7 definition of the response to treatment

... intestine transit in these patients Therefore, the objective of this study is to investigate the symptomatology of bloating, the role of gastrointestinal transit and effect of tegaserod in non-diarrhea ... diffusion into the blood and for bacterial consumption Therefore, the rate of gas transit is a critical factor that influences the volume and composition of gas in the different regions of the gut ... cell of the gut is distributed to the rest of the body, except CNS, since 5-HT does not cross the blood-brain barrier 5-HT neurons are 36 restricted to clusters of cells around the midline of pons...

Ngày tải lên: 26/09/2015, 10:05

... Ed (X ) the expectation of phenotypes among the offspring of the w-selected parents The numerator is the response R(w, X) to selection based on the fitness function w in the trait X of interest, ... predictions of the response to selection and to compare several selection criteria In a second step we check the validity of the theoretical approach by means of simulations and test the ability of the ... following the on one hand, and on Gaussian model these terms One has E(7!M,f) = M(u, v) , the other hand then the expectation of the above Putting (1) together expression equals leads to the denominator...

Ngày tải lên: 09/08/2014, 18:21

... yeast to the absence of telomerase [22], the DDR [27] and the ESR [24] Furthermore, the response to uncapped telomeres in cdc13-1 budding yeast strains has features in common with the responses to ... in the DDR, showing that the response to uncapped telomeres is not identical to the response to DSBs at non-telomeric loci The response to telomerase deletion was also sufficiently different to ... a common feature in response to telomere damage Induction of a stress response may be a conserved feature of the response to telomere damage A major feature of the response to telomere damage...

Ngày tải lên: 14/08/2014, 21:20

... to both metabolic inhibitors (3BrP and IA) decreased as the bioenergetic signature of the cells increased Thus, the lower the bioenergetic signature of a cell the greater the death response to ... activation of caspase (an apoptotic indicator) was observed following any of these above treatments in any of the cell lines tested (data not shown) Therefore, inhibition of the activity of glycolytic ... with the potential to execute necrosis in response to treatments with glycolytic inhibitors In contrast, the bioenergetic signature directly correlates with the apoptotic response to 5-FU treatment...

Ngày tải lên: 18/06/2014, 19:20

... periods of time (Fig 3) As shown, the addition of stressors to the cultures inhibits growth without killing the cells The hybridizing band in the northern analysis showed the expected size of about ... role in the detoxification processes In this study we examined the role of Bcp2 in order to increase the knowledge of the enzymatic activity involved in the oxidative stress in S solfataricus To detect ... that the protein can shift from a monomer to a multimeric form depending on the protein concentration and the temperature On the basis of the data reported in the literature on the structure of...

Ngày tải lên: 07/03/2014, 12:20

... and to meet the specific needs of assessing bisphosphonate treatments for osteoporosis The objective of the current study was to evaluate the psychometric properties of the OPSAT-Q and, therefore, ... addition to the OPSAT-Q OPTQoL The OPTQoL is a validated instrument used to assess the impact of osteoporosis on a patient's quality of life [12,13] For the psychometric evaluation study of the OPSAT-Q, ... 31 to 100 and 42 to 100, respectively The range for the CSS was 44 to 100 The percentage of subjects scoring at the floor was 1% for all subscales and composite scores Among the subscales, the...

Ngày tải lên: 20/06/2014, 15:20

... Ovariectomy was performed using a dorsal midline incision and the entrance into the abdominal cavity was made with a small cut in to the muscle half to two-thirds of the way down the side of the ... Overall, there are a series of situations where CTXII behaves distinctly to other markers The present study adds to these series the unique response of CTX-II to oestrogen deficiency There are ... levels of ovariectomy-rats were back to the control levels of sham-operated rats The present study aims to investigate the relevance of CTX-II to cartilage collagen metabolism in situations of oestrogen...

Ngày tải lên: 09/08/2014, 01:22

... Ovariectomy was performed using a dorsal midline incision and the entrance into the abdominal cavity was made with a small cut in to the muscle half to two-thirds of the way down the side of the ... Overall, there are a series of situations where CTXII behaves distinctly to other markers The present study adds to these series the unique response of CTX-II to oestrogen deficiency There are ... levels of ovariectomy-rats were back to the control levels of sham-operated rats The present study aims to investigate the relevance of CTX-II to cartilage collagen metabolism in situations of oestrogen...

Ngày tải lên: 09/08/2014, 13:22

... investigated whether the observed changes were related to the magnitude of IFN response gene expression prior to treatment Therefore, the relationship between the extent of the baseline IFN response ... in DAS28 of at least 1.2) [17] According to the EULAR response criteria, of the 33 patients had a poor response whereas 12 patients displayed a good response to treatment An overview of the patients' ... divergent outcome of the IFN response activity might be a consequence of differences Page of 10 in the relative contribution of each of these processes in the regulation of IFN response activity...

Ngày tải lên: 12/08/2014, 11:22

... the moment of the contraction Under these circumstances the effects of the changes of the acceleration of the load on the contraction can be traced Effect of the acceleration of the load on the ... shown that, at parity of the force F2, the decrease of the acceleration of the load (and the corresponding increase of the mass) decreases the initial F1 required to start the contraction In our ... b Effects of the acceleration of the load on the initial stiffness of the active half sarcomere In this section we show that the decrease of the acceleration of the load (at parity of load force)...

Ngày tải lên: 13/08/2014, 16:20

... in the Venn diagram is divided into subsets by the direction of the response in the different comparisons The formation of dots in the squares shows the general tendency of the response, with the ... profile from that of the members of cluster Expanding the examination of the co-regulated groups of genes, information was used on the physical location of the genes on the genomic scaffolds to ... shown to be dependent on pH [13] Therefore, to expand on the results of the model-driven investigation of the organic acid response to pH, a physiological characterization and transcriptome analysis...

Ngày tải lên: 14/08/2014, 21:20

... ACN) and 0,7 µl of peptide solution spotted on the MALDI-target directly Prior to the measurement in the MALDI-TOF/TOF instrument the samples were allowed to dry on the target 10 to 15 23 Materials ... on the area and pixel intensities of spots The relative intensity of each spot (% volume) was determined by dividing the intensity of the spot by the sum of the intensities of all spots in the ... characteristic of these comparative LC-MS procedures is that they not rely on the use of stable isotopes; therefore the procedure is often referred to as label-free LC-MS Major advantages of label-free...

Ngày tải lên: 12/05/2016, 21:57

... “total quantity control.”89 The 2008 LPCWP requires the governments of the provinces, autonomous regions, and municipalities to implement a system of total quantity control of the discharge of ... now consider the total amount of pollutant discharged (instead of just concentration) In July of 2008, MEP sought to delay the release of permits to have more time to “make public the legislative ... subject to regulatory protection.35 In addition to the LPCWP, polluting industries are subject to a variety of rules and regulations Nationally, these include the Implementing Rules on the Law on the...

Ngày tải lên: 18/02/2014, 04:20

... Portrait of Napoleon TO THE VETERANS OF THE GRAND ARMY COMRADES, I have undertaken the task of tracing the History of the Grand Army and its Leader during the year 1812 I address it to such of you ... inheritance of glory which had been left them by the great Frederick, or by the wish of blotting out the disgrace of the campaign of 1792, entered heartily into the views of the allied powers; but the ... policy of the king, and of his minister Haugwitz, resisted them, until the violation of the Prussian territory, near Anspach, by the march of a corps of French troops, exasperated the passions of the...

Ngày tải lên: 06/03/2014, 03:21

... However, the Special Rapporteur reminds all States of their positive obligation to promote or to facilitate the enjoyment of the right to freedom of expression and the means necessary to exercise ... views regarding the compatibility of blocking child pornography on the Internet with the right to freedom of expression in the context of discussions on the proposal for a directive of the European ... addendum to this report (A/HRC/17/27/Add.3) 14 From to April 2011, the Special Rapporteur visited the Republic of Hungary, at the invitation of the Government, to provide expert advice to the Government...

Ngày tải lên: 06/03/2014, 21:20

... Analysis of the Protection of the Right to Education by International Law 11 Chapter Two: History and Nature of the Right to Education 17 Chapter Three: The Right to Education and the Disputed ... who wrote the second rapporteurs report on the thesis Then I would like to thank Dr Richard Lord of the University of Cape Town, South Africa, a friend of mine, for having proof-read the script ... agreements, the failure of a state to comply with the right to education amounts to a violation of international law, entailing the international responsibility of the state The Aims of this Book...

Ngày tải lên: 30/03/2014, 10:20

... overarching theme of PREFACE xiii the book is the importance of time to every aspect of good medicine Sufficient time is required to learn to heal, to teach how to heal, to practice the art of healing, ... threatened—that is the central concern of the story told in the following pages k • k • k This book is intended to provide a synthetic history of American medical education from the turn of the twentieth ... preferred the use of the term “university system” to “full-time system.” To the joy of medical educators, the new identity of medical education as a university discipline carried a profound payoff: the...

Ngày tải lên: 03/06/2014, 01:25

... standard deviation of the remainder of the assets of the firm If the standard deviation of the existing assets of the firm is higher than the standard deviation of the new project, then the new project ... redeployers In the event of the bad state of the world occurring, these asset redeployers change the use of the asset and generate cash thereby creating value Debt therefore acts as a means of transferring ... money’ options and thereby maximize the value of the firm However, stockholders will not exercise their ‘in the money’ options when their payoff transfers most of the value to debt holders, a...

Ngày tải lên: 03/06/2014, 02:15

... guide for others in the field to validate these and other similar assays for assessment of patient T cell response These methods can be applied not only to cancer vaccines but to other therapeutic ... due to an insufficient number of cells Accuracy The accuracy of an analytical method describes the closeness of mean test results (detected) obtained by the method to the true value (expected) of ... alteration or interference in response due to the presence of unintended analytes or other interfering substances in the sample Due to the lack of a standard reference material to establish a true value,...

Ngày tải lên: 18/06/2014, 15:20