... domain containing two “zinc fingers” (DBD), a hinge region containing the nuclear localization signal, and a carboxy-terminal ligand-binding domain (LBD) (Yen, 2001) Trang 19The amino-terminal ... dimerization interfaces in the upstream of the first zinc finger The retinoid X receptor (RXR) dimerization surfaces are located in the second zinc finger including an arginine located in the D box, ... zinc fingers, each composed of four cysteines coordinated with a zinc ion The integrity of each zinc finger is critical, as deletion of zinc fingers or amino acid substitution of these cysteine
Ngày tải lên: 16/09/2015, 12:08
... regulating embryo development in conifers is interesting from an evolutionary point of view However, our knowledge about the regulation of embryo development in conifers is limited During early ... regulating the cleavage process and for the development of a dominant embryo Results: RNA samples from embryos and megagametophytes at four early developmental stages during seed development inPinus ... de-velopment in Norway spruce [12] Microarray analysis has also been performed for studying global gene expres-sion during development of dominant zygotic embryos of maritime pine (Pinus pinaster)
Ngày tải lên: 22/05/2020, 05:02
Monochromatic light increases anthocyanin content during fruit development in bilberry
... production of different anthocyanidins in-cluding delphinidins (Dp), cyanidins (Cy), petunidins (Pt), peonidins (Pn) and malvidins (Mv) (Additional file 1) In bilberry fruits, the quantitative ... are novel in bilberry (cyanidin acetyl-3-O-galactose, malvidin acetyl-3-O-galactose, malvidin galactose, malvidin coumaroyl-3-O-glucose, delphinidin coumaroyl-3-O-galactose, delphinidin coumaroyl-3-O-glucose) ... kept in darkness The elevated levels of anthocyanins were mainly due to a significant increase in the accumulation of delphinidin glycosides A total of 33 anthocyanin compounds were detected in
Ngày tải lên: 26/05/2020, 23:25
Differences in microRNA expression during tumor development in the transition and peripheral zones of the prostate
... study indicate that the major differences in the transcription program are those arising during tumor development, rather than during normal tissue development In addition, tumors arising in the ... differ-ences in the transcription program are those arising during tumor development, rather than during normal tissue development In addition, tumors arising in the TZ have more unique differentially expressed ... strongly indicates that the major differences in the tran-scription program are those arising during tumor devel-opment, rather than during normal tissue development At the same time, the clustering
Ngày tải lên: 05/11/2020, 05:54
Molecular pathways undergoing dramatic transcriptomic changes during tumor development in the human colon
... only in the CRCs This gene set comprises 22 genes (32 RefSeqs) encoding cyclins, cyclin-dependent kinases (CDK), cyclin-cyclin-dependent kinase inhi-bitors (CDKI), and transcription factors, including ... surveillance guidelines vary depending in part on the size of the polyps removed In fact, individuals with 3 or more ad-enomas on initial colonoscopy, including 1 or more measuring ≥10 mm, are significantly ... of analyzing gene expression data have been developed to gain additional insight into the mechanisms driving the phenotypic differences One such approach involves the analysis not of single genes
Ngày tải lên: 05/11/2020, 08:09
limbic areas are functionally decoupled and visual cortex takes a more central role during fear conditioning in humans
... reduced coupling in some regions and the emerging centrality of others, contribute to the efficient processing of fear-relevant information during fear learning. Learning the contingency between ... upcoming US, increased excitability was also found at insula, a structure acti-vated in fear conditioning14 and during anticipation of painful stimuli in particular15 Taken together, we reported increased ... lobe, plays a more central role, during fear conditioning It remains to be investigated if the modality of the CS is indic-ative of re-routing information in the brain functional network Due to the
Ngày tải lên: 04/12/2022, 15:11
Transcriptomic and metabolomic characterization of post hatch metabolic reprogramming during hepatic development in the chicken
... Several amino acids, their derivatives, and waste products dif-fered in their abundance between days, including nine more abundant at D4 (arginine, lysine, threonine, cyst-eine, proline, ornithine, ... generate glycine from sarcosine, while GNMT interconverts sarcosine and glycine Sarcosine is an intermediate between glycine, creatine, and choline me-tabolism SDSL catabolizes serine to pyruvate ... (cysteine, proline, ornithine) Metab-olite data was not able to differentiate ornithine from ar-ginine, so we assume that one or both of them were more abundant at D4 Arginine, ornithine, and proline
Ngày tải lên: 23/02/2023, 18:22
báo cáo khoa học: " Validation of reference genes for quantitative real-time PCR during leaf and flower development in Petunia hybrida" pot
... geNorm, evaluating EF1a as the most reliable gene in line Mitchell but dif-fered in line V30, recommending ACT as the best candi-date EF1a suitability has been confirmed in potato during biotic and ... determina-tion of each gene to the BestKeeper index BestKeeper calculated the highest reliability for CYP in line Mitchell and V30 finding GAPDH as the least suitable gene in Mitchell and TUB in ... expansion in petals, or other flower tissues during this developmental stage, might explain the increased noise An alternative non-exclusive explanation is that the intermediate stages of flower development
Ngày tải lên: 12/08/2014, 03:21
báo cáo khoa học: " Cellular localization of ROS and NO in olive reproductive tissues during flower development" doc
... oxide (NO) are involved in the signalling processes taking place during the interactions pollen-pistil in several plants The olive tree (Olea europaea L.) is an important crop in Mediterranean ... during the main developmental stages of flowering Results Developmental stages of olive flowering Five major developmental stages were established to bet-ter scrutinize flower development in the olive ... and NO during flower development and the pollen-pistil interactions in the olive For this purpose, several of these molecules have been precisely localized in the stigma and the pollen during the
Ngày tải lên: 12/08/2014, 03:21
Báo cáo y học: "Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice" ppt
... the initiating pathway determines a distinctive expression phenotype in tumors In addition, using proteins as markers of cell phenotypes, we showed that initiating oncogenes determine the developmental ... activated in mammary tumors arising in mice infected with mouse mammary tumor virus (MMTV) [9,10] Wnt genes encode extracellular matrix bind-ing proteins that control many developmental processes, including ... alterations in MMTV-Wnt-1 transgenic mice The distinct patterns of genes expressed in MMTV-Wnt-1-induced and MMTV-Neu-MMTV-Wnt-1-induced tumors described in the preceding section suggest that initiating
Ngày tải lên: 14/08/2014, 14:22
Assessment of testis development during induced spermatogenesis in the european eel anguilla anguilla
... assess testis development in European eels during induced spermatogenesis, including (1) a description of the testis development in captive male Euro-pean eels given weekly hormonal injections and ... a better indicator of early development than the GSI, which remains low Both the SMI and GSI increase during the developing phase However, the SMI continued to increase as the males initiated ... pattern, including the rapid prolifer-ation of germ cells and the continuous development of gametes and sperm production The average SMI of the males in this study increased linearly during the
Ngày tải lên: 04/09/2015, 12:44
Investigation of miRNAs enrichment and degradation in bovine granulosa cells during follicular development
... degradation during bovine oocyte maturation which indicating the important potential role of miRNAs during the dynamic stage of follicular development The significance and involvement of miRNAs in the ... stimulating hormone (FSH; blue line), luteinizing hormone (LH; green lines), and progesterone (P4; orange line); and the pattern of growth of ovarian follicles during the estrous cycle in cattle ... the follicular basal lamina and a vivid increase in oocyte volume (Pedersen 1969) In consequence, during these acute periods, oocyte development is governed by paracrine interactions between the
Ngày tải lên: 25/11/2015, 15:17
Tracking the MiddleIncome Trap: What is It, Who is in It, and Why? Asian Development Bank ADB
... they have been in this income group over 14 years Eight out of the remaining 17 middle-income countries (i.e., not in the trap in 2010) are at the risk of falling into the trap (three into the lower ... middle-income and five into the upper middle-income) Trang 7two in the upper middle-income trap), six in Sub-Saharan Africa (all of them in the lower middle-income trap), three in Asia (two in the ... conclusions II Defining Income Groups Defining the middle-income trap starts with a definition what the middle-income is For this, a classification of countries that is relevant in the context of
Ngày tải lên: 29/11/2016, 10:16
What Happens When a Country Has an Absolute Advantage in All Goods
... has an absolute advantage in all aspects of camping: he is faster at carrying a backpack, gathering firewood, paddling a canoe, setting up tents, making a meal, and washing up So here is the question: ... Trang 1What Happens When aCountry Has an Absolute Advantage in All Goods By: OpenStaxCollege What happens to the possibilities for trade if one country has an absolute advantage in everything? ... exporting oil and importing lumber Trang 7Comparative Advantage Goes CampingTo build an intuitive understanding of how comparative advantage can benefit all parties, set aside examples that involve
Ngày tải lên: 31/10/2017, 17:27
Gonad development during sexual differentiation in hatchery-produced
... epinephelines are dominate in the trade in terms of both volume and value (Sadovy et al., 2003) Some epinephelines including the orange-spotted grouper (E coioides, as ‘E suillus’ or ‘E tauvina’ ... gonadal wall during sex-change Therefore, understanding the sexual pattern in the epinephelines requires considerable care and examination of a wide range of body sizes and ages, including both juvenile ... respectively Size variation within age groups was found in both species, indicating differences in growth rates; growth curves were presented inFig 1 3.2 Gonad development during sexual differentiation
Ngày tải lên: 25/08/2018, 12:14
Summary of Doctoral thesis: Innovating the model of economic zone development in the Quang Ninh province during international economic integration
... development in the Quang Ninh province during international economic integration Proposing a number of proposals, proposing renovation of economic zone development model in the Quang Ninh province during ... locality Since then, giving directions, views and proposing solutions to innovating the model of economic zone development in the Quang Ninh province during international economic integration ... ZONE IN THE LOCATION OF A PROVINCE LEVEL DURING INTERNATIONAL ECONOMIC INTEGRATION 2.1 Economic zone and economic zone development model in a level locality during international economic integration
Ngày tải lên: 11/01/2020, 14:28
An assessment of sustainable development in the South Central Coast of Vietnam during the period from 2010 to 2016
... Ngai Binh Dinh Phu Yen Khanh Hoa Ninh Thuan Binh Thuan Da Nang Quang Nam Quang Ngai Binh Dinh Phu Yen Khanh Hoa Ninh Thuan Binh Thuan Trang 10Table 3 PCI and the ranking of the SCC provinces in ... infrastructure development The sustainable development indicators can potentially contribute to apply to monitor the sustainable development in other coastal regions in Vietnam Keywords: Sustainable development, ... sustainable development 3.2 Scoring Methods The SIs contain two types of indicators [19], consisting of the positive indicators (indicator values positively affect the integrated index) and negative indicators
Ngày tải lên: 13/01/2020, 16:32
T cell immunity to enterovirus 71 infection in humans and implications for vaccine development
... vaccines against influenza virus could be increased by augmenting the affinity for the MHC molecules though exchanging amino acids in wild type sequences with non-proteogenic amino acids This in ... protection against viral infection [14] In addition, increasing number of studies are illustrating that EV-A71 inhibits production of IFNs at different points in the cell signaling pathways For ... immunity against EV-A71 infections Cellular Immunity and Vaccine Design Cellular cytokines such as interferon-gamma- inducible protein-10 (IP-10), IFN-γ and monokine induced by gamma interferon
Ngày tải lên: 15/01/2020, 05:10
Exploring miRNAs involved in blue/UV-A light response in Brassica rapa reveals special regulatory mode during seedling development
... binding site of miR156 and miR157 on sequences of candidate target genes in SPL family in mRNA sequence mRNA sequence of predicted binding site area Amino acid sequence of corresponding binding ... targets involved in the regulation of the light-induced photomorphogenic phenotype in seedlings ofBrassica rapa was identified, providing new insights into blue and UV-A light-responsive miRNAs in ... regulating anthocyanin production in response to various wavelengths of light To identify miRNAs involved in light-induced antho-cyanin biosynthesis in Brassica rapa, high-throughput sequencing technology
Ngày tải lên: 22/05/2020, 04:27
PnTgs1-like expression during reproductive development supports a role for RNA methyltransferases in the aposporous pathway
... early embryo development failure [17] Another interesting sequence mapped onto the ACR is a K homology (KH) domain-containing protein, which is an RNA-binding protein implicated in mRNA stability ... methyltransferase domain associated with a WW domain involved in protein-protein interactions (GRMZM2G347808, OS03T0396900 and AT1G45231, respectively in maize, rice and A thaliana) By taking advantage ... critical for development, including reproduction Our findings also suggest a pivotal role for this candidate gene in nucellar cell fate, as its diminished expression is correlated with initiation
Ngày tải lên: 27/05/2020, 00:20