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Human genetics concepts and applications 11th edition ricki lewis test bank

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Remember Learning Outcome: 02.08 Describe the events and control of the cell cycle.. Remember Learning Outcome: 02.08 Describe the events and control of the cell cycle.. Remember Lear

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1 The cellular basis of muscular dystrophy is that some of a child's muscle cells

A have combined into a structure that cannot contract

Bloom's Level: 02 Understand

Learning Outcome: 02.01 Explain why it is important to know the cellular basis of a disease

Section: 02.01

Topic: Cell parts

2 A researcher identifies an abnormality in a protein that causes a particular inherited illness

To develop a treatment, it would be most helpful to know

A which cells are affected and how to replace the protein's function in them

B the sequence of the gene that encodes the protein

C the other types of molecules that cause or contribute to the disease

D the type of mutation that affects the protein

Bloom's Level: 03 Apply

Learning Outcome: 02.01 Explain why it is important to know the cellular basis of a disease

Section: 02.01

Topic: Cell parts

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3 Which of the following statements is true?

A Somatic cells are diploid, meaning that they have two copies of the human genome

B Somatic cells are haploid, meaning that they have one copy of the human genome

C Sperm and egg cells are diploid, meaning that they have two copies of the human genome

D Stem cells are haploid, meaning that they have one copy of the human genome

Bloom's Level: 02 Understand

Learning Outcome: 02.02 Define differentiated cell

Section: 02.01

Topic: Cell parts

4 Which of the following types of components aggregate and interact to form the epithelial, connective, muscle, and nerve tissues in the human body?

Bloom's Level: 01 Remember

Learning Outcome: 02.02 Define differentiated cell

Section: 02.01

Topic: Differentiation

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Bloom's Level: 02 Understand

Learning Outcome: 02.04 Describe how organelles interact

Bloom's Level: 01 Remember

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

7 The major macromolecules that make up cells are

A vitamins and minerals

B carbon, hydrogen, nitrogen, oxygen, and phosphorus

C carbohydrates, proteins, lipids, and nucleic acids

D eukaryotes, prokaryotes, and archaea

Bloom's Level: 01 Remember

Learning Outcome: 02.03 List the four major chemicals in cells

Section: 02.02

Topic: Cell parts

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Bloom's Level: 01 Remember

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

9 Organelles protect a cell by

A

sequestering biochemicals that could dismantle other cellular structures

B forming a thick outer barrier

C containing powerful enzymes that kill any bacteria that enter

D

placing flag-like molecules on a cell's surface, which identify that cell as belonging to a particular person

Bloom's Level: 02 Understand

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

10 The nuclear lamina is

A the sac that holds the genetic material

B part of the nucleus that holds RNA

C a fibrous layer that lines the inner face of the nuclear membrane

D the site of protein synthesis

Bloom's Level: 02 Understand

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

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11 In a human cell, the genetic material is in the

Bloom's Level: 01 Remember

Learning Outcome: 02.03 List the four major chemicals in cells

Bloom's Level: 02 Understand

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

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13 What is the sequence of events involved in the production of proteins that is secreted?

A A hormone signals the gene that encodes the protein to be transcribed into mRNA in the

nucleus The mRNA is translated into protein on the ER, then processed and folded in the Golgi apparatus, and then sent out of the cell in a vesicle

B A hormone signals a protein-filled vesicle to move from the plasma membrane into the cell and into the nucleus, where it stimulates transcription of the appropriate gene into mRNA The mRNA exits the nucleus and is translated into protein on the ER and processed and folded in the Golgi apparatus Finally, the protein is transported out of the cell in a vesicle

C A hormone binds to the plasma membrane, signaling proteins near the membrane to fall apart into amino acids These enter the nucleus and stimulate replication of the gene encoding the protein

D The protein is produced as a linear molecule in the nucleus, then exits through nuclear pores On the ER the protein folds into its active form and at the Golgi apparatus is packed into a vesicle, which carries it across the plasma membrane and out of the cell

Bloom's Level: 01 Remember

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

14 The organelle that consists of a stack of flat, membrane-enclosed sacs is the

Bloom's Level: 02 Understand

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

15 The organelle that is the equivalent of a cellular garbage disposal system is the

Bloom's Level: 02 Understand

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

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Bloom's Level: 02 Understand

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

17 In mitochondria,

A energy from nutrients is converted into a form that a cell can use

B all of a cell's DNA is replicated

C fats and carbohydrates are degraded

D sugars are added to proteins

Bloom's Level: 01 Remember

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

18 The cell type with the most mitochondria is

Bloom's Level: 02 Understand

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

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19 Cristae are

A types of genes

B types of insects

C membranous structures that are parts of mitochondria

D bits of sugars in the Golgi apparatus

Bloom's Level: 01 Remember

Learning Outcome: 02.04 Describe how organelles interact

Section: 02.02

Topic: Cell parts

20 In a DNA molecule, the sugar-phosphate backbone is the same in everyone, but the base sequence is different in everyone A plasma membrane is similar conceptually to DNA in that

A the lipid bilayer is the same in everyone, but the nature and pattern of the molecules

embedded in it differ

B the pattern of embedded proteins in the plasma membrane is the same in everyone, but the lipid bilayer differs

C the lipid bilayer and pattern of embedded proteins differ in everyone

D the lipid bilayer is the same in everyone, but some people have the embedded proteins sticking out of the outer face of the membrane, and others have the proteins extending inward

Bloom's Level: 04 Analyze

Learning Outcome: 02.05 Describe the structure and function of a biological membrane

Section: 02.02

Topic: Cell parts

21 Which sequence of events illustrates the steps of signal transduction?

A First messenger to receptor molecules to second messenger to cellular response

B Receptor molecules to first messenger to second messenger to cellular response

C First messenger to second messenger to receptor molecules to cellular response

D First messenger to second messenger to cellular responses to receptor

Bloom's Level: 04 Analyze

Learning Outcome: 02.05 Describe the structure and function of a biological membrane

Section: 02.02

Topic: Cell parts

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Bloom's Level: 01 Remember

Learning Outcome: 02.05 Describe the structure and function of a biological membrane

Section: 02.02

Topic: Cell parts

23 The internal scaffolding of a cell consists of

A microtubules and microfilaments

B cilia and flagella

C chitin and chlorophyll

D lipid bilayers

Bloom's Level: 01 Remember

Learning Outcome: 02.06 List the components of the cytoskeleton

Section: 02.02

Topic: Cell parts

24 Cilia are built of

Bloom's Level: 01 Remember

Learning Outcome: 02.06 List the components of the cytoskeleton

Section: 02.02

Topic: Cell parts

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Bloom's Level: 02 Understand

Learning Outcome: 02.04 Describe how organelles interact

Bloom's Level: 02 Understand

Learning Outcome: 02.06 List the components of the cytoskeleton

Section: 02.02

Topic: Cell parts

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27 The approximate percentage of our cells that are replaced daily is

Bloom's Level: 01 Remember

Learning Outcome: 02.08 Describe the events and control of the cell cycle

A interphase and prophase

B interphase and mitosis.

C mitosis and meiosis

D mitosis and apoptosis

Bloom's Level: 01 Remember

Learning Outcome: 02.08 Describe the events and control of the cell cycle

Section: 02.03

Topic: Cell division and death

29 The cell cycle is a series of events a cell undergoes as it prepares to

A divide

B die

C adhere to another cell

D pass along a signal

Bloom's Level: 01 Remember

Learning Outcome: 02.08 Describe the events and control of the cell cycle

Section: 02.03

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Bloom's Level: 02 Understand

Learning Outcome: 02.08 Describe the events and control of the cell cycle

Section: 02.03

Topic: Cell division and death

31 The order of events in the cell cycle is

Bloom's Level: 04 Analyze

Learning Outcome: 02.08 Describe the events and control of the cell cycle

Section: 02.03

Topic: Cell division and death

32 At the point in the cell cycle when mitosis begins

A DNA replication begins

B each chromosome consists of two identical chromatids joined at the centromere

C

the number of chromosome is reduced to half

D the cell enters a dormant phase

Bloom's Level: 02 Understand

Learning Outcome: 02.08 Describe the events and control of the cell cycle

Section: 02.03

Topic: Cell division and death

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Bloom's Level: 01 Remember

Learning Outcome: 02.08 Describe the events and control of the cell cycle

Bloom's Level: 01 Remember

Learning Outcome: 02.08 Describe the events and control of the cell cycle

Section: 02.03

Topic: Cell division and death

35 During S phase, replicated chromosomes are joined at their

Bloom's Level: 02 Understand

Learning Outcome: 02.08 Describe the events and control of the cell cycle

Section: 02.03

Topic: Cell parts

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36 The part of a chromosome that shortens with each cell division, functioning as a "clock,"

Bloom's Level: 01 Remember

Learning Outcome: 02.08 Describe the events and control of the cell cycle

Section: 02.03

Topic: Cell division and death

37 Factors that control how often a cell divides include

A telomere lengths, hormonal signals, crowding, and growth factors

B which chromosomes are active and which are not

C the activity level of the person, diet, and environmental exposures

D where chromosomes are located within the nucleus

Bloom's Level: 02 Understand

Learning Outcome: 02.08 Describe the events and control of the cell cycle

Section: 02.03

Topic: Cell division and death

38 During apoptosis, caspases

A activate enzymes that cut DNA into same-sized pieces

B cause mitochondria to replicate their DNA

C alter the cell surface so that viruses can more easily enter

D remove introns from DNA

Bloom's Level: 02 Understand

Learning Outcome: 02.07 Distinguish between mitosis and apoptosis

Section: 02.03

Topic: Cell division and death

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39 Apoptosis is a form of

A programmed cell death that is a normal part of development

B programmed cell division that is a normal part of development

C

cellular duplication

D cellular adhesion

Bloom's Level: 01 Remember

Learning Outcome: 02.07 Distinguish between mitosis and apoptosis

Section: 02.03

Topic: Cell division and death

40 The defining characteristic of a stem cell is

Bloom's Level: 01 Remember

Learning Outcome: 02.09 List the characteristics of a stem cell

Section: 02.04

Topic: Stem cells

41 A difference between a stem cell and a progenitor cell is that

A a progenitor cell cannot self-renew and a stem cell can

B a stem cell cannot self-renew and a progenitor cell can

C progenitor cells are rare but stem cells are abundant

D progenitor cells are not present in embryos but stem cells are

Bloom's Level: 02 Understand

Learning Outcome: 02.10 Define stem and progenitor cell

Section: 02.04

Topic: Stem cells

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42 A cell that can divide to give rise to any cell type, including those of membranes that support the developing embryo, is

Bloom's Level: 02 Understand

Learning Outcome: 02.09 List the characteristics of a stem cell

Section: 02.04

Topic: Stem cells

43 An experimental treatment for amyotrophic lateral sclerosis (Lou Gehrig's disease), which causes gradual loss of the ability to move, sends four genes into cells sampled from a patient's skin This procedure reprograms the cells, which are then exposed to molecules and genes that stimulate them to develop as healthy versions of the cells affected in the disease These cells are implanted into the patient They are

A embryonic stem cells

B adult connective tissue stem cells

C induced pluripotent stem cells

D apoptotic cells

Bloom's Level: 04 Analyze

Learning Outcome: 02.10 Define stem and progenitor cell

Section: 02.04

Topic: Stem cells

44 Human embryonic stem cells that are used in research are

A cultured in the bodies of human embryos from outer cell mass cells

B cultured in laboratory dishes from inner cell mass cells taken from a 5-day embryo

C taken from aborted human fetuses between 10 and 12 weeks of gestation

D taken from stillbirths that do not have genetic diseases

Bloom's Level: 02 Understand

Learning Outcome: 02.09 List the characteristics of a stem cell

Section: 02.04

Topic: Stem cells

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45

"Adult" stem cells are more accurately called tissue-specific or somatic stem cells because

A they are also present at prenatal stages of development.

B some adults do not have them

C whether they are present or not in an adult depends upon the individual's level of maturity

D an adult body also contains embryonic stem cells

Bloom's Level: 02 Understand

Learning Outcome: 02.09 List the characteristics of a stem cell

Section: 02.04

Topic: Stem cells

46 Human stem cells are valuable in drug development because they can be used to

A create experimental organisms, such as rats and mice

B replace experimental animals such as rats and mice

C grow human embryos in culture, on which drugs can be tested

D study the latest stages of the disease that would have unfolded if the person hadn't died

Bloom's Level: 02 Understand

Learning Outcome: 02.09 List the characteristics of a stem cell

Section: 02.04

Topic: Stem cells

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Bloom's Level: 01 Remember

Learning Outcome: 02.11 How can the bacteria that live in and on our bodies affect our health?

Section: 02.05

Topic: The human microbiome

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48 Which of the following is a cure for people with recurrent infection from Clostridium difficile?

Bloom's Level: 02 Understand

Learning Outcome: 02.11 How can the bacteria that live in and on our bodies affect our health?

Section: 02.05

Topic: The human microbiome

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