The learning objectives for this chapter include: Describe the structure, location, and functions of the kidney; explain how nephrons filter blood and form urine; compare the locations, structures, and functions of the ureters, bladder, and urethra; describe the causes, signs and symptoms, and treatments of various diseases and disorders of the urinary system.
Trang 1The Urinary System
Trang 2Learning Outcomes (cont.)
31.1 Describe the structure, location, and
functions of the kidney
31.2 Explain how nephrons filter blood and
form urine
Trang 3Learning Outcomes (cont.)
31.3 Compare the locations, structures, and
functions of the ureters, bladder, and urethra.
31.4 Describe the causes, signs and
symptoms, and treatments of various
diseases and disorders of the urinary
system
Trang 4• System functions to remove waste products
from the blood
• Nephrons filter the blood and form the urine
Kidneys
Ureters
Bladder
Urethra
Trang 6The Kidneys (cont.)
– Expansion of the ureter
– Divides into calyces
Kidney
Trang 7• Renal cortex – outermost layer
• Renal medulla
– Middle portion
– Divides into renal pyramids
• Renal column – between pyramids
The Kidneys (cont.)
Kidney
Trang 10Nephrons (cont.)
Afferent arterioles
Renal artery
Efferent arterioles
Efferent arterioles
Peritubular Capillaries
Peritubular Capillaries
Renal vein
Nephron
Glomerulus
Trang 11Apply Your Knowledge
What is the function of the kidney?
ANSWER: Maintain hemostasis by removing metabolic
waste products from the blood, secreting erythropoietin
to help regulate RBC production, and secreting renin to
help regulate the BP.
Correct!
Trang 12Urine Formation
• Glomerular Filtration
– Occurs in renal corpuscles
– Fluid part of the blood
• Into Bowman’s capsule
• Becomes glomerular filtrate
Glomerulus
Trang 13Urine Formation (cont.)
• Glomerular filtration
– Filtration pressure – that needed to force
filtrate from the glomerulus into Bowman’s capsule
– Rate of filtration
• Sympathetic nervous system control
• Constriction of afferent arterioles
Glomerulus
Trang 14Tubular Reabsorption
• Glomerular filtrate proximal convoluted
tubule
• Reabsorption of needed substances
• Water reabsorption hormonal regulation
– Antidiuretic hormone (ADH)
– Aldosterone
water reabsorption, urine production
Tubular Reabsorption
Trang 15Tubular Secretion
Trang 16Urine Composition
• Mostly water
• Urea and uric acid
• Trace amounts of amino acids and various
ions
• Secretion of waste products helps to
maintain the acid-base balance
Trang 17Apply Your Knowledge
Match the following:
_ Second process in urine formation
_ Substances move from blood
into renal tubules reabsorption
_ Depends on filtration pressure
_ Third process of urine formation
_ First process of urine formation
_ Filtrate flows into the proximal convoluted tubule
C Tubular Secretion
Trang 18Urinary Bladder
• Trigone – triangle on internal floor of bladder
• Detrusor muscle – smooth muscle of bladder
Trang 19Stretch receptors
Spinal cord
Parasympathetic nerves stimulate detrusor muscle
Brain stem and cerebral cortex
Trang 20• Moves urine from the bladder to the outside
world
• Shorter in females – patient education
– Urinate when urge occurs
– Drink adequate clear fluids
– Wipe front to back
– Urinate after intercourse
Urethra
Trang 21True or False:
_ Ureters move urine by peristalsis.
_ The detrusor is formed by the openings of the ureters
and urethra.
_ The process of micturition is triggered when the bladder contains about 150 ml urine.
_ The urethra move urine from the kidney to the bladder.
_ The urethra is longer in females.
_ Contraction of the detrusor muscle pushes urine from
T
ANSWER:
trigone
Trang 22Diseases and Disorders of the Urinary System
(renal) failure Kidneys slowly lose ability to function; not reversible
Cystitis Urinary bladder infection; more
common in females
Trang 23Diseases and Disorders of the Urinary System
Disease/Disorder Description
Glomerulonephritis Inflammation of the glomeruli of
the kidney; one cause of chronic renal failure
Incontinence Inability to control urination
Polycystic kidney
disease Enlargement of kidneys because of the presence of
many cysts within them; slow, progressive disease
Trang 24Diseases and Disorders of the Urinary System
Disease/Disorder Description
Pyelonephritis Complicated urinary tract
infection; begins with a bladder infection and spreads to both kidneys; can be acute or chronic
Renal calculi Kidney stones; can become
lodged in ducts within kidneys
or ureters
Trang 25Apply Your Knowledge
Matching:
_ Complicated urinary tract infection A Pyelonephritis
_ Inability to control urination B Glomerulonephritis
_ Kidney stones C Incontinence
_ Slow loss of kidney function D Chronic renal failure
_ Bladder infection E Renal calculi
_ Inflammation of the glomeruli F Cystitis
_ Kidney enlargement due to cysts G Acute renal failure
_ Sudden loss of kidney function H Polycystic kidney disease
D J O B
!
Trang 26In Summary
31.1 The retroperitoneal kidneys are
composed of the outer renal cortex and inner renal medulla
Their function is to remove metabolic wastes from the body
Trang 27In Summary
31.2 A nephron is a single kidney cell
It is composed of a renal corpuscle composed
of the glomerulus and the Bowman’s capsule and the three sections of the renal tubule: the proximal convoluted tubule, the loop of Henle, and the distal convoluted tubule
The nephrons filter blood and form urine through three processes: glomerular
filtration, tubular reabsorption, and tubular secretion
Trang 28In Summary (cont.)
31.3 The ureters are long tubes extending from
each renal pelvis that bring urine to the bladder for storage
The urethra is the muscular tube extending from the bladder that allows urine to be expelled from the body
Trang 29In Summary (cont.)
31.4 There are many common diseases and
disorders of the urinary system with varied signs, symptoms, and treatments
Some of these include acute kidney (renal) failure, chronic kidney (renal)
failure, cystitis, glomerulonephritis,
incontinence, polycystic kidney disease,
pyelonephritis, and renal calculi.
Trang 30End of Chapter 31
This too shall pass—just
like a kidney stone.
~H Madson