... shock protein; IAP, inhibitor of apoptosis protein; JNK, Jun kinase; PI, pyridine iodination; Smac, second mitochondria-derived activator of caspase. Trang 2mitochondrial protein, second mitochondria-derivedactivator ... fractions was determined by immunoblot analysis Mitochondrial protein cytochrome oxidase subunit II was used as a marker of mitochondrial protein and Ponceau S staining was used as the loading control ... conditions, HSP70DATP-BD over-expression abolished the function of full-length HSP70 (P < 0.05) No toxic effects were observed after transfection with the vectors described above Discussion
Ngày tải lên: 16/03/2014, 01:20
... for quantitative analysis of phosphorylation effects mediated via SH3domain interactions In a pulse-chase assay, active Fyn and recombinant PAG were incubated on ice with a low concentration of ... observation may indicate an increase in PPII conformation caused by stabilization of the proline-containing peptide upon binding to the SH3-domain [34] Ligand binding over a concentration range ... [46] In vivo manipulation of protein interaction domains in this way could provide valuable insight into the functional consequences of localized protein–protein interactions As an example, the
Ngày tải lên: 24/03/2014, 00:21
Báo cáo khoa học: Alanine screening of the intracellular loops of the human bradykinin B2 receptor – effects on receptor maintenance, G protein activation and internalization pdf
... mutations in ICL-3 resulted in receptor conforma-tions that were considered to be semi-active, based on the observation that they responded with phosphoinositide hydrolysis to compounds normally considered ... [16], we took care to use nonsaturating con-centrations of less than 2 nm [3H]BK Under these con-ditions, none of the constructs exhibited significantly slower internalization than that observed for ... mutation 3⁄ 4 and point mutation T242A in ICL-3, in contrast, resulted in semi-active receptor conformations, as these expressed constructs gave a clear response to these otherwise poor partial agonists
Ngày tải lên: 29/03/2014, 23:20
Báo cáo y học: "A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database" ppt
... comparisons of phosphorylation patterns found under different conditions The database also contains the largest available collection of atomic models of phosphorylatable proteins Detailed analysis ... exposed and buried versions could exist, depending on the conformational states of the proteins The latter included the active and auto-inhibitory conformations of human tyrosine-protein kinase c-Src ... conformational changes upon phosphorylation (mitogen-activated protein kinase [30] and ubiquitin-protein ligase E3 [31]) In both cases the structural rearrangements are critical for activation
Ngày tải lên: 14/08/2014, 07:21
Báo cáo sinh học: " Genetic parameters for social effects on survival in cannibalistic layers: Combining survival analysis and a linear animal model" pdf
... correlations as LAM Furthermore, cross validation showed that selection based on both direct and associative genetic effects, using either 2STEP or LAM, gave the best prediction of survival time Conclusion: ... therefore, a generalisation of the conventional h2 to account for social interactions Cross validation We compared 2STEP to LAM using cross validation [35] With cross validation, known phenotypes ... Authors ’ contributions EDE performed the data analysis and the cross validation, wrote and prepared the manuscript for submission VD helped with the data analysis and cross validation and reviewed
Ngày tải lên: 14/08/2014, 13:21
Temperature effects on bioelectrical impedance analysis (BIA) used to estimate dry weight as a condition proxy in coastal bluefish
... composition or condition that could identify areas of population stress, pollu-tion, or competition However, such studies are currently limited by our reliance upon measures of condition that ... associated content indicates your acceptance of BioOne’s Terms of Use, available at www.bioone.org/page/terms_of_use Usage of BioOne content is strictly limited to personal, educational, and non-commercial ... http://www.bioone.org/doi/full/10.1080/19425120.2011.603961 BioOne ( www.bioone.org ) is a nonprofit, online aggregation of core research in the biological, ecological, and environmental sciences BioOne
Ngày tải lên: 04/09/2015, 12:51
Expression of neurogranin tagged with enhanced green fluorescence protein in HEK293 cells and its effects on neuronal signaling
... acid protein The RC3/Ng gene consists of four exons and three introns The first exon contains the entire 5’-untranslated region and those coding for the N-terminal 5 amino acid; the second contains ... transduction pathways at the postsynapses Trang 161.4 Thyroid hormone regulation of Ng expression Ng is among the few known neuronal genes whose expression can be influenced by thyroid hormone level ... both proteins were present as phosphoproteins and phosphorylated Ng was around 73% of the total 2.5.2 Relationship between Ng phosphorylation and Long-term potentiation (LTP), Long-term depression
Ngày tải lên: 05/10/2015, 22:32
Expression of neurogranin tagged with enhanced green fluorescence protein in HEK293 cells and its effects on neuronal signaling
... acid protein The RC3/Ng gene consists of four exons and three introns The first exon contains the entire 5’-untranslated region and those coding for the N-terminal 5 amino acid; the second contains ... transduction pathways at the postsynapses Trang 161.4 Thyroid hormone regulation of Ng expression Ng is among the few known neuronal genes whose expression can be influenced by thyroid hormone level ... both proteins were present as phosphoproteins and phosphorylated Ng was around 73% of the total 2.5.2 Relationship between Ng phosphorylation and Long-term potentiation (LTP), Long-term depression
Ngày tải lên: 06/10/2015, 20:35
INTERNATIONAL BUSINESS MANAGEMENT ANALYSIS AND EVALUATION ON EFFECTS OF “BAC KAN SOFT IRON PRODUCTION FACTORY” PROJECT
... studentfocuses on researching and evaluating an important perspective of the project whichis “effects of the project” 1 Name of thesis: Analysis and evaluation on effects of “Bac Kan soft iron production ... considered as high economicaleffective ones, but actually after being completed and going into operation, theyface to great losses What is reason? In my opinion, the main reason is that theanalysis ... and analysis on market, collect actual information, treat dataand use database of consulting services in the technical field 4.2 Offer conclusion based on the procedure: collect information –
Ngày tải lên: 15/04/2017, 21:05
Analysis of microstructural effects on mechanical properties of copper alloys 2017 Journal of Science Advanced Materials and Devices
... rolling and recrystallization were analyzed by electron backscatter diffraction analysis (EBSD) [12] The evaluation of grain boundaries in copper bicrystals during one-Fig 1 Maximum rolling rates ... casting process, the solidification rate was varied Microstructural characteristics, as examined by electron backscatter diffraction analysis, were found to differ among the alloys Complicated microstructures ... considered to be due to increased dislocation density, while the low MO angles for the HF samples result from a reduction in internal stress due to the high-temperature processing In addition,
Ngày tải lên: 14/12/2017, 20:13
Effects of dietary protein and water exchange on water quality, survival and growth of postlarvae and juvenile litopenaeus vannamei
... information ex-ists on the interaction of effects of water exchange and shrimp size, and on the interaction of effects of water exchange and shrimp dietary protein level This study was conducted ... Protein 15% Protein 20% Protein 26% Protein 35% Protein High Exchange 0 2 4 6 8 10 -1 ) 0 20 40 60 80 100 Time ( day ) -1 ) Figure 2 Effects of dietary protein on levels of total ammonia nitrogen ... Chester, Pennsylvania, USA h Evonik, Brampton, Ontario, Canada a MP Biomedicals, Solon, Ohio, USA b Zeigler Brothers, Gardners, Pennsylvania, USA c Omega Protein, Houston, Texas, USA d TICA-alginate
Ngày tải lên: 27/09/2019, 10:20
Oleanane hemiacetal glycosides from Gymnema latifolium and their inhibitory effects on protein tyrosine phosphatase 1B
... tertiary carbons (nine oxygenated methines, one ole-finic carbon at δC125.0), eight secondary carbons (one oxygenated methylene at δC68.6) and ten methyl carbons (Table 2) Comparing its resonances ... moieties (Fig 3) Coupling constants and NOESY correlations confirmed the β configurations for H-2′ and 4′, and α orientations for H-1′, 3′, 5′, 1″, 3″ and 5′′ The 3J coupling constant (J = 10.0 Hz) ... C-1A−22(δC170.8) confirmed the acylated linkage positions at C-16, 21 and 22 The connection of the β glucuronic acid to C-3 was de-termined by the coupling constant J = 7.5 Hz of the anomeric proton, the
Ngày tải lên: 13/07/2020, 11:29
Collapsin response mediator protein 4 isoforms (CRMP4a and CRMP4b) have opposite effects on cell proliferation, migration, and invasion in gastric cancer
... proliferation, cell cycle progression, apoptosis, migration, invasion, and adhesion were determined by cell proliferation assays, flow cytometry analysis, transwell migration and invasion assays, ... opposite effects on cell proliferation, migration, and invasion in gastric cancer Keywords: Collapsin response mediator protein 4, Gastric cancer, Opposite effects, Stable cells * Correspondence: ... migrprolifer-ation, invasion, and adhesion We found that CRMP4a overexpression and CRMP4b silencing suppressed gastric carcinoma cell proliferation, migration, cell cycle progression, invasion, and adhesion,
Ngày tải lên: 20/09/2020, 15:06
ANALYSIS THE EFFECTS OF FERROELECTRIC ELECTRIC FIELD ON CURRENT-VOLTAGE CHARACTERISTICS OF THE FERROELECTRIC FIELD EFFECT TRANSISTOR USING SRBI2TA2O9 THIN FILM
... The effects of doping concentration The dependence of silicon doping concentration (Nsub) on the Ids is represented in equation (12) It is shown that the doping concentration effects to the conductivity ... charge of the ferroelectric on per unit area consists of linear polarization and nonlinear polarization component because of its ferroelectric effects QFe = nonlin+ lin = nonlin+ or . (1) Trang ... with silicon electronics, where the polarization state was read out by a device based on a field effect transistor configuration (MFIS) and a good process for FeFET having long data retention [6-8]
Ngày tải lên: 11/01/2021, 04:43
Effect of heat treament on food protein
... 10the water content of protein–lipid mixtures decreases The strong dependence of this losson the nature of the protein and on reaction conditions is obvious Reaction under alkaline condition Losses ... dependent on pH and on salt concentration Protein solubility is decreased (“salting-out” effect) at higher salt concentrations due to the ion hydration tendency of the salts Since proteins are ... thermal or enzymatic reactions in production, processing, and storage of food Other food constituents, e.g., carbohydrates, take part in such reactions Proteins also contribute significantly to
Ngày tải lên: 14/04/2021, 14:06
Research on hydrothermal carbonization (htc) of paper mill sludge, food and forestry wastes effects of process parameters on properties of hydrochar
... preparation Ammonium molybdate-antimony potassium tartrate solution, Ascorbic acid solution, Sulfuric acid, 11 N solution Ammonium molybdate-antimony potassium tartrate solution: Dissolve 8g of ammonium ... carbonization This trend is attributed to the formation of secondary char, which facilitates the conversion of dissolved carbon back into solid form Conversely, increased temperatures and longer ... of reaction time on these aromatization reactions (Basso, 2016).Other mechanisms occurring during the hydrothermal carbonization can be summarized as: During the Demethylation reaction, the phenol
Ngày tải lên: 12/12/2021, 21:02
Moreover, it is undeniable that the economic effects in which Superstars has left are tremendously apparent through these charts'' analysis below based on the MGI repor
... iisNevrhls,mon e2 uis ot ftegoeuesa iis hvmad pmor a 0% wit efu igs:hnhiHon Kon,igpr,n Seznawela te reprssc sHambugadBusn utemor,h p2 lretiprsaeciflyrm sprtrcte.o eeraos vdn a ee5 ctspa ioaoei oncigteeoomicatvts ... Trang 1RMI T I t r na t o na l Un i e s t Vi e nm ECON 19 Bu s ne s St a i t c S UPERS TARS 2 S ub j c Co de : ECON 19 S ub j c Na me : Bu s ne s St a i t c Lo ctn & Ca mp us ... eMGIeot 2 MGI e po r ’ nl s s Trang 3Ia eidctdfom tefirtrp ah 0cte xsigo emapaekowns“Suprtrcte"amon e30 igs ie ewordMeawhi,h iiescme fom te30 retiiscnrbt 7% iGDP awela 0% i eppltno e wor,h hbtnswhooiiaefom
Ngày tải lên: 09/05/2022, 20:33
ANALYSIS THE EFFECTS OF FERROELECTRIC ELECTRIC FIELD ON CURRENT VOLTAGE CHARACTERISTICS OF THE FERROELECTRIC FIELD EFFECT TRANSISTOR USING SRBI2TA2O9 THIN FILM
... The effects of doping concentration The dependence of silicon doping concentration (Nsub) on the Ids is represented in equation (12) It is shown that the doping concentration effects to the conductivity ... charge of the ferroelectric on per unit area consists of linear polarization and nonlinear polarization component because of its ferroelectric effects QFe = nonlin+ lin = nonlin+ or . (1) Trang ... with silicon electronics, where the polarization state was read out by a device based on a field effect transistor configuration (MFIS) and a good process for FeFET having long data retention [6-8]
Ngày tải lên: 25/10/2022, 12:23
Analysis of anthropogenic effects on topsoil throughout the Calif
... to demonstrate the effects of short-term and long-term trekking Researchers also investigated the influence of soil Trang 9compaction on microbial activity The study reveals that vegetation was ... clays This might have to do with construction of paths and the deliberate deposition of sand, or with the unintentional deposition of sand by walking and riding on pathways Texture differences ... they come in contact It is important that this relationship is monitored closely in any future studies This is especially necessary in areas where land preservation and soil conservation is vital
Ngày tải lên: 01/11/2022, 23:21
manager specific effects on earnings guidance an analysis of top executive turnovers
... evidence of a reduction in precision among newlyappointed CEOs, but find consistent evidence of a reduction in preci-sion among newly appointed CFOs This reduction is concentrated amongCFOs who are ... infrequent guider and nonguider samples (by construction) with 38%(50%) of observations issuing guidance in the next two (four) quartersamong infrequent guiders and only 9% (14%) among nonguiders Theseresults ... firms.We conduct our tests using only post-Regulation Fair Disclosure quarter observations (2001 through 2008) to establish a more homoge-neous institutional environment, but include observations prior
Ngày tải lên: 02/11/2022, 14:27
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