which option above is generally associated with fair weather

... representation on the basis of side scatter characteristics (SSC, y-axis) and CD14 expression (FITC-CD14, x-axis) is shown CD14-expressing population is easily distinguishable as gating region ... Importantly, after multivariate regression logistic analysis, persistent decreased expression was assessed to be in relation with the development of sepsis This is the first study in trauma patients ... logistic regression analysis indicated that low mHLA-DR expression was independently associated with the development of sepsis, whereas all the other parameters included in the analysis (ISS,

Ngày tải lên: 14/08/2014, 07:21

... patients with sepsis. Here we investigated temporal changes in platelet mitochondrial respiratory function in patients with sepsis during the first week after disease onset. Methods: Platelets were isolated ... Multiple organ failure (MOF) is the leading cause of death in patients with severe sepsis and septic shock [1]. The cause of MOF is largely unexplained and the patho- genesis is likely complex. Since ... unconscious. Eighteen patients with severe sepsis or septic shock, as previously defined [16], were included within 48 h after their admission to the ICU. Diagnosis of sepsis should have been made

Ngày tải lên: 14/08/2014, 07:21

... assumption of random mating This result is in agreement with those obtained by Ruiz et al (1991) in a Spanish natural population of D buzzatii However, our analysis is based on the assumption that ... From this analysis it may be concluded that a deficiency of 2st bearing individuals occurred in all cases These results could suggest gametic selection against 2st To test this hypothesis, flies ... the title and The English language of this was improved by the revision of Trang 8Dyzenchauz The critical comments of two anonymous reviewers also gratefully acknowledged This work was supported

Ngày tải lên: 14/08/2014, 20:20

... rural) is selected with probability proportional to size approach In the selected EAs an exhaustive listing of households is performed At the second stage, a predetermined 20 to 30 households is ... analysis were actually deficient Therefore, the analysis is liable to ecological fallacy and this could have underestimated the strength of association between the exposure and outcome It is important ... intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/

Ngày tải lên: 29/05/2020, 19:31

... technology Statistical analysis All the data analysis was conducted on SPSS 20.0 software package (SPSS, Chicago, IL) Pearson chi-square analysis or variance test was used to distin-guish differences ... This article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted use, distribution, ... regulating stress resistance, metabolism, cell cycle and cell apoptosis Meanwhile, it could make posi-tive response to environmental stimuli and prevent people from suffering the disease which related

Ngày tải lên: 17/06/2020, 17:07

... transcriptional activity within HNSCC tumours is associated with improved patient survival and better prognosis in a German population Simple HPV DNA detection alone did not demonstrate this association ... mechanisms by which lesions may arise The detection of HPV L1 sequences, by Linear Array or PCR amplifi-cation, is frequently performed and used as an indicator of HPV-related disease This has ... field, which stained strongly with the antibody This study demonstrates a significant correlation be-tween HPV status and prognosis, but this was restricted to mRNA expression alone Although this

Ngày tải lên: 21/09/2020, 01:35

... protein are associated with decreased survival of patients with metastatic disease [44] Similarly, increased tumoral expression of CXCL1 RNA is associated with metastatic disease, correlating with tumor ... of patients with stage III breast cancer still experience disease recurrence Disease recurrence for patients with late stage breast cancer is often accompanied by distant metastasis, contributing ... Sections were counter-stained with Harris’s hematoxylin for 5 minutes, dehydrated and mounted with Cytoseal Quantification of immunohistochemistry staining Immunohistochemistry staining was imaged

Ngày tải lên: 30/09/2020, 14:39

... significantly associated with mortality ICU admission and ETI performed in the surgical ward were significant factors for decreasing the risk of death within 30 days Trial registration: This trial ... anesthesiologist, and emer-gency treatments after ETI A previous study indicated that admission during the weekend was associated with a significantly increased mortality compared with midweek admission ... respiratory diseases, followed by cardiovascular diseases and neuro-logical diseases in our study, which was in accordance with a previous survey [13–15] However, the most common admitting diagnosis of

Ngày tải lên: 13/01/2022, 01:05

... associated with nasopharyngeal carcinoma (NPC), which has a high incidence in certain regions This study aimed to address how EBV variations contribute to the risk of NPC Methods: Using logistic ... available in this article, unless otherwise stated. Background Nasopharyngeal carcinoma (NPC) is a malignancy with a marked geographic distribution and ethnic tenden-cies, occurring with high frequencies ... closely associated with Hodgkin’s lym-phoma and some gastric cancers [8] The incidences of these malignancies show remarkably different geographic distributions [9], which is paradoxical in comparison

Ngày tải lên: 01/11/2022, 08:50

... Zn, is an important geochemical characteristic of ornithogenic lake sediments Overall the vertical distribution patterns of the elements analysed within the sediments were highly consistent with ... that is, the intensity of historical penguin activity The historical penguin population record around Lake Y2 was obtained from a Q-mode factor anal-ysis and our findings were consistent with ... analyses were performed within one month General analysis of sediment geochemical characteristics Each subsample was homogenised for the general analyses The pH was determined in distilled water and

Ngày tải lên: 19/11/2022, 11:44

... tumors in comparison with the also-upregulated expression of other HERV-K genes Analysis of reverse-phase protein array data indicated that increased expression of HERV-K is associated with decreased ... breast cancer is generally highly associated with epithelial-mesenchymal transition (EMT), and E-cadherin is down-regulated in EMT-related cancers However, E-cadherin expression is rarely lost ... HERVs have been associated with a variety of human diseases and disorders, but they are also believed to have potential for benefit to the host However, causal relationships with beneficial or

Ngày tải lên: 24/11/2022, 17:51

... lung tumorigenesis and development The expression level of SMC4 is highly variable in lung ADC (Fig. 2A), which is consistent with tumor heterogeneity We hypothesized that tumors with different ... Distinct from carcinogenesis, embryogenesis is a tightly regulated process The molecular regulation network in embryos is highly ordered, whereas the het-erogeneity of embryo tissue samples is ... lung ADC tissues and adjacent normal lung tissues and found that the expression level of SMC4 mRNA is 1.8-fold higher in 43 lung ADC tissues compared with their adjacent normal lung tissues (Two-tailed

Ngày tải lên: 04/12/2022, 16:37

... stained with 4¢,6-diamidino-2-phenylindole (blue). Trang 6is also associated with TIA-1 (Fig 3B), thereby indicat-ing that ASF⁄ SF2 can interact with both TIA proteins Western blot analysis on ... trea-ted with arsenite in combination with puromycin (data not shown) Furthermore, ASF⁄ SF2 co-localized exclu-sively with TIAR and not with Dcp1-positive Pbs [21], thereby confirming that ASF⁄ SF2 is ... capacity of both RRMs, whereas the RS domain is dispensable More-over, RRM1 but not RRM2 is necessary and sufficient to promote this cytoplasmic redistribution However, in the context of the wild-type

Ngày tải lên: 16/02/2014, 15:20

... expression with each of two different siRNAs is consis-tently associated with increased expression of HO-1 mRNA and protein Moreover, we provide evidence that at least three mechanisms may account ... induction of HO-1 mRNA In this con-text, we have reported that maximum induction of HO-1 mRNA expression was detected within 3 h by treatment with cadmium in HeLa cells, which is due to increased transcription ... independent experiments with similar results is shown. Trang 9detected in tissue homogenates prepared from multipletissues of HO-2–⁄ – mice [42] Thirdly, HO-1 protein is indeed over-expressed

Ngày tải lên: 19/02/2014, 05:20

... nucleotides [4] UCP2 is widely expressed in many tis-sues with high levels detected in the spleen, thymus, pancreatic b-cells, heart, lung, white and brown adi-pose tissue, stomach, testis and macrophages, ... haematopoiesis [18–20] The parent molecule of this family is muramyl dipeptide (MDP), which has been reported as the minimal adjuvant-active structure of bacterial peptidoglycan [21] However, MDP adminis-tration ... MDP The question raised at this stage is whether UCP2 is responsible for the increase in mitochondrial proton permeability (state 4) induced in macrophages after stimulation with MDP Purine nucleotides

Ngày tải lên: 05/03/2014, 23:20

... desensitized cells This is concomitant with a 50% reduction in ST-binding activity in desensitized cells Desensitization was correlated with a loss of the plasma membrane-associated, hyperglycosylated ... characteristic watery diarrhea that is associated with the ST peptides Recently, GC-C has also been shown to be involved in regulation of colonic cell proliferation [11] and apoptosis [12], and ... with serum-free DMEM/F12 and incubated with or without 10)7MSTh in DMEM/F12 for 9 h Monolayers were then washed and re-stimulated with fresh STh (10)7M) in the presence or absence of 500 lM isobutylmethyl

Ngày tải lên: 08/03/2014, 08:20

... stereoisomerism) The lower-®eld 1H NMR signal of 3 belonged to the N-methyl group at N2 in the E isomer and the higher-®eld signal to that in the Z isomer, in which N1is in trans and cis orientation ... an (N,N-dimethylacetimidoyl)amino group is present (Fig 8, structure 2) This group is linked to C5 of a legionaminic acid residue, which is substituted with a nonmethylated N-acetimidoyl group ... stereoisomers, E and Z, with regard to the partial double bond at N2, while the NMR spectra showed the presence of only one isomer Molecular modelling data (not shown) suggested that this isomer is

Ngày tải lên: 08/03/2014, 10:20

... expression by mechanisms different from direct protease inhibition HI-8 is the C-terminal domain of bikunin, which is active fragment for protease inhibitor but is not recognized by the cell-associated ... Equivalent Kd value was determined ( 1.6 nM), which is consistent with the known binding affinity of uPA for uPAR [5] In cells treated with PMA, cell-associated uPA-binding capacity was significantly ... reported that bikunin expression is associated with a less malignant phenotype [24] There is evidence that bikunin significantly prevented pulmonary metastasis of mouse Lewis lung carcinoma 3LL cells

Ngày tải lên: 17/03/2014, 11:20

... whose topology is dictated by a cis or trans peptide-bond conformation between residues 9 and 10, which correlates with the potency on insect or mammalian Navs We examined this hypothesis using Lqh3, ... suggesting that Lqh3 sensitivity to pH is associated with some later stage in the binding process to the channel This is corrobor-ated by previous binding studies, which demonstrcorrobor-ated that ... Whereas substitutions of His15, His36 and His43 did not reduce Lqh3 sensitiv-ity to pH, substitutions of His66 had a clear impact with the utmost decrease obtained with H66R (Table 3) Unexpectedly,

Ngày tải lên: 23/03/2014, 09:20

... mitochondrial preparations of A francis-canaembryos is fully functional ANT of A franciscana is refractory to inhibition by BKA As mentioned above, BKA was without an effect on Ca2+uptake rate ... d) failed to inhibit ANT operation as compared with the control (5 mm NH4OH, which is the vehicle of BKA, trace c) With the same BKA stocks, this poison fully inhibited ANT operation in rat liver ... untreated with ADP than in those treated with the nucleotide This is in line with the experimental findings on Ca2+uptake capacity in the presence and absence of adenine nucleotides Mitochondria isolated

Ngày tải lên: 29/03/2014, 00:20