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Chapter 058. Anemia and Polycythemia (Part 5) pptx

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Anemia and Polycythemia Part 5 Normal blood smear Wright's stain.. High-power field showing normal red cells, a neutrophil, and a few platelets.. Severe iron-deficiency anemia.. Micro

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Chapter 058 Anemia and

Polycythemia

(Part 5)

Normal blood smear (Wright's stain) High-power field showing normal

red cells, a neutrophil, and a few platelets (From Hillman et al.)

Figure 58-4

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Severe iron-deficiency anemia Microcytic and hypochromic red cells

smaller than the nucleus of a lymphocyte associated with marked variation in size

(anisocytosis) and shape (poikilocytosis) (From Hillman et al.)

Figure 58-5

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Macrocytosis Red cells are larger than a small lymphocyte and well

hemoglobinized Often macrocytes are oval-shaped (macroovalocytes)

Figure 58-6

Figure 58-7

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Red cell changes in myelofibrosis The left panel shows a teardrop-shaped

cell The right panel shows a nucleated red cell These forms are seen in myelofibrosis with extramedullary hematopoiesis

Figure 58-8

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Target cells Target cells have a bull's-eye appearance and are seen in

thalassemia and in liver disease (From Hillman et al.)

Figure 58-9

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