Vevo_2100_Features_Overview_Ver1.2.Pdf

New and Improved Features• New Features – Faster frame rates – Multiple focal zones – Steerable Doppler – Advanced cardiac strain analysis package– Color Doppler Mode – ECG gated acquisi

Vevo ® 2100

Features

v1.2

New and Improved Features

• New Features

– Faster frame rates

– Multiple focal zones

– Steerable Doppler

– Advanced cardiac strain

analysis package– Color Doppler Mode

– ECG gated acquisition

– Large animal imaging:

rabbit

• Improved features

– Improved Power Doppler

Mode sensitivity– Faster 3D acquisition

– Software workflow

Vevo 770 Vevo 2100

Mechanical vs Linear Array

• 1 element

• 1 focal depth

• Lower frame rates, due to

the need to mechanically

scan

• 256 elements

• Dynamic focusing throughout the entire image

• Higher frame rates due to electronic switching of the elements

• Simultaneous modes

• Doppler Steering

Vevo 770: 707B – 30 Mhz

•Typical frame rate 100 fps

•Max frame rate (1 mm width) 240 fps

Vevo 2100: MS400 – 30 Mhz

•Typical frame rate 300 fps

•Frame rate 500 fps with 4.5 mm FOV

•Max frame rate (2 mm width) 1000 fps

Multiple & Dynamic Focal Zones

Video Loop

Multiple/Dynamic Focal Zones:

Sagittal Profile at E12

Video Loop

Multiple/Dynamic Focal Zones:

Midline Abdominal Landmarks

Color Doppler Mode Imaging

Video Loop

Color Doppler Mode:

Mitral Valve Inflow

Vevo 2100

Aortic Arch - Banding

Vevo 2100

Kovacs, Washington University

Advanced Strain Analysis

VevoStrain™ Software

Circumferential

Longitudinal Radial

Myocardial wall motion tracking

• Enables post-processing quantification of

myocardial wall abnormalities in

circumferential, radial and longitudinal axes

of heart motion

• Velocity • Displacement • Strain • Strain Rate

• All data quantification by point or region

ECG-Triggered Acquisition

Video Loop

ECG Gating: Systole/Diastole

Long Axis Systole Long Axis Diastole

Vevo 2100

3D of Heart with ECG Triggering

Other Array Benefits

Video Loop

Steerable Power and Color Doppler

Steered Power Doppler

in the Kidney

Steered Color Doppler

in the Femoral Artery Steered Pulse Wave Doppler

in the aorta

Video Loop

Simultaneous Scanning

(B-mode and PW Doppler)

Video Loop

Acquisition frame rate 27 fps Acquisition frame rate ~1-2 fps

Vevo770

Vevo 2100 Advantage – faster acquisition frame rate and greater sensitivity

Improved Power Doppler Imaging

Vevo 2100

Faster 3D Scanning

• Linear array

technology drastically reduces the amount

of time is takes to

acquire a 3D Power Doppler image

• 3D B-mode Imaging

~2x faster

• 3D Power Doppler

Imaging ~10x faster

Nonlinear Contrast Mode and VevoCQ™ Software

Video Loop

Image courtesy of Lazar J, SUNY Downstate Medical Center, 2010

Mouse subcutaneous hind limb model

User defined regions of interest

Curve fit algorithms

Vevo MicroMarker Quantification

Selection of VevoCQ bolus perfusion model parametric outputs

Parametric images

Perfusion Quantification

Whole Tumor (green) Bottom Right (yellow) Upper Area (pink) Bottom Left (turquoise)

VEGFR2 Isotype Control

Targeted Microbubble Ultrasound

Mouse subcutaneous hind limb model

User defined regions of interest

Curve fit algorithms

Targeted Biomarker Quantification

VevoCQ software differential targeted enhancement parametric output

Parametric images

Targeted Biomarker Quantification

Whole Tumor

(Green)

Left Area

(Yellow)

Right Area (Pink)

Transducer MS220:

For Larger Targets and Animals

Video Loop

15 MHz Transducer MS200:

Rabbit Heart

3kg Rabbit

Software Improvements

Study Management

Image of split screen

• Linear array probe

• Faster frame rate

• Multiple focal zones

• Nonlinear Contrast

• Steerable Doppler

• Advanced cardiac strain

analysis package

• Color Doppler Mode

• ECG gated acquisition

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