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Handbook of medicinal herbs phần 22

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Contraindications, Interactions, and Side Effects Black Bean — Not covered by AHP.. Contraindications, Interactions, and Side Effects Blackberry — Class 1 AHP.. Contraindications, Intera

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Activities (Black Bean) — Antiaggregant (1; FNF); Antiangiogenic (1; FNF); Antibacterial (1;

WBB); Anticancer (1; FNF); Antidepressant (1; FNF); Antidiabetic (1; PHR; PH2); Antileukemic

(1; FNF); Antilymphomic (1; FNF); Antimelanomic (1; FNF); Antiprostatitic (1; FNF); Antipyretic

(f; CRC); Antiviral (1; MPI); Apoptotic (1; FNF); Cardioprotective (1; FNF); Carminative (f; CRC;

EFS); Chemopreventive (1; FNF); Depurative (f; CRC; EFS); Diaphoretic (f; CRC); Diuretic (2;

PHR; KOM); Emmenagogue (f; CRC); Emollient (f; CRC; SKJ); Estrogenic (1; FNF; JAD);

Fungicide (1; CRC; DAA); Hepatoprotective (1; FNF); Hypocholesterolemic (1; FNF; JAD);

Hypoglycemic (1; DAA); Hypotensive (1; FNF); Lipolytic (1; FNF); Lipotropic (1; FNF);

Mutagenic (f; MPI); Resolvent (f; CRC; EFS)

Indications (Black Bean) — Acne (f; CRC); Albuminuria (f; CRC); Alcoholism (1; FNF); Anemia

(1; FNF); Anorexia (1; FNF); Anuria (2; KOM); Bacteria (1; WBB); Bladder Stone (2; PHR); BPH

(1; FNF); Burn (f; CRC); Cancer (1; FNF; JLH); Cancer, blood (1; DAA; FNF); Cancer, breast;

(1; FNF; JLH); Cancer, testicle (1; FNF; JLH); Cardiopathy (1; FNF); Cholecystosis (f; PHR);

Cold (f; CRC); Cystosis (1; CRC; MAD; PHR); Depression (1; FNF); Dermatosis (f; FNF); Diabetes

(1; CRC; DAA; FNF; MAD; PHR; PH2); Diarrhea (f; CRC); Dropsy (f; CRC; MAD); Dysentery

(f; CRC); Dysuria (1; PHR); Eczema (f; CRC); Edema (f; FNF); Endometriosis (1; FNF; TGP);

Enterosis (1; FNF); ERT (1; FNF); Fever (f; CRC); Fibrosis (f; FNF); Fungus (1; CRC; DAA);

Gas (f; CRC; EFS); Gastrosis (f; FNF); Glaucoma (1; FNF); Gout (f; MAD); Headache (f; CRC);

Heart (f; CRC); Hematuria (f; MAD); Hepatosis (1; FNF); Hiccup (f; CRC); High Blood Pressure

(1; FNF); High Cholesterol (1; FNF; JAD); Hot Flashes (1; FNF); Hyperglycemia (1; DAA);

Hyperlipoproteinemia (1; FNF); Infection (1; CRC; DAA; PHR; PH2; WBB); Itch (f; CRC); Kidney

Stone (2; PHR); Leukemia (1; FNF); Lymphoma (1; FNF); Melanoma (1; FNF); Menopause (1;

FNF; JAD); Mycosis (1; CRC; DAA); Nephrosis (f; CRC; DAA; FNF; PHR); Neurosis (f; FNF);

Obesity (1; FNF); Osteoporosis (1; FNF; JAD); Pain (f; JLH); Pericardosis (f; MAD); Pleurosis

(f; MAD); Retinosis (1; FNF); Rheumatism (f; CRC; DAD; MAD); Rickets (f; FNF); Sciatica (f;

CRC; DAA); Scurvy (f; CRC); Sore (f; FNF; JLH); Steatosis (f; FNF); Stone (2; PHR; PH2);

Syndrome-X (1; FNF; SYN); Tenesmus (f; CRC); Toxemia (f; FNF); Tuberculosis (f; FNF); Tumor

(f; CRC; JLH); Ulcer (f; JLH); UTI (2; PHR); Virus (1; MPI); Wart (f; CRC); Water Retention (2;

KOM; MAD; PHR)

Dosages (Black Bean) — Drink the string bean pot likker as food farmacy, and eat the string beans

(JAD); I often enjoy 100–200 g with diced raw onion; 0.5 cup seed (100 g) as food (JAD); 5–15

g herb (green pod)/day (KOM; PHR); pour hot water over 2.5 g dry powdered pods

Contraindications, Interactions, and Side Effects (Black Bean) — Not covered by AHP.

None known (KOM).“Hazards and/or side effects not known for proper therapeutic dosages”

(PH2) The Herbal PDR hints that poisonings due to over consumption of too many raw beans

is not impossible, due to lectins, which are destroyed by cooking Symptoms include diarrhea,

gastroenterosis, and vomiting Of course, overconsumption of dry bean seeds can also lead to

GI distress such as flatus and dyspepsia

BLACKBERRY (Rubus spp.) ++

Most European entries (EFS, HHB, MAD, PH2) accrue to R fruticosus, the European blackberry.

Most American entries (CEB, DEM, FAD, FEL) accrue to American species I think raspberries

and blackberries can be treated generically, when it comes to medicine, like bilberries and

blueberries

Activities (Blackberry) — Antibacterial (1; MAD); Antidote (f; DEM); Antiinflammatory (1;

APA); Antioxidant (1; JNU); Antitumor (f; APA); Apoptotic (f; JNU); Astringent (1; APA; EFS

PH2); Depurative (f; DEM; EFS); Detoxicant (1; JNU); Diaphoretic (f; MAD); Diuretic (f; DEM;

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EFS); Fungicide (f; MAD); Hemostat (1; APA); Hypocholesterolemic (1; JNU); Stimulant (f; DEM); Tonic (f; DEM; EFS)

Indications (Blackberry) — Angina (f; MAD); Appendicitis (f; MAD); Bacteria (1; MAD);

Bleeding (1; APA; DEM; FEL; FNF; MAD); Boil (1; DEM; FNF); Bronchosis (f; CEB; MAD); Cancer (1; JLH; JNU); Catarrh (f; DEM); Childbirth (f; FEL); Cholera (f; FEL); Cold (f; DEM; MAD); Condyloma (f; JLH); Conjunctivosis (1; CEB; DEM; FNF); Cough (f; CEB; DEM; MAD); Dermatosis (f; MAD); Diabetes (f; MAD); Diarrhea (2; APA; DEM; PHR; PH2); Dropsy (f; APA; MAD; PH2); Dysentery (1; DEM; FNF); Dysmenorrhea (f; DEM; MAD); Dysuria (f; DEM); Enterosis (1; APA; MAD; PH2); Exanthema (f; MAD); Fever (f; DEM; FEL; MAD); Fungus (1; MAD); Gastrosis (1; APA; DEM; PH2); Gleet (f; FEL); Glossosis (f; DEM); Gonorrhea (f; FEL); Gout (f; APA); Gravel (f; CEB); Headache (f; DEM); Hemate-mesis (1; DEM; FNF); Hemoptysis (f; CEB); Hemorrhoid (1; APA; CEB; DEM); High Cho-lesterol (1; JNU); Infection (1; DEM; FNF; MAD); Inflammation (1; APA; JLH); Leukorrhea (f; FEL; MAD); Lung Problem (f; DEM); Menorrhagia (f; MAD); Miscarriage (f; DEM); Mycosis (1; MAD); Nausea (f; FEL); Nephrosis (f; MAD); Ophthalmia (f; CEB; DEM); Pharyngosis (2; APA; PHR; PH2); Phthisis (f; CEB); Proctosis (f; FEL); Prolapse (f; FEL); Pulmonosis (f; CEB); Rheumatism (f; DEM); Scab (f; MAD); Scabies (f; MAD); Sore (1; DEM; FNF); Sore Throat (2; APA; DEM); Stomatosis (2; APA; MAD; PHR; PH2); Stone (f; MAD); Swelling (f; APA); Tonsilosis (f; MAD); Tuberculosis (1; DEM; FNF; MAD); Tumor (f; APA); Uterosis (f; FEL); VD (f; DEM); Vomiting (f; DEM; FEL); Wart (f; JLH); Water Retention (f; DEM; EFS); Wound (f; APA)

Dosages (Blackberry) — 1–2 tsp chopped leaf/cup water, up to 6 ×/day; 4 tsp (~4.4 g) leaf in hot tea; 1.5 g leaf/cup tea, 2–3 ×/day (PH2); 1–2 tsp powdered bark/cup water; up to 2 tsp tincture/day (APA); 1500 mg root tea up to 3 ×/day (APA); 20–30 grains powdered root bark (FEL); 2–4 ml liquid root extract (PNC)

Contraindications, Interactions, and Side Effects (Blackberry) — Class 1 (AHP).

Extracts (Blackberry) — Anthocyanins and polyphenols in berries of several Ribes, Rubus, and

Vaccinium spp have in vitro antiradical activity on chemically generated superoxide radicals The

extracts also inhibit xanthine oxidase All crude extracts were highly active toward chemically

generated superoxide radicals Ribes nigrum extracts exhibited most activity, being the richest in both anthocyanins and polyphenols But Ribes rubrum extracts seem to contain more active

sub-stances (X1332092)

BLACKBERRY LILY (Belamcanda chinensis (L.) DC.) ++

Synonym — B punctata Moench, Gemmingia chinensis Kuntze, Ixia chinensis L.

Activities (Blackberry Lily) — Alexeteric (f; WO2); Antiallergic (1; WO3); Antiasthmatic

(f; WO3); Antibacterial (1; FAY); Antidote, curare (f; FAY); Antiemetic (f; LMP); Antihista-minic (f; WO3); Antiinflammatory (f; WO3); Antioxidant (1; WO3); Antipyretic (f; DAA); Antitussive (f; WO3); Antiviral (1; FAY); Aperient (f; WO2); Bitter (f; LMP; WO2); Carmi-native (f; LMP); Cholinergic (1; WO3); Deobstruent (f; LMP; WO2); Depurative (f; LMP; WO2); Detoxicant (f; FAY); Diuretic (f; LMP); Emmenagogue (f; LMP); Expectorant (f; DAA; FAY; WO3); Fungicide (1; FAY); Hypotensive (1; FAY); Laxative (f; DAA); Stomachic (f; DAA); Tonic (f; DAA)

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Indications (Blackberry Lily) — Allergy (1; WO3); Asthma (1; DAA; LMP; WO3); Bacteria (1;

FAY); Boil (f; DAA); Bronchosis (f; FAY); Bruise (f; DAA); Cancer (f; DAA); Cancer, breast (f;

DAA; FAY); Cancer, larynx (f; DAA); Childbirth (f; LMP); Constipation (f; DAA); Cough (f;

FAY); Dermatosis (f; FAY); Dropsy (f; DAA); Dysmenorrhea (f; DAA; FAY); Dysuria (f; DAA);

Fever (f; DAA); Fungus (1; FAY); Gas (f; LMP); Gastrosis (f; DAA); Goiter (f; DAA); Gonorrhea

(f; DAA; LMP); Hepatosis (f; DAA; FAY); High Blood Pressure (1; FAY); Infection (1; FAY);

Inflammation (f; WO3); Laryngosis (f; DAA; FAY); Lumbago (f; LMP); Malaria (f; DAA); Mastosis

(f; DAA; FAY); Mycosis (1; FAY); Parotosis (f; FAY); Pulmonosis (f; DAA); Rheumatism (f;

DAA); Sore Throat (f; FAY; WO3); Splenosis (f; DAA; FAY); Stomachache (f; DAA); Swelling

(f; DAA; LMP); Tonsilosis (f; DAA; FAY; LMP); VD (f; DAA); Virus (1; FAY); Vomiting (f; LMP);

Water Retention (f; LMP)

Dosages (Blackberry Lily) — 2.5–9 g root in decoction (FAY); root made into poultice (FAY).

Contraindications, Interactions, and Side Effects (Blackberry Lily) — Not covered (AHP;

KOM; PH2) Contraindicated in pregnancy; contains toxic iridoids belamcandin and iridin Root

for use only under medical supervision

BLACK BRYONY (Tamus communis L.) X

Activities (Black Bryony) — Allergenic (1; PH2); Diuretic (f; GMH); Emetic (1; GMH; PH2);

Histaminic (1; PH2); Laxative (f; EFS; HHB); Propecic (f; HHB; PH2); Rubefacient (f; PH2);

Toxic (1; GMH); Vulnerary (f; EFS)

Indications (Black Bryony) — Alopecia (f; HHB; PH2); Arthrosis (f; JLH); Asthma (f; GMH);

Bruise (f; EFS; PH2); Cancer (f; JLH); Cancer, spleen (f; JLH); Chilblain (f; GMH);

Consti-pation (f; HHB); Dermatosis (f; PH2); Gout (f; PH2); Gravel (f; GMH); Induration (f; JLH);

Paralysis (f; GMH); Phymata (f; JLH); Polyp (f; JLH); Rheumatism (f; PH2); Rhinosis (f;

JLH); Sore (f; GMH); Splenosis (f; JLH); Strain (f; PH2); Water Retention (f; GMH); Whitlow

(f; JLH)

Dosages (Black Bryony) — Don’t take internally (JAD) Fruits steeped in gin for chilblain

(GMH)

Contraindications, Interactions, and Side Effects (Black Bryony) — Not covered (AHP;

KOM) Oxalate needles on contact may trigger histaminic reactions; internally may irritate

mouth, throat, stomach, and intestines (PH2) “Death in most painful form is the result of an

overdose” (GMH)

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BLACK COHOSH (Actaea racemosa L.) +

Synonym — Cimicifuga racemosa (L.) Nutt.

Activities (Black Cohosh) — Abortifacient (f; DEM); Alterative (f; CRC; PED); Analgesic (f;

DEM); Antibacterial (f; APA); Antidotal (f; CRC); Antiinflammatory (f; CRC; PNC); Antipyretic (1; PNC); Antirheumatic (1; MAB; PED); Antiserotonin (1; MAB); Antispasmodic (1; MAB; PED; PNC); Antitumor-Proliferation (1; MAB); Antitussive (f; CAN; CRC); Antiulcer (1; PNC); Aph-rodisiac (f; CRC); Astringent (1; CRC; DEM; PED); Bitter (1; HHB; PED); CNS-Depressant (1; PNC); Depurative (f; DEM); Diaphoretic (f; CRC; PED); Diuretic (f; APA; PED; PNC); Emmen-agogue (1; CRC; PED; PNC); Estrogenic (2; KOM; MAB; PED; PH2); Expectorant (f; APA; CRC; PED); Hypoglycemic (1; APA; CRC; PNC); Hypotensive (1; APA; MAB; PNC); Immunodepressant (1; MAB); Lactagogue (f; DEM); Mucolytic (f; APA); Narcotic (f; CRC); Peripheral Vasodilator (2; CAN; CRC; PNC); Sedative (1; FAD; CAN; CRC); Stomachic (f; CRC); Luteinizing-Hormone Suppressant (2; APA; KOM); Tonic (f; CRC; DEM; HHB); Tranquilizer (f; APA); Uterocontractant (1; PED); Uterotonic (1; MAB)

Indications (Black Cohosh) — Adenopathy (f; JLH); Amenorrhea (1; CRC; MAB); Arthrosis (f;

CAN; CRC; HHB); Asthma (f; MAB); Autoimmune Disease (1; MAB); Backache (f; DEM); Bacteria (f; APA); Bite (f; PH2); Bronchosis (f; APA; CRC; FAD; PED; PH2); Cancer (1; JLH; MAB); Cancer, groin (f; JLH); Cancer, liver (f; CRC); Cancer, tongue (f; JLH); Chorea (f; CAN; CRC; FAD; HHB; MAB); Neurovegetative Ailment (2; HHB; KOM); Cold (f; DEM); Constipation (f; DEM); Cough (f; APA; CAN; DEM); Cramp (1; MAB; PED; PNC; SKY); Diabetes (1; APA;

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PNC); Diarrhea (1; CRC; DEM; PED); Dropsy (f; CRC); Dysmenorrhea (2; APA; HHB; KOM;

PH2; SKY); Dyspepsia (f; APA); ERT (2; KOM; MAB; PED); Fatigue (f; DEM); Fever (1; CRC;

FAD; PED; PH2; PNC); Gynecopathy (f; CRC); High Blood Pressure (1; APA; MAB; PNC); Hives

(f; DEM); Hot Flash (1; APA); HRT (2; BGB); Hyperglycemia (1; APA; CRC; PNC); Hysteria (f;

CRC); Inflammation (f; CRC; PNC); Insomnia (1; CAN; CRC; DEM; FAD; PNC); Itch (f; CRC);

Lumbago (1; CRC; FAD; PH2); Malaise (f; BGB; CRC); Malaria (f; BGB; CRC); Mastosis (1;

MAB); Measles (f; PH2); Menopause (2; BGB; MAB; PH2 SHT); Menorrhagia (1; CRC; MAB);

Menstrual Problem (2; SKY); Metastasis (f; JLH); Myalgia (f; CAN); Nephrosis (f; BGB; CRC;

DEM); Nervousness (1; APA; FAD; CAN; CRC); Neuralgia (f; MAB); Nervousness (1; APA;

CRC); Otosis (f; HHB); Pain (f; BGB; DEM; HHB); Parturition (1; CRC; FAD); Pertussis (f; CRC;

MAB; PNC); PMS (2; APA; KOM; PH2); Poor Milk Supply (f; DEM); Rheumatism (1; APA;

BGB; CAN; HHB; MAB; PED; PH2); Sciatica (1; CAN); Scirrhus (f; JLH); Snakebite (f; APA;

CRC; FAD; PH2); Sore Throat (f; APA; BGB; CRC; PH2); Tinnitus (1; CAN; CRC; MAB);

Tuberculosis (f; DEM); Tumor (1; MAB); Ulcer (1; PNC); Uterosis (f; CRC); Water Retention (f;

APA; PED; PNC); Yellow Fever (f; CRC)

Dosages (Black Cohosh) — 40–200 mg/day (APA); 0.5 tsp powdered root/cup water, up to 1 cup/day

(APA); 1 g powdered root 3 ×/day (HHB); 0.3–2 g powdered root (PNC); 0.5–1 g dry root 3–4 ×/day

(MAB); 1.5–3 g dry root (PED); 300–2000 mg dry root (SF); 2 g dry root:10 ml alcohol/10 mg water

(PED); 1–3 tbsp fresh root (PED); 0.3–2 g rhizome 3 ×/day (CAN; SKY); 0.3–2 ml liquid root extract

(PNC); 2–4 ml root tincture; 40 mg herb in 40–60% ethanol (SF); up to 1 tsp tincture/day (APA);

2–4 ml tincture (1:10 in 60% alcohol) (CAN); 3.5–7 ml tincture (1:5); 6–12 ml tincture (1:10) (MAB);

0.3–2.0 ml liquid extract (1:1 in 90% alcohol) (CAN); 1.5–3 ml fluid extract (1:2) (MAB); 1 (540

mg) capsule 3 ×/day (NH); 40 mg StX (1 mg deoxyacteine)/day (SKY)

Contraindications, Interactions, and Side Effects (Black Cohosh) — Class 2b, 2c (AHP) No

contraindications/drug interactions noted (KOM) I got a challenging letter from German parties

with an economic interest in cohosh, asking where I got the cautionary remarks from in my 1985

CRC book They must really be irritated by what follows: Commission E reports occasional gastric

complaints Not to be used for more than 6 months (AEH) With prolonged use, may irritate the

uterus, cause dizziness, diarrhea, nausea, vomiting, abdominal pain, headaches, joint pains, and

lowered heart rate Can contribute to abnormal blood clotting and liver problems Can encourage

breast tumors Should not be used by anyone with any type of heart disease or by anyone advised

not to take oral contraceptives “Women taking estrogen therapy should consult a physician before

using black cohosh” (SKY) Can cause premature labor Because of insufficient data, use during

pregnancy and lactation is not advised Should be used only under medical supervision (TMA,

1996) High doses may cause diaphoresis, dizziness, nausea, reduced pulse rate, visual disturbances,

and vomiting (CAN) Because of uterine estrogen receptor binding in vitro, its use in pregnancy

and lactation is to be avoided What they say about black cohosh should be templated and said for

every herb, “It has been recommended that black cohosh should only be used in therapeutic doses,

and that high doses are potentially dangerous” (CAN) “Canadian regulations do not allow black

cohosh as a non-medicinal ingredient for oral use products” (Michols, 1995) Pedersen is not much

kinder, “Such constituents as tannins, gallic acid, and pseudotannins, including isoferulic acid, and

the salicylates, are irritants to the skin, lungs, and kidneys The drastic action of the irritant principles

in black cohosh are not lethal, but overdoses are characterized by nausea and headache” (PED)

Schulz et al (1998) are nicer to this herb, sold in Germany and America, than the Anglos quoted

above In five studies using doses equivalent to 40 mg/day crude herb, there are no case reports of

toxic effects from the herb, and there appears to be no specific toxicity associated with any of its

known constituents Two of the five showed mild side effects (dizziness, GI distress, headache, and

weight gain) No other contraindications are known The duration of use should not exceed 3 months

(SHT) Cohosh extract augmented the activity of tamoxiphen (MAB) Finally, let me quote

Gruen-wald, editor-in-chief of the Herbal PDR, and coincidentally, also editor of the ABC Commission

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