... Overlay of A and B (1 optic section) D GFP-ATM1(IQ-tail) (dots of 630 ± 60 nm) E FYVE-DsRED F Overlay of D and E (1 optic section) G RFP-ATM1(IQ-tail) (dots of 300 ± 100, colored green for ease of ... (Figure 1B) Because of the lack of good anti ATM1 antibodies in our hands, no com-parison to endogenous protein's level of expression was done Confocal-microscope images of roots of the trans-genic ... for ease of demonstration) I Overlay of G and H (1 optic section) J RFP-ATM1(IQ-tail) (dots of 570 ± 75 nm, colored green for ease of demonstration) K ARA6-GFP (colored magenta for ease of demonstration)
Ngày tải lên: 12/08/2014, 05:20
... and µMT mice following immunization (B) Expansion of LECs population in WT and µMT mice following immunization (C) Immunofluorescence analysis of WT and µMT LN sections (D and E) Expansion of ... marker of lymphatic transport and flow LV transport of FITC- dextran to LN following ‘LV resection’ was cut off compared to the ‘sham’ LN (B) At sacrifice, FITC-dextran injected into footpads of ... governed distribution of VEGF-A into the paracortex and medulla To further support this, disruption of interstitial flow was noted to obliterate association of VEGF-A with cortical and medullary sinuses
Ngày tải lên: 09/09/2015, 18:48
Mechanisms and functions of lymphangiogenesis in regulating the immune response and inflammation resolution 1
... 1MECHANISMS AND FUNCTIONS OF LYMPHANGIOGENESIS IN REGULATING THE IMMUNE RESPONSE AND INFLAMMATION RESOLUTION TAN KAR WAI (B.Sc (Pharm), NUS) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... being different and yet the same Trang 3Table of Contents ACKNOWLEDGEMENTS i TABLE OF CONTENTS ii ABSTRACT ix PUBLICATIONS xi LIST OF TABLES xii LIST OF FIGURES xii LIST OF ABBREVIATIONS ... 2.8 Culture of hybridoma cells and purification of antibodies… 39 2.9 Treatment of mice with antibodies and FTY720… 40 2.10 Dendritic cell migration assay ……… 41 2.11 Disruption of lymphatic
Ngày tải lên: 09/09/2015, 18:48
Expression pattern and functions of dihydropyrimindase like 3 in the rodent microglia
... 1EXPRESSION PATTERN AND FUNCTIONS OF DIHYDROPYRIMIDINASE LIKE-3 IN THE RODENT MICROGLIA JANANI MANIVANNAN NATIONAL UNIVERSITY OF SINGAPORE 2013 Trang 2 EXPRESSION PATTERN AND FUNCTIONS OF DIHYDROPYRIMIDINASE ... phagocytosis and proliferation of microglia 68 3.5.1 Knockdown of Dpysl3 alters the structure of F-actin organization 68 3.5.2 Knockdown of Dpysl3 inhibits migration of microglia 69 3.5.3 Knockdown of ... microglia altered the expression of proinflammatory cytokines such as TNF-α and IL-1β and inflammatory mediators including iNOS and NO and the migratory and phagocytic ability of activated microglia,
Ngày tải lên: 12/09/2015, 11:24
Regulation of subcellular localization and functions of RGK proteins by 14 3 3 and calmodulin
... 1REGULATION OF SUBCELLULAR LOCALIZATION AND FUNCTIONS OF RGK PROTEINS BY 14-3-3 AND CALMODULIN RAMASUBBU NARAYANAN MAHALAKSHMI DEPARTMENT OF PHYSIOLOGY NATIONAL UNIVERSITY OF SINGAPORE INSTITUTE OF ... identified and most of them possess a helix-loop-helix motif of about 30 amino acids which is called EF- hand motif Calmodulin belongs to the EF hand group of proteins and contains four EF hand motifs, ... the phosphorylated residues of the ligand fits in and this causes a conformational change in the ligand in most number of cases Based on the ligand bound, the functions of 14-3-3 proteins may differ;
Ngày tải lên: 14/09/2015, 18:28
Investigations on the tissue distribution, localization and functions of brain enriched leucine rich repeats (LRR) containing proteins AMIGO AND ngr2
... diverse functions and cellular locations (Kobe and Deisenhofer, 1994; Buchanan and Gay 1996; Kajava, 1998; Kobe and Kajava, 2001) The LRRs are generally 20-29 amino acids in length, and contain ... al., 2001) and one of its cognate ligand, the oligodendrocyte myelin glycoprotein (OMgp) (Vourc'h and Andres, 2004) These form an inhibitory axis of signaling that underlies inhibition of axonal ... AMIGO and examined the expression and localization of AMIGO in brain sections at the cellular level In order to gain a better understanding of functional domains of AMIGO, we generated AMIGO-LRR and
Ngày tải lên: 08/11/2015, 17:08
Classification, clinical features, and diagnosis of inguinal and femoral hernias in adults
... versions of this topic review Use of UpToDate is subject to the Subscription and License Agreement te of Diabetes and Digestive and Kidney Diseases; Washington, DC: US Government Printing Office, ... adults" and "Open surgical repair of inguinal and femoral hernia inadults" and "Laparoscopic inguinal and femoral hernia repair in adults".) Inguinal hernias in children and abdominal ... with thinning of skin and weakening of the soft tissues that may predispose to hernia development Other factors that affect the integrity of connective tissue include older age[5,12] and smoking
Ngày tải lên: 01/02/2018, 07:42
TECHNICAL FEATURES AND APPLICATIONS OF FMS TOOL, FMI TOOL, DSI TOOL FOR a 1x WELL, BLACK LION FIELD, CUU LONG BASIN
... design elements of the FMI are the pad and flap and electrode array Pad and flap are both conductive and have inset, 24 individually insulatedbutton electrodes, arranged in two rows of 12 Individual ... thickness of sand beds in a sand/shale turbidity sequence, down to 5 cm accurately For sand bedsthinner than this, interpretation of the electrical image gave an exaggeratedthickness and a corresponding ... Comparison of real thin bed thinness from core and estimated bed thickness from electrical images Sands were relatively more resistive than shale. Some notion of the practical possibilities of log
Ngày tải lên: 17/07/2018, 23:10
Summary of doctoral dissertation: The clinical, laboratorial features and treatment of spontaneous bacterial peritonitis in cirrhosis
... 1MINISTRY OF EDUCATION AND TRAINING DEPARTMENT OF DEFENSE THE CLINICAL RESEARCH INSTITUTE OF MEDICINE SCIENCE 108 - - VU THANH TRUNG THE CLINICAL, LABORATORIAL FEATURES AND TREATMENT OF SPONTANEOUS ... rupture of appendicitis, necrotizing cholecystitis, perforation of large intestine - Cases of tuberculosis or HIV - The cases of spontaneous peritonitis caused by fungus (results of culture of fungal ... results of antibiotic culture and antibiotic) Evaluate the clinical symptoms and re-test the hematological and biochemical parameters after 3 days of treatment Evaluation after antibiotic culture and
Ngày tải lên: 08/01/2020, 16:33
Starting from scratch: Prevalence, methods, and functions of non-suicidal self-injury among refugee minors in Belgium
... acts of NSSI Results of the SDQ’s Total Difficulties Scale and, more specifically, of the Emotional Prob-lems, Conduct ProbProb-lems, Peer Problems and Impact Scales indicate a substantial risk of ... Ilse.Derluyn@UGent.be 3 Faculty of Psychology and Educational Sciences, Department of Social Work and Social Pedagogy, Centre for the Social Study of Migration and Refugees, Universiteit Gent, ... prevalence An average of 2.65 methods of NSSI was applied (SD = 2.50; range 1–9) The mean number of functions per person was six (SD = 4.97, range 0–16), with auto-matic functions reported the
Ngày tải lên: 10/01/2020, 14:13
E2-EPF UCP regulates stability and functions of missense mutant pVHL via ubiquitin mediated proteolysis
... and then, HIF-2α and its targets were analyzed at the protein and mRNA levels Missense mutant pVHL decreased the protein levels of HIF-2α and cyclin D1 (Fig 5a) and the mRNA levels of Glut1 and ... at 4 °C The total reaction volume was 50μl and contained 50μg of 786-O cell extracts, 3 μg of GST-ODD, 0.3 μg of His-VHL, 0.3μg of UBCH5C, and 0.5 μg of His-E1 in reaction buffer The mixtures ... pur-chased from SLC japan and maintained in a accordance with guidelines and approval of Institutional Review Committees for Animal Care and Use, Korea Research Institute of Bioscience and Biotechnology
Ngày tải lên: 23/09/2020, 00:04
STRUCTURES AND FUNCTIONS OF COMMISSIVES BY US PRESIDENTS
... acts and relevant issues in the genre of politicaldiscourse The results of this study are expected to help Vietnameselearners of English improve their understanding of structures andfunctions of ... withdefining functions were examined in clause as message and clause ofmaterial The study looked into issues of semantics like the semanticfunctions of the components of an act of defining It ... reveals the overview of the study including the statement ofthe problem, research aim and objectives, research questions, scope of thestudy, significance of the study, and structure of the thesis -
Ngày tải lên: 21/11/2021, 12:02
Nature and functions of urbplg slides
... 1Nature and Functions of Urban Planning Songsu Choi Lead Urban Economist and China Urban Sector Coordinator The World Bank Module 1: Nature and Functions of Urban Planning Trang 2n Types and Functions ... details of Output, Input and Schedule • Goals and End Vision – Drawings and Models • Difficult in large and changing contexts Trang 4Type of Planning II: Strategy n Plan of Action; Rules and Directions ... (sectoral synthesis) • Locate and allocate land to various of activities and structures (Land Use & Infrastructure Plans) • Set standards and rules (zoning) for various land use Ø to maximize
Ngày tải lên: 10/06/2022, 11:16
Đặc điểm hình thái – động lực và phân bố vũng vịnh ven bờ biển việt nam – morpho dynamic features and distribution of bays along the coast of vietnam
... động lực và phân bố vũng -vịnh ven bờ biển Việt Nam Morpho - dynamic features and distribution of bays along the coast of Vietnam Nguyễn Hữu Cử, Nguyễn Đình Hồng Giá trị về an ninh, quốc phòng ... địa chất môi trường vùng bờ biến Việt Nam và giải pháp ứng xử Problems of environmental geology of the Vietnam coastal areas and adjustable measures Bùi Văn Vượng, Trần Đức Thạnh, Nguyễn Hữu Củ, ... của hệ thống vũng vịnh ven bờ biến Việt Nam Values on the national security and defence of bays a long the coast of Vietnam Trang 15 25 5S Trang 3Tạp chí Khoa học và Công nghệ biển, Phụ trương
Ngày tải lên: 14/10/2022, 11:38
Biosynthesis and functions of sulfur modifications in tRNA
... (Urm1 and Tum1), and an activation enzyme for Urm1 (Uba4; Figure 3B) The gene names here are those of S cerevisiae, and homologs of Ncs6/Ncs2 and Uba4 in humans are designated ATPBD3/CTU2 and MOCS3 ... (University of Tokyo) and Dr Hiro-fumi Nakagawa (University of Tokyo and RIKEN) This study was supported in part by KAKENHI Grant (24570173) of the Ministry of Education, Culture, Sports, Science, and ... TtuA and Ncs6 belong to group II of the TtcA family TtuA is composed of two Zn finger domains and a catalytic domain TtcA is responsible for the formation of 2-thiocytidine34 (B) Structure of P
Ngày tải lên: 19/11/2022, 11:45
Dissection of genomic features and variations of three pathotypes of puccinia striiformis through whole genome sequencing
... FGENESH and MapRep of MolQuest2.2 software package for the prediction of genes and TEs, respectively Predicted genes were self-BLAST searched and parsed to remove dupli-cates and partial and redundant ... events of genetic recombination by ‘Difference of Sum of Squares’ (DSS) method (McGuire and Wright, 2000)39 with window size of 500 and Jukes-Cantor model of nucleotide substitution Prediction of ... with the Tandem Repeats Finder 4 software with default parameters36 (https://tandem.bu.edu/trf/trf.html) The SSR identification was done in all three genomes using MISA software and categorized
Ngày tải lên: 24/11/2022, 17:41
Báo cáo khoa học: Structural features and dynamics of a cold-adapted alkaline phosphatase studied by EPR spectroscopy docx
... 10 )10 and )1.36, respectively [48]. Acknowledgements The authors would like to thank the University of Ice- land Research Fund and the Icelandic Research Fund for financial support; Professor ... the Institute of Biology, University of Iceland, for access to DNA sequencing; Pavol Cekan for help with EPR measurements; and Professor Leslie Fung at the Chem- istry Department, University of Chicago ... and dynamical features of a cold-adapted AP using site-directed spin-labeling in conjunction with EPR spectroscopy. The effects of cysteine mutations and spin-labeling on kinetic properties and...
Ngày tải lên: 16/03/2014, 01:20
The Practices and Functions of Customer Reference Marketing − Leveraging Customer References as Marketing Assets pptx
... Wernerfelt, 1984; Grant, 1991), and particularly to the customer-based view of strategy and firm growth (Zander and Zander, 2005), in terms of addressing the multifaceted nature of customer references ... pay more attention to the role and importance of customer relationships, and to examine them as a source of competitive advantage and firm growth (Zander and Zander, 2005). Moreover, further ... for customer-need and market sensing supports the customer-based view of strategy and firm growth (Zander and Zander, 2005) and could be compared with Penrose’s (1959) notion of an ‘inside track’,...
Ngày tải lên: 23/03/2014, 03:20
A new approach to semantic and syntactic functions of English adjectives – A contrastive analysis with their Vietnamese equivalents
... overview of English adjectives with the definitions of adjectives and their semantic and syntactic functions of English adjectives. Chapter III is a study to a new approach to semantic and syntactic ... semantic and syntactic functions of adjs. The writer discusses their classification according to their usage then considers them if which kinds of adjective belong to semantic functions and syntactic ... adjectives as type 1, type2, typr3 and type 5, and as for dynamic ones like type7, 9 and type 10. And then, the kinds of adjective belonging to syntactic functions are also classified clearly...
Ngày tải lên: 10/04/2013, 14:46
Tài liệu Báo cáo khoa học: Branched N-glycans regulate the biological functions of integrins and cadherins doc
... the upregulation of GnT-III. In fact, the results of several studies suggest that E-cadherin can induce ligand-independent activation of EGFR and subse- quent activation of Rac1 and MAP kinase, ... and evidence for gain- and loss- of -functions of target proteins for glycosyltransferases involved in N-glycan biosynthesis: their pivotal roles in growth and development, cancer metastasis and ... modifi- cation of particular sites, which are involved in regula- tion of the conformation of integrin, determine the extent of cell migration. The mutual regulation of GnT-III and E-cadherin To...
Ngày tải lên: 18/02/2014, 17:20
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