and biological activity of isothiocyanates and indoles

... the isolation and biological activity of natural active compounds from plants and endophytes" 2 Objectives and aims of the dissertation Trang 4The research object is 4 species of plants including ... temperature of 45 ° C, obtained 240 g of residue of methanol The residue of methanol is added with water and extracted with an increasing solvent of n-hexane and ethyl acetate After removal of the ... mushrooms of Piper betle • Compound 31: Trang 16 3.3 Screening test of insecticidal and fungal activity of extracts, fractions and clean substances The inhibit activity to Spodoptetra litura worm and

Ngày tải lên: 09/01/2020, 14:59

... OF EDUCATION & TRAINING VIET NAM ACADEMY OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY OF SCIENCE AND TECHNOLOGY - - NGO HANH THUONG SYNTHESIS AND IDENTIFICATION BIOLOGICAL ACTIVITY OF ... in National Library of Vietnam and the library of Graduate University of Science and Technology A INTRODUCTION TO THESIS Graduation, scientific and practical significance of thesis topic Indenoisoquinoline ... increase activity and some cases avoidance Drug resistance versus one component Thus, the synthesis of new derivatives and cytotoxic activity assays for the detection of antitoxin-active agents of

Ngày tải lên: 09/01/2020, 15:23

... objectives of the thesis Study on chemical constituents and biological activity of two species: B Laxiflora and F hirta 3 The main contents of the thesis Isolation and determination of chemical ... Evaluation of some biological activity of extracts and isolated compounds: anti-inflammatory activity, in vitro, apoptosis CHAPTER 1 OVERVIEW 1.1 Introduction of B laxiflora Hemsl 1.2 Introduction of ... 2016 and were identified by Assoc Prof Do Huu Thu, Institute of Ecology and Biological Resources, Vietnam Academy of Science and Technology (VAST) A voucher specimen has been kept in Laboratory of

Ngày tải lên: 10/01/2020, 06:40

... percentage of inhibitory activity was 61.91% at a dose of 200 mg/kg of the extract, whereas it was 75% at 150 mg/kg of aspirin Immunomodulatory activity Ethyl acetate and n-butanol extracts of P lanceolata ... dysentery, gonorrhea, syphilis and snake poisoning This article covers the period from 1962 to 2017 and presents an overview of the biological activity of different Biological activities Antiplasmodial ... medicinal and poisonous plants of southern and eastern Africa: being an account of their medicinal and other uses, chemical composition, pharmacological effects and toxicology in man and animal

Ngày tải lên: 14/01/2020, 17:02

... OF EDUCATION & TRAINING VIET NAM ACADEMY OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY OF SCIENCE AND TECHNOLOGY - - NGO HANH THUONG SYNTHESIS AND IDENTIFICATION BIOLOGICAL ACTIVITY OF ... in National Library of Vietnam and the library of Graduate University of Science and Technology A INTRODUCTION TO THESIS Graduation, scientific and practical significance of thesis topic Indenoisoquinoline ... increase activity and some cases avoidance Drug resistance versus one component Thus, the synthesis of new derivatives and cytotoxic activity assays for the detection of antitoxin-active agents of

Ngày tải lên: 15/01/2020, 10:33

... objectives of the thesis Study on chemical constituents and biological activity of two species: B Laxiflora and F hirta 3 The main contents of the thesis Isolation and determination of chemical ... Evaluation of some biological activity of extracts and isolated compounds: anti-inflammatory activity, in vitro, apoptosis CHAPTER 1 OVERVIEW 1.1 Introduction of B laxiflora Hemsl 1.2 Introduction of ... 2016 and were identified by Assoc Prof Do Huu Thu, Institute of Ecology and Biological Resources, Vietnam Academy of Science and Technology (VAST) A voucher specimen has been kept in Laboratory of

Ngày tải lên: 16/01/2020, 19:50

... reversible, and weak inhibitor binding Contrary to other NSAIDs that inhibit COX reversibly and rapidly (mefenamic acid and ibuprofen), or irreversibly and slowly (indomethacin and diclofenac), ... 166 ppm and the methythio-, methylsulfonyl- and phenoxyl-bearing carbon signals at 156.6, 161.3 and 167.1, respectively 1H NMR of 3 and 5 showed a char-acteristic singlet of methylthio and methylsulfonyl ... evaluating and assessing the degree of inflamma-tion and the therapeutic and curative effects of bioactive compounds The response of target compounds 1–20 ranged from weak to moderate activity,

Ngày tải lên: 29/05/2020, 12:32

... and evaluated against five fungi [21], and the results of bioas-say showed that compounds 8 and 9 (Fig. 1) could exhib-ited strong activity against P piricola with EC50 values of 3.00 μg/mL and ... water and diluted to a final concentra-tion of 200 μmol/L Rice plants at the four-leaf of the sim-ilar size were sprayed with a concentration of 200 μmol/L of test conjugate 5c, PCA and of salicylic ... hydroxybenzoic acid ester conjugates of phenazine-1-carboxylic acid and investigated their biological activity Most of the syn-thetic conjugates displayed some level of fungicidal activity in  vitro against

Ngày tải lên: 29/05/2020, 13:21

... IR spectra of ligands and the complexes (Fig S5-S13) support the coordination of PLTSC (A) and dipeptides (B) to Ni(II) ion Assignments of the characteristic IR bands of the ligands and the ternary ... Vietnam Academy of Science and Technology, Hanoi & Wiley-VCH GmbH Synthesis, characterization and biological activity of mixed ligand chelates of Ni(II) with pyridoxalthiosemicarbazone and dipeptides ... Synthesis of mixed ligand Ni(II) complexes 0.4838 g (1.7 mmol) of PLTSC and 0.3293 g (1.7 mmol) of gly/0.3293 g (1.7 mmol) of gly-leu/0.4168 g (1.7 mmol) of gly-tyr/0.3048 g (1.7 mmol) of gly-val

Ngày tải lên: 28/06/2021, 10:18

... dependence of the storage and loss moduli of chitin-like EPS-based solu-tion at concentrasolu-tions of A) 5 mg mL−1, B) 10 mg mL−1and C) 15 mg mL−1of chitin in LiCl and D) 5 mg mL−1, E) 10 mg mL−1and ... decreases, while the increase of the intensity of amide I band indicates the formation of NH2groups The EPS showed a higher in-tensity band of amide I than the band of amide II, suggesting an e ... flow rate of 0.6 mL min−1); C) Deacetylated EPS (Red) and native EPS (Black) FTIR spectra, and D) GCMS of EPS product of total hydrolysis vs.D-glucosamine standard (For interpretation of the references

Ngày tải lên: 01/01/2023, 12:48

... axygenation of other tissues [2] and acting as a storshouse for minerals where 99% of the calcium, 85% of the phosphate and 50% of the magnesium are stored in bones [3] The bones of the adult ... compliance of three important biological propertios The first property slates tha ability to support the attachment of osteoblast and osteogenic cells and allow the migration and ingrowth of these ... considerable time, a great deal of tescarch offorl has boon dedicated lo enhancing the bioactivity of the bone-implanted materials and ensuzing, the continuous progress of techniques that can adapt

Ngày tải lên: 11/06/2025, 21:05

... 3.2 Biological activity of Si02-1 nanomaterials Trang 12TABLE OF CONTENTS CHAPTER 1 OVERVIEW OF RESEARC 1.1 Overview of bone tissuc forming techniques, 1.1.1 Structure and role of bones ... 3.2 Biological activity of Si02-1 nanomaterials Trang 16TABLE OF CONTENTS CHAPTER 1 OVERVIEW OF RESEARC 1.1 Overview of bone tissuc forming techniques, 1.1.1 Structure and role of bones ... Finally, and most importanlty, to my caring, loving and supportive family -Claudia, Laura and Ruud-, my heartfelt thanks, You were always avaliable whenever I need a helping hand and a word of encouragement

Ngày tải lên: 19/06/2025, 21:51

... inspection of physicochemical properties and SAR, it was observed that the presence of electron donating groups, number of hydrogen bond formation, lipophilicity of ligands and coulson charge of nitrogen ... synthesis and biological evaluation of antimalarial activity of new derivatives of 2,4,6‑s‑triazine Mallika Pathak1,2, Himanshu Ojha2,3*, Anjani K. Tiwari2, Deepti Sharma3, Manisha Saini1 and Rita Kakkar2 ... consisted of 10.4 g of RPMI-1640 with 40 mg of gentamicin and 5.94 g of HEPES buffer The culture medium was reconstituted just before use by pouring sterile 5% sodium bicarbonate in ratio of 1:24 and

Ngày tải lên: 29/05/2020, 12:43

... composition and structure of products 4a–d were confirmed by the results of elemental analysis and data of IR and NMR spectra The infrared of structure 4 displayed absorption band assignable ... representative panel of fungal strains i.e Aspergillus fumigatus, and Candida albicans The organisms were tested against the activity of solutions of concentrations (1  mg/mL) and using inhibition ... carbon and sulfur atoms, respectively, of the isothi-ocyanates and their extended π electron system make them unique precursors of a large variety of target mol-ecules Consequently, many classes of

Ngày tải lên: 29/05/2020, 14:57

... bonds between NH of Thr5 and CO of Arg2, as well as NH of Arg2 and CO of Thr5 Structure of cyclic hexapeptides – cYT peptide The NMR data of the cYT peptide were indicative of its flexible nature ... biological activity and to study the effect of reducing the chain length of peptides on Ó FEBS 2004 Design of peptides for T-cell adhesion inhibition (Eur J Biochem 271) 2879 biological activity, ... intensity of ROE cross-peaks, and were assigned as strong, medium and weak ˚ represent the family Based on ROE violation > 0.2 A and allowed values of /, w in the Ramachandran map, only one family of...

Ngày tải lên: 19/02/2014, 13:20

... [19], bone marrow [10] and several other organs [20] However, the main host cells and the target organs of this virus are still undefined The study of the biological functions of TTV is particularly ... interactions, and to find permissive cell lines for further molecular and cell biological studies of this peculiar human virus For this purpose, we have cloned and sequenced the full-length genome of TTV ... SalI double-digestions of the input linear construct yielded three restriction fragments of approximately 2100, 740 and 890 bp with the first enzyme pair, and of 2200, 630 and 890 bp with the latter...

Ngày tải lên: 16/03/2014, 05:20

... analysis of the calculated structures revealed a short distances between NH of Leu7 and the side chain carboxyl group of the Asp6 residue (< 0.28 nm), and NH of Leu7 residue and C¼O of Leu5 (< ... of a potent endozepine antagonist (Eur J Biochem 268) 6049 Fig RP-HPLC monitoring of N- and C-terminal deprotections and on-resin cyclization of the linear precursor of cyclo128 OP Aliquots of ... the receptor affinity and selectivity of peptide ligands [13,14,27] The Ala-scan of OP has revealed that the side chain of each residue is required for the full activity of the peptide [12] These...

Ngày tải lên: 24/03/2014, 04:21

... markers [alkaline phosphatase (ALP) and sucrase-isomaltase] and the rate of proliferation, and by electron-microscopic examination As shown in Fig 1A, the levels of ALP and sucrase-isomaltase in RPMI ... affect biological and laser light scattering measurements, we first explored whether the presence of phosphate was necessary for the biological effect of CPP To this end, a first dose–response set of ... individual CPPs, b-CN(1–25)4P and as1-CN(59–79)5P, (A) and (C), respectively, and of a mixture of CPPs (CPP DMV) (B) Each point on the graphs corresponds to the mean value of the [Ca2+]i peak rise...

Ngày tải lên: 16/03/2014, 05:20

... isolated from the stem bark of Hopea consist of dimer, trimer and tetramer resveratrol Some compounds have biological activity as antioxidant and cytotoxic effect against Raji and HeLa-S3 cell lines ... For oligoresveratrol, that activity as hydroxyl radical scavenger was due to the existence of phenol ring, stability of molecular structure and existence of double bonds of olefinic unit Phenol ... (rings of A1 and C1), and one unit of a 1,2,4-trisubstituted benzene at δ 6.07 (1H, d, J = 2.6 Hz); 6.02 (1H, d, J = 8.4 Hz) Additionally, the 1H NMR spectrum exhibited signals for a set of aromatic...

Ngày tải lên: 07/08/2014, 14:20

... RGD and GFOGER (Knight et al., 1998; Knight et al., 2000), may result in the loss of full biological activity because of the absence of supplementary functional domains, such as synergy sites and ... diversity of collagen families makes development of a comprehensive, single model system challenging A system capable of emulating specific variables, such as the structure and biological activity, of ... chromatograms of purified (a) PT-CMP1, (b) PT-CMP2, (c) PT-CMP3, and (d) PT-CMP4 and their respective MALDI-TOF MS spectra (left) HPLC buffer gradient is from 90 %A and 10 %B to 55 %A and 45 %B in...

Ngày tải lên: 12/09/2015, 08:20