Table 53-5 Common Skin Infections Clinical Features Etiologic Agent Treatmen t Impetigo Honey-colored crusted papules, plaques, or bullae Group A Streptococcus and Staphylococcus aur
Trang 1Chapter 053 Eczema and
Dermatitis (Part 10)
Ecthyma is a variant of impetigo that causes punched-out ulcerative lesions
It may result from neglected or inadequately treated impetigo Treatment of both ecthyma and impetigo involves gentle debridement of adherent crusts, which is facilitated by the use of soaks and topical antibiotics, in conjunction with
appropriate oral antibiotics Furunculosis is also caused by S aureus, and this
disorder has gained prominence in the last decade because of CA-MRSA A furuncle, or boil, is a painful, erythematous, nodule that can occur on any cutaneous surface The lesions may be solitary but are most often multiple Patients frequently believe they have been bitten by spiders or insects Family members or close contacts may also be affected Furuncles can rupture and drain spontaneously or may need incision and drainage, which may be adequate therapy
Trang 2for small solitary furuncles without cellulitis or systemic symptoms Whenever possible, lesional material should be sent for culture Current recommendations for methicillin-sensitive infections are β-lactam antibiotics Therapy for CA-MRSA was discussed previously (see "Atopic Dermatitis") Warm compresses and nasal mupirocin are helpful therapeutic additions Severe infections may require IV antibiotics
Table 53-5 Common Skin Infections
Clinical Features
Etiologic Agent
Treatmen
t
Impetigo Honey-colored
crusted papules, plaques, or bullae
Group A
Streptococcus and Staphylococcus aureus
Systemic
or topical antistaphylococc
al antibiotics
Dermatophytos
is
Inflammatory
or noninflammatory annular scaly plaques;
may have hair loss;
groin involvement
Trichophyto
n, Epidermophyton,
or Microsporum
Topical azoles, systemic griseofulvin, terbinafine, or
Trang 3spares scrotum;
hyphae on KOH preparation
Candidiasis Inflammatory
papules and plaques with satellite pustules, frequently in intertriginous areas;
may involve scrotum;
pseudohyphae on KOH preparation
Candida albicans and other Candida species
Topical nystatin or azoles; systemic azoles for resistant disease
Tinea
versicolor
Hyperpigment
ed or hypopigmented scaly patches on the trunk; characteristic mixture of hyphae and spores on KOH preparation
("spaghetti and
Malassezia furfur
Topical selenium sulfide lotion or azoles
Trang 4meatballs")
Erysipelas and Cellulitis
See Chap 119
Dermatophytosis
Dermatophytes are fungi that infect skin, hair, and nails and include
members of the genera Trichophyton, Microsporum, and Epidermophyton Tinea
corporis, or infection of the relatively hairless skin of the body (glabrous skin), may have a variable appearance depending on the extent of the associated inflammatory reaction (see Fig 52-11) Typical infections have an annular appearance that patients refer to as "ringworm." Deep inflammatory nodules or granulomas occur in some infections—especially in those infections inappropriately treated with mid- to high-potency topical glucocorticoids Involvement of the groin (tinea cruris) is more common in males than females It presents as a scaling, erythematous eruption sparing the scrotum Infection of the foot (tinea pedis) is the most common dermatophyte infection and is often chronic;
it is characterized by variable erythema, edema, scaling, pruritus, and occasionally vesiculation Involvement may be widespread or localized but generally involves the web space between the fourth and fifth toes Infection of the nails (tinea unguium or onychomycosis) occurs in many patients with tinea pedis and is
Trang 5characterized by opacified, thickened nails and subungual debris The distal-lateral variant is most common Proximal subungual onychomycosis may be a marker for HIV infection or other immunocompromised states Dermatophyte infection of the scalp (tinea capitis) has returned in epidemic proportions, particularly affecting
inner-city children, but it also affects adults The predominant organism is T tonsurans, which can produce a relatively noninflammatory infection with mild scale and hair loss that is diffuse or localized T tonsurans can also cause a
markedly inflammatory dermatosis with edema and nodules This latter presentation is a kerion
The diagnosis of tinea can be made from skin scrapings, nail scrapings, or hair by culture or direct microscopic examination with potassium hydroxide (KOH) Nail clippings may be sent for histologic examination with periodic acid Schiff (PAS) stain