carcinogenesis malignant transformation and progression

... centered at s, s1, e and their radii equal the distances between s and p1, s1 and p1 (or p2), and e and p2, respectively The only data points that can be closer to se (than p1 and p2) must fall ... parties A and B hold objects a and b, respectively They want to compute a function f (a, b) with- out A learning anything about B and vice versa They encrypt their objects using random keys and follow ... and K to the anonymizer, which removes the id of the user and forms his location through cloaking The generated K -ASR is forwarded to trans-the LBS which processes it and returns a set of candidates,

Ngày tải lên: 12/09/2015, 08:19

... guidance and for proofreading this manuscript; Honours students Soon Tuck, Hui Hui and Tze Chin, for their contributions in the Cav-1 work; Dr Liu, Guo Hua and Hong Heng for their advice and support ... for your friendship and camaraderie, and for making my stay in the lab truly enjoyable To all staff and students of the Department of Physiology, NUS, for the advice, support and friendship Special ... vitro and in vivo assays, as well as genetic profiling using the microarray technique HDAC1 and HDAC2 are two isoforms of the Class I histone deacetylases In this study, HDAC1 and HDAC2 mRNA and

Ngày tải lên: 07/10/2015, 10:02

... ρ, υa, and ξ are the volume, the crystal density, the acoustic wave velocity, and the deformation potential constant, respectively ε0 is the electronic constant; χ0 and χ∞ are the static and high ... equations for the Fourier transformations Bm,−→q ⊥(ω) and Cm,−→q ⊥(ω) of D bm,−→q ⊥ E t and Dcm,−→q ⊥ E t, respectively For instance, the equations for Bm,−→q ⊥(ω) and Cm,−→q ⊥(ω), can be written ... relations for confined acoustic and confined optical phonons as ωac(m, −→q⊥) = ωa+ iτa and νoc(m, −→q⊥) = ω0+ iτ0 with conditions |ωa|  |τa| and |ω0|  |τ0|, and consider the case of N = 1,

Ngày tải lên: 30/10/2015, 19:51

... 1Sorption, Transformation and Transport of Sulfadiazine in aloess and a sandy Soil Genehmigte Inaugural-Dissertation zurErlangung des Grades Doktor der Agrarwissenschaften (Dr agr.)derLandwirtschaftlichen ... non-linearity and kinetics Trang 191.2 General objectives and outline of the thesisThe overall objective of this thesis was to improve the standing of sorption, transformation and transport of ... Thetransformation in the batch experiments is analyzed in Chapter 3, by presenting new transformation processes in soils and ing with a compartment model description for the dissipation andtransformation

Ngày tải lên: 25/11/2015, 15:20

... availability of labor and land The expansion of human settlements, tourism, and agricultural activities into coastal zones of Thailand and Vietnam has had major effects on coastal land-use and infrastructure ... consumers demand convenience, are concerned with quality, want food that is varied and interesting, nutritious and healthy, and increasingly demand that it is produced in environ- mentally and socially ... Trang 1Royal Swedish Academy of SciencesIndustrial Transformation and Shrimp Aquaculture in Thailand and Vietnam: Pathways to Ecological, Social, and Economic Sustainability? Author(s): Louis Lebel,

Ngày tải lên: 16/12/2017, 01:27

... Processing 5Intensity transformation function s T r = ( ) II Intensity transformation function Functions Trang 4Digital Image Processing 7Trang 5Digital Image Processing 9Log Transformations log(1 ... inverse transformation from s back to r is r = T -1 (s) ; 0 ≤s ≤1 III.1 Histogram Equalization „ Let ‰ p r (r) denote the PDF of random variable r (r) ‰ p s (s) ) denote the PDF of random variable ... and T(r) are known and T(r) T-1(s) satisfies (s) condition (a) then ps(s) ) can be obtained using a formula : ds dr (r) p (s) ps = r Trang 14Digital Image Processing 27function (CDF) of random

Ngày tải lên: 01/04/2019, 10:40

... 4 and Table 3 that the vibration modes characterizing both anatase and rutile phases broaden and shift, when increasing Mn2+content For the anatase phase, the Eg(1) and Eg(2) modes broaden and ... locate in the band gap In this case, the electrons do not directly transit to the conduction band, but via the states in the band gap Hence, both the sub-band states of Mn2+ions and oxygen vacancy ... [F(R)hν]1/2 and [F(R)hν]2 versus photon energy hν are represented in Fig 5(c) and Fig 5(d) The band gap energies Egfor different Mn2+ -doped TiO2nanoparticles determined from Fig 5(c) and Fig 5(d)

Ngày tải lên: 13/01/2020, 12:58

... NAFLD and NASH ASK1 pathway plays a role in both inflammation and fibrosis of NAFLD and NASH [4, 49, 50] Materials and Methods Cell lines and reagents Human hepatoma cell lines (HepG2 and Huh7), ... NAFLD and NASH The number of patients with NAFLD and NAS has been increasing in the USA, Europe and Asian countries [3, 4] NAFLD and NASH can lead to advanced liver diseases including cirrhosis and ... obesity in men and regulates body mass, adiposity and energy expenditure, in the progression of NAFLD and NASH We performed knockdown of endogenous ARRDC3 in human hepatocytes and examined the

Ngày tải lên: 15/01/2020, 11:26

... progression in advanced CKD and old age [42–46] Blood Sugar control Blood sugar ; UAE;, incident CKD;, CKD progression ; Hypoglycemia increases morbidity and mortality risk esp with SU and insulin [47,48] ... predictor of increased risk of renal disease and mortality in T1DM[7] The predictive value of microalbuminuria for renal and cardiovascular disease morbidity and mortality was later con-firmed in T2DM ... dis-coveries in experimental and clinical trials, a new strategy of DN treatment should be implemented In this review, an updated approach to prevent, and control the progression of DN will be highlighted

Ngày tải lên: 15/01/2020, 13:16

... Performance Unequal land distribution – Large and powerful landowners – Sharecroppers, landless peasants, and farm workers Trang 13Wesley. All rights reserved 9­13 Agricultural Land Distribution ... money for buying seeds and fertilizer – Hold land as collateral – Take over the land in case of loan default in poor-crop years – Become landowners themselves Trang 20• Land and income disparity• ... land • Massive underemployment, but labor shortage in crop season Trang 22• Land and income disparity• Rapid population growth small farmers • Massive R-U migration • Rapid deforestation and

Ngày tải lên: 16/01/2020, 12:26

... precision of 2.7–5.8%, and an inter‐assay precision of 3.5–6.5% Tumor progression and CgA levels were assessed every 12 weeks during year 1 and every 24 weeks during year 2 Tumor progression was assessed ... (CgAt), (ii) CgA levels at baseline (CgA0), and (iii and iv) the difference and ratio between CgA levels at each time and CgA levels at baseline (CgAt− CgA0 and CgAt/CgA0, respectively) A Weibull ... LAN, CgA, and Tumor Progression Serum LAN was measured at (i) baseline; (ii) between thefirst and second administrations (weeks 1–4)—either, two blood samples taken at 4 h (range 2–12 h) and 7 days

Ngày tải lên: 11/05/2020, 11:43

... Lane Detection Algorithm Based on Top View Image Transformation and Least-Square Approaches Byambaa Dorj and Deok Jin Lee School of Mechanical and Automotive Engineering, Kunsan National University, ... lane-detecting and lane-keeping capability for advanced driver assistance systems This paper introduces an efficient and lane detection method designed based on top view image transformation ... these days In hostile road conditions, a recognition and detection capability of road signs, road lanes, and traffic lights is very important and plays a critical role for the ADAS systems [2,

Ngày tải lên: 06/07/2020, 01:56

... was associated with worse prognosis, and poorer outcomes after stand-ard chemotherapy in Egyptian patients with TNBC, and lymph node and distant metastasis, and therefore higher AJCC stage This ... DeWitt and Mrs Peggy Crawford (WeS), and National Cancer Institute, Egypt (AB) The funding bodies had no role in the design of the study and collection, analysis, and interpretation of data and ... period was 33 months Local recurrence and distant metastases were assessed; and disease-free survival (DFS) and over-all survival (OS) were calculated Pathology and immunohistochemistry Immunohistochemistry

Ngày tải lên: 06/08/2020, 07:48

... the progression towards gastric cancer during the course of Helicobacter infection. Methods: Wild type (WT) and Myd88 deficient mice (Myd88−/−) were infected with H felis for 25 and 47 weeks and ... to the development and progression towards gastric cancer are critical in deter-mination of cancer pathology H pylori-induced gastric carcinogenesis involves a multistep progression from normal ... 213 (Rnf213) and Furin, which have been re-ported to be involved in angiogenesis [37, 38] and cancer progression [39], respectively indicating their role in advanced stages of cancer progression.

Ngày tải lên: 20/09/2020, 01:26

... of SiO4, SiO5, and SiO6 units is very stable and not dependent on compression Here angle distribution in SiO4 units has a form of Gauss function and a pronounced peak at 105° and 90° with SiO5 ... non-bridging O atoms and it has a slight effect on the topology of SiOx and OSiy units Moreover, the diffusion of network- former atom in sodium-silicate melt is anomaly and diffusion coefficient ... network-former atoms and modifier atoms Keywords: Molecular dynamics, microstructural transformation, mechanism diffusion, sodium-silicate 1 Introduction The structural transformation in multi-component

Ngày tải lên: 27/09/2020, 17:46

... Baron B, et al Comparison of CA-125 and standard definitions of progression of ovarian cancer in the intergroup trial of cisplatin and paclitaxel versus cisplatin and cyclophosphamide J Clin Oncol ... serous EOC patients and patients with benign gynecological diseases The P value is indicated for each factor ROC analysis using leptin, suPAR and CCL18 (h), and IL-6, IL-10 and OPG (i) for distinguishing ... as Bcl-2 and IAPs, and downregulation of pro-apoptotic proteins, such as BID and BAX [34, 53] In this study however, we did not observed a correlation between IL-6 levels in ascites and clinical

Ngày tải lên: 28/09/2020, 09:59

... roles during cancer progression The aims of this study are to investigate the serum soluble N-cadherin (sN-CAD) levels in patients with malignant bone and soft tissue tumors, and to evaluate the ... Conclusions: sN-CAD is a biomarker for malignant bone and soft tissue tumors, and a potentially valuable pre-therapeutic prognostic factor in patients with bone and soft tissue sarcoma Keywords: Sarcoma, ... differentiation, cell shape and migration, which in turn influence the tissue morphogenesis and structure The signaling is also involved in pathogenic events such as carcinogenesis and distant metastasis

Ngày tải lên: 05/11/2020, 06:47

... 9q, 11q, 12q, 13q, 15q, 17 and 22q, and losses at 1p, 2q, 4, 9p, 10, 12q 13q, 14q, 16, 18q, 20q, and 21 [20] Of these aberrations, gains at 7p and 15q, and losses at 6q, and 18q were also detected ... MUC1, MUC2, and MUC5AC, but MUC6 and VEGF Staining with CD10 and CDX2, p53, and p16 was nega-tive, whereas p21 was only focally expressed Prolifera-tive activity was assessed by Ki67, and estimated ... gland ad-enoma as described previously [17] and revealed chro-mosomal gains at 7p, 7q11q21, 15q, 16p, 20, losses at 6p23pter, 6q, 18, and amplifications at 1q and 6p21p22 in the pyloric gland

Ngày tải lên: 05/11/2020, 07:57

... examination and follow-up to prevent the occurrence and progression of cervical lesions The predictive random forest models The random forest model consists of multiple decision trees, and there ... CIN were HPV infection and TCT-diagnosed CINII+, and the significantly upregulated genes were TGFBR2, FOXO1 and CTBP2 Logistic analysis of risk factors for CIN progression and occurrence To explore ... established for predicting the occurrence and progression of CIN (7 models for predicting CIN progression and 6 models for predicting CIN occur-rence) (Table 5and6) To avoid missing potential inde-pendent

Ngày tải lên: 05/11/2020, 08:17

... the current and past shape of the term structure Savings banks and cooperative banks are said to rely heavily on earnings from term transformation And, in fact, the earnings from term transformation ... risk, and the second one deals with the relationship of the interest margin and the possible earnings from term transformation Fraser et al (2002) for the U.S., Ballester et al (2009) for Spain and ... (t) are the earnings from term transformation of bank i and of the bond portfolio, respectively Combining (11) and (12), we see that a bank’s earnings from term transformation depend multiplicationally...

Ngày tải lên: 16/02/2014, 06:20