genetic basis of biological sexuality

... introgression of a small fraction of the wild genome species while keeping the genetic background of the cultivated is a good mean to explore the largely untapped reservoir of useful alleles of interest ... construction of a tetraploid molecular genetic map using a BC1F1 population and the develop-ment of a BC2F1 population allowed the analysis of the introgression of wild alleles in the background of a ... cultivated variety provided a set of lines offering an optimal distribution of the wild introgressions Conclusion: The genetic map developed, allowed the synteny analysis of the A and B genomes, the

Ngày tải lên: 12/08/2014, 03:21

... 1ELUCIDATING THE GENETIC BASIS OF SEVERE OBESITY: LEARNING FROM THE EXPERIMENTS OF NATURE LEE YUNG SENG Trang 2ELUCIDATING THE GENETIC BASIS OF SEVERE OBESITY: LEARNING FROM THE EXPERIMENTS OF NATURE ... of Cys28Phe and Leu37Phe B) Co-segregation of C28F and L37F with overweight/obesity in families 92 93 4-3 Structure of POMC and location of mutations 95 4-4 Sequence alignment of N-terminus of ... genes of this cohort were screened by direct sequencing The POMC gene of more than 900 DNA samples from the Genetics of Obesity Study (GOOS) (Cambridge, UK) were screened using a combination of

Ngày tải lên: 11/09/2015, 09:02

... impact of a family history of diabetes; to further assess the genetic basis of type diabetes, we next examine the contribution of recently identified novel T2DM susceptibility loci on the risk of ... The genetic basis of Type diabetes in a multi-ethnic population in Singapore. Jonathan Tan Tze Chong (B.Sc (Hons I)) Submitted for the degree of Doctor of Philosophy Department of Epidemiology ... Abbreviations • Introduction • Background • 7.1 Pathogenesis of type diabetes • 7.2 Heritability of type diabetes • 10 7.3 The complexity of the genetics of type diabetes • 12 7.4 Direct versus indirect

Ngày tải lên: 14/09/2015, 08:48

... N/ha) may also explain the low NUE of rapeseed [4] From an agronomic point of view, the improvement of the NUE can be assessed by the increase of seed yield per unit of N fertilizer [5, 6] Hence, ... lack of evidence suggests that there is room to improve the understanding of the genetic control of NUE and yield stability across N nutrient conditions in rapeseed Gaining insight into this genetic ... study of the G × N interac-tions Nevertheless, the genetic determinants of thesetraits have hardly been studied to date [28] The aims of the present study were to obtain a prehensive overview of

Ngày tải lên: 27/03/2023, 03:18

... integral part of, has a biological focus, often in the form of drugs or surgery Nurses today, as clinical specialists, are taking on more advanced work, often in areas previously thought of as being ... decisions quickly andaccurately The Biological Basis of Nursing: Clinical Observations integrates clear explanations of the techniques involved in these procedures withthe biological knowledge which gives ... Mechanism of the large urine loss (diuresis) in 5.9 Mechanism of aldosterone action 105 5.10 The natural history of bilirubin 108 6.2 Stimulation of the vomit centre 124 6.3 Vestibular stimulation of

Ngày tải lên: 22/03/2014, 22:20

... in our community of friends But it is not so for all of us Genetics, accident, the "luck of the draw"—all of this can play against us in our later years, depriving us of the ability to ... isolation of many elderly people T h e all loss of the ability to control the image of ourselves seen by others may be one of the most devastating changes of growing old, ranking with the fear of death ... moment of birth, a con-stant proportion of the surviving members of the selected cohort will die T h e shape of this curve of course could be altered somewhat if, for example, older members of the

Ngày tải lên: 11/06/2014, 05:26

... of a trait for a young bull from the ith group of origin, in the jth contemporary group and progeny of the kth sire; Oi was the fixed effect of the ith group of ... equivalent to the genetic variability of live growth traits and therefore slightly inferior to the genetic variability of carcass composition traits; about 30% of the observed ... J R Stat Soc B 39, 1-20 Dickerson GE (1982) Effect of genetic changes in component of growth on biological and economic efficiency of meat production In: 2nd World Congr on Genet Appl

Ngày tải lên: 09/08/2014, 18:21

... Economou, MD, PhD Beaumont Professor of Surgery Professor of Microbiology, Immunology, and Molecular Genetics Professor of Medical and Molecular Pharmacology University of California—Los Angeles ... Professor Department of Surgery Jacobs School of Medicine and Biomedical Sciences University of New York—Buffalo Buffalo, New York Terry C Lairmore, MD Professor of Surgery Director, Division of ... Assistant Professor of Surgery Department of Surgery University of Virginia Charlottesville, Virginia Thomas Gillispie Smith III, MD Assistant Professor Scott Department of Urology Baylor College of Medicine

Ngày tải lên: 06/09/2019, 16:19

... Ferrucci 8. BIOLOGICAL SCREENING AND IMPACT IN ELDERLY Anne-Chantal Braud and Martine Extermann 9. BIOLOGICAL BASIS OF THE ASSOCIATION OF CANCER Martine Extermann 10 BIOLOGICAL BASIS OF CANCER ... ISBN 0-387-23603-1 Trang 5BIOLOGICAL BASIS OF GERIATRIC ONCOLOGYedited by LODOVICO BALDUCCI, MD Professor of Oncology and Medicine University of South Florida College of Medicine Program Leader, ... administration of full doses oftreatment These provisions include prophylaxis of neutropenicinfections, avoidance of severe anemia, timely management ofmucositis, and provision of adequate home

Ngày tải lên: 07/09/2020, 08:42

... extent of staining found in the nucleus was considered positive The staining of c-myc and cyclin D1 was assessed on the basis of published data: negative (< 10% of the cells), and positive (> 10% of ... level of key signaling pathways affected by these genetic aberrations The most surprising and intriguing finding was the deletion of Wnt pathway genes, suggesting the genetic inactivation of the ... Identification of prognosis markers and key genetic and molecular events for osteosarcoma is critical for development of effective therapeutics [2,3] Fortunately, the discovery of signal transduction

Ngày tải lên: 14/10/2020, 17:21

... combining population genetic analyses with biological insights provides a description of the Italian genetic structure that in future could contribute to the evaluation of complex diseases risk ... Understanding the genetic structure of human popula-tions is crucial to reconstruct their history and to elucidate the genetic predisposition to diseases In fact, the genetic structure of human populations ... diabetes genetic risk moving out of Africa [3] or the demonstration that common risk alleles for inflammatory diseases are targets of recent positive selection [4] Therefore, the study of the genetic

Ngày tải lên: 27/03/2023, 05:18

... Search for the Genetic Material of Life  What is a gene?  Stable source of information  Ability to replicate accurately  Capable of change Trang 2The Search for the Molecular Basis of Heredity ... Model of DNA Two sources of information: 1 Base composition studies of Erwin Chargaff • indicated double-stranded DNA consists of ~50% purines (A,G) and ~50% pyrimidines (T, C) • amount of A ... pyrimidines (T, C) • amount of A = amount of T and amount of G = amount of C Trang 15James D Watson & Francis H Crick - 1953Double Helix Model of DNA Two sources of information: 2 X-ray diffraction

Ngày tải lên: 13/03/2014, 16:34

... Richard W. Titball 1 1 Biosciences, College of Life and Environmental Sciences, University of Exeter, UK 2 Department of Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck ... various organs of toxin-injected mice dem- onstrated specific, displaceable binding of GFP-tagged toxin to blood vessels of the brain and to distal tubules of kidneys [49]. Specific binding of GFP-tagged ... stim- ulates release of dopamine from dopaminergic nerve endings [57]. In another study, prior injection of either a presynaptic glutamate release inhibitor or a Molecular basis of toxicity of C. perfringens

Ngày tải lên: 14/03/2014, 22:20

... lasting memories of the opening ceremony in the opera house, which was initiated by the fanfare of Janacek’s Sinfonietta This is one of the reasons why when I think of Prague I also think of music In ... structure of the extracellular ligand-binding domain of a number of these receptor complexes has now been elucidated, providing the molecular basis for understanding the func-tional relevance of mechanistic ... storage and realization of genetic information As a sounding illustration of this topic, one of the Brandenburg Concertos was played and in parallel the single pages of the partitur, the musical

Ngày tải lên: 15/03/2014, 09:20

... Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA 2 Department of Environmental and Occupational Health, Graduate School of Public Health, University of ... for the genetic basis of b2GPI plasma variation, but the exact molecular basis of this variation remains largely unknown b2GPI is suggested to regulate thrombin inactivation by heparin cofactor ... University, Feinberg School of Medicine, Division of Rheumatology, Chicago, IL, USA 4 Division of Rheumatology and Clinical Immunology, Lupus Center of Excellence, University of Pittsburgh, Pittsburgh,

Ngày tải lên: 15/03/2014, 10:20

... Provincial of the Missouri Province of the Society of Jesus, in virtue of faculties granted to him by Very Rev L MARTIN, General of the same Society, hereby permits the publication of a book entitled ... opening of this new year of studies, of the excellence of your intended profession; for you cannot help seeing that a science so noble should be studied for a noble purpose In this age of utilitarianism, ... the Prospectus of this College to a gentleman of the legal profession He will acquaint you with the laws of the land, and of this State in particular, which regulate the practice of medicine; he

Ngày tải lên: 15/03/2014, 13:20

... sequences analyzed The analysis of the predicted structure suggested that the presence of the shorter lateral chain of Val311 instead of Leu allows for the movement of Tyr239 and Glu309 towards ... PGKs, because of their higher levels of Table 1 Nucleotide specificities of E histolytica and S cerevisiae PGKs in cytosolic-enriched cellular extracts Values represent the mean ± SD of titrations ... structure of EhPGK (A) Overlapped structures of the pig PGK crystal structure with ATP (1KF0; green) and E his-tolytica PGK predicted model with GDP (red) obtained using MOE software (B) Close up of

Ngày tải lên: 16/03/2014, 01:20

... it is often claimed (e.g., Depew and Weber 1998) that the nor- mativity of biological functions can be fully naturalized in terms of Wright’s (1998) analysis, in which a function is a part of a ... sense. Of course, science often looks to history to explain how the present state of a system came into being, but the present causal powers of a system must nevertheless be explicable in terms of ... stability of the oscillator. This dynamical interpretation of semantic information provides us with a new physical picture of the cognitive component of adaptive functional action. Most, if not all, of...

Ngày tải lên: 01/11/2013, 08:20

... molecular mode of action of glypho- sate and the molecular basis for glyphosate resistance. Structure and function of EPSPS EPSPS catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate ... 4% of the total soluble protein content of the cell [48]. Fig. 3. Microbial mechanisms of glyphosate degradation. (A) Two principal pathways of glyphosate degradation are known. Top: cleavage of ... however, was devoid of substrate or inhibitor, and consequently did not reveal the nature of the active site or the mode of action of glyphosate. A dec- ade later, the crystal structure of EPSPS was...

Ngày tải lên: 14/02/2014, 14:20

... have a high prevalence of sexual dysfunction, some of which is medication-induced, some of which is illness-induced, and some of which is simply part of the difficulties of living. 4. El-Defrawi, ... my partner? How Handbook of Clinical Sexuality for Mental Health Professionals Jeffrey W.Janata, PhD is Assistant Professor in the Department of Psychiatry and Director of the Behavioral Medicine ... of the Department of Forensic Medicine in the University of Ulm in Germany S.Michael Plaut, PhD is Assistant Dean for Student Affairs and Associate Professor of Psychiatry at the University of...

Ngày tải lên: 15/02/2014, 02:20