disorders of platelets and coagulation

... Trang 1Disorders of Diverticulation and Cleavage Sulcation and Cellular Migration Disorders of Diverticulation and Cleavage: Holoprosencephalies and Related Disorders AND RELATED DISORDERS ... (polymicrogyria) and relative paucity of underlying white matter (Figs 3-14 and 3-15) to more focal areas of thickened, flattened cortex (pachygyria) (Figs 3-16 and 3-17) Approximately one quarter of patients ... in a spectrum of brain malformations.10 These are divided into several types, depending on the timing and severity of the arrest of neuronal migration.2 Lissfincephaly Etiology and pathology

Ngày tải lên: 29/12/2020, 17:06

... 1Nonneoplastic Disorders of the Spine and Spinal Cord Infection Spondylitis and Diskitis Epidural and Subdural Infections Meningitis, Myelitis, and Cord Abscess Normal Aging and Disk Degeneration ... Soft Tissue Injuries In this chapter we consider benign acquired disorders of the spine and spinal cord, beginning with infection and demyelinating diseases and INFECTION Spondylitis and ... Degeneration or bulging of at least one lumbar disk is seen in 35% of patients between 20 and 39 years of age and in virtually all patients over 60 years of age.56 Vertebral body and marrow space changes

Ngày tải lên: 29/12/2020, 17:07

... Alcohol dependence affects 4% of people aged between 16 and 65 in England (6% of men and2% of women), and over 24% of the English population (33% of men and 16% of women) consume alcohol in a ... activity anddomestic violence, and an increased rate of significant mental and physical disorders Althoughalcohol dependence is defined in ICD-10 and DSM-IV in categorical terms for diagnostic andstatistical ... dependence and seeking help, and the limited availability of specialist alcoholtreatment services in some parts of England Additionally, alcohol misuse is under-identified byhealth and social care professionals,

Ngày tải lên: 21/02/2014, 11:20

... activation of scu-PA and plasminogen constitutes a mechanism of localized initiation and propagation of pericellular proteolysis [63–66] and fibri-nolysis on platelets [67] The mechanism of the initiation ... structure of each component of the systems, and modulation of the programmed function of the component can provide a novel means of pharmacological intervention in dis-eases associated with the coagulation ... Detailed anal-yses of the action of such modulators have expanded the concept of zymogen modulation, leading to the identification of additional modulators that affect the coagulation system The

Ngày tải lên: 06/03/2014, 22:21

... evaluation, and management of the hypertensive disorders of pregnancy The resulting guidelines, published in the CMAJ in 19974–6 and endorsed by the Society of Obstetricians and Gynaecologists of Canada, ... Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy Table 2 Classification of the hypertensive disorders of pregnancy* Primary diagnosis Definition of preeclampsia† Pre-existing ... Hypertensive Disorders of Pregnancy Trang 9INTRODUCTION The hypertensive disorders of pregnancy are a leading cause of maternal and perinatal mortality and morbidity in Canada1 and internationally.2,3

Ngày tải lên: 28/03/2014, 14:20

... diseases, namely foot-and-mouth disease, bluetongue, and bovine spongiform encephalopathy (BSE) The advice on management of many diseases and disorders has been revised and expanded, as have the ... Asia, Europe and Australasia illus-Wherever possible, we have tried to illustrate characteristic features of disorders This has involved the use of a substantial number of internal views of animals ... of its potentially enormous value to veterinary medicine I congratulate Wolfe and the authors on their courage and perseverance in going ahead and getting it done Professor Emeritus, School of Veterinary Science, University of Melbourne

Ngày tải lên: 28/03/2014, 22:21

... patients suffering from disorders and diseases of the brain, the advances in brain research provide hope in the form of their own understanding of what is going wrong and in the form of advances in novel ... environmental factors, and eruption of neuropsychiatric disorders We have provided an overview of the unique properties and connectivity of the PFC circuitry and alterations during the juvenile and adolescent ... Syndromes and Disorders Trang 151 The Unique Properties of the Prefrontal Cortex and Mental Illness Wen-Jun Gao*, Huai-Xing Wang, Melissa A Snyder and Yan-Chun Li Department of Neurobiology and

Ngày tải lên: 28/06/2014, 11:20

... University of Bern, and Chief of Staff, Department of Orthopaedic Surgery, Hirslanden-Salem Hospital, Bern, Switzerland Max Aebi is Co-Founder and Past Chairman of AO Spine, a member of the European ... in 1960 and is a Swiss citizen He studied at the University of Saarland, Germany, and the University of Basle, Switzerland He then received an international training as an orthopedic and spinal ... General and Orthopedic Surgeon (FMH and FRCSC), and did his spine fellowship training in Canada, the United States and the United Kingdom From 1992 to 2002, he held the positions of Professor and

Ngày tải lên: 02/07/2014, 06:20

... (Editors)Spinal Disorders Fundamentals of Diagnosis and Treatment Trang 3Norbert Boos · Max Aebi (Editors)Spinal Disorders Fundamentals of Diagnosis and Treatment With 274 Figures in 1290 Parts and 190 ... knowledge and general princi-ples of spinal disorders The didactic concept (form) of all the chapters is based on a consistent style and layout, and follows three basic principles of sustainable ... difficult choices in the allocation of treatment modalities Therefore, a basic knowledge of the state of the art of the diagnosis and treatment of spinal disorders is required, not only for spine

Ngày tải lên: 02/07/2014, 06:20

... Spinal Disorders 154 Classification of Spinal Disorders 155 Etiology 155 Time Course 155 Low Back Pain 156 Neck Pain 157 Pain, Impairment and Disability 157 Burden of Spinal Disorders ... Outcome of Common Spine SurgicalProcedures 182 Predictors of Outcome of Spinal Surgery 183 Medical Factors 184 Biological and Demographic Variables 186 Health Behavioral and Lifestyle ... Diagnosis 306 Differentiation of Central and Peripheral Paresis 306 Differentiation of Radicular and Peripheral Nerve Lesions 306 Differential Diagnosis of Spinal Cord Compression Syndromes

Ngày tải lên: 02/07/2014, 06:20

... vertebra of his neck, penetrating to the bone, (and) perforating a vertebra of his neck; if thou examinest that wound, (and) he shudders exceedingly, (and) he is unable to look at his two shoulders and ... father of anatomy, and later Galen of Pergamon (130–200 A.D.) made the first observations on the nervous system and the spine. Galen identified the number of vertebrae in each segment of the ... clinical and pathological practice, the cellular contents of the gray matter were identified, and since then there have been steady advances in our understanding of the spinal cord. Anesthesia and

Ngày tải lên: 02/07/2014, 06:20

... patients and the method was abandoned. It may be of interest that the contro- versy over this technique was one of the first incidences of doctors criticizing and attackingeachotherinprintandincourt. ... concept of spinal derotation devices[22].Bymeansofthissystem,itwaspossiblenotonlytoaddresslateral deviation of the spine but also apical rotation and thereby improve the sagittal profile of the ... discovery of aqueductus of the inner ear and his description of the typhoid ulcers. It was finally the English physician Brown of Glasgow in 1828 who first suggested that irritation of the ner-

Ngày tải lên: 02/07/2014, 06:20

... injuries which lead to handicap and disability In the past, most of the patients with spinal cord injuries died after a short time because of a combination of pressure sores and urinary tract infection ... described the association of paraple-gia and kyphotic deformity Dalechamps still believed in the method of mechanical treatment of a “spina luxata” by performing extension and simultaneously sitting ... a great American orthopedic surgeon at the beginning of the 20th century and co-founder of the International Society of Orthopaedic Surgery and Traumatology (SICOT), first reported on a successful

Ngày tải lên: 02/07/2014, 06:20

... (1877) A case of simple synostosis of the ribs to the vertebrae, and of the arches and the articular processes of the vertebrae themselves, and also of one hip-joint Transac-tions of the Pathological ... lumbar and sacral The cervical and lumbar spine are of greatest interest clinically, due to the substantial loading and mobility of these regions and associated high inci-dence of trauma and degeneration ... buckling of a slender column is proportional to the cross-sectional area of the column and the stiffness of the material and inversely proportional to the square of the unsupported length of the

Ngày tải lên: 02/07/2014, 06:20

... between 3° and 12° rotation there is a linear relationship between torque and rotation and failure of the anu-lus fibers occurs at a rotation of more than 20° rotation Measurements of inter-nal ... joints guide and limit intersegmental motion The posterior elements guide the motion of the spinal segments and limit the extent of torsion and anterior-posterior shear The transverse and spinous ... together, and con-sists of the ligamentum flavum, facet capsule, and interspinous and intertrans-verse ligaments The intersegmental system holds many vertebrae together and includes the anterior and

Ngày tải lên: 02/07/2014, 06:20

... this refer- enceandteachingtextreviewsandanalyzestheclinicalandscientificdataonthe mechanics of the human spine. The text covers all aspects of the physical and functional properties of the spine, ... alteration of the motion patterns of the spine. Changes to the instant center of rotation may have consequences for the loading of peripheral structures of the spine. As determined from in vitro and ... force exerted by the weight of the object and the force produced by the erector spinae muscles. The upper body weight and the weight of the object act in front of the disc and therefore create forward

Ngày tải lên: 02/07/2014, 06:20

... – 410 51 Mayer TG, Tencer AF, Kristoferson S, Mooney V (1984) Use of noninvasive techniques for quantification of spinal range-of-motion in normal subjects and chronic low-back dysfunc-tion ... 66 Oxland TR, Panjabi MM (1992) The onset and progression of spinal injury: a demonstration of neutral zone sensitivity J Biomech 25:1165 – 1172 67 Panjabi MM (1992) The stabilizing system of the ... between radiographic and clinical measurement of lumbar spine movement Br J Rheumatol 22:197 – 205 77 Ranu HS (1990) Measurement of pressures in the nucleus and within the anulus of the human spinal

Ngày tải lên: 02/07/2014, 06:20

... instrumentation.The aims of spinal instrumentation are stabilization, achievement and maintenance of curve correction (alignment) and facilitation of bony fusion (spondylodesis) Knowl-edge of the underlying ... flexion and lateral bending, interbody devices can restore stability profoundly However, the major disadvantage of these devices regardless of the approach (PLIF or ALIF) is the poor control of extension ... of anterior tension band instrumen-tation and a cage is a promising up-and-coming technique A potential alternative to the above-mentioned combined instrumentation is the recent development of

Ngày tải lên: 02/07/2014, 06:20

... changes of the disc ✔ Orientation and misalignment of the facet joints correlate with development of early osteoarthritis of the joint ✔ Changes in bone architecture of the vertebral bodies and formation ... function increases proba- bility and severity of soft tissue and skeletal damage due to trauma and also enhances the likelihood of complications during surgery. The number of people over 65 years will ... spine and osteoarthritis of the synovial joints coexist and in most cases are interrelated [145]. Autopsy studies by Schmorl and Junghanns [64] reported evidence of spondylosis in 60% of women and

Ngày tải lên: 02/07/2014, 06:20

... very similar and consist of: water proteoglycans collagen Wate r makes up 80% of the wet weight of the nucleus and 70% of the wet weight of the anulus [105, 162]. Collagen and proteoglycans fulfil ... pulposus and with- standing the resulting tensile forces consists of up to 70% (percent dry weight) of collagentypeIandIIwhereasthenucleuspulposusonlycontains20%ofcolla- gen [31]. On the other hand, ... intersperse the lamellae and may play an important role in restoration of shape after bending of the spine [161]. The cellular part of theanulusfibrosusconsistsofthinandelongatedfibroblast-like

Ngày tải lên: 02/07/2014, 06:20