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Goal 3: Influencing Research PCORI is credited with inspiring policy changes and capacity building efforts at the University of Arkansas for Medical Science UAMS, including an IRB Dissem

Trang 1

Dashboard Review

Fourth Quarter of FY-2017

Joe Selby, MD, MPH

Executive Director

Trang 2

0 25 50 75 100

Time to Complete Peer Review (Target: 4 months)

0 25 50 75 100

% Abstracts Posted to PCORI.org in < 90 days

1

3

0 2 4 6 8 10

Funds Committed to Research Project Performance

Draft Final Research Reports

External Funding in PCORnet

Budget

50 60 70 80 90 100

% of Projects On Track

Board of Governors Dashboard

On Target Off Target

Q4 2017 Q3 2017 Q2 2017 Q1 2017

$ Millions

Projected/Target

5

8

12 9

0

10

20

30

40

50

60

70

Other CER

Budgeted $428M for FY-2017

Public Reporting of Research Findings

Actual

Results Published in Literature Altmetrics

Number of Publications in Top 5% of Research Scored

Target

> 90%

Q1 Q2 Q3 Q4 0 100 200 300 400

$ Millions

Budgeted $423M for FY-2017

Actual

2

6

3

5

0 5 10 15 20

Externally- and Co-Funded Projects (Cumulative)

Goal 2:

Speeding Uptake

PCORI-funded results on self-monitoring of blood glucose have been taken up into practice via UpToDate®, a point-of-care, evidence-based medical resource software used by clinicians globally, and nearly 90% of major academic medical centers in the US

Goal 3:

Influencing Research

PCORI is credited with inspiring policy changes and capacity building efforts at the University of Arkansas for Medical Science (UAMS), including an IRB

Dissemination policy on returning results to the

Narrative Examples

Goal 1:

Increasing Information

A PCORI-funded study comparing two programs to prevent falls among older adults found that a group-based standing-exercise program called On The Move

is more effective than commonly used seated exercises

Operating Budget and Research Awards

0

25

50

75

100

% of Draft Final Research

Reports On Time

Target

> 90%

Target

100 %

Q1-Q2: NA

Too Early to Evaluate / No Target

Includes funds committed to PCORnet

36 36

19

23

N= 27 29

Q1 Q2 Q3 Q4 Q2 Q3 Q4

0 33

Q3 Q4

N=1

PCORI Peer Review

Target

> 90%

0 21

Completed as of Q4: 12

Median time: 9.2 months

Other

CER

Co-Funded with PCORI

Externally Funded

29

Total FY-17

$379M

Trang 3

Goal 1: Results of PCORI-Funded Research

Standing-exercise is more effective than seated exercise in improving mobility in older adults

” Older adults who are interested in improving their

mobility should consider participating in a group-based

T designed to be more challenging for participants, but they are important for walking and can improve mobility.

-Dr Jennifer Brach, Study Investigator

Consumer.HealthDay.com article

• Principal Investigator: Jennifer S Brach, PhD,

University of Pittsburgh at Pittsburgh

Brach JS, Perera S, Gilmore S, et al Effectiveness of a Timing and Coordination Group Exercise Program to

Improve Mobility in Community-Dwelling Older Adults: A Randomized Clinical Trial Jama Internal Aug 2017.

Study title: On the Move: Optimizing Participation in Group Exercise to Prevent Walking

Difficulty in At-Risk Older Adults

Exercise is beneficial to physical and mental health and may prevent walking difficulty

and promote independence for community-dwelling older adults Exercise programs

offered to older adults are typically a seated range-of-motion exercises that do not

involve walking

This study compared the effectiveness of an exercise program (On the Move) that

focuses on the timing and coordination of movement with usual care (a seated strength,

endurance, and flexibility program) The study found that the On the Move program

was more effective than the seated exercise program at improving function, disability,

and walking ability of older adults.

Trang 4

Recent results from a PCORI-funded study on self-monitoring of blood glucose (SMBG) have been taken up in UpToDate ® , a point-of-care, evidence-based

medical resource software used by more than 1.3 million clinicians in 187

countries, including nearly 90% of major academic medical centers in the United States 1

At least 4 CER results publications from PCORI-funded studies have now been taken up in UpToDate®

Goal 2: Speed Uptake and Use of Information

Topic page titled: Self-monitoring of blood glucose in management of adults

o Young LA, et al Glucose Self-monitoring in Non Insulin-Treated Patients With Type 2 Diabetes in

Primary Care Settings: A Randomized Trial JAMA Internal June 2017

PI: Katrina Donahue, MD, MPH, University of North Carolina at Chapel Hill

1UpToDate About Us UpToDate®, Inc 2017 https://www.uptodate.com/home/about-us

2McCulloch, DK Self-monitoring of blood glucose in management of adults with diabetes mellitus In: UpToDate®, Hirsch, IB (ed), UpToDate®, Waltham, MA, 2017

Trang 5

A PCORI-funded project (PI: Peter Kohler, MD, University of Arkansas for

Medical Sciences) has inspired policy changes and capacity building efforts at

the University of Arkansas for Medical Science (UAMS)

Policy changes:

coordinators, interpreters, and community health workers representing the communities of research focus

(implementation in progress)

Capacity building:

Implementation of a training on the responsible conduct of research for non-academic

research partners

Bolstered services offered through Community Engagement component of the UAMS

Translational Research Institute to mentor ~25 UAMS researchers

Goal 3: Influencing Research Example:

Establishment of Policies and Programs to Promote PCOR

[Peter Kohler, MD & Pearl McElfish, Ph.D; July 2017]

Trang 6

2012 2013 2014 2015 2016 2017 2018

0

500

1000

1500

2000

2500

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

Cumulative Funds Committed to Research and Research I nfrastructure

$1.95B Committed to Research through FY-2017

$683M

End FY-14

$1.2B

End FY-15

$1.6B

End FY-16

$2.39B

Budgeted End FY-18

$333M

End FY-14

$1.95B

End FY-17

Trang 7

Assessment of Prevention, Diagnosis, and Treatment Options, $672M, 34%

Improving Healthcare Systems, $451M, 23%

Communication and Dissemination Research,

$109M, 6%

Addressing Disparities,

$235M, 12%

Research and Research Infrastructure Commitments by National Priority

as of 9/30/2017

Cumulative Research & Research Infrastructure Funding

Commitments by National Priority for Research as of FY-2017

$1.948B

Subset: PCORnet Infrastructure and

Workforce Training, $355M, 18%

Subset: Methods Research, $125M, 6%

Accelerating Patient-Centered Research and Methodological Research, $480M, 25%

Trang 8

We are making progress on our Strategic Priority to “ Increase the

proportion of research funding going to focused and targeted topics”

$244

$440 $555

$669 $746

$50

$108

$186

$321

$483

$179

$258

$332

17%

20%

40%

46%

52%

0%

10%

20%

30%

40%

50%

60%

0

250

500

750

1,000

1,250

1,500

1,750

2,000

Cumulative

as of FY-2013

Cumulative

as of FY-2014

Cumulative

as of FY-2015

Cumulative

as of FY-2016

Cumulative

as of FY-2017

Cumulative Funds Committed to Research

by Fiscal Year

Broad Targeted Pragmatic

% of Funding to Focused/Targeted Research

Trang 9

Status of PCORI-Funded Research Projects

*Does not include Pilots, Infrastructure, or D&I awards

*Does not include studies awarded in Q1-2018

311

3

123

0

50

100

150

200

250

300

350

Awarded;

Contract

Pending

Active;

Too early for quarterly project evaluation

Active;

Eligible for quarterly project evaluation

Active;

DFRR due and not yet submitted

Active;

In PCORI Peer Review (during all of Q4)

Complete;

Summaries being developed for posting

Complete;

Results posted

to PCORI.org

Terminated

Status of PCORI-Funded Research Projects

N=496, as of Q4-17 A refers to the PCORI

contract period, which includes both the research period and PCORI Peer Review

Trang 10

67

72 73 74

78 78 79 79 77

21

25

22

20 21

18

16 16 17 17

9 9

6 7 5

4 6 5 5 7

0

10

20

30

40

50

60

70

80

90

Q3-15 Q4-15 Q1-16 Q2-16 Q3-16 Q4-16 Q1-17 Q2-17 Q3-17 Q4-17

Green Zone

Yellow Zone

Off Track (Orange/Red) Award

Terminated*

Project Status by Color Zones

Q3-15 to Q4-17

We are monitoring trends and shifts in project status

*Notice of Termination Issued,

Trang 11

2016 2017 2018

13

21

29

36

38

33

21

13

21

29

36

29

7

2

0

10

20

30

40

50

Draft Final Research Reports (DFRRs)

Including those turned in early or late DFRRs Due DFRRs Turned In

Draft Final Research Reports Submitted

Trends Over Time

This figure shows that many DFRRs due in early 2018 have already

been turned in

Trang 12

PCORI Peer Review Process and Public Release of Findings

We expect 40-50 studies

to be completed by end of Q1-18 (Dec 31st)

33

In Process:

Undergoing PCORI Peer Review

67

In Process;

Final edits underway

9

PCORI Peer Review Complete;

Summaries being developed

3

Results Posted;

PCORI Peer-Reviewed results posted to PCORI.org

Studies in PCORI Peer Review Process

or Completed PCORI Peer Review

N=135, as of Q4-17

23

In Process:

Pre-Review Edits

Underway

Trang 13

1

29

46 203

14

45

124 210

16

47

176 300

145

0 50

100

150

200

250

300

350

All Articles Resulting from PCORI-funded Projects

CER Results Publications from PCORI-funded Projects

Articles by or about

PCORI

Articles that Cite or Mention PCORI Work

Journal

Articles

Journal Publications by Year

Journal Publications Related to PCORI and PCORI-funded Projects

Trang 14

0 25 50 75 100

Time to Complete Peer Review (Target: 4 months)

0 25 50 75 100

% Abstracts Posted to PCORI.org in < 90 days

1

3

0 2 4 6 8 10

Funds Committed to Research Project Performance

Draft Final Research Reports

External Funding in PCORnet

Budget

50 60 70 80 90 100

% of Projects On Track

Board of Governors Dashboard

On Target Off Target

Q4 2017 Q3 2017 Q2 2017 Q1 2017

$ Millions

Projected/Target

5

8

12 9

0

10

20

30

40

50

60

70

Other CER

Budgeted $428M for FY-2017

Public Reporting of Research Findings

Actual

Results Published in Literature Altmetrics

Number of Publications in Top 5% of Research Scored

Target

> 90%

Q1 Q2 Q3 Q4 0 100 200 300 400

$ Millions

Budgeted $423M for FY-2017

Actual

2

6

3

5

0 5 10 15 20

Externally- and Co-Funded Projects (Cumulative)

Goal 2:

Speeding Uptake

PCORI-funded results on self-monitoring of blood glucose have been taken up into practice via UpToDate®, a point-of-care, evidence-based medical resource software used by clinicians globally, and nearly 90% of major academic medical centers in the US

Goal 3:

Influencing Research

PCORI is credited with inspiring policy changes and capacity building efforts at the University of Arkansas for Medical Science (UAMS), including an IRB

Dissemination policy on returning results to the

Narrative Examples

Goal 1:

Increasing Information

A PCORI-funded study comparing two programs to prevent falls among older adults found that a group-based standing-exercise program called On The Move

is more effective than commonly used seated exercises

Operating Budget and Research Awards

0

25

50

75

100

% of Draft Final Research

Reports On Time

Target

> 90%

Target

100 %

Q1-Q2: NA

Too Early to Evaluate / No Target

Includes funds committed to PCORnet

36 36

19

23

N= 27 29

Q1 Q2 Q3 Q4 Q2 Q3 Q4

0 33

Q3 Q4

N=1

PCORI Peer Review

Target

> 90%

0 21

Completed as of Q4: 12

Median time: 9.2 months

Other

CER

Co-Funded with PCORI

Externally Funded

29

Total FY-17

$379M

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