...
Ngày tải lên: 19/02/2014, 12:20
Click Here: The State of Online Advertising - New insights into the beliefs of consumers and professional marketers ppt
... 44% of consumers feel advertising works better on women than men Professional advertising is the most effective form of advertising, 27% of marketers believe that user-generated content is the ... Visit the product's website 11% Visit the product's social media page Other 6% Like' the product 5% 'Comment' on the product 4% Hide that person from your social media newsfeed 2% Recommend the ... popular form of online advertising Advertising/Marketing professionals considered in the bottom professions among consumers – along with actors and dancers; not highly regarded by marketing professionals...
Ngày tải lên: 15/03/2014, 22:20
Báo cáo khoa học: Insights into the activation of brain serine racemase by the multi-PDZ domain glutamate receptor interacting protein, divalent cations and ATP ppt
... concentrations of the substrate l-serine in the absence of additional ATP (Fig 3C) We were able to determine that binding of this fragment of GRIP to SR changed both the Km and the Vmax of the reaction The ... interactions in the presence and absence of the nucleotide According to our results, the absence of modulation of the oligomeric state of the enzyme by the nucleotide is in clear contrast with the behaviour ... results in the decrease of the Km for threonine from 70 mm in the absence to mm in the presence of this cofactor [20] At the same time, binding of AMP to E coli threonine dehydratase results in the...
Ngày tải lên: 30/03/2014, 03:20
Báo cáo khoa học: Insights into the design of a hybrid system between Anabaena ferredoxin-NADP+ reductase and bovine adrenodoxin pot
... to the changes introduced in the redox cofactor environment upon complex formation They are therefore related to the specificity and the strength of the protein–protein interaction Therefore, the ... point out the different arrangement of the [2Fe)2S] centres of these Fds The cyanobacterial Fd presents an increased shielding from the solvent of the active Fe in ET when compared with that of Adx ... represents the initial rate of the reaction, vs the Adx concentration shows an almost linear correlation (Fig 3A), suggesting that the formation of the optimal complex between the two proteins limits the...
Ngày tải lên: 31/03/2014, 07:20
Báo cáo y học: "omparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi" pps
... the comparison of the two genome sequences revealed a strong similarity Using the software Mummer [22], approximately 21.8 Mb of the genomes (98.0% of the available A benhamiae and 96.7% of the ... each other, indicating that the vast majority of genes lie in collinear regions and are shared between the two organisms The average identity of the alignable portion of the genomes is 94.8% The ... by the possession of a broad repertoire of genes encoding hydrolytic enzymes, the expression of many of which was also proven experimentally (see the next paragraph and the ‘Identification of...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo y học: "Structural insights into the function of the core-circadian factor TIMING OF CAB2 EXPRESSION 1 (TOC1)" ppt
... module of TOC1 This further supports the phylogeny relations of the amino-terminal module of PRR to genuine RRs [40] In each of the four TOC1 modules, an Ala is present at what is the Asp site of ... an axis of the ROOT MEAN SQUARE DEVIA- TION (RMSD) of the resultant structures [36] From there, each of the related four proteins of each module was processed on SPATIAL ARRANGEMENT OF BACKBONE ... The signaling nature of the encoded rhythmic Ca2+ is an active area of investigation [25,27,28], and the receptor for this Ca2+-derived signal is as of yet unknown One point of note is that the...
Ngày tải lên: 10/08/2014, 09:20