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Frush, MD Division of Pediatric Radiology, Department of Radiology, Duke University Health System, 1905 McGovern-Davison Children’s Health Center, Box 3808, Erwin Road, Durham, NC 27710,

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distress usually proceed to surgery Older children

and adults with recurrent pneumonia are also

re-commended for surgery The management of those

patients with a radiologic CCAM who remain

asymp-tomatic is less clear-cut Certainly, there is a risk of

infection developing in a CCAM and there are also

several case reports of malignancy arising in CCAM Bronchoalveolar carcinoma, pleuropulmonary blas-toma, rhabdomyosarcoma, and bronchogenic carci-noma have all been reported [6,15,21 – 26] Some authors advocate surgery in these patients, to eradi-cate the risk of future infection or tumor Other

Fig 4 (A) Type II congenital cystic adenomatoid malformation in an asymptomatic neonate (antenatal diagnosis) Chest radiograph shows a hazy opacity in the right lower lobe and upward bowing of the minor fissure (B) CT chest (lung windows) confirms the presence of several small cysts in the right lower lobe This infant was managed conservatively.

Fig 3 (A) Type I congenital cystic adenomatoid malformation in a 12-month-old boy who presented with shortness of breath Chest radiograph shows a hyperlucent right hemithorax, with contralateral shift of the heart and mediastinal structures Sparse lung markings are seen in the right hemithorax (From Donnelly LF Chest In: Fundamentals of pediatric radiology Philadelphia: WB Saunders; 2001 p 38.) (B) CT scan of the chest (lung windows) demonstrates a large cyst filling the right hemithorax The compressed right middle lobe is seen behind the sternum.

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Technique of Pediatric Thoracic CT Angiography

Donald P Frush, MD

Division of Pediatric Radiology, Department of Radiology, Duke University Health System,

1905 McGovern-Davison Children’s Health Center, Box 3808, Erwin Road, Durham, NC 27710, USA

One of the principle applications derived from the

evolution of multidetector row CT (MDCT), initially

seen with 16-slice and currently up to 64-slice CT, is

CT angiography The ease, safety, and quality of the

examinations compared with traditional angiography

were quickly recognized, and the value of CT

angiography firmly established For a variety of

reasons, the earliest MDCT angiography with

single-slice technology was problematic for the pediatric

population[1 – 4] Some of these problems included

breathing artifact in children who could not hold their

breath, small volumes of contrast material, relatively

slow and inconsistent rates of injection, and small

cardiovascular structures [4] Although these same

issues currently exist with pediatric CT angiography,

much faster scanning and isotropic display with

submillimeter image thickness have, to a large extent,

minimized the impact of these factors Nevertheless,

it is still important to understand the special

consid-erations with pediatric CT angiography[5] In trying

to make a potentially complex technique relatively

simple and practical, the following material is divided

into two parts: study preparation and study

perform-ance The format is essentially step-by-step (Box 1),

with the supporting technical information either cited

or included in tables Despite the fact this material

somewhat betrays the traditional academic format,

a greater benefit is served: excellent CT angiography

is possible in even the most problematic of

pediat-ric cases

Planning the pediatric CT angiogram Determine that CT angiography is the appropriate examination

In addition to CT angiography, considerations for thoracic cardiovascular structural and functional assessment include echocardiography, MR angiogra-phy and venograangiogra-phy, and conventional angiograangiogra-phy

CT angiography is advantageous in that it provides a more global assessment of cardiovascular structures and adjacent structures, such as the lung and airway The examination is also relatively quick to perform, with times that can approach 1 second given 64-slice technology Sedation is rarely necessary compared with MR imaging and echocardiography, and the examination quality is more consistent (operator in-dependent) CT angiography is a relatively non-invasive procedure, compared with angiography In addition, monitoring and direct observation of the patient are easier with CT angiography than with MR imaging Contraindications for MR imaging vascular assessment including pacemakers and recent surgical procedures with some metallic materials are not present with CT angiography Moreover, metal artifact is much less an issue with CT angiography than with MR angiography For a more in-depth dis-cussion of the relative merits and disadvantages with

CT angiography and MR angiography, the reader is referred to a recent series of reviews[5 – 8] There are disadvantages with CT angiography CT angiography requires administration of intravenous (IV) contrast media Adverse reactions, however, are singularly unusual in children In addition, nephro-toxicity from contrast media in children is much less

0033-8389/05/$ – see front matter D 2005 Elsevier Inc All rights reserved.

doi:10.1016/j.rcl.2004.09.013 radiologic.theclinics.com E-mail address: frush943@mc.duke.edu

Radiol Clin N Am 43 (2005) 419 – 433

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