... tourism production, is that in the tourism industry, customers are brought to the product, not the other way around Unlike the distribution of physical goods, in travel and tourism, distributors ... or whether firms should “direct sell” to the customer There is an inevitable trade-off in losing control to the intermediary The three intermediary options differ in the degree of control they ... distribution, we consider the GDS as the supplier to the travel agent; GDSs have tried to capture as much of the travel agencies as possible in order reach the greatest number of customers Finally, exclusive
Ngày tải lên: 16/04/2022, 12:40
... static (the distance from the surface of the ground to the water level inside the well, located about 12m from the surface) and the second, a dynamic level (the distance between the surface of the ... near the coast, below the southernmost point of the island (in SW-8, 10 and 11), the pattern is the opposite The winds from the north quadrant were the most frequent and stronger than the southerly ... growth There is a decadal pulse of sediment inputs to the system, as well The northern sector of Santinho beach has a positive budget and provides about 6,000m³/year of sediment to the foredune Then,
Ngày tải lên: 13/10/2022, 15:52
pwc-gmc-the-future-of-asean-time-to-act
... Trang 1The Future of ASEAN Time to ActPwC Growth Markets Centre The Future of ASEAN – Time to Act Trang 2ASEAN - A Unique Growth StoryThe year 2017 marked the 50th anniversary of ASEAN, (the Association ... Similar to the case in other developing parts of the world, infrastructure limitations continue to slow the pace of growth in these ASEAN economies Significant gaps exist across a range of sectors, ... questions about the sustainability of ASEAN’s growth story Underlying these challenges is the fact that the share of population aged 65 and older is projected to reach close to 2.5 times the current
Ngày tải lên: 28/10/2022, 00:31
Internal Audit 2012*: A study examining the future of internal auditing and the potential decline of a controls-centric approach docx
... seen as the technical domains solely of internal audit or other staff functions Management as well has begun to take ownership of risk to the business and of ensuring the effectiveness of the controls ... beneficial to develop a consensus projection of the trends likely to shape the world of internal audit by the year 2012 This report is the result of that effort, and we are deeply grateful to those ... and to formally document their internal control activities The Act also provides the impetus for many companies to formalize their approach to the management, monitoring, and testing of internal
Ngày tải lên: 23/03/2014, 04:20
Báo cáo khoa học: Common mode of DNA binding to cold shock domains Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus pot
... with the nucleobases pointing towards the protein surface The 5¢-to-3¢ polarity of the ligand follows that of most other nucleic acid com-plexes of OB-fold proteins, starting in the vicinity of ... association of subdomains results in the formation of the closed b barrel burying the hydrophobic core At present there is no experi-mental evidence for the occurrence of the domain-swapped form of Bc-Csp ... A˚2) The Bc-Csp domain swap provides insight into the folding and misfolding of the CSP The Bc-Csp domain swap occurs in the middle of loop L34 and is promoted by a unique combination of torsion
Ngày tải lên: 23/03/2014, 09:21
The Economic Impact of Rail Improvements to the Port of Corpus Christi, Texas pptx
... of the United States, there exists a need to expand portions of the Port of Corpus Christi both in terms of capacity and efficiency In order to adequately expand the Port of Corpus Christi to ... earlier, the magnitude of the economic impacts of these activities is largely related to the degree to which industries within the local area are able to supply needed inputs As expected, the state ... operation of the improved rail infrastructure then must purchase their respective inputs to support the improvement of the rail infrastructure; these are known as indirect effects Those who work in the
Ngày tải lên: 23/03/2014, 21:20
Application of serum proteomics to the Women’s Health Initiative conjugated equine estrogens trial reveals a multitude of effects relevant to clinical findings pot
... minutes. A total of 12 pools were collected from the anion exchange chromatography. The 12 pools were then subjected to a second dimension of separation by reversed- phase chromatography. The reversed-phase ... in a small volume of 2 M Tris-HCl pH 8.5 [19]. For each of the five experiments, the pool of baseline (C12) and estrogen-treated (C13) samples was then mixed together for further analysis. PPrrootteeiinn ... allows identification of proteins over seven orders of magnitude of abundance to determine the effect of oral CEE on the serum proteome [19-22]. A prior proteomic study of hormone therapy-relevant
Ngày tải lên: 28/03/2014, 14:20
Đề tài " Existence and minimizing properties of retrograde orbits to the three-body problem with various choices of masses " potx
... methods on the existence ofcertain types of solutions to the planar three-body problem with various choices of masses There is a natural way of classifying orbits by their topologicaltypes in the configuration ... relative period of x is the prime period of ˜x Our major result concerns the existence of relative periodic solutions to the three-body problem that are homotopic to α φ in V \Δ respecting the rotation ... orbits inthe lunar theory Detailed descriptions are left to Section 2 and 3 Our maintheorem (Theorem 1) shows the existence of many periodic and quasi-periodicretrograde solutions to the three-body
Ngày tải lên: 29/03/2014, 07:20
Báo cáo khoa học: Catalytic activation of human glucokinase by substrate binding – residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions ppt
... revealed the structures of the unliganded (super-open) and Glc-bound (fully-closed) states of hGK [12], the residue contacts that make essential tributions to the binding of Glc to the super-open ... and the GST fusion proteins were therefore used alterna-tively in the studies of mutant proteins due to their potentially higher in vitro stability To better under-stand the driving force of the ... site residues involved in the binding of Glc to the super-open state (Fig 1C) of this two domain [large (L) and small (S)] enzyme, and thus the site of initia-tion of the global conformainitia-tional
Ngày tải lên: 30/03/2014, 04:20
Báo cáo khoa học: Identification of the epitope of a monoclonal antibody that disrupts binding of human transferrin to the human transferrin receptor pptx
... restricted to a surface patch of hTF consisting of residues 365–385 Mutagenesis of the F11 epitope of hTF to the sequence of either mouse or pig TF confirmed the identity of the epitope as immunoreactivity ... Discussion The present study establishes that the epitope of the F11 antibody is in the C-lobe of hTF, specifically within residues 365–401 of the C1 domain Further-more, binding of the F11 antibody to ... to residues 365–385 of the hTF C-lobe The mAb F11 blocked binding of hTF to the TFR; this suggests the antibody epitope contains residues that are located in the vicinity of the ligand–receptor
Ngày tải lên: 30/03/2014, 11:20
edinburgh university press the future of multicultural britain confronting the progressive dilemma oct 2008
... into a mandate for the rightward shift of the. .. what means, would they assert the rights of the violated? How would they speak in the defence of the victims, and how would they ... credited to the expression of Hindu dharma and the glory of the Hindu rashtra (nation) In Breaking the Spell of Dharma she documents some of the attempts by the VHP to ‘Hinduise’ ... (science) at the site of the explosion The temple was to celebrate the Vigyan of the Vedas, which, supposedly, contain all the science of nuclear fission and all the know-how
Ngày tải lên: 11/06/2014, 12:43
Legislative Audit Division State of Montana Report to the Legislature December 2004 Financial_part1 ppt
... University-Billings consists of five colleges: the College of Arts and Sciences, the College of Business, the College of Education and Human Services, the College of Technology, and the College of Professional ... furnished to us, and our opinion, insofar as it relates to the amounts included for the audited component units of the university, is based on the reports of the other auditors We conducted our audit ... audit and the reports of other auditors provide a reasonable basis for our opinion In our opinion, based on our audit and the reports of other auditors, the financial statements referred to above
Ngày tải lên: 18/06/2014, 20:20
Legislative Audit Division State of Montana Report to the Legislature December 2004 Financial_part2 pot
... the Board of Regents in the amount of $28.0 million Enhancements include renovation of the student union building, construction of a theater, and renovation of the health and P.E complex The University ... added to the existing pledged revenues of the University’s bonded indebtedness and will be used to fund debt service requirements Also in November, the Board of Regents authorized the issuance of ... to issue bonds to fund approximately $25.0 million of the project, with the use of existing resources funding the remainder Increased student fees will be implemented beginning in the Fall of
Ngày tải lên: 18/06/2014, 20:20
Legislative Audit Division State of Montana Report to the Legislature December 2004 Financial_part3 docx
... securities in the future During the period the securities are on loan, the Board receives a fee and the custodial bank must initially receive collateral equal to 102 percent of the market value of the ... units, and the reporting entity is entitled to, or has the means to otherwise access, a majority of the economic resources received or held by the separate organization The resources of the separate ... of the markets in which the related underlying assets are traded Credit risk is the possibility that a loss may occur due to the failure of a counter party to perform according to the terms of
Ngày tải lên: 18/06/2014, 20:20
Legislative Audit Division State of Montana Report to the Legislature December 2004 Financial_part4 ppt
... unit of the State of Montana) Notes to Consolidated Financial Statements As of and for Each of the Two Years Ended June 30, 2004 (continued) A - 27 Total, all series Payable during the ... unit of the State of Montana) Notes to Consolidated Financial Statements As of and for Each of the Two Years Ended June 30, 2004 (continued) A - 26 Series 1996 D Payable during the year ... (a component unit of the State of Montana) Notes to Consolidated Financial Statements As of and for Each of the Two Years Ended June 30, 2004 (continued) A - 24 Historical records are
Ngày tải lên: 18/06/2014, 20:20
Legislative Audit Division State of Montana Report to the Legislature October 2005 Financial_part1 ppt
... invested, to carry the estimated cost of all claims to maturity, to meet the reasonable expenses of conducting the business of the New Fund, and to maintain an excess of surplus over the amount ... report on the Financial audit of the Montana State Fund, a component unit of the State of Montana, for the fiscal year ended June 30, 2005 The objectives of this audit include determining if the financial ... authorized the custodial bank to leilcl MSF's securities to broker-dealers and other entities with a simultaneous agreement to return1 the collateral for the saine securities in the future State
Ngày tải lên: 18/06/2014, 20:20
Tài liệu THE ENCYCLOPEDIA OF HOLLYWOOD: AN A TO Z GUIDE TO THE STARS, STORIES, AND SECRETS OF HOLLYWOOD docx
... either be paid or negotiated before the film goes into production These generally consist of the cost of acquiring rights to the property to be filmed (the novel, play, concept, etc.), the cost of ... into a movie, the overall quality of such adaptations has not been good The fact is, the better the novel, the less likely it is to be made into a great movie The unique elements of the novel the ... the BIOPIC The Story of Alexander Graham Bell (1939) The movie was so successful and the actor became so identified by the public with his role as the inventor of the telephone that a phrase of...
Ngày tải lên: 19/02/2014, 10:20
The Future of Manufacturing Opportunities to drive economic growth docx
... of the project, the objective was to create a “data-driven narrative” regarding the state of the global manufacturing ecosystem and the factors that would be most likely to shape the future of ... assembling toys to assembling televisions than to jump from textiles to aerospace They call the feasibility of these jumps “adjacent possibilities.” In their maps of the industrial landscape of a nation, ... interests and jobs Five of the top seven sectors and 15 of the top 20 sectors most affected by discriminatory policy measures around the world are manufacturing sectors Some of the heaviest hit include...
Ngày tải lên: 17/03/2014, 08:20
scientific american special edition - 1999 vol 10 no1 - the future of space exploration
... BEAUTY of a night liftoff of the shuttle Endeavour ew sights are as awe-inspiring as the liftoff of a space shuttle Propped on its pair of solid-rocket boosters, the shuttle towers over the launchpad ... 2004 the Stardust spacecraft will plunge into the coma — an immense cloud of dust and gas — surrounding the nucleus of Comet Wild The Whipple shields at the front of the spacecraft will protect the ... exploration of the surface With a 12-ton stockpile of fuel for these trucks, the astronauts can travel more than 24,000 kilometers during their stay, giving them the kind of mobility necessary to conduct...
Ngày tải lên: 12/05/2014, 16:24
The future of air travel
... AND PROFITS THROUGH THE INTEGRATED USE OF CUSTOMER DATA [THE FUTURE OF AIR TRAVEL [ “If the airlines don’t re-strategise and become either travel facilitators or solution providers to the problems ... airlines to better understand and, thus, offer more of what customers want IMPROVED PERSONALIZATION AND PROFITS THROUGH THE INTEGRATED USE OF CUSTOMER DATA [THE FUTURE OF AIR TRAVEL [ Improving the ... the previous year by 50%, according to the Journal The company’s stock price and profits doubled IMPROVED PERSONALISATION AND PROFITS THROUGH THE INTEGRATED USE OF CUSTOMER DATA [THE FUTURE OF...
Ngày tải lên: 04/12/2015, 00:23