Chapter 062. Principles of Human Genetics (Part 1) pdf

Human Genetics Part 1 Table 62-1 Selected Databases Relevant for Genomics and Genetic Disorders National Center for Biotechnology Information NCBI biology information, public databases

Human Genetics

(Part 1)

Table 62-1 Selected Databases Relevant for Genomics and Genetic Disorders

National

Center for

Biotechnology

Information (NCBI)

biology information, public databases,

computational

biology Software for analyzing genome data

Extensive links to other databases, genome resources, and tutorials

National

Human Genome

Research Institute

providing information about the human genome sequence, genomes

of other organisms, and genomic research

Ensembl

Genome browser

sequence information of eukaryotic

genomes

Online

Mendelian

Inheritance in Man

compendium of Mendelian

disorders and human genes causing genetic disorders

Office of

Biotechnology

Activities National

Institutes of Health

about recombinant DNA and gene transfer

Medical, ethical, legal, and social issues raised

by genetic testing

Medical, ethical, legal, and social issues raised

by xenotransplantation

American

College of Medical

Genetics

links to other databases relevant for the diagnosis, treatment, and prevention of genetic disease

Cancer

Genome Anatomy

Project (CGAP)

about gene expression profiles

of normal, precancer, and cancer cells

database resource for human genetics and telomere research

directory of genetic testing laboratories and prenatal diagnosis clinics

Reviews and educational materials

Genomes

Online Database

(GOLD)

on published and unpublished

genomes

HUGO Gene

Nomenclature

and symbols

MITOMAP, a

human

mitochondrial

genome database

compendium of polymorphisms and mutations of the human mitochondrial

DNA

Mitochondrial

disorders

http://www.neuro.wustl.edu/neuromuscular/mitosyn.html Overview

on clinical syndromes

associated with mtDNA mutations

DNA repeat

sequences & disease

http://www.neuro.wustl.edu/neuromuscular/mother/dnarep.htm Overview

on clinical syndromes

associated with DNA repeats

Online

Mendelian

Inheritance in

Animals (OMIA)

compendium of Mendelian

disorders in

animals

The Jackson

Laboratory

about murine models and the mouse genome

International

HapMap Project

of haplotypes in different ethnic groups relevant for association studies and

pharmacogenomics

Nuclear

Receptor Signaling

Atlas

nuclear receptors, coregulators, and

ligands

Dolan DNA

Learning Center,

Cold Spring Harbor

Laboratories

material about selected genetic disorders, DNA, eugenics, and genetic origin

The Online

Metabolic and

Molecular Bases of

Inherited Disease

(OMMBID)

version of the comprehensive text

on The Metabolic and Molecular Bases of Inherited Disease, 8e

genome-related databases have been published [Nat Genet 32(Suppl):1–79, 2002]