III. ABSTRACTS AND POSTERS / ORAL PRESENTATIONS
6. Mice deficient in interferon regulatory factor 4 (IRF4) are more susceptible to infection with mouse-adapted influenza A/Aichi/2/68
8.8 Statistical Analysis of fold changes in lung homogenate cytokine concentrations measured by multiplex cytokine assay
G-CSF
Descriptivesa Fold Change
13 113.51701 211.621876 58.693348 -14.36481 241.39883 17.161 809.238 13 81.73654 68.809139 19.084222 40.15559 123.31749 25.857 290.382 13 101.19786 69.655883 19.319066 59.10524 143.29049 26.193 198.324 39 98.81714 131.701518 21.089121 56.12445 141.50983 17.161 809.238 -/-
+/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = G-CSF a.
ANOVAa Fold Change
6675.513 2 3337.757 .184 .833
652445.5 36 18123.486
659121.0 38
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = G-CSF a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
31.780474 52.803680 1.000 -100.81170 164.37265 12.319150 52.803680 1.000 -120.27302 144.91132 -31.780474 52.803680 1.000 -164.37265 100.81170 -19.461324 52.803680 1.000 -152.05350 113.13085 -12.319150 52.803680 1.000 -144.91132 120.27302 19.461324 52.803680 1.000 -113.13085 152.05350 (J) genoty pe
+/- +/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/- +/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
group = G-CSF a.
299 GM-CSF
Descriptivesa Fold Change
14 7.17439 2.858574 .763986 5.52390 8.82488 2.775 12.553
13 2.20824 .863141 .239392 1.68665 2.72983 1.242 4.343
14 2.75709 1.507686 .402946 1.88657 3.62760 .842 6.189
41 4.09141 2.953027 .461185 3.15932 5.02350 .842 12.553
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = GM-CSF a.
ANOVAa Fold Change
204.095 2 102.048 26.795 .000
144.720 38 3.808
348.815 40
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = GM-CSF a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
4.966154* .751654 .000 3.08355 6.84876
4.417305* .737603 .000 2.56989 6.26472
-4.966154* .751654 .000 -6.84876 -3.08355
-.548849 .751654 1.000 -2.43145 1.33375
-4.417305* .737603 .000 -6.26472 -2.56989
.548849 .751654 1.000 -1.33375 2.43145
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = GM-CSF a.
300 IFN-gamma
Descriptivesa Fold Change
13 7.71162 8.108790 2.248974 2.81153 12.61171 2.126 32.475
12 19.58692 21.959014 6.339021 5.63483 33.53902 5.040 85.125
12 45.08713 35.704951 10.307132 22.40129 67.77298 15.071 134.594 37 23.68486 28.446623 4.676596 14.20028 33.16943 2.126 134.594 -/-
+/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IFN-gamma a.
ANOVAa Fold Change
9015.082 2 4507.541 7.618 .002
20116.490 34 591.661
29131.572 36
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IFN-gamma a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
-11.875307 9.737430 .693 -36.39668 12.64607
-37.375515* 9.737430 .002 -61.89689 -12.85414
11.875307 9.737430 .693 -12.64607 36.39668
-25.500208* 9.930269 .044 -50.50720 -.49322
37.375515* 9.737430 .002 12.85414 61.89689
25.500208* 9.930269 .044 .49322 50.50720
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/- +/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = IFN-gamma a.
301 IL-10
Descriptivesa Fold Change
14 14.38794 12.356027 3.302287 7.25378 21.52210 1.386 46.980
14 6.67941 2.496145 .667123 5.23818 8.12064 1.246 11.702
8 5.07771 1.528971 .540573 3.79946 6.35596 2.827 6.976
36 9.32124 8.755835 1.459306 6.35869 12.28379 1.246 46.980
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-10 a.
ANOVAa Fold Change
601.170 2 300.585 4.764 .015
2082.092 33 63.094
2683.263 35
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-10 a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
7.708530* 3.002230 .045 .13627 15.28079
9.310232* 3.520427 .037 .43097 18.18950
-7.708530* 3.002230 .045 -15.28079 -.13627
1.601702 3.520427 1.000 -7.27756 10.48097
-9.310232* 3.520427 .037 -18.18950 -.43097
-1.601702 3.520427 1.000 -10.48097 7.27756
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = IL-10 a.
302 IL-12 p40
Descriptivesa Fold Change
1 .11241 . . . . .112 .112
3 1.23077 .477843 .275883 .04374 2.41780 .690 1.597
2 1.29589 .046330 .032761 .87963 1.71215 1.263 1.329
6 1.06608 .557726 .227691 .48079 1.65138 .112 1.597
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-12 p40 a.
ANOVAa Fold Change
1.096 2 .548 3.585 .160
.459 3 .153
1.555 5
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-12 p40 a.
303 IL-12 p70
Descriptivesa Fold Change
10 2.38134 2.066481 .653479 .90307 3.85962 .061 5.653
7 .95809 .174903 .066107 .79633 1.11985 .604 1.105
11 1.09752 .078951 .023805 1.04449 1.15056 .941 1.190
28 1.52117 1.364519 .257870 .99207 2.05028 .061 5.653
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-12 p70 a.
ANOVAa Fold Change
11.593 2 5.796 3.746 .038
38.679 25 1.547
50.272 27
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-12 p70 a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
1.423255 .612975 .086 -.14963 2.99614
1.283819 .543477 .079 -.11073 2.67837
-1.423255 .612975 .086 -2.99614 .14963
-.139436 .601393 1.000 -1.68260 1.40373
-1.283819 .543477 .079 -2.67837 .11073
.139436 .601393 1.000 -1.40373 1.68260
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/- +/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
group = IL-12 p70 a.
304 IL-13
Descriptivesa Fold Change
12 1.51823 .553184 .159690 1.16676 1.86971 .888 2.665
12 .74440 1.310256 .378238 -.08810 1.57689 .011 3.654
12 1.03639 1.237607 .357266 .25005 1.82272 .005 3.807
36 1.09967 1.105364 .184227 .72567 1.47367 .005 3.807
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-13 a.
ANOVAa Fold Change
3.665 2 1.833 1.547 .228
39.099 33 1.185
42.764 35
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-13 a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
.773835 .444376 .273 -.34697 1.89465
.481847 .444376 .858 -.63896 1.60266
-.773835 .444376 .273 -1.89465 .34697
-.291989 .444376 1.000 -1.41280 .82882
-.481847 .444376 .858 -1.60266 .63896
.291989 .444376 1.000 -.82882 1.41280
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/- +/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
group = IL-13 a.
305 IL-17
Descriptivesa Fold Change
14 1.54399 .609871 .162995 1.19186 1.89612 .734 2.863
12 .70847 .254971 .073604 .54647 .87047 .252 1.118
14 .77036 .397830 .106325 .54066 1.00006 .087 1.334
40 1.02257 .588100 .092987 .83448 1.21065 .087 2.863
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-17 a.
ANOVAa Fold Change
5.881 2 2.940 14.300 .000
7.608 37 .206
13.489 39
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-17 a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
.835521* .178387 .000 .38817 1.28287
.773629* .171388 .000 .34383 1.20343
-.835521* .178387 .000 -1.28287 -.38817
-.061893 .178387 1.000 -.50924 .38545
-.773629* .171388 .000 -1.20343 -.34383
.061893 .178387 1.000 -.38545 .50924
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/- +/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = IL-17 a.
306 IL-1a
Descriptivesa Fold Change
10 1.52710 1.014902 .320940 .80109 2.25312 .591 3.379
10 .52118 .604917 .191292 .08844 .95391 .006 1.858
12 1.40974 .904029 .260971 .83535 1.98413 .269 2.832
32 1.16874 .945757 .167188 .82776 1.50972 .006 3.379
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-1a a.
ANOVAa Fold Change
6.175 2 3.087 4.154 .026
21.554 29 .743
27.728 31
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-1a a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
1.005928* .385545 .043 .02629 1.98556
.117364 .369131 1.000 -.82056 1.05529
-1.005928* .385545 .043 -1.98556 -.02629
-.888563 .369131 .068 -1.82649 .04937
-.117364 .369131 1.000 -1.05529 .82056
.888563 .369131 .068 -.04937 1.82649
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/- +/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = IL-1a a.
307 IL-1b
Descriptivesa Fold Change
13 6.35674 2.738818 .759611 4.70169 8.01179 3.553 13.618
11 7.81745 9.538129 2.875854 1.40965 14.22525 1.076 24.596
13 22.85307 22.311067 6.187977 9.37063 36.33551 1.514 69.067
37 12.58701 15.897344 2.613507 7.28657 17.88745 1.076 69.067
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-1b a.
ANOVAa Fold Change
2124.943 2 1062.471 5.180 .011
6973.177 34 205.093
9098.120 36
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-1b a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
-1.460713 5.866965 1.000 -16.23525 13.31383
-16.496331* 5.617191 .018 -30.64187 -2.35079
1.460713 5.866965 1.000 -13.31383 16.23525
-15.035618* 5.866965 .045 -29.81016 -.26108
16.496331* 5.617191 .018 2.35079 30.64187
15.035618* 5.866965 .045 .26108 29.81016
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = IL-1b a.
308 IL-2
Descriptivesa Fold Change
7 .75092 .508825 .192318 .28033 1.22150 .037 1.688
14 2.22455 1.769980 .473047 1.20260 3.24651 .342 5.943
21 1.73334 1.618864 .353265 .99644 2.47024 .037 5.943
+/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-2 a.
ANOVAa Fold Change
10.134 1 10.134 4.554 .046
42.280 19 2.225
52.414 20
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-2 a.
309 IL-3
Descriptivesa Fold Change
14 10.64912 5.131322 1.371403 7.68638 13.61186 3.285 19.499
13 5.44930 3.019112 .837351 3.62487 7.27373 .454 12.729
14 4.36573 1.789872 .478363 3.33229 5.39917 1.749 7.995
41 6.85485 4.492486 .701608 5.43684 8.27285 .454 19.499
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-3 a.
ANOVAa Fold Change
313.973 2 156.987 12.092 .000
493.324 38 12.982
807.297 40
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-3 a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
5.199822* 1.387779 .002 1.72397 8.67567
6.283390* 1.361837 .000 2.87251 9.69427
-5.199822* 1.387779 .002 -8.67567 -1.72397
1.083568 1.387779 1.000 -2.39228 4.55942
-6.283390* 1.361837 .000 -9.69427 -2.87251
-1.083568 1.387779 1.000 -4.55942 2.39228
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = IL-3 a.
310 IL-4
Descriptivesa Fold Change
14 9.44814 3.612702 .965535 7.36223 11.53405 2.918 16.260
14 1.69335 1.009233 .269729 1.11064 2.27606 .176 3.506
14 1.92515 .922024 .246421 1.39279 2.45751 .302 3.338
42 4.35555 4.245412 .655081 3.03258 5.67851 .176 16.260
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-4 a.
ANOVAa Fold Change
545.001 2 272.500 54.791 .000
193.964 39 4.973
738.965 41
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-4 a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
7.754791* .842906 .000 5.64613 9.86345
7.522988* .842906 .000 5.41433 9.63165
-7.754791* .842906 .000 -9.86345 -5.64613
-.231803 .842906 1.000 -2.34046 1.87686
-7.522988* .842906 .000 -9.63165 -5.41433
.231803 .842906 1.000 -1.87686 2.34046
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = IL-4 a.
311 IL-5
Descriptivesa Fold Change
13 21.01575 25.340013 7.028055 5.70294 36.32857 2.876 77.769
14 3.30235 3.295517 .880764 1.39958 5.20513 .029 12.297
14 15.09350 23.718675 6.339083 1.39875 28.78826 .983 89.508
41 12.94504 20.840585 3.254753 6.36694 19.52314 .029 89.508
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-5 a.
ANOVAa Fold Change
2213.136 2 1106.568 2.774 .075
15160.063 38 398.949
17373.199 40
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-5 a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
17.713400 7.693162 .081 -1.55500 36.98180
5.922250 7.693162 1.000 -13.34615 25.19065
-17.713400 7.693162 .081 -36.98180 1.55500
-11.791150 7.549352 .380 -30.69936 7.11706
-5.922250 7.693162 1.000 -25.19065 13.34615
11.791150 7.549352 .380 -7.11706 30.69936
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
group = IL-5 a.
312 IL-6
Descriptivesa Fold Change
14 57.21429 69.640141 18.612111 17.00527 97.42331 1.335 274.873
13 76.65380 72.963893 20.236543 32.56217 120.74544 7.576 228.752 14 286.29464 280.120515 74.865357 124.55787 448.03141 33.792 1020.611 41 141.60060 199.665219 31.182468 78.57848 204.62272 1.335 1020.611 -/-
+/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-6 a.
ANOVAa Fold Change
447638.9 2 223819.473 7.415 .002
1147009 38 30184.448
1594648 40
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-6 a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
-19.439519 66.917207 1.000 -187.04128 148.16224 -229.08036* 65.666308 .004 -393.54910 -64.61162 19.439519 66.917207 1.000 -148.16224 187.04128 -209.64084* 66.917207 .010 -377.24260 -42.03908 229.080357* 65.666308 .004 64.61162 393.54910 209.640838* 66.917207 .010 42.03908 377.24260 (J) genoty pe
+/- +/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = IL-6 a.
313 IL-9
Descriptivesa Fold Change
14 .89428 .251000 .067083 .74935 1.03920 .498 1.422
10 .65733 1.337433 .422933 -.29942 1.61407 .021 3.477
9 1.52002 2.162622 .720874 -.14232 3.18235 .006 5.716
33 .99313 1.347404 .234553 .51536 1.47090 .006 5.716
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = IL-9 a.
ANOVAa Fold Change
3.763 2 1.881 1.039 .366
54.333 30 1.811
58.096 32
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = IL-9 a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
.236950 .557202 1.000 -1.17597 1.64987
-.625740 .574976 .855 -2.08373 .83225
-.236950 .557202 1.000 -1.64987 1.17597
-.862690 .618339 .520 -2.43064 .70526
.625740 .574976 .855 -.83225 2.08373
.862690 .618339 .520 -.70526 2.43064
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
group = IL-9 a.
314 KC
Descriptivesa Fold Change
13 3.27493 1.754237 .486538 2.21485 4.33500 .404 6.500
13 8.60980 7.557836 2.096167 4.04264 13.17695 1.750 23.431
14 13.67384 10.474268 2.799366 7.62618 19.72151 2.075 33.904
40 8.64838 8.589750 1.358159 5.90125 11.39552 .404 33.904
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = KC a.
ANOVAa Fold Change
728.956 2 364.478 6.276 .004
2148.613 37 58.071
2877.568 39
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = KC a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
-5.334874 2.988970 .247 -12.83042 2.16067
-10.398919* 2.935110 .003 -17.75940 -3.03844
5.334874 2.988970 .247 -2.16067 12.83042
-5.064045 2.935110 .278 -12.42453 2.29644
10.398919* 2.935110 .003 3.03844 17.75940
5.064045 2.935110 .278 -2.29644 12.42453
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = KC a.
315 MIP-1a
Descriptivesa Fold Change
13 9.55345 7.945246 2.203615 4.75218 14.35471 2.920 33.690
7 10.39606 2.060396 .778756 8.49051 12.30161 7.434 12.847
2 2.00744 .754429 .533462 -4.77084 8.78572 1.474 2.541
22 9.13555 6.541356 1.394622 6.23528 12.03582 1.474 33.690
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = MIP-1a a.
ANOVAa Fold Change
115.012 2 57.506 1.394 .272
783.564 19 41.240
898.576 21
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = MIP-1a a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
-.842611 3.010611 1.000 -8.74578 7.06056
7.546006 4.877748 .415 -5.25860 20.35061
.842611 3.010611 1.000 -7.06056 8.74578
8.388617 5.148938 .359 -5.12789 21.90512
-7.546006 4.877748 .415 -20.35061 5.25860
-8.388617 5.148938 .359 -21.90512 5.12789
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
group = MIP-1a a.
316 MIP-1b
Descriptivesa Fold Change
13 5.06358 1.008175 .279617 4.45434 5.67281 3.090 6.971
8 8.11074 3.004582 1.062280 5.59885 10.62264 2.295 12.221
2 4.13192 .945869 .668830 -4.36638 12.63021 3.463 4.801
23 6.04245 2.433326 .507384 4.99020 7.09470 2.295 12.221
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = MIP-1b a.
ANOVAa Fold Change
53.979 2 26.990 7.076 .005
76.284 20 3.814
130.264 22
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = MIP-1b a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
-3.047164* .877598 .007 -5.33996 -.75436
.931662 1.483411 1.000 -2.94388 4.80720
3.047164* .877598 .007 .75436 5.33996
3.978826 1.543983 .054 -.05496 8.01261
-.931662 1.483411 1.000 -4.80720 2.94388
-3.978826 1.543983 .054 -8.01261 .05496
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = MIP-1b a.
317 RANTES
Descriptivesa Fold Change
10 5.62859 4.129808 1.305960 2.67430 8.58287 1.157 12.083
13 4.87179 5.206986 1.444158 1.72524 8.01834 .161 18.690
13 2.81443 1.440841 .399617 1.94374 3.68512 .959 5.408
36 4.33908 3.979588 .663265 2.99258 5.68558 .161 18.690
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = RANTES a.
ANOVAa Fold Change
50.537 2 25.268 1.655 .207
503.762 33 15.266
554.299 35
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = RANTES a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
.756797 1.643419 1.000 -3.38825 4.90185
2.814158 1.643419 .289 -1.33089 6.95921
-.756797 1.643419 1.000 -4.90185 3.38825
2.057361 1.532496 .566 -1.80792 5.92264
-2.814158 1.643419 .289 -6.95921 1.33089
-2.057361 1.532496 .566 -5.92264 1.80792
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
group = RANTES a.
318 TNF-A
Descriptivesa Fold Change
13 7.70673 8.939466 2.479362 2.30467 13.10880 1.830 34.314
13 2.55600 2.233045 .619335 1.20658 3.90541 .517 8.590
13 2.39292 1.435040 .398008 1.52573 3.26010 .540 4.975
39 4.21855 5.805977 .929700 2.33647 6.10063 .517 34.314
-/- +/- +/+
Total
N Mean Std. Dev iat ion Std. Error Lower Bound Upper Bound 95% Conf idence Interv al f or
Mean
Minimum Maximum
group = TNF-A a.
ANOVAa Fold Change
237.438 2 118.719 4.096 .025
1043.519 36 28.987
1280.956 38
Between Groups Within Groups Total
Sum of
Squares df Mean Square F Sig.
group = TNF-A a.
Post Hoc Tests
Multi ple Comparisonsa Dependent Variable: Fold Change
Bonf erroni
5.150736 2.111748 .059 -.15195 10.45342
5.313815* 2.111748 .049 .01113 10.61650
-5.150736 2.111748 .059 -10.45342 .15195
.163079 2.111748 1.000 -5.13961 5.46576
-5.313815* 2.111748 .049 -10.61650 -.01113
-.163079 2.111748 1.000 -5.46576 5.13961
(J) genoty pe +/-
+/+
-/- +/+
-/- +/- (I) genot y pe -/-
+/-
+/+
Mean Dif f erence
(I-J) St d. Error Sig. Lower Bound Upper Bound 95% Conf idence Interv al
The mean dif f erence is signif icant at the . 05 lev el.
*.
group = TNF-A a.